• To examine the T(2)-normal appearing spinal cord of patients with multiple sclerosis (MS) using diffusion tensor imaging. (nih.gov)
  • In 1877, Althaus unsuccessfully tried to rename the disease multiple sclerosis "Charcot's disease" after the disease's first descriptor, Jean-Martin Charcot. (wikipedia.org)
  • Multiple Sclerosis: The History of a Disease. (wikipedia.org)
  • Our primary research focus is multiple sclerosis (MS), an inflammatory demyelinating disease of the brain and spinal cord. (ucl.ac.uk)
  • Diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), and Multiple Sclerosis (MS) affect millions of individuals in the US at a cost of hundreds of billions of dollars annually. (scientificarchives.com)
  • This blog entry reports on recent research which documents the importance of glial pathology as a general underlying factor in essentially all age related neurodegenerative diseases including Alzheimer's Disease, Parkinson's Disease, advanced spinal degeneration, ALS, multiple sclerosis, and several retinal diseases. (anti-agingfirewalls.com)
  • All neurological pathologies including like Stroke, Post Concussion, Spinal Cord Injury, Parkinson's Disease and Multiple Sclerosis. (funcphysio.jp)
  • Her research focuses on biomarker discovery and B cell analysis in neurologic and autoimmune diseases such as autism spectrum disorder, multiple sclerosis, spinal cord injury, rheumatoid arthritis and axial spondyloarthritis. (sfari.org)
  • The role of self-reactive B cells in spinal cord injury and age-associated B cells in immune aging and multiple sclerosis pathology and progression are also being studied. (sfari.org)
  • Diffusion tensor images of the spinal cord were acquired from 21 healthy subjects, 11 MS patients with spinal cord lesions, and 10 MS patients without spinal cord lesions on the T(2)-weighted MR images. (nih.gov)
  • It was observed that the FA, the transverse diffusivity lambda(perpendicular), and the ratio of the longitudinal and transverse diffusivities (lambda(parallel)/lambda (perpendicular)) were significantly lower in the spinal cord of MS patients with spinal cord lesions compared with the control subjects using both the ROI method (P = 0.014, P = 0.028, and P = 0.039, respectively) and the tractography-based approach (P = 0.006, P = 0.037, and P = 0.012, respectively). (nih.gov)
  • For both image analysis methods, the FA and the lambda (parallel)/lambda (perpendicular) values were significantly different between the control group and the MS patient group without T(2) spinal cord lesions (P = 0.013). (nih.gov)
  • Our results suggest that the spinal cord may still be affected by MS, even when lesions are not detected on a conventional MR scan. (nih.gov)
  • 34062569 ) This is most closely associated with demyelinating lesions, but may also occur with other pathologies. (emcrit.org)
  • As a result of dependence upon higher brain centers, certain lesions or diseases of the brain (eg, stroke, cancer, dementia) can result in a loss of voluntary control of the normal micturition reflex as well as symptoms such as urinary urgency. (medscape.com)
  • MRI of the spine showed a spinal cord compression due to bone and epidural tumoral lesions of the posterior wall of the D1 to D5 thoracic vertebras ( Figure 1 ). (scirp.org)
  • The lesions are inflammatory , and involve the spinal cord on both sides. (bionity.com)
  • The lesions can be present anywhere in the spinal cord, though it is usually restricted to only a small portion. (bionity.com)
  • The three main conditions to be considered in the differential diagnosis are: acute spinal cord trauma, acute compressive lesions of the spinal cord such as epidural metastatic tumour, and infarction of the spinal cord, usually due to insufficiency of the anterior spinal artery . (bionity.com)
  • Metastatic Disease of the Extremity is a malignant pathologic process that is the most common cause of destructive bone lesions in the extremities of adult patients. (orthobullets.com)
  • AFM is an illness that's characterized by the sudden onset of flaccid weakness in one or more extremities and also by distinct longitudinal gray matter lesions in the spinal cord. (cdc.gov)
  • Traumatic spinal cord injury (SCI) is perhaps the most devastating orthopedic injury, and with prolonged survival being the rule, rehabilitation of these injuries has an increasingly important role. (medscape.com)
  • Furthermore, the facility will offer nursing, physical, occupational, and speech pathology treatments for adult people recovering from disorders such as stroke, brain or spinal cord injury, neurological disease, and other severe illnesses or injuries. (hospitalmanagement.net)
