The survival of P. multocida bacteria has also been shown to be increased by the addition of salt into their environments. (wikipedia.org)
Pasteurella multocida toxin (PMT), one of the virulence factors produced by the bacteria, exerts its toxicity by up-regulating various signaling cascades downstream of the heterotrimeric GTPases Gq and G12/13 in an unknown fashion. (rcsb.org)
These deaths were caused by Pasteurella multocida bacteria. (rvc.ac.uk)
The mice were injected with a vaccine against the bacteria Pasteurella multocida. (ironmagazine.com)
If your child is bitten or scratched by an animal that carries Pasteurella organisms such as Pasteurella multocida, these bacteria can enter the body through the break in the skin. (healthychildren.org)
Organism2
If P multocida is the only isolated organism, therapy may be changed to intravenous penicillin G. Once clinical improvement is noted, oral penicillin VK is an option. (medscape.com)
P. multocida is a heterogenic organism due to varied antigenic specificity. (researchsquare.com)
Infection12
Patients with a joint replacement (perhaps notably knee replacement) in place may, in particular, be at risk of secondary infection of that joint during an episode of P multocida cellulitis/bacteraemia. (wikipedia.org)
Diagnosis of the bacterium in humans was traditionally based on clinical findings, and culture and serological testing, but false negatives have been a problem due to easy death of P. multocida, and serology cannot differentiate between current infection and previous exposure. (wikipedia.org)
The duration of therapy for P multocida infection has not been well established and can be tailored to clinical response. (medscape.com)
We report a case of urinary tract infection caused by an unusual genotype (sequence type 211) of Pasteurella multocida associated with human infection. (cdc.gov)
Pulsed-field gel electrophoresis profiles of Apa I (A) and Sma I (B) digested genomic DNA of Pasteurella multocida isolates from an 83-year-old man with a urinary tract infection (lane 1) and his pet. (cdc.gov)
Infection with Pasteurella multocida is abundant in Kenya yet there is scarce information on their genetic diversity. (researchsquare.com)
Carrier or sick camels are considered as source of infection to other animals especially young calves by direct contact, on fomites, through ingesting or breathing in of the P. multocida which probably comes from the nasopharynx of infected animals [2, 6, 11, 26]. (researchsquare.com)
Pasteurella belongs to the Pasteurellaceaefamily with a wide range group of gram-negative Gamma proteobacteria.The understanding of the molecular basis of P. multocidaand the host predilection is still at a very early stage.P. multocida is a facultative pathogen.Infection with P. multocidacan cause high mortality and production decrease in cattle, pig, chicken, and rabbit farming and majoreconomic losses. (huveta.hu)
Pasteurella multocida is a gram-negative coccobacillus which is involved in a zoonotic infection. (osmosis.org)
P. multocida infection should be suspected when any local inflammation is found following an animal bite, especially when it is accompanied by evidence of involvement of distant body organs. (kitpcr.com)
PASTEURELLA MULTOCIDA is often found as a secondary infection. (bvsalud.org)
Strains5
P. multocida strains that cause fowl cholera in poultry typically belong to the serovars 1, 3, and 4. (wikipedia.org)
Strains that cause atrophic rhinitis in pigs are unique as they also have P. multocida toxin (PMT) residing on a bacteriophage. (wikipedia.org)
Other macrolides, including azithromycin, clarithromycin, and telithromycin (in order of decreasing susceptibility), retain in vitro activity against most Pasteurella strains. (medscape.com)
Pasteurella multocida toxin (PMT) is produced by native strains of Pasteurella multocida. (listlabs.com)
The hyaluronic acid (HA) capsule produced by P. multocida serogroup A strains is a critical virulence factor. (monash.edu)
Toxin7
Purified Pasteurella multocida toxin has a molecular weight of approximately 146 kDa, corresponding to 1,285 amino acids. (listlabs.com)
Pasteurella multocida toxin has been reported to also activate Rho kinase through a Gqα independent pathway. (listlabs.com)
Pasteurella multocida toxin activates the Gqα subunit that stimulates phosphatidyl-inositol-specific phospholipase C-B1. (listlabs.com)
Pasteurella multocida toxin can also stimulate Rho kinase directly by a Gqα independent pathway. (listlabs.com)
Additional intracellular events that have been demonstrated to be caused by Pasteurella multocida toxin include increase in endothelial permeability by stimulation of Rho kinase and myosin light chain phosphatase. (listlabs.com)
Pasteurella multocida toxin from List Labs is a purified native protein. (listlabs.com)
Product #156 Pasteurella multocida toxin (PMT) is provided lyophilized in Tris buffer. (listlabs.com)
Virulence factors2
P. multocida expresses a range of virulence factors including a polysaccharide capsule and the variable carbohydrate surface molecule, lipopolysaccharide (LPS). (wikipedia.org)
Now, Pasteurella multocida has a number of virulence factors, that are like assault weaponry that help it attack and destroy the host cells, and evade the immune system . (osmosis.org)
Isolates3
Antimicrobial resistance among Pasteurella isolates rarely is reported in humans. (medscape.com)
Molecular genetic analysis of P. multocida isolates obtained from the human patient and his pet strongly suggests a zoonotic transmission of this bacterium. (cdc.gov)
