• This study aims to describe the metabolomic fingerprints of plant-based diet indices (PDI) and examine their association with metabolic syndrome (MetS) and its components in a Danish population . (bvsalud.org)
  • The article presents a study that aims to identify shared biomarkers and pathways between systemic lupus erythematosus (SLE) and metabolic syndrome (MetS) using bioinformatics combining machine learning algorithm and single-cell sequencing analysis. (fullpicture.app)
  • The objective was to examine the effects of blueberry supplement consumption on metabolic syndrome (MetS) parameters and potential underlying mechanisms of action. (nih.gov)
  • Both NAFLD and mental disorders share pathophysiological pathways, and also present a complex, bidirectional relationship with the metabolic syndrome (MetS) and related cardiometabolic diseases. (biomedcentral.com)
  • This study uses a cohort sample of 12,644 to 13,832 mother-child pairs from the UK Born in Bradford Study to examine the associations between maternal metabolic syndrome classification (MetS) and child development outcomes at age 5, using cord blood markers as candidate mediators. (biomedcentral.com)
  • Metabolic syndrome (MetS) is associated with several degenerative diseases, including retinal degeneration. (molvis.org)
  • Background: Metabolic syndrome (MetS), prediabetes (PreDM) and metabolic-associated fatty liver disease (MAFLD) share pathophysiological pathways concerning type 2 diabetes mellitus (T2DM) onset. (unav.edu)
  • The non-invasive assessment of MAFLD combined with PreDM and MetS features might provide further accuracy in predicting hyperglucaemic status with the description of singular clinical phenotypes.Methods: A retrospective cohort study was performed on 2799 patients recruited in the Vascular-Metabolic CUN cohort. (unav.edu)
  • These phenotypes provided independent capacity of prediction of T2DM incidence after adjustment for age, sex, tobacco and alcohol consumption, obesity and number of SMet features with a c-Harrell=0.84.Conclusions: MAFLD interplay with MetS and PreDM might help to discriminate patient risk of T2DM in the clinical setting through metabolic remodelling-based phenotypes. (unav.edu)
  • Our work involves population and family-based genetic studies, high throughput sequencing to identify disease genes, with a focus on coronary artery disease (CAD) and metabolic syndrome (MetS). (yale.edu)
  • By recruiting more than thousand kindreds with early onset CAD and multiple metabolic risk factors for genetics and metabolic studies we have been able to map, identify and characterize a dozen of human disease genes for CAD and MetS, which have been reported in leading journals such as Nat Genet, Science, NEJM, Cell Metab, JCI, PNAS, AJHG, etc. (yale.edu)
  • Specific gut bacteria seem to serve as lipopolysaccharide (LPS) sources and several reports claim a role for increased intestinal permeability in the genesis of metabolic disorders. (springer.com)
  • Hotamisligil GS (2001) Inflammation and metabolic disorders. (springer.com)
  • It also analyzes the link between NAFLD and psychiatric disorders, looking into common pathophysiological pathways, such as metabolic, genetic, and lifestyle factors. (biomedcentral.com)
  • NAFLD is part of a complex system of mental and non-communicable somatic disorders with a common pathogenesis, based on shared lifestyle and environmental risks, mediated by dysregulation of inflammation, oxidative stress pathways, and mitochondrial function. (biomedcentral.com)
  • The current systematic review and meta-analysis of randomized controlled trials (RCTs) was carried out to assess the influence of curcumin intake on weight among patients with metabolic syndrome and related disorders. (frontiersin.org)
  • Overall, we have found that curcumin intake among patients with metabolic syndrome and related disorders was correlated with a significant reduction in BMI, weight, WC, and leptin, and a significant increase in adiponectin levels, but did not affect HR. (frontiersin.org)
  • For example, sleep-related breathing disorders, such as obstructive sleep apnea, are becoming increasingly relevant and novel risk factors for metabolic syndrome. (medscape.com)
  • Deregulation of the MAPK signaling occurs under many pathological conditions including neurodegenerative disorders, metabolic syndromes and cancers. (mdpi.com)
  • Lysosomal function is critical for organismal homeostasis-mutations in genes encoding lysosomal proteins cause severe human disorders known as lysosomal storage diseases, and lysosome dysfunction is implicated in age-associated diseases including cancer, neurodegeneration and metabolic syndrome. (stanford.edu)