  • Spinal cord injuries (SCIs) can have catastrophic effects on individuals resulting in loss of physical abilities and independence. (dovepress.com)
  • New research has shown how normally helpful brain cells can turn rogue and kill off other brain cells following injury or disease.Astrocytes have long been implicated in the pathology of a range of human neurodegenerative diseases or injuries including Alzheimer's, Huntington's Parkinson's disease, brain trauma and spinal cord injury. (enn.com)
  • In some cases, the disease is presumedly caused by viral infections or vaccinations and has also been associated with spinal cord injuries, immune reactions, schistosomiasis and insufficient blood flow through spinal cord vessels. (bionity.com)
  • Neurodegenerative diseases have a profound societal impact and pose significant healthcare costs. (scientificarchives.com)
  • That same blog entry also cites publications arguing that, t o a considerable extent, aging-related neurodegenerative diseases appear to depend on the same underlying mechanisms. (anti-agingfirewalls.com)
  • Neurodegenerative diseases of the spinal cord develop mainly in the late old age, but can be congenital and progress throughout life. (doclandmed.com)
  • to Treat neurodegenerative diseases of the spinal cord must under the supervision of experienced doctors. (doclandmed.com)
  • A major differentiation or distinction to be made is a similar condition due to compression of the spinal cord in the spinal canal, due to disease of the surrounding vertebral column. (bionity.com)
  • Myelopathy can be the result of primary intrinsic disorders of the spinal cord or from secondary conditions, which result in extrinsic compression of the spinal cord. (bvsalud.org)
  • The Spinal Cord Injury Rehabilitation (SCIRehab) project , a 5-year project led by the Rocky Mountain Regional Spinal Injury System (RMRSIS) at Craig Hospital, used practice-based evidence (PBE) research to identify the rehabilitation interventions most strongly associated with positive outcomes. (medscape.com)
  • ICORD is a world leading health research centre focused on spinal cord injury. (ubc.ca)
  • From the lab-based cellular level of understanding injury to rehabilitation and recovery, our researchers are dedicated to the development and translation of more effective strategies to promote prevention, functional recovery, and improved quality of life after spinal cord injury. (ubc.ca)
  • Therefore, a sensory level to light touch may be absent unless both of these are involved (e.g., a complete injury that involves all spinal cord tracts). (emcrit.org)
  • [ 1 ] Neurogenic bladder is a term applied to urinary bladder malfunction due to neurologic dysfunction emanating from internal or external trauma, disease, or injury. (medscape.com)
  • They say that if their approach to isolating and growing the cells can be upscaled, it might some day provide the tissue needed for disorders like peripheral nerve disease, Parkinson's and spinal cord injury. (bioedge.org)
  • Hazel T, Hefferan M, Schwartz K, Yu N, Johe K, Levy M. Generation of Human Oligodendrocyte Progenitors for Treatment of Demyelinating Diseases and Spinal Cord Injury. (scientificarchives.com)
  • This unmet medical need is a primary driver for the development of therapies based on transplantation of neural stem cells that have the potential to replace cells of the central nervous system (CNS) lost to disease or injury [1]. (scientificarchives.com)
  • Similarly, spinal cord injury is typically accompanied by progressive demyelination of axons and concomitant neuronal atrophy [3]. (scientificarchives.com)
  • Similarly, recovery of locomotor function after grafting of neural stem cells (NSC) in animal models of spinal cord injury has been demonstrated to be due at least in part to myelinating oligodendrocytes [11]. (scientificarchives.com)
  • Spinal cord injury (SCI) can result in full or partial paralysis, which limits mobility-producing muscular activation. (dovepress.com)
  • Previously I have written about the roles of glia and microglia in Alzheimer's disease and in spinal cord injury. (anti-agingfirewalls.com)
  • Following traumatic spinal cord injury (SCI), one of the main concerns from cat-owners is whether their cat can recover (i.e., a "functional pet" that can walk, able to regain urinary/fecal continence). (vin.com)
  • Milos Pekny has included themes like Response to injury, Reactive Astrocyte and Disease in his Spinal cord pathology study. (research.com)
  • Spinal cord injury (SCI) is an insult to the spinal cord resulting in a change, either temporary or permanent, in the cord's normal motor, sensory, or autonomic function. (medscape.com)
  • Peripheral neuritis and increased spinal cord neurochemicals are induced in a model of repetitive motion injury with low force and repetition exposure. (cdc.gov)
