• Many bacteria enter the viable but non-culturable (VBNC) state to maximize resources and increase their tolerance to harmful conditions to cope with environmental stress, which has been described for a plethora of important human and foodborne pathogens. (frontiersin.org)
  • REPJFX01 is a persistent, multidrug-resistant strain of Salmonella Infantis bacteria that has caused illnesses and outbreaks in the United States and globally. (cdc.gov)
  • Bacteria in the strain are within 82 allele differences of one another by core genome multilocus sequence typing (cgMLST) . (cdc.gov)
  • CDC uses "persistent" to describe some strains of bacteria that have caused illness for years. (cdc.gov)
  • Oral and respiratory tract infections caused by bacteria such as Streptococcus pneumoniae and Klebsiella pneumoniae pose a particular threat because of the rise of antibiotic-resistant strains, with vulnerable patient populations at high risk of infection [ 2 , 3 ]. (springer.com)
  • Complete genome of the cotton bacteria blight pathogen Xanthomonas citri pv. (usda.gov)
  • Bacteria are extremely efficient at increasing resistance, not only by rapid multiplication of a single resistant strain but also by dissemination of resistance genes among strains of the same or different species. (who.int)
  • Bacteria evolve quickly, duplicating themselves orders of magnitude faster than we can reproduce and making multitudes of new mutant strains," said study co-lead author Nicole Haloupek, a Ph.D. student in Nogales' lab. (lbl.gov)
  • Instead, we found that some patients could generate cross-opsonic antibodies, leading to phagocytosis of bacteria across strains. (lu.se)
  • The antimicrobial activity displayed by some lactic acid bacteria isolates suggests the possibility of its use against pathogens , and they might be effective as a barrier in these microorganisms development and as biological preservatives in coalho cheese. (bvsalud.org)
  • Among food-borne pathogens, some strains could be resistant to hydrostatic pressure treatment. (metu.edu.tr)
  • This shows that strains of food-borne pathogens differ in resistance to hydrostatic pressure (345 MPa) at 25 degrees C, but this difference is greatly reduced at 50 degrees C. Pressurization at 50 degrees C, in place of 25 degrees C, will ensure greater safety of foods. (metu.edu.tr)
  • The objectives of the present investigation were to study the antagonistic action of probiotic microorganisms against selected food-borne pathogens and to elucidate the mechanism of such action. (scialert.net)
  • The antibiotics are released in the presence of Salmonella , which is known to produce H 2 S. This approach prevents the quick absorption of antibiotics into the bloodstream, allows localized targeting of the pathogen in the gut, and alleviates disease symptoms in a mouse infection model. (nature.com)
  • This strain of Salmonella Infantis is relatively diverse genetically. (cdc.gov)
  • CDC and local, state, and federal health and regulatory partners have investigated several clusters of Salmonella Infantis illness as possible outbreaks caused by the REPJFX01 strain. (cdc.gov)
  • Salmonella typhimurium is an economically important pathogen of humans and animals. (usda.gov)
  • Recently, Salmonella strains have arisen that are resistant to multiple antimicrobials including third generation cephalosporins. (usda.gov)
  • Additionally, a sensitive Salmonella strain can survive and transmit efficiently between animals even with antimicrobial selective pressure at MIC levels. (usda.gov)
  • Resistencia a múltiples antibióticos en serovariedades de Salmonella aisladas de muestra. (bvsalud.org)
  • Salmonella enterica es un patógeno transmitido por alimentos y agente etiológico de brotes alimentarios de gran impacto en la salud humana. (bvsalud.org)
  • El objetivo de este trabajo fue generar información sobre los serotipos circulantes, resistencia a los antibióticos y presencia de resistencia simultánea a múltiples fármacos en Salmonella provenientes de muestras clínicas humanas y muestras de alimentos en el periodo desde 2017 a 2019. (bvsalud.org)
  • Fueron analizadas un total de 668 cepas de Salmonella aisladas en los años 2017, 2018 y 2019 a partir de muestras clínicas humanas y de alimentos, en el Laboratorio Central de Salud Pública y/o remitidas por Laboratorios de la Red de Enteropatógenos. (bvsalud.org)
