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  • investigate
  • An estimated 230,480 women were diagnosed with invasive breast cancer last year, which is why epidemiologist Susan Hankinson has made it her mission to investigate the "underlying etiology and biologic pathways" that lead to the cancer's development. (umass.edu)
  • Supported are studies that investigate these pathways from a whole-body perspective as well as within specific tissues (e.g., liver, fat, muscle) and at the cellular and molecular level. (nih.gov)
  • binds
  • In a cAMP-dependent pathway, the activated G s alpha subunit binds to and activates an enzyme called adenylyl cyclase , which, in turn, catalyzes the conversion of ATP into cyclic adenosine monophosphate (cAMP). (wikipedia.org)
  • The pathway is triggered when the C3b protein directly binds a microbe . (wikipedia.org)
  • cancer
  • Castellano G, Malaponte G, Mazzarino MC, Figini M, Marchese F, Gangemi P et al (2008) Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression. (springer.com)
  • If cAMP-dependent pathway is not controlled, it can ultimately lead to hyper-proliferation, which may contribute to the development and/or progression of cancer . (wikipedia.org)
  • activate
  • Some caspases are activated by fas in the pro-apoptosis cell pathway, and then go on to activate further caspases (caspase 3), which induce apoptosis, while others interact with Apaf-1 in other cell pathways. (bioportfolio.com)
  • regulation
  • The following pages describe the pathways to sound energy policy, smarter and more effective regulation of industry operations, onshore and offshore - all for managing the safe energy development America needs today and well into the future. (api.org)
  • site
  • ProDiscover Basic is available for download from the Resource Section of the Technology Pathways web site at http://www.techpathways.com . (prweb.com)
  • another
  • Subsequently, another team was formed for the Craniotomy for Ruptured Aneurysm Pathway. (asha.org)
  • A neural pathway connects one part of the nervous system to another using bundles of axons called tracts. (wikipedia.org)
  • A neural pathway is the connection formed by axons that project from neurons to make synapses onto neurons in another location, to enable a signal to be sent from one region of the nervous system to another. (wikipedia.org)
  • The exo to endo conversion is identified to be energetically more favorable than another pathway emanating from the left handed helical FPP. (scoop.it)
  • include
  • Consistent with CQI philosophy, pathway development teams must have input from all process stakeholders, so they typically include representatives of the patient population and a variety of caregivers. (asha.org)
  • [ citation needed ] This naming can extend to include any number of structures in a pathway, such that the cerebellorubrothalamocortical pathway originates in the cerebellum , synapses in the red nucleus ("ruber" in Latin), on to the thalamus , and finally terminating in the cerebral cortex . (wikipedia.org)
  • While it doesn't include all the features of the rest of the product family, ProDiscover Basic can be used to work a complete case" according to Christopher L.T. Brown, founder and CTO of Technology Pathways. (prweb.com)
  • Services
  • Technology Pathways, LLC is a leading edge provider of computer and network security tools and services for the Corporate IT, government, education, and legal communities. (prweb.com)
  • Cell
  • In the field of molecular biology , the cAMP-dependent pathway , also known as the adenylyl cyclase pathway , is a G protein-coupled receptor -triggered signaling cascade used in cell communication . (wikipedia.org)
  • data
  • Critical pathways are grounded in CQI methodology and use its scientific tools, such as teams, flowcharts, data collection, analysis of variance, and so. (asha.org)
  • materials
  • Curriculum Pathways is a web-based learning environment that uses proven instructional strategies and techniques - such as integrating primary-source materials and providing a broad, holistic context for specific learning concepts and skills. (sas.com)
  • life
  • Working with colleagues at Baystate Medical Center and Joseph Jerry at the Pioneer Valley Life Sciences Institute , Hankinson is hoping to identify some of the underlying biologic pathways responsible for the early life adiposity association. (umass.edu)
  • cAMP-dependent pathway is necessary for many living organisms and life processes. (wikipedia.org)
  • help
  • We want to help the smaller law enforcement departments and agencies that need computer forensics capability, but can't afford it," stated Steve Richardson, President & CEO of Technology Pathways. (prweb.com)
  • small
  • This convertase, the alternative pathway C3-convertase, although only produced in small amounts, can cleave multiple C3 proteins into C3a and C3b. (wikipedia.org)
  • Target
  • Specificity of signaling between a GPCR and its ultimate molecular target through a cAMP-dependent pathway may be achieved through formation of a multiprotein complex that includes the GPCR, adenylyl cyclase, and the effector protein. (wikipedia.org)
  • role
  • Extensive conformational sampling of all key intermediates along the biosynthetic pathway offered new insight into the role of the isoprenyl side chain conformation in the formation of santalene and its analogues. (scoop.it)
  • directly
  • Mossy fibers project directly to the deep nuclei , but also give rise to the following pathway: mossy fibers → granule cells → parallel fibers → Purkinje cells → deep nuclei. (wikipedia.org)
  • The other main pathway is from the climbing fibers and these project to Purkinje cells and also send collaterals directly to the deep nuclei. (wikipedia.org)
  • This pathway can also be activated downstream by directly activating adenylyl cyclase or PKA. (wikipedia.org)