  • Here, we examined whether a low repetition task with negligible force (LRNF) produces fewer tissue and behavioral pathologies than previously observed with high repetition tasks using our rat model of repetitive motion injury (RMI). (cdc.gov)
  • Each type of pathology causes significant symptoms, by different mechanisms. (ucl.ac.uk)
  • Our research aims to understand the mechanisms responsible for the disease, in order to arrest them and thereby avoid the production of symptoms even before they have started. (ucl.ac.uk)
  • The types of symptoms and their severity are dependent on the area of the spinal cord affected. (encyclopedia.com)
  • Symptom criteria include the evolution of symptoms peaking over four hours to 21 days, with symptoms clearly traceable to spinal cord dysfunction, and including muscle weakness or paralysis and sensory defects such as numbness occurring on both sides of the body. (encyclopedia.com)
  • AD pathogenesis is initially isolated to the limbic region in afflicted patients, but as the disease progresses to other neocortical areas, additional cognitive symptoms manifest and become apparent 3 . (nature.com)
  • The criteria for diagnosing AD published by the National Institute on Neurological and Communicative Disorder and Stroke and the Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA) have been widely utilized by clinicians to distinguish between the symptoms present in "probable," "possible," or "definite" AD 5 . (nature.com)
  • The symptoms and signs depend upon the level of the spinal cord involved and the extent of the involvement of the various long tracts. (bionity.com)
  • Researchers investigating VEGF-stimulated angiogenesis have found that homozygous vegf gene 'knock-in' (VEGF d/d ) mice, in which the hypoxia-response element of the promoter is disrupted, display reduced brain and spinal cord VEGF protein levels and develop unexpected symptoms that strongly resemble ALS. (rndsystems.com)
  • mice, in which the hypoxia-response element of the promoter is disrupted, display reduced brain and spinal cord VEGF protein levels and develop unexpected symptoms that strongly resemble ALS. (rndsystems.com)
  • They presented with symptoms and signs due to cord compression at the lower thoracic and lumbar vertebrae. (who.int)
  • The spinal cord is a delicate and complex structure that runs from the brain down the center of the back. (osmosis.org)
  • The disease is characterized by inflammation within the brain and spinal cord, demyelination (loss of the insulating layer of myelin from around nerve fibres), and neuronal and axonal degeneration. (ucl.ac.uk)
  • Normal voiding is essentially a spinal reflex modulated by the central nervous system (brain and spinal cord), which coordinates function of the bladder and urethra. (medscape.com)
  • The central nervous system is composed of the brain, brain stem, and the spinal cord. (medscape.com)
  • The signal transmitted by the brain is routed through 2 intermediate segments (the brainstem and the sacral spinal cord) prior to reaching the bladder. (medscape.com)
  • Acute and chronic disorders such as MS, neuromyelitis optica spectrum disorder, transverse myelitis, and optic neuritis result in progressive demyelination of nerve axons in the brain, spinal cord, or optic nerve. (scientificarchives.com)
  • Microglia are a type of glial cell that are the resident macrophages of the brain and spinal cord , and thus act as the first and main form of active immune defense in the central nervous system (CNS). (anti-agingfirewalls.com)
  • Microglia (and astrocytes , another type of glial cells) are distributed in large non-overlapping regions throughout the brain and spinal cord. (anti-agingfirewalls.com)
  • [3] The brain and spinal cord are considered "immune privileged" organs in that they are separated from the rest of the body by a series of endothelial cells known as the blood-brain barrier , which prevents most infections from reaching the vulnerable nervous tissue. (anti-agingfirewalls.com)
  • It is possible to observe neuritic plaques and neurofibrillary tangles within the brain tissue of patients afflicted by Alzheimer's disease (AD). (nature.com)
  • Neurological disorder is an umbrella term represents diseases and disorders that affect the brain and nervous system. (neuroscience.network)
  • The vital components of CNS like Brain and Spinal cord are encapsulated in copious membranes which are assailable to force and pressure. (neuroscience.network)
  • Neurosurgery is the surgical specialization that treats diseases and disorders of the brain and spinal cord. (lerraclinic.com)