  • Salmonella enterica is a foodborne pathogen and etiological agent of food outbreaks with a great impact on human health. (bvsalud.org)
  • A total of 668 Salmonella strains isolated in the years 2017, 2018 and 2019 were analyzed from human and food clinical samples, at the Central Public Health Laboratory and / or sent by Laboratories of the Enteropathogens Network. (bvsalud.org)
  • A comparison of four virulent Y. pestis strains with the human-avirulent strain 91001 provides further insight into the genetic basis of virulence to humans. (asm.org)
  • Studies have confirmed that the cagA -positive strains are more virulent than the cagA -negative strains and can cause more severe gastric inflammation [ 5 ]. (biomedcentral.com)
  • These data emphasize the need for further research regarding the characteristics of bacterial pathogens in the VBNC state and present the advantages and high-throughput capabilities of ATP determinations to investigate tolerance of VBNC pathogens to antimicrobials. (frontiersin.org)
  • The presented method should be helpful in order to identify appropriate countermeasures, treatments, or disinfectants when confronted with bacterial pathogens in the VBNC state. (frontiersin.org)
  • Nevertheless, these facilities possess unique collections of pathogenic bacterial, fungal, and viral strains and their staffs include scientists and technicians who are highly knowledgeable about the biological and epidemiological characteristics of some of the world's deadliest pathogens. (nti.org)
  • therefore, the current study was designed to assess the efficacy of certain antibiotics, toothpaste, and medicinal plant extracts ( Ajuga bracteosa and Curcuma longa ) versus the bacterial pathogens isolated from the human oral cavity. (scielo.br)
  • Among all the bacterial species, Staphylococcus aureus (29.62%) and Proteus mirabilis (22.2%) were found to be more prevalent oral pathogens. (scielo.br)
  • The data obtained through this study revealed that antibiotics were more effective for oral bacterial pathogens than toothpaste and plant extracts which showed moderate and low activity, respectively. (scielo.br)
  • The degree of disease is dependent on the bacterial strain and host factors. (lu.se)
  • Simbona UVC can disinfect bacterial, viral, and fungal pathogens from the area of 30 -120 Square meters in less than 10 minutes without chemical and it avoids pollution and other harmful effects of chemicals. (who.int)
  • The intensive use of antimicrobials for prophylaxis and treatment makes hospitals a prime site for the emergence and spread of resistant pathogens. (who.int)
  • Strain 8382s was pansensitive to all antimicrobials. (usda.gov)
  • In January 2021, the Department of Internal pathogens characterized as strong biofilm producers that Medicine - Infectious Disease and Infection Prevention are resistant to most antimicrobials. (who.int)
  • Pathogens;11(7)2022 Jun 30. (bvsalud.org)
  • Nigéria, en décembre 2022 et publie depuis lors des rapports mensuels. (who.int)
  • In accord with the principles of One Health, NARMS is expanding its testing to include environmental water samples through a collaboration with the U.S. Environmental Protection Agency and animal pathogens through collaborations with FDA's Veterinary Laboratory Investigation and Response Network (Vet-LIRN) and USDA's Animal and Plant Health Inspection Service (APHIS). (fda.gov)
  • Serious animal pathogens include bluetongue virus of sheep and African horse sickness virus. (medscape.com)
  • PVP-I was tested against Klebsiella pneumoniae and Streptococcus pneumoniae according to bactericidal quantitative suspension test EN13727 and against severe acute respiratory syndrome and Middle East respiratory syndrome coronaviruses (SARS-CoV and MERS-CoV), rotavirus strain Wa and influenza virus A subtype H1N1 according to virucidal quantitative suspension test EN14476. (springer.com)
  • The human pathogen Streptococcus pyogenes causes substantial morbidity and mortality. (lu.se)
  • Streptococcus pneumoniae (pneumococcus) is an asymptomatic colonizer of the nasopharynx in most individuals but can progress to a pulmonary and systemic pathogen upon influenza A virus (IAV) infection. (lu.se)