  • Whole-body inhalation of PEPs perturbed transcriptional activities associated with cardiovascular dysfunction, metabolic syndrome, and neural disorders at every observed time point in both rat lung and blood during the 21 days of exposure. (cdc.gov)
  • Role of the cystathionine β-synthase / H2S pathway in the development of cellular metabolic dysfunction and pseudohypoxia in down syndrome. (helsinki.fi)
  • By developing novel tools and harnessing the power of metabolomics, proteomics and functional genomics, our lab will define 1) how the lysosome communicates with other cellular compartments to fulfill the metabolic demands of the cell under various metabolic states, 2) and how its dysfunction leads to rare and common human diseases. (stanford.edu)
  • We apply this knowledge to understand how lysosomal dysfunction leads to human diseases including neurodegeneration, cancer and metabolic syndrome. (stanford.edu)
  • expertise to identify causal links between obesity and metabolic dysfunction in nutrition, metabolic factors, and cancer. (who.int)
  • [ 1 , 2 ] A study by Stuebe et al found this condition to be associated with persistent metabolic dysfunction in women at 3 years after delivery, separate from other clinical risk factors. (medscape.com)
  • These two biomarkers show positive correlations with the pathways for the metabolism of xenobiotics and cholesterol, both of which are active in this comorbidity. (fullpicture.app)
  • RNA-sequence analysis revealed that curcumin intake affected hepatic lipid metabolism via the peroxisome proliferator-activated receptor (PPAR) pathway, especially PPARα activation, resulting in increased Apoa2 mRNA expression. (elifesciences.org)
  • When activated, the PPAR gamma pathway promotes lipid metabolism. (sages.org)
  • The chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed through a series of steps into another chemical, each step being facilitated by a specific enzyme. (wikipedia.org)
  • A striking feature of metabolism is the similarity of the basic metabolic pathways among vastly different species. (wikipedia.org)
  • Amino acids also contribute to cellular energy metabolism by providing a carbon source for entry into the citric acid cycle (tricarboxylic acid cycle), especially when a primary source of energy, such as glucose, is scarce, or when cells undergo metabolic stress. (wikipedia.org)
  • Akt pathways have effects on apoptosis, protein synthesis, metabolism and cell cycle. (springer.com)
  • One of the goals of his research - The mechanistic Target of Rapamycin: The grand conducTOR of metabolism and aging - is to determine whether pathways like TOR can be regulated to treat the diseases of aging. (lifeboat.com)
  • The pathway through which arterial stiffness caused metabolism syndrome could be partly explained by an increase in fasting insulin (12% contribution) and low-density lipoprotein cholesterol (9% contribution). (worldhealth.net)
  • Specifically, Brian's lab focuses on cardiovascular disease and metabolic syndromes like type II diabetes. (lifeboat.com)
  • Improving these pathological conditions, especially obesity, is major therapeutic goals for treating metabolic syndrome. (hindawi.com)
  • Natural remedies are currently attracting more attention as therapeutic or protective agents for treating metabolic syndrome [ 5 ]. (hindawi.com)
  • We also study how these pathways go awry in human diseases such as cancer, neurodegeneration and metabolic syndrome, in order to engineer new therapeutic modalities. (stanford.edu)
  • Due to the significance of impaired autophagy in these diseases, there is increased interest in studying pathways and targets involved in maintaining efficient autophagic functions as potential therapeutic targets. (hindawi.com)
  • We leverage modern techniques of functional genomics, epigenetics, transcriptomics, proteomics, gene editing and model-driven experimentation to understand the underlying causes of atherosclerosis and metabolic syndrome and discover therapeutic targets. (yale.edu)
  • these pathways are associated with activation of pathways like cellular oxidative stress response, inflammation, apoptosis, and phototransduction, although the changes were more prominent in WNIN/GR-Ob than in WNIN/Ob animals. (molvis.org)
  • In this review, we studied on the effects and molecular mechanisms of Rhizoma coptidis on NF-κB/MAPK/PI3K-Akt/AMPK/ERS and oxidative stress pathways. (springer.com)
  • Evidence presented in this review implicated that Rhizoma coptidis exerted beneficial effects on various diseases by regulation of NF-κB/MAPK/PI3K-Akt/AMPK/ERS and oxidative stress pathways, which support the clinical application of Rhizoma coptidis and offer references for future researches. (springer.com)
  • Oxidative stress pathways are caused by the imbalance of oxidation and antioxidation in body. (springer.com)