  • Milos Pekny combines subjects such as Neuroglia, Astrogliosis, Microglia, Alexander disease and Brain ischemia with his study of Astrocyte. (research.com)
  • Research done in the last decade has shown that certain tumors of the brain and spinal cord, are sensitive to chemotherapy. (sciencedaily.com)
  • Myelopathy is a clinical diagnosis with localization of the neurological findings to the spinal cord, rather than the brain or the peripheral nervous system, and then to a particular segment of the spinal cord. (bvsalud.org)
  • I'm a board certified neuro-oncologist who treats both primary brain tumors as well as metastatic disease to the brain and nervous system. (stanford.edu)
  • Pathogenic infections of the brain, spinal cord, and meninges. (bvsalud.org)
  • It is a clear, colorless fluid that flows in and around your brain and spinal cord. (medlineplus.gov)
  • Your brain and spinal cord make up your central nervous system. (medlineplus.gov)
  • Introduction to the Neurologic Examination The purpose of the neurologic examination is to establish whether the patient's brain, special senses, spinal cord, peripheral nerves, and muscle and skin receptors are functioning normally. (msdmanuals.com)
  • There is wide agreement that excessive microglial activation is a key process in nervous system disorders involving release of strong pro-inflammatory cytokines, cytokines which can trigger worsening of multiple disease states. (anti-agingfirewalls.com)
  • Diseases of the endocrine system (complications of diabetes, diffuse toxic goiter, etc. (azimuthotels.com)
  • Despite the extensive research dedicated to deciphering AD pathogenesis and discovering novel drug treatments, the comorbid nature of this disease, along with other psychological and physiological complications, obstructs the ability to examine the therapeutic effectiveness of these methods. (nature.com)
  • Drug therapy is aimed at stopping the progression of the disease and prevention of complications. (doclandmed.com)
  • Note that the spinal cord level doesn't line up precisely with the corresponding vertebrae, especially caudal to the thoracic spine. (emcrit.org)
  • Lhermitte's sign (an electric-shock sensation elicited by neck flexion that runs down the spine and sometimes into the limbs) suggests involvement of the posterior columns of the cervical spinal cord. (emcrit.org)
  • We report a rare case of adult Langerhans cell histiocytosis in the dorsal spine causing a spinal cord compression associated with a pulmonary process treated by surgery, radiotherapy and systemic therapy with good evolution. (scirp.org)
  • Final diagnosis was therefore Langerhans cell histiocytosis of the dorsal spine complicated by spinal cord compression. (scirp.org)
  • Medical center, Uridyl is a network of clinics specializing in the treatment of diseases of the spine and joints. (doclandmed.com)
  • Spinal hospital Uridyl (Wooridul) one of the leading centers for the treatment of spine diseases on the planet. (doclandmed.com)
  • Subsequently, polytomography was used in conjunction with air myelography, and exquisite images of the spinal cord were obtained. (ajnr.org)
  • The presence of a spinal cord tumor or another condition that is exerting pressure on the spinal cord, vitamin B12 deficiency, or a history of radiation therapy to or cyclophosphamide injection into the spinal cord excludes the possibility of a diagnosis of transverse myelitis. (encyclopedia.com)
  • Distribution of diseases included equine cervical vertebral stenotic myelopathy (n=224), fracture/subluxation (n=123), abnormal spinal curvature (n=51), osteomyelitis (n=13), intervertebral disc disease (n=7), congenital vertebral anomaly (n=5), and neoplasia (n=3). (thehorse.com)
  • Vertebral pathology associated with equine cervical vertebral stenotic myelopathy ( wobbler syndrome ) comprised the majority of cases. (thehorse.com)
  • Moreover, spinal involvement causing myelopathy is even rare and unusual. (scirp.org)
  • The present study looked at samples from six patients with sickle cell disease who were undergoing gene therapy as part of a major clinical trial at Boston Children's Hospital. (press-news.org)
  • Current technological advancements in clinical and research settings have permitted a more intensive and comprehensive understanding of Alzheimer's disease (AD). (nature.com)
  • This paper describes the clinical manifestations, diagnosis and management of schistosomiasis of the spinal cord in 5 patients attending Shaab and Ibn Khuldoun Hospitals, Khartoum from 1997 to 2007. (who.int)
  • Currently, more than 2 billion people (ie, one third of the world's population) are infected with tuberculosis (TB), 10% of whom develop clinical disease, and 1.4 million of whom die of the disease annually. (medscape.com)