  • Here, we analyze the epidemiology and genetic structure of natural populations of an obligate fungal pathogen, Podosphaera plantaginis . (elifesciences.org)
  • Host immune systems impose natural selection on pathogen populations, which respond by evolving different antigenic signatures. (mcmaster.ca)
  • While the ecological and evolutionary benefits of outcrossing are theoretically well-supported, support for such benefits in pathogen populations are still scarce. (elifesciences.org)
  • Pathogen populations supporting coinfection also have a higher probability of surviving winter. (elifesciences.org)
  • Identifying areas and populations where pathogens have sex can help to identify when and where new strains are most likely to emerge. (elifesciences.org)
  • The Soviet Union operated a unique system to control deadly endemic diseases and to prevent the importation of exotic pathogens from other countries that could threaten human populations, livestock, and crops. (nti.org)
  • Ralstonia insidiosa is an opportunistic pathogen considered an emerging problem among clinically vulnerable populations such as those with chronic kidney disease. (who.int)
  • A highly pathogenic H5N1 strain of avian influenza, one which can be transmitted to other animals and birds, has been detected in Estonia, the Agricultural and Food Board (VTA) has announced. (err.ee)
  • The spring spread of the virus has not slowed down with the end of the spring nesting season, and outbreaks are also present in neighboring countries, particularly the highly pathogenic H5N8 and H5N1 strains, which have been detected in foxes in Holland and seals in the U.K. and Sweden. (err.ee)
  • Some are pathogenic, in the gut or the urinary tract, and a subset of those are very dangerous, such as the enterohemorrhagic O157:H7 strain. (asm.org)
  • These ExPEC isolates included 452 avian pathogenic E. coli strains from avian colibacillosis, 91 neonatal meningitis E. coli (NMEC) strains causing human neonatal meningitis, and 531 uropathogenic E. coli strains from human urinary tract infections. (unboundmedicine.com)
  • One such strain is called E. coli Nissle. (asm.org)
  • E. coli pathogens typically destroy these organoids and escape from inside, but Nissle was able to prevent this destruction and enable coexistence between the pathogen and the host cells. (asm.org)
  • O157:H7 carries a toxin-encoding phage that can infect and kill susceptible E. coli strains. (asm.org)
  • Ormsby MJ, White HL, Metcalf R, Oliver DM & Quilliam RS (2023) Clinically important E. coli strains can persist, and retain their pathogenicity, on environmental plastic and fabric waste. (stir.ac.uk)
  • Using antibiotic selection and luciferase expression for quantification, we show that clinically important strains of E. coli can survive on plastic for at least 28-days. (stir.ac.uk)
  • Antimicrobial therapy of salmonellosis is known to be associated with prolonged fecal carriage, without reducing symptom duration or severity, and may even increase the rates of long-term shedding of pathogens 8 . (nature.com)
  • This study might open up an avenue to develop pathogen-targeting antimicrobial glycovesicles to resolve enteric infections with a minimal risk of adverse outcomes. (nature.com)
  • This experiment was designed to study the transmissibility of a resistant strain (8381r) and a sensitive strain (8382s) of S. typhimurium with and without antimicrobial selective pressure, in a poultry model. (usda.gov)
  • To date, WHO has designated 4 SARS CoV-2 genotypes that meet the working definition of a VOC: i) contain mutations divergent from the Wuhan strain and ii) that the mutations impact one or more of the aspects of viral infection that have public health significance. (who.int)
  • Treatment failures lead to longer periods of infectivity, which increases the pool of infected people moving in the community, augmenting opportunities for spread of resistance and exposing the general population to the risk of infection with resistant strains. (who.int)
  • Importantly, these pathogens also retained their virulence (determined by using a Galleria mellonella model as a surrogate for human infection) and in some cases, had enhanced virulence following their recovery from the plastisphere. (stir.ac.uk)
