Pathway involves activation of caspase. Medical search. Frequent questions

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Anatomy24

Mitochondria Jurkat Cells Cell Line, Tumor Cell Line Tumor Cells, Cultured Cells, Cultured HL-60 Cells HeLa Cells Cytosol U937 Cells Mitochondrial Membranes Neurons Cell Nucleus Intracellular Membranes Cell-Free System Fibroblasts Epithelial Cells Cell Line, Transformed Cytoplasm Hepatocytes Macrophages Endoplasmic Reticulum K562 Cells T-Lymphocytes

Organisms5

Mice, Inbred C57BL Mice, Knockout Rats, Sprague-Dawley Drosophila Mice, Transgenic

Diseases3

Necrosis Disease Models, Animal Neuroblastoma

Chemicals and Drugs119

Caspase 3 Caspase 9 Caspase Inhibitors Caspase 8 Caspase 7 Caspases Caspase 1 Caspase 10 Amino Acid Chloromethyl Ketones Cysteine Proteinase Inhibitors Caspase 12 Caspase 14 Proto-Oncogene Proteins c-bcl-2 Cytochromes c Antigens, CD95 Cytochrome c Group X-Linked Inhibitor of Apoptosis Protein Poly(ADP-ribose) Polymerases Apoptotic Protease-Activating Factor 1 bcl-2-Associated X Protein Inhibitor of Apoptosis Proteins Caspases, Initiator BH3 Interacting Domain Death Agonist Protein Apoptosis Regulatory Proteins Cysteine Endopeptidases Oligopeptides Fas-Associated Death Domain Protein Enzyme Inhibitors bcl-X Protein Apoptosis Inducing Factor CASP8 and FADD-Like Apoptosis Regulating Protein Staurosporine Annexin A5 Carrier Proteins TNF-Related Apoptosis-Inducing Ligand Enzyme Precursors Caspases, Effector Apoptosomes Reactive Oxygen Species Tumor Necrosis Factor-alpha Proteins CRADD Signaling Adaptor Protein Intracellular Signaling Peptides and Proteins Antineoplastic Agents Death Domain Receptor Signaling Adaptor Proteins Phosphatidylserines CARD Signaling Adaptor Proteins bcl-2 Homologous Antagonist-Killer Protein Calpain Granzymes Proto-Oncogene Proteins Mitochondrial Proteins Tumor Suppressor Protein p53 Receptor-Interacting Protein Serine-Threonine Kinases Antineoplastic Agents, Phytogenic RNA, Small Interfering Receptors, Tumor Necrosis Factor Receptors, TNF-Related Apoptosis-Inducing Ligand Membrane Glycoproteins bcl-Associated Death Protein NF-kappa B Serpins JNK Mitogen-Activated Protein Kinases Etoposide Adaptor Proteins, Signal Transducing Recombinant Proteins Ceramides Receptor-Interacting Protein Serine-Threonine Kinase 2 Protein Synthesis Inhibitors Myeloid Cell Leukemia Sequence 1 Protein Drosophila Proteins Neoplasm Proteins Protein-Serine-Threonine Kinases Coumarins RNA, Messenger Mitogen-Activated Protein Kinases Propidium Receptors, Death Domain Proto-Oncogene Proteins c-akt Cycloheximide Membrane Proteins Protease Inhibitors Nucleic Acid Synthesis Inhibitors Receptors, Tumor Necrosis Factor, Type I p38 Mitogen-Activated Protein Kinases Serine Endopeptidases Acetylcysteine Proteasome Endopeptidase Complex Viral Proteins Hydrogen Peroxide Cell Extracts Recombinant Fusion Proteins Deoxyadenine Nucleotides Neuroprotective Agents Lamins Insect Proteins Microtubule-Associated Proteins DNA Primers Nuclear Proteins Interleukin-1beta Flavoproteins Cathepsin B Bongkrekic Acid Pentanoic Acids Doxorubicin Aspartic Acid L-Lactate Dehydrogenase Protein Kinase C-delta Lamin Type B Isatin Keratin-18 Glutathione Leupeptins Mitogen-Activated Protein Kinase 8 Fluorescent Dyes Proteasome Inhibitors Green Fluorescent Proteins Peptide Fragments Culture Media, Serum-Free