  • Some of his works include: A treatise on medical electricity, theoretical and practical, and its use in the treatment of paralysis, neuralgia, and other diseases, 1859. (wikipedia.org)
  • On infantile paralysis and some allied diseases of the spinal cord: their diagnosis and treatment, 1878. (wikipedia.org)
  • Thus, diseases affecting the anterior horn of the spinal cord cause flaccid paralysis. (emcrit.org)
  • Transverse myelitis is an inflammation of the full width of the spinal cord that disrupts communication to the muscles, resulting in pain , weakness, and muscle paralysis. (encyclopedia.com)
  • Because of the acuteness of this lesion, signs of spinal shock may be evident, in which the lower limbs will be flaccid and areflexic, rather than spastic and hyperreflexic as they should be in upper motor neuron paralysis. (bionity.com)
  • Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is characterized by a progressive degeneration of spinal cord and cerebral cortex motor neurons, leading to muscular atrophy, paralysis, respiratory failure, and death. (rndsystems.com)
  • As a result of these developments, enthusiasm for the potential of VEGF as a therapeutic target Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is characterized by a progressive degeneration of spinal cord and cerebral cortex motor neurons, leading to muscular atrophy, paralysis, respiratory failure, and death. (rndsystems.com)
  • The first step towards diagnosis and therapy is recognizing that the patient has some sort of spinal cord pathology. (emcrit.org)
  • Diagnosis involves meeting specific symptom criteria, as well as demonstrating spinal cord involvement with MRI scanning and examination of cerebrospinal fluid. (encyclopedia.com)
  • Since the outcome of SCC is primarily determined by the patient's neurological status at treatment initiation, the goal must be to establish the underlying diagnosis before development of irreversible spinal cord damage. (sajch.org.za)
  • Due to the long prodromal period of AD, the potential for early diagnosis of AD is crucial to effectively utilize disease-modifying drugs. (nature.com)
  • Current projects focus on predictive biomarkers for autism spectrum disorder and novel biomarkers for diagnosis, prognosis and therapy response in rheumatic diseases. (sfari.org)
  • Thus, performance of even a low repetition, negligible force upper extremity task for 3 months can induce mild peripheral tissue inflammation, neurochemical increases in spinal cord dorsal horns, and declines in fine motor control. (cdc.gov)
  • Evaluating for a sensory level using a pin to detect pain sensation is more sensitive to detect a spinal level originating from a lesion in the spinothalamic tract. (emcrit.org)
  • Motor weakness may be used to evaluate the level of a spinal lesion that involves the corticospinal tract. (emcrit.org)
  • Thus, a central spinal cord lesion may cause neurologic deficits in a descending order. (emcrit.org)
  • An SCI results in a complex series of events that include a lesion within the spinal cord, glial scarring around the lesion, release of chemicals that inhibit axonal growth in the damaged area, and axonal demyelination of nearby but initially unaffected neurons. (dovepress.com)
  • A lesion of the thoracic spinal cord (T1-12) will produce a spastic paraplegia. (bionity.com)
  • A lesion of the lower part of the spinal cord (L1-S5) often produces a combination of upper and lower motor neuron signs in the lower limbs. (bionity.com)
  • Wobbler syndrome occurs when malformation of the cervical vertebrae results in spinal canal narrowing and cervical spinal cord compression. (thehorse.com)
  • Journal of Alzheimer's Disease. (elsevierpure.com)
  • One century after its first description, pathology of Alzheimer's disease (AD) is still poorly understood. (frontiersin.org)
  • Alzheimer's disease (AD) is a pervasive neurological disorder, which is irreversible, progressive, and incurable at present. (frontiersin.org)
  • In my February 2010 blog entry New views of Alzheimer's disease and new approaches to treating it , I cited evidence for the hypothesis that microglial cell senescence is probably a fundamental cause for AD, a cause upstream of beta amyloid plaque production and the setting in of tau tangles. (anti-agingfirewalls.com)
  • In the March 2011 blog entry Alzheimer's Disease Update I included a discussion on this hypothesis and on how with aging microglia lose their capability to get rid of beta amyloid via phagocytosis. (anti-agingfirewalls.com)
  • Grey matter is found within the medial portion of the spinal cord and has two dorsal or posterior horns that contain cell bodies of sensory neurons and two ventral or anterior horns that contain cell bodies of motor neurons. (osmosis.org)