  • Our findings question the dogma that mostly strain-specific immunity is developed after infection and add to our overall understanding of how immunity to S. pyogenes can evolve. (lu.se)
  • By separating carriage and disease into distinct steps and providing the opportunity to analyze the genetic variants of both the pathogen and the host, this S. pneumoniae/IAV co-infection model permits the detailed examination of the interactions of an important pathobiont with the host at different phases of disease progression. (lu.se)
  • The results presented here clearly demonstrate the differences between the two biovar antiqua lineages and support the notion that grouping Y. pestis strains based strictly on the classical definition of biovars (predicated upon two biochemical assays) does not accurately reflect the phylogenetic relationships within this species. (asm.org)
  • The results show that at 25 degrees C some strains of each species are more resistant to pressure than the others. (metu.edu.tr)
  • However, when one resistant and one sensitive strain from each species were pressurized at 345 MPa and 50 degrees C, the population of all except the resistant, aureus strain was reduced by more than 8 log cycles within 5 min. (metu.edu.tr)
  • This knowledge sheds light on the potential of these mAbs to be effective against a broad range of CCHF viral strains. (sciencedaily.com)
  • To further investigate the genomic diversity among this group and to help characterize lineages of the plague organism that have no sequenced members, we present here the genomes of two isolates of the "classical" antiqua biovar, strains Antiqua and Nepal516. (asm.org)
  • Isolates from the seasoned tofu were within one or fewer allele differences to the outbreak strain by whole genome sequencing. (medscape.com)
  • The enormous increase in international travel means that individuals exposed in one country to infections caused by resistant pathogens (e.g. those causing acute respiratory infections, cholera and other diarrhoeal diseases, gonorrhoea, malaria, typhoid fever) may introduce these into other countries where resistance can then spread. (who.int)
  • Infections with other pathogens (e.g. (thepoultrysite.com)
  • It is unclear if antibodies developed after infections with this pathogen are opsonic and if they are strain specific or more broadly protective. (lu.se)
  • It is designed to remove any micro organisms that cause hospital acquisition infections in health facilities as these infections continue to be a source of medical and economic strain in health facilities across Ethiopia and Africa. (who.int)
  • this unusual immunomodulatory response could explain the apparent high virulence of this atypical T. gondii strain. (frontiersin.org)
  • Also, the widespread occurrence of plasmids among NMEC strains and members of the mixed cluster suggests that plasmid-mediated virulence in these pathotypes warrants further attention. (unboundmedicine.com)
  • Most importantly human pathogens in the plastisphere are capable of retaining their pathogenicity. (stir.ac.uk)
  • Pasteurella ) may increase mortality, even with 'low pathogenicity' strains. (thepoultrysite.com)
  • Poorly absorbed oral antibiotics such as aminoglycosides and β-lactam families allow localized enteric targeting of pathogens 11 . (nature.com)
  • The 16.9% the strains presented multiple resistance (3 or more antibiotics) with 37 different phenotypes. (bvsalud.org)
  • Our reanalysis of previous datasets stresses the importance of following strict criteria to avoid errors in the reconstruction of ancient pathogen genomes. (eurekalert.org)
  • Further characterization of this ExPEC subset with zoonotic potential urges future studies exploring the potential for the transmission of certain ExPEC strains between humans and animals. (unboundmedicine.com)
  • VBNC pathogens can potentially present a serious risk to human health as they are invisible to routine microbiological culture-based methods. (frontiersin.org)
  • This indicates that plastics in the environment can act as reservoirs for human pathogens and could facilitate their persistence for extended periods of time. (stir.ac.uk)
  • The natural habitats and potential reservoirs of the nosocomial pathogen Acinetobacter baumannii are poorly defined. (uni-koeln.de)