Analytical, Diagnostic and Therapeutic Techniques and Equipment15

In Situ Nick-End Labeling Blotting, Western Transfection Flow Cytometry Models, Biological Immunoblotting Reverse Transcriptase Polymerase Chain Reaction Microscopy, Fluorescence Immunohistochemistry Drug Screening Assays, Antitumor Disease Models, Animal Microscopy, Confocal Gene Knockdown Techniques Xenograft Model Antitumor Assays Culture Media, Serum-Free

Phenomena and Processes46

Apoptosis Enzyme Activation DNA Fragmentation Cell Death Cell Survival Signal Transduction Membrane Potential, Mitochondrial Necrosis Transfection Dose-Response Relationship, Drug Time Factors Amino Acid Sequence Cell Proliferation Genes, bcl-2 Down-Regulation Protein Structure, Tertiary Cell Cycle Phosphorylation Drug Synergism Mutation Up-Regulation Substrate Specificity Membrane Potentials Autophagy RNA Interference Protein Processing, Post-Translational Oxidative Stress Protein Binding Proteolysis Protein Transport DNA Damage Hydrolysis Ultraviolet Rays Drug Resistance, Neoplasm Gene Expression Regulation Gene Expression Endoplasmic Reticulum Stress Cell Division Sequence Homology, Amino Acid Gene Expression Regulation, Neoplastic Permeability Cell Differentiation Cytoprotection Gene Expression Regulation, Enzymologic MAP Kinase Signaling System Binding Sites

Disciplines and Occupations1

Immunohistochemistry

Information Science2

Amino Acid Sequence Molecular Sequence Data

Health Care1

Ultraviolet Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Caspase 3 Caspase 9 Caspase Inhibitors Caspase 8 Caspase 7 Caspases Caspase 1 Caspase 10 Apoptosis Amino Acid Chloromethyl Ketones Cysteine Proteinase Inhibitors Caspase 12 Caspase 14 Enzyme Activation DNA Fragmentation Proto-Oncogene Proteins c-bcl-2 Cytochromes c Mitochondria Antigens, CD95 Cytochrome c Group X-Linked Inhibitor of Apoptosis Protein Poly(ADP-ribose) Polymerases Apoptotic Protease-Activating Factor 1 bcl-2-Associated X Protein Cell Death Inhibitor of Apoptosis Proteins Jurkat Cells Caspases, Initiator In Situ Nick-End Labeling Cell Survival BH3 Interacting Domain Death Agonist Protein Apoptosis Regulatory Proteins Signal Transduction Cell Line, Tumor Cysteine Endopeptidases Oligopeptides Fas-Associated Death Domain Protein Enzyme Inhibitors Cell Line bcl-X Protein Apoptosis Inducing Factor Blotting, Western Tumor Cells, Cultured Cells, Cultured CASP8 and FADD-Like Apoptosis Regulating Protein Staurosporine Annexin A5 Membrane Potential, Mitochondrial Carrier Proteins HL-60 Cells TNF-Related Apoptosis-Inducing Ligand Enzyme Precursors HeLa Cells Necrosis Caspases, Effector Apoptosomes Reactive Oxygen Species Tumor Necrosis Factor-alpha Transfection Proteins CRADD Signaling Adaptor Protein Intracellular Signaling Peptides and Proteins Antineoplastic Agents Death Domain Receptor Signaling Adaptor Proteins Dose-Response Relationship, Drug Flow Cytometry Phosphatidylserines CARD Signaling Adaptor Proteins bcl-2 Homologous Antagonist-Killer Protein Calpain Granzymes Time Factors Proto-Oncogene Proteins Mitochondrial Proteins Tumor Suppressor Protein p53 Receptor-Interacting Protein Serine-Threonine Kinases Antineoplastic Agents, Phytogenic RNA, Small Interfering Amino Acid Sequence Receptors, Tumor Necrosis Factor Receptors, TNF-Related Apoptosis-Inducing Ligand Cell Proliferation Membrane Glycoproteins Cytosol bcl-Associated Death Protein Molecular Sequence Data NF-kappa B Serpins JNK Mitogen-Activated Protein Kinases Etoposide U937 Cells Genes, bcl-2 Adaptor Proteins, Signal Transducing Mitochondrial Membranes Recombinant Proteins Models, Biological Down-Regulation Mice, Inbred C57BL Ceramides Immunoblotting

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