  • Oxidative stress pathways regulate redox balance by Nrf2 and other ways. (springer.com)
  • In this review, we sorted out the relationship of Rhizoma coptidis among components, diseases and NF-κB/MAPK/PI3K/Akt/AMPK/ERS/oxidative stress pathways, systematically studying on how Rhizoma coptidis exerts beneficial effects to various diseases, which supported the clinical application of Rhizoma coptidis and provided references for the future researches. (springer.com)
  • It has also been reported that triiodothyronine (T3) alleviates oxidative stress, inflammation and apoptosis caused by hepatic ischemia-reperfusion injury, and its mechanism of action is associated with negative regulation of the NLRP3 signaling pathway ( 10 ). (spandidos-publications.com)
  • Plasma metabolomic profiles of plant-based dietary indices reveal potential pathways for metabolic syndrome associations. (bvsalud.org)
  • Using the Ingenuity program, potential pathways were identified and real-time quantitative RT-PCR (QPCR) was used to validate the array data. (sages.org)
  • Some members of Rhododendron genus are traditionally used as medicinal plants for arthritis, acute and chronic bronchitis, asthma, pain, inflammation, rheumatism, hypertension and metabolic diseases. (medsci.org)
  • With obesity rates projected to continue rising globally, there is an urgent need to understand the intricate mechanisms that contribute to metabolic diseases such as diabetes. (news-medical.net)
  • Brian also studies the genetic mutations underlying diseases such as dilated cardiomyopathy , muscular dystrophy , and Hutchinson-Gilford Progeria Syndrome , which resembles premature aging. (lifeboat.com)
  • With the understanding that some diseases such as obesity are metabolic syndromes in which multiple biochemical pathways interact to cause complex symptoms, metabolic testing offers a way to gauge health over a lifetime. (3quarksdaily.com)
  • Also see the Medscape Drugs & Diseases article Eosinophilia-Myalgia Syndrome . (medscape.com)
  • therefore, their consumption can play a role ing to the World Health Organization, the global preva- in developing chronic diseases ( 10 , 12 ) and obesity ( 13 ), as lence of childhood obesity has increased from 31 million well as increased risk of metabolic syndrome and total children in 1990 to 42 million in 2013 ( 5 ). (who.int)
  • A new research led by Tokyo Medical and Dental University (TMDU) in chemically induced mouse model of inflammatory bowel disease (IBD) reveals the role of protein signaling pathway in the generation of macrophages that may induce inflammation in the colon. (medindia.net)
  • A team of Japanese scientists led by Tokyo Medical and Dental University (TMDU) used a chemically induced mouse model of IBD to show that a protein signaling pathway is crucial to the generation of macrophages that cause colonic inflammation. (medindia.net)
  • This shows the importance of the IFNγ-Stat1 signaling pathway in colonic inflammation. (medindia.net)
  • Consuming a diet rich in saturated fats triggers persistent, low-level inflammation within the body, ultimately contributing to the onset of metabolic syndrome. (medindia.net)
  • Emerging data indicate that gut-derived endotoxin (metabolic endotoxemia) may contribute to low-grade systemic inflammation in insulin-resistant states. (springer.com)
  • Cani PD, Bibiloni R, Knauf C et al (2008) Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. (springer.com)
  • These results indicate for the first time that KYN and indole TRP metabolic pathways are concomitantly altered in obese subjects and highlight their respective associations with obesity-related systemic inflammation. (frontiersin.org)
  • NF-κB pathways are associated with immunity, inflammation and cell survival. (springer.com)
  • The signaling pathway enhances access to the promoters of genes encoding inflammatory mediators, thus increasing their expression. (medindia.net)
  • The study identifies 153 shared feature genes enriched in immune- and metabolic-related pathways. (fullpicture.app)
  • It also screens 20 shared hub genes that are associated with immunological and metabolic processes in peripheral blood and successfully builds a prognostic model using these genes. (fullpicture.app)
  • Differentially regulated genes were clustered in immune-related pathways. (nih.gov)
  • Specifically, the PPAR gamma pathway from obese patients showed an increased number of genes that were dysregulated including TNF alpha. (sages.org)
  • These dysfunctional genes engender a cascade of pathophysiology that contributes to the complications associated with the metabolic syndrome. (sages.org)