  • According to the ambassador, the Russian military had found proof that US-funded "biolabs" in Ukraine were engaged in nefarious research and were enhancing dangerous pathogens. (thebulletin.org)
  • Under these conditions, possible 'leakages' of dangerous pathogens, technology, and scientific know-how from AP facilities have become threats to international security. (nti.org)
  • Here, we review reports of increased incidence of subdominant variants after vaccination campaigns and extend the current model for pathogen strain replacement, which assumes that pathogen strain replacement occurs only through the differential effectiveness of vaccines against different pathogen strains. (mcmaster.ca)
  • Wuhan strain will continue to arise, yet not all viral variants generated through mutation of the virus are important or have immediate public health relevance. (who.int)
  • 140 southern sea otters represent Type II or Type X strains, or variants of these genotypes. (frontiersin.org)
  • A probiotic can protect intestine-like cell growths from destruction by pathogens, but it can also be infected by a virus that makes it more harmful to intestinal cells! (asm.org)
  • The effect of probiotic organism on the micro ecology of the gut is to some extent dependent upon its ability to survive and preferably inhibit the proliferation of pathogens. (scialert.net)
  • In addition, various compounds produced during growth of the probiotic have been shown to inhibit the growth of pathogen such as Vibrio cholera and Bacillus cereus ( Klaenhammer, 1988 ). (scialert.net)
  • The strains Bifidobacterium breve C11 and Bifidobacterium infantis C15 used in this study were obtained from the Probiotic Laboratory Culture Collection, Universiti Putra Malaysia (UPM). (scialert.net)
  • Pathogens and antibiotic resistance patterns vary significantly among institutions and can vary within institutions over short periods (eg, month to month). (msdmanuals.com)
  • Jointly our results show that outcrossing has direct epidemiological consequences as well as a major impact on pathogen population genetic diversity, thereby providing evidence of ecological and evolutionary benefits of outcrossing in pathogens. (elifesciences.org)
  • Anthrax spores provide that ability for them to survive that process much better than other pathogens. (thebulletin.org)
  • Ash also urged to conduct coronavirus testing on travelers from the UK, Denmark and South Africa and perform genetic sequencing on their tests to examine whether the passengers have contracted the new strain. (ynetnews.com)
  • Areas where multiple strains of the fungus commonly infect the same plants result in hotspots of new genetic diversity. (elifesciences.org)
  • In addition to revealing new insights in the molecular evolution of Yersinia pestis since the Byzantine times, the new sequence shows features that could not detected due to the limitations in the coverage of a draft genome previously reported by Wagner*, including 30 newly identified mutations and structural rearrangements unique to the Justinianic strain. (eurekalert.org)
  • Vaccine-induced pathogen strain replacement: what are the mechanisms? (mcmaster.ca)
  • Detection of Brucella abortus Vaccine Strain RB51 in Water Buffalo ( Bubalus bubalis ) Milk. (bvsalud.org)
  • The isolation of B. abortus RB51 vaccine strain from a milk sample in a water buffalo farm in southern Italy emphasizes the risk to public health of consuming contaminated milk or milk products following illegal vaccination . (bvsalud.org)
  • One possible explanation is vaccine-mediated strain replacement. (cdc.gov)
  • in Hib disease to almost zero, vaccine pressure may have contributed to disease replacement by other Hi strains. (cdc.gov)
  • The Mycoplasma gallisepticum strains [wild-type S6 (208) and a vaccine-type F-K810] grown in Frey´s and Hayflick´s media were analyzed by SDS-PAGE. (scielo.br)
  • Both strains were easily differentiated on SDS-PAGE analysis by a peptide band p75, that is specific for MG F-K810 strain, used as vaccine. (scielo.br)
  • Researchers identified that an abundance of fungi in the gut, particularly strains of Candida albicans yeast, could trigger an increase in immune cells, which could worsen lung damage. (medicaldaily.com)
  • Resistant pathogens are transmitted from person to person as easily as susceptible strains. (who.int)