  • For this to happen, a first order neuron, found inside a dorsal root ganglion carries sensory input from the skin to the dorsal horn of the spinal cord , where it synapses with the second order neuron. (osmosis.org)
  • Examination of spinal cord dorsal horns revealed increased immunoexpression of Substance P in week 8 and neurokinin-1 in weeks 8 and 12 in the superficial lamina. (cdc.gov)
  • Urological diseases (sexual dysfunction). (azimuthotels.com)
  • EIAV lentiviral vector delivery of the human VEGF gene to the gastrocnemius muscle of an ALS-like SOD1 G93A -mutant mouse elicits stable expression of VEGF in the spinal cord, thereby preventing motor neuron death, delaying disease onset, reducing motor dysfunction, and increasing life expectancy. (rndsystems.com)
  • ABSTRACT Schistosomiasis of the spinal cord is an uncommon but potentially curable form of schistosomiasis, if diagnosed and managed early. (who.int)
  • Preoperative, operative and postoperative radiological examinations and operative notes of 31 patients with spinal arachnoid cyst operated on during 2002-2009 at the Institute of Medical Sciences, Banaras Hindu University, were evaluated. (nih.gov)
  • Transverse myelitis is a neurological disorder caused by an inflammatory process of the grey and white matter of the spinal cord, and can cause axonal demyelination. (bionity.com)
  • The cord showed demyelination near the ova and an associated inflammatory reaction. (who.int)
  • High levels of IgG may mean you have an infection or an inflammatory or autoimmune disease that involves your central nervous system. (medlineplus.gov)
  • A significant original observation was made in 1903 when Froin demonstrated that after a lumbar puncture, xanthochromatic changes within the CSF, and its massive coagulation, pointed to spinal compression (1) . (ajnr.org)
  • In the first version, one of Sicard's pupils injected lipiodol into the lumbar muscles and, when he drew back the plunger of the syringe, noticed to his horror that he was withdrawing spinal fluid. (ajnr.org)
  • To get a sample of cerebrospinal fluid, a provider will do a procedure called a spinal tap, also known as a lumbar puncture. (medlineplus.gov)
  • As technology associated with advanced imaging and diagnostic modalities progresses, more attention is being given to equine vertebral column pathology. (thehorse.com)
  • The vertebral column serves important roles in protection of the spinal cord and locomotion. (thehorse.com)
  • Therefore, diseases that impact the vertebral column can have a significant impact on equine health and rider safety. (thehorse.com)
  • Equine submissions to the University of Kentucky Veterinary Diagnostic Laboratory over a 10-year period (2011-2021) were queried for diagnoses related to significant vertebral column pathology. (thehorse.com)
  • Expanded neural progenitors derived from regions of human fetal forebrain have been shown to have significant capacity to remyelinate rodent spinal cord upon grafting into areas of focal demyelination [9], and can myelinate host axons in a mouse model Pelizaeus-Merzbacher disease, which is characterized by severe hypomyelination [10]. (scientificarchives.com)
  • the main pathology is caused history of travel to schistosomiasis- of 3 patients showed swelling of the by a granulomatous inflammation endemic areas, imaging and laboratory spinal cord at D12 to L1 or L2 with around eggs trapped in the tissues [2,3]. (who.int)
  • Amyotrophic lateral sclerosis (ALS) is a devastating degenerative disease characterized by progressive loss of motor neurons in the motor cortex, brainstem, and spinal cord. (jci.org)
  • The secondary neuron then ascends up the length of the spinal cord via the spinothalamic tracts , and eventually synapse with a 3rd order neuron located in the ventral posterior nucleus of the thalamus . (osmosis.org)
  • His study in Astrocyte is interdisciplinary in nature, drawing from both Spinal cord pathology, Hippocampus and Neural stem cell. (research.com)
  • The findings illustrate a form of neural plasticity based in myelin, and future work on the molecular mechanisms responsible may ultimately shed light on a broad range of neurological and psychiatric diseases," said Monje, senior author of the paper. (stanford.edu)
  • Laryngology and speech pathology specialists will provide you with a comprehensive evaluation of swallowing function during your first visit. (sutterhealth.org)
  • 2 In light of other evidence supporting a role for VEGF in neuroprotective mechanisms, 3 these data implicate a failure of VEGF neuroprotection in the molecular pathology of ALS. (rndsystems.com)