  • Subsequent molecular and physiological studies in human mutation carriers and animal models have allowed us to unravel novel functions of the identified genes, to delineate their cognate pathways and to discover new targets for pharmaceutical intervention. (yale.edu)
  • Overall, the identified PEPs-induced dysregulated genes, molecular pathways and functions, and miRNA-mediated transcriptional activities provide important insights into the disease mechanisms. (cdc.gov)
  • Therefore, we evaluated the effect of ACE on major manifestations of metabolic syndrome including obesity, hyperlipidemia, and fatty liver using a high-fat diet mouse model. (hindawi.com)
  • In this study, the effects of R. oldhamii leaf extract on inhibiting the free fatty acid (FFA)-induced accumulation of fat in HepG2 cells and on improving fatty liver syndrome in mice with high fat diet (HFD)-induced NAFLD were investigated. (medsci.org)
  • In addition, the EtOAc fraction of R. oldhamii leaf significantly improved fatty liver syndrome and reduced total cholesterol (TC) and triglyceride (TG) in HFD-induced NAFLD mice at a dosage of 200 mg/kg BW. (medsci.org)
  • AMPK pathways inhibit biosynthetic pathways with energy consumption, such as protein, fatty acid and glycogen synthesis. (springer.com)
  • One of our groundbreaking discoveries was the identification of founder mutations in the DYRK1B gene, underlying atherosclerosis, metabolic syndrome, and fatty liver disease. (yale.edu)
  • Cross-talk of the MAPK signaling pathway with other proteins and signaling pathways have a crucial impact on clinical outcomes of targeted therapies and plays important role during development of drug resistance in cancers. (mdpi.com)
  • Clinical-Grade Patches as a Medium for Enrichment of Sweat-Extracellular Vesicles and Facilitating Their Metabolic Analysis. (helsinki.fi)
  • Obesity, a highly prevalent disorder and central diagnosis of the metabolic syndrome, is linked to mental health by clinical observations and biological pathways. (researchgate.net)
  • A comprehensive review in the journal Cell provides an in-depth look at the biology, clinical outcomes, and treatment options for menopause, including the effects of hormonal changes on metabolic and cognitive functions. (news-medical.net)
  • The researchers also determined that this biomarker, a protein known as "neuronal regeneration related protein" (or NREP), plays a significant role in the regulation of a pathway that is currently being reviewed in clinical trials as a treatment option for the disease. (agemed.org)
  • Early intervention might likely reduce high fasting insulin and low-density lipoprotein cholesterol thereby cutting off 20% of the potential causal effect of arterial stiffness on metabolic syndrome," says Andrew Agbaje, a physician and clinical epidemiologist at the University of Eastern Finland. (worldhealth.net)
  • In this study we evaluated the effect of the water extract of a mixture of A. iwayomogi and C. longa (ACE) on high-fat diet-induced metabolic syndrome in a mouse model. (hindawi.com)
  • To address variation between professional guidelines, the NHLBI, AHA, International Diabetes Foundation (IDF), and others have proposed a harmonized definition of metabolic syndrome. (medscape.com)
  • Metabolic syndrome increases the risk of worsening obesity, type 2 diabetes, cardiovascular disease, and premature death. (worldhealth.net)
  • We are seeing for the first time that arterial stiffness in adolescents is an unknown risk factor for metabolic syndrome which may initiate a cascade of disease processes that might lead to type 2 diabetes, cardiovascular disease, and premature death. (worldhealth.net)
  • Diabetes & metabolic syndrome 2022 0 0. (cdc.gov)
  • Diabetes and metabolic syndrome as risk factors for COVID-19. (cdc.gov)
  • SIRD is a novel form of diabetes representing the most insulin resistant (both hepatic and peripheral) form, with most features of the metabolic syndrome but also hepatic steatosis. (lu.se)
  • Ultimately, obesity results from a long-standing imbalance between energy intake and energy expenditure, including energy utilization for basic metabolic processes and energy expenditure from physical activity. (msdmanuals.com)
  • By age 7, common variations in FTO, TMEM18 and NRXN3 influence the vulnerability to metabolic complications of sleep deprivation. (nature.com)
  • Extracellular signal-regulated kinase (ERK) is a part of the mitogen-activated protein kinase (MAPK) signaling pathway which allows the transduction of various cellular signals to final effectors and regulation of elementary cellular processes. (mdpi.com)
  • The Abu-Remaileh Lab is interested in identifying novel pathways that enable cellular and organismal adaptation to metabolic stress and changes in environmental conditions. (stanford.edu)
