PANCREATIC DUCTAL ADENOCARCINOMA CLINICAL FEATURES Ductal adenocarcinoma of the pancreas is the most common malignant neoplasm of the pancreas. (coek.info)
Mucinous1
Although pancreatic cysts are heterogeneous, they can be clustered into the larger groups of pseudocysts (PC), and serous and mucinous pancreatic cystic neoplasms (S-PCN and M-PCN, respectively). (bvsalud.org)
Although understanding of the molecular features underlying pancreatic neoplasms is still in its infancy, a strong emphasis on the relevance of these findings for the practicing surgical pathologist is provided. (coek.info)
INTRODUCTION Pancreatic cancer is the fourth leading cause of cancer death in both men and women in the United States.1 There have been significant advances in our understanding of the genetics of pancreatic neoplasms in the past 2 decades, as well as an explosion of information over the past 3 years, largely because of the availability of whole genome and exome sequencing technologies. (coek.info)
This article provides a state-of-the-art review of the molecular genetics of pancreatic neoplasms with a strong emphasis on the relevance of these findings for the practicing surgical pathologist. (coek.info)
Pancreas1
Yilmaz & Deshpande occasionally, they are cystic and thus can mimic primary cystic neoplasms of the pancreas. (coek.info)
Histologically1
The neoplasms may be histologically the same or different, and may be found in the same or different sites. (lookformedical.com)
Poorly differentiated1
It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
Tumors1
A small proportion of these tumors show large ducts lined by neoplastic cells, the so-called large-duct variant of adenocarcinoma. (coek.info)
Malignancy1
Rectal cancer is a common malignancy of the gastrointestinal tract. (bvsalud.org)
Invasion1
Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. (lookformedical.com)
Epithelial3
Immunohistochemical stain for CK7 highlighted the epithelial lining of the cystic spaces with weak, patchy labeling for inhibin (Figures 3 and 4). (pbpath.org)
The epithelial neoplasms have occurred in older dogs compared to those of other histogenic origins (mesenchymal and other origins/round cells). (bvsalud.org)
This study aimed to quantify nasosinusal neoplasms diagnosed in dogs in 20 years (2000-2019) and characterize the main clinical, macroscopic, and histological aspects of these neoplasms. (bvsalud.org)
The main clinical signs were similar between the histogenetic categories, related to the involvement of the upper respiratory tract, sometimes accompanied by nervous signs (when there was brain invasion of nasal neoplasms or vice versa). (bvsalud.org)
Through this study, it was possible to establish the frequency of these neoplasms in 20 years and their clinical, macroscopic, and histological characteristics. (bvsalud.org)
Cells2
Figure 1: Multiloculated cyst with intervening hyalinized fibrous stroma, cystic spaces are lined by cuboidal to flattened cells with clear cytoplasm, without nuclear atypia. (pbpath.org)
Examination on higher magnification demonstrated focal areas of small glandular/cystic spaces lined by single layer of bland, cuboidal to flattened cells with uniform nuclei and clear cytoplasm similar to those present the resection specimen (Figure 7). (pbpath.org)
Main1
EUS and CT scan showed a multilobulated cystic lesion (2.5 cm) with a solid component, not in communication with the main pancreatic duct. (pbpath.org)