  • this group of diseases include Friedreich's ataxia, hereditary spastic paraplegia, cerebellar ataxia, amyotrophic lateral sclerosis. (doclandmed.com)
  • He conducted early electrical treatment of patients at King's College Hospital and he was mainly instrumental in creating the Maida Vale Hospital for Nervous Diseases. (wikipedia.org)
  • This facility in Regent's Park later became the Maida Vale Hospital for Nervous Diseases and it is now part of National Hospital for Neurology and Neurosurgery. (wikipedia.org)
  • A second major line of research concerns cerebral small vessel disease, which becomes common with ageing, and is a major cause of strokes and dementia. (ucl.ac.uk)
  • Also here research is carried out for the study of Hodgkin's disease, cerebral palsy and many other diseases to create new methods of treatment. (doclandmed.com)
  • 4 Baseline VEGF levels in human cerebral spinal fluid are reduced in ALS patients compared to controls. (rndsystems.com)
  • Previously, my lab found that patients with medulloblastoma or glioma tumors with higher levels of PID1 mRNA had longer survival times," said Erdreich-Epstein, principal investigator of the study and associate professor of Pediatrics and Pathology at the Keck School of Medicine of USC. (sciencedaily.com)
  • Sophia Antipolis, 3 February 2017: Number of children is emerging as a novel factor that influences the risk for some cardiovascular diseases (CVD), and in some societies in both parents, according to Professor Vera Regitz-Zagrosek, chairperson of the European Society of Cardiology "management of CVD During Pregnancy" guidelines task force. (enn.com)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • And I am representing the Clinician Outreach and Communication Activity, COCA, with the Healthcare Preparedness Activity at the Centers for Disease Control and Prevention. (cdc.gov)
  • I'm Commander Ibad Khan and I'm representing the Clinician Outreach and Communication Activity, COCA, with the Emergency Risk Communication Branch at the Centers for Disease Control and Prevention. (cdc.gov)
  • Dr. Janell Routh is a medical officer on the acute flaccid myelitis team at the Centers for Disease Control and Prevention. (cdc.gov)
  • Adriana Lopez is an epidemiologist on the acute flaccid myelitis team at the Centers for Disease Control and Prevention. (cdc.gov)
  • Finally, Dr. Manisha Patel is the acute flaccid myelitis team lead at the Centers for Disease Control and Prevention. (cdc.gov)
  • The rehabilitation team functions under the direction of a physiatrist (ie, a physician who specializes in physical medicine and rehabilitation) or a physician with a subspecialty certification in spinal cord medicine. (medscape.com)
  • Spinal cord disease in children with known or suspected malignancy is an oncological emergency because it commonly implies malignant spinal cord compression (SCC). (sajch.org.za)
  • In general, any SCI patient presented with paraplegia/tetraplegia without deep pain perception (DPP), the prognosis for functional recovery is guarded as the "spinal cord function" is completely blocked or transected at the injured site. (vin.com)
  • A thorough neurological examination is fundamental to evaluate the spinal cord function and provide the client with a reasonable prognosis. (vin.com)
  • Our first presenter, Dr. Feikin is Chief of the Epidemiology Branch in the Division of Viral Diseases, National Center for Immunization and Respiratory Diseases at CDC. (cdc.gov)
  • Patients with partial cord involvement may fail to display a sensory level. (emcrit.org)
  • The degree and type of sensory loss will depend upon the extent of the involvement of the various sensory tracts, but there is often a "sensory level" (at the sensory segmental level of the spinal cord below which sensation to pin or light touch is impaired). (bionity.com)
  • and PRION DISEASES may involve the central nervous system as a primary or secondary process. (bvsalud.org)
  • Guillain-Barre Syndrome is a severe disease that affects the polarity of the immune system. (vsebolezni.com)
  • Spinal nerves and corresponding sensory dermatomes are shown above. (emcrit.org)
  • Considerable pain often occurs in the back, extending laterally to involve the sensory distribution of the diseased spinal segments-so-called "radicular pain. (bionity.com)
  • Ten years later, Pierre Marie, Foix, and Robert pointed out the value of serial punctures at different levels of the spinal canal. (ajnr.org)
  • None had hepato- japonicum live in the mesenteric vascular somiasis of the spinal cord. (who.int)
  • Diseases of the nervous system, their prevalence and pathology, 1877. (wikipedia.org)
  • He has a broad infectious disease experience in bacterial and viral infectious diseases including vaccine preventable diseases. (cdc.gov)