  • Lysosomes are membrane-bound compartments that degrade macromolecules and clear damaged organelles to enable cellular adaptation to various metabolic states. (stanford.edu)
  • MAPK pathways refer to various cellular functions, including cell proliferation, differentiation and migration. (springer.com)
  • one group had a genetic modification to have the markers of metabolic syndrome. (agemed.org)
  • They took a deep dive into the genetic pathways that were active in the healthy offspring versus the offspring that developed NAFLD. (agemed.org)
  • Causes of obesity are multifactorial and include genetic predisposition and behavioral, metabolic, and hormonal influences. (msdmanuals.com)
  • The medicinal plants Artemisia iwayomogi ( A. iwayomogi ) and Curcuma longa ( C. longa ) radix have been used to treat metabolic abnormalities in traditional Korean medicine and traditional Chinese medicine (TKM and TCM). (hindawi.com)
  • The results from this study suggest that ACE has the pharmaceutical potential reducing the metabolic abnormalities in an animal model. (hindawi.com)
  • In traditional Korean medicine (TKM) and traditional Chinese medicine (TCM), metabolic abnormalities are considered indicative of " dampness/phlegm " ( 濕痰 ) and " blood stasis " ( 瘀血 ) [ 6 ]. (hindawi.com)
  • The overall strategic vision clear links to nutrition and metabolic combines large-scale population-based of NME is based on three major research abnormalities and for which much remains studies with laboratory and biostatistical themes: (i) understanding the role of to be discovered about disease etiology. (who.int)
  • AMPK pathways are energy regulation pathways. (springer.com)
  • Induction of canonical autophagy is mainly controlled by the AKT/mTOR and AMPK signaling pathways and relies on the activation and assembly of two macromolecular complexes, the ATG1/ULK1 and the Class III phosphatidylinositol 3-kinase (PI3K) complex (Figure 1 ) [ 5 ]. (hindawi.com)
  • Targeted inhibition of individual kinases of the MAPK signaling pathway using synthetic compounds represents a promising way to effective anti-cancer therapy. (mdpi.com)
  • We discuss cross-talk of the MAPK/ERK signaling pathway with other signaling pathways, in particular interplay with the Hippo/MST pathway. (mdpi.com)
  • A previous cohort study reported a strong relationship between metabolic syndrome and an increased risk of mortality [ 2 ]. (hindawi.com)
  • Using insights from our research, we will engineer novel therapies to modulate the pathways that govern human disease. (stanford.edu)
  • Currently, Brian studies the pathways that modulate longevity in life forms ranging from yeast to mice. (lifeboat.com)
  • Acylated ghrelin treatment reversed TGF-& beta;1-induced myofibroblast-like phenotype, collagen contractile properties, and the upregulation of factors involved in HSC activation and fibrogenesis via PI3K/Akt/mTOR pathway. (unav.edu)
  • Accessible Version: www.cdc.gov/pcd/issues/2022/21_0231.htm to estimate the effect of anthropometric risk factors on the preval- ence of metabolic syndrome. (cdc.gov)
  • With an enzyme defect, carbohydrate metabolic pathways are blocked, and excess glycogen accumulates in affected tissues. (medscape.com)
  • It also finds that too little natural light can alter how fat cells behave and may increase the risk of metabolic syndrome. (medicalnewstoday.com)
  • Studies comparing ethnically similar populations exposed to different dietary environments have suggested that westernized diets are strongly associated with a higher risk of developing metabolic syndrome. (medscape.com)
  • This section provides structured guidance on how to do a brief but effective nutritional assessment for malnutrition and obesity (metabolic syndrome risk). (plymouth.ac.uk)
  • Arterial stiffness may be a novel risk factor for metabolic syndrome in teens, a paper published in the American Journal of Physiology-Heart and Circulatory Physiology concludes. (worldhealth.net)
  • During the 7-year follow-up, worsening arterial stiffness was associated with a 9% risk of metabolic syndrome in males but there was no statistically significant risk among females. (worldhealth.net)
  • There is an association between low levels of B12 in the bloodstream during pregnancy and an increased risk for preeclampsia, though research suggests that it is likely due to shared metabolic pathways rather than a direct relationship. (preeclampsia.org)
  • Risk Factors and Metabolic Syndrome Among Adults in India: A We searched databases PubMed Central, EMBASE, MEDLINE, Systematic Review and Meta-Analysis of Observational Studies. (cdc.gov)
  • Several studies have explored the effect of anthropometric risk ing central obesity, atherogenic dyslipidemia (ie, low high-density factors on metabolic syndrome. (cdc.gov)
  • Analyses of abdominal adiposity and metabolic syndrome as risk factors for respiratory distress in COVID-19. (cdc.gov)