  • ulase-negative staphylococci (CoNS) need for a thermocycler, the speed of Approval to perform the study was and methicillin-susceptible strains has the reaction and visual read-out make obtained from the ethics committee in significant prognostic, therapeutic and LAMP a promising platform for the the Faculty of Medicine, Suez Canal economic value. (who.int)
  • In addition to its economical importance, C. graminicola is among the best characterized and most tractable fungi of the genus Colletotrichum , a genus comprising a broad range of hemibiotrophic plant pathogens that represent a constant threat to fruit and vegetable production worldwide ( http://www.broadinstitute.org ). (biomedcentral.com)
  • The threat of the unknown pathogen - highly-contagious, lethal, fast-moving - is real. (telegraph.co.uk)
  • Though both strains belong to one of the three classical biovars, they represent separate lineages defined by recent phylogenetic studies. (asm.org)
  • pathogens can win in between-strain competition by taking over individual hosts (within-host level) or by infecting more hosts (population level). (mcmaster.ca)
  • Plant Viruses As Molecular Pathogens is the only book to bring you all of this information--22 chapters--in a single volume, compiled by specialists around the globe! (routledge.com)
  • With helpful illustrations, photos, figures, models that explain viral mechanisms, and easy-to-understand reference tables, Plant Viruses As Molecular Pathogens will stimulate your thinking on this fascinating area of plant science! (routledge.com)
  • Using rhamnolipids in these types of products allows the plant to respond to threats from plant pathogens and poor nutrition in a healthy and natural way. (arbico-organics.com)
  • Plant pathogen. (atcc.org)
  • Effective hand hygiene minimises transmission of pathogens from contaminated hands of an infected individual through either direct person-to-person contact or indirectly via contamination of surfaces [ 9 , 10 ]. (springer.com)
  • Evidence from food safety investigations conducted by local public health authorities and the Canadian Food Inspection Agency (CFIA) revealed that unsanitary conditions could have led to cross-contamination of the tofu, and insufficient heating of the tofu at the production level likely resulted in failure to eliminate the pathogen. (medscape.com)
  • Based on a recent theoretical study, we suggest a broader range of possible mechanisms, some of which allow pathogen strain replacement even when vaccines are perfect -that is, they protect all vaccinated individuals completely against all pathogen strains. (mcmaster.ca)
  • Currently there are no vaccines for the other strains of Hi. (cdc.gov)
  • No vaccines are available, and our understanding of the antibody response to this human pathogen is still incomplete. (lu.se)
  • We found 453 single nucleotide polymorphisms in protein-coding regions, which were used to assess the evolutionary relationships of these Y. pestis strains. (asm.org)
  • Our research confirms that the Justinianic plague reached far beyond the historically documented affected region and provides new insights into the evolutionary history of Yersinia pestis , illustrating the potential of ancient genomic reconstructions to broaden our understanding of pathogen evolution and of historical events," said research colleague Michal Feldman. (eurekalert.org)
  • Their data also suggested that the strain was more genetically diverse than previously thought. (eurekalert.org)
  • Multilocus sequence typing at 13 loci revealed that all were infected with the same strain of T. gondii , previously characterized as an atypical and rare genotype in North America (TgCgCa1, or COUG). (frontiersin.org)
  • Respiratory pathogens such as influenza are also transmitted via airborne dispersion of small particle aerosols (≤ 5 µm) when an infected individual breathes, coughs or sneezes [ 11 ], while respiratory syncytial viruses, SARS-CoV and MERS-CoV can be spread by large droplets propelled through the air and inoculated into the eyes, nose and mouth at close range [ 12 ]. (springer.com)
  • Strain 8382s positive tissues were ICJ (31%), colon (24%), cec (69%) for tet treated and ICJ (30%), colon (30%), cec (100%) for non treated birds. (usda.gov)