  • HsIL-6 and hsCRP were increased in obesity and were overall associated with TRP metabolic pathways alterations. (frontiersin.org)
  • [ 99 ] each of which may produce favorable metabolic alterations as single agents in patients with metabolic syndrome. (medscape.com)
  • Consistent with this notion, activation of the KYN pathway has been documented in several studies conducted in obese subjects ( 16 - 19 ). (frontiersin.org)
  • ERS pathways are triggered by the unbalance of ER environment, including hypoxia, disturbance of Ca 2+ homeostasis and glucose starvation. (springer.com)
  • One of the causative factors that has been suggested is the parental influence in the offspring, in the sense that if either the mother or the father [or particularly both] has metabolic syndrome (a medical condition associated with obesity, high blood glucose, high cholesterol, and elevated insulin levels) then the chances of the offspring developing this disease is greater," says Dr. Kulkarni. (agemed.org)
  • Arterial stiffness was measured with carotid-femoral pulse wave velocity and the presence of any three of high blood pressure, high trunk fat mass, high fasting glucose, high fasting triglyceride, or low fasting high-density lipoprotein cholesterol was considered to describe metabolic syndrome. (worldhealth.net)
  • Fasting blood gene expression profiles and plasma metabolomic profiles were examined at baseline and week 8 to assess metabolic changes occurring in response to the BBP. (nih.gov)
  • The protein produced from this gene turns on signaling pathways involved in the development and function of immune system cells called lymphocytes. (medlineplus.gov)
  • Vitamin D Deficiency and COVID-19: A Biological Database Study on Pathways and Gene-Disease Associations. (cdc.gov)
  • Furthermore, Lycium barbarum has been reported to inhibit the NLRP3 inflammasome signaling pathway, thereby reducing alcohol-induced liver cell damage ( 11 ). (spandidos-publications.com)
  • When we decreased NREP levels in human liver cells, the cholesterol pathway and markers associated with the development of fibrosis went up resembling what happens during the progression of NAFLD" says Dr. Kulkarni. (agemed.org)
  • Alcoholic liver disease (ALD), characterized by liver metabolic disorder, is an acute, chronic liver injury caused by long-term heavy drinking ( 1 ). (spandidos-publications.com)
  • Methods Circulating (n = 179) and hepatic expression (n = 95) of ghrelin and LEAP-2 were measured in patients with severe obesity and available liver pathology analysis undergoing Roux-en-Y gastric bypass (RYGB). (unav.edu)
  • Obesity and metabolic syndrome are being increasingly implicated and associated with younger ages and greater metabolic severity. (cassiopaea.org)
  • To identify targetable mechanisms and pathways underlying initiation and progression of SIRD. (lu.se)
  • CRISPR correction of the Finnish ornithine delta-aminotransferase mutation restores metabolic homeostasis in iPSC from patients with gyrate atrophy. (helsinki.fi)
  • Eosinophilia-myalgia syndrome (EMS) was first recognized in 1989 in New Mexico in 3 patients who had an illness with a unique array of symptoms, including peripheral blood eosinophilia and severe myalgias. (medscape.com)
  • Most patients experience muscle symptoms, such as weakness and cramps, although certain GSDs manifest as specific syndromes, such as hypoglycemic seizures or cardiomegaly. (medscape.com)
  • The image below illustrates the metabolic pathways for carbohydrates. (medscape.com)
  • Metabolic pathways of carbohydrates. (medscape.com)
  • Obesity is a metabolic disorder characterized by a chronic low-grade inflammatory state, as reflected in increased levels of circulating inflammatory markers, including pro-inflammatory cytokines and the acute phase protein C-reactive protein (CRP) ( 1 - 4 ). (frontiersin.org)
  • Due to the normal metabolic rate of humans catabolysis becomes life-threatening only after 1-2 months from the cessation of nutrition going into the body. (wikipedia.org)
  • Machine Learning and Pathway Analysis-Based Discovery of Metabolomic Markers Relating to Chronic Pain Phenotypes. (helsinki.fi)
  • After adjusting for maternal, child, and environmental covariates, maternal metabolic syndrome classification during pregnancy was associated with children's LIT domain through direct effects of maternal metabolic health and indirect effects of cord blood markers (total effects), and COM and PSE domains via changes only in a child's cord blood markers (total indirect effects). (biomedcentral.com)
  • We encourage you to follow and use locally developed and agreed guidance and pathways for identifying and managing malnutrition. (plymouth.ac.uk)