. Pasteurella multocida sequences were found to be highly conserved, however isolates detected in Kenya were found to be genetically related to other isolates from African and other parts of the world. (researchsquare.com)
Pneumonia4
Pasteurella multocida is common in pneumonia of cattle and pigs, and causes fowl cholera. (kitpcr.com)
Liquamycin LA-200 is indicated in the treatment of pneumonia and shipping fever complex associated with Pasteurella spp. (heartlandvetsupply.com)
A single dosage of 9 mg of Liquamycin LA-200 per lb of body weight administered subcutaneously is recommended in the treatment of the following conditions: 1) bacterial pneumonia caused by Pasteurella spp. (heartlandvetsupply.com)
Ribas , J et al "Pancoast's syndrome due to chronic pneumonia by Pasteurella multocida. (ersjournals.com)
Bacterial organisms from the Pasteurella species live in the mouths of most cats, as well as a significant number of dogs and other animals. (healthychildren.org)
Pathogens3
The tetracycline-derivative tigecycline also has excellent in vitro activity against P multocida and other pathogens encountered in animal and bite injuries. (medscape.com)
The bacterium Pasteurella multocida is one of the most frequent commensal and opportunistic pathogens found in domestic and wild animals worldwide ( 1 ). (cdc.gov)
Animal bites usually contain multiple potential pathogens, including Pasteurella multocida (particularly in cat bites), staphylococci, streptococci, and anaerobes. (msdmanuals.com)
Subsp2
Lipoprotein signal peptidase (Pasteurella multocida subsp. (nih.gov)
Regulon of PurR in Pasteurella multocida subsp. (lbl.gov)
Haemolytica1
It is common to find Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and/or Trueperella pyogenes, in addition to M. bovis, in such lesions. (uwyo.edu)
Mannheimia1
This product has been shown to be effective for the vaccination of healthy cattle three months of age or older against Infectious Bovine rhinotracheitis, Bovine Viral Diarrhea Type 1, Haemophilus Somnus, Mannheimia Haemolutica Type A-1, Mannheimia Haemolutica Type A-6, & Pasteurella Multocida Type A-3. (healthypets.com)
Bacterium3
The P. multocida serotype-1 is most associated with avian cholera in North America, but the bacterium does not linger in wetlands for extended periods of time. (wikipedia.org)
Pasteurella multocida is a Gram-negative capsulated bacterium responsible for a range of diseases that cause severe morbidity and mortality in livestock animals. (monash.edu)
It is caused by the Pasteurella multocida zoonotic bacterium. (animalresearch.info)
Cellulitis2
For example, with cellulitis caused by Pasteurella multocida , often found in animal bites, a person can have symptoms less than 24 hours after the bite. (kidshealth.org)
When appropriately treated with antibacterials, Pasteurella-related cellulitis usually clears up in about a week. (healthychildren.org)
Pathogen2
Pasteurella multocida is a highly versatile pathogen capable of causing infections in a wide range of domestic and wild animals as well as in humans and nonhuman primates. (nih.gov)
In this study, we utilized transposon-directed insertion site sequencing (TraDIS) to identify genes essential for in vitro growth of P. multocida and combined TraDIS with discontinuous density gradients (TraDISort) to identify genes required for HA capsule production and regulation in this pathogen. (monash.edu)
Pasteurellosis4
See: Pasteurellosis P. multocida causes a range of diseases in wild and domesticated animals, as well as humans. (wikipedia.org)
Pasteurella multocida is considered to be one of the normal flora in the respiratory tract of camels and other animals but it becomes pathogenic and causes pasteurellosis when the resistance of the camel body is diminished by harmful environmental influences. (researchsquare.com)
Pasteurellosis caused by Pasteurella multocida is an important disease that infect the respiratory tract of camels. (researchsquare.com)
P. multocida causes pasteurellosis when the resistance of the camel body is diminished by harmful environmental influences such as sudden changes in weather, deficiencies of dietary nutrition, long distances transportation and parasitic infestation [11]. (researchsquare.com)
Facultative2
Alright, now Pasteurella multocida is non-motile, non-spore forming, and facultative anaerobic which means it can survive in both aerobic and anaerobic environments. (osmosis.org)
Pasteurella multocida is a gram-negative, facultative anaerobic coccobacillus inhabiting the upper respiratory tract of animals, particularly in cats and dogs. (osmosis.org)
Molecular2
Despite over 135 years of research, the molecular basis for the myriad manifestations of P. multocida pathogenesis and the determinants of P. multocida phylogeny remain poorly defined. (nih.gov)
These molecular tools were applied to confirm the presence and genetic diversity of Pasteurella multocida in 102 blood and 30 nasal swab samples collected from Marsabit and Turkana counties in Kenya. (researchsquare.com)
Fowl cholera1
P. multocida is the cause of a range of diseases in mammals and birds, including fowl cholera in poultry, atrophic rhinitis in pigs, and bovine hemorrhagic septicemia in cattle and buffalo. (wikipedia.org)
Capsular3
Kmt1 gene was used as the marker gene for Pasteurella multocida and hyaD-hyaC, bcbD, dcbF, ecbJ , and fcbD as marker genes for capsular groups. (researchsquare.com)
The study confirm that the camels were infected by Pasteurella multocida of capsular type E in Marsabit and Turkana Counties of Kenya. (researchsquare.com)
Capsular polysaccharide interferes with biofilm formation by Pasteurella multocida Serogroup A. mBio. (usda.gov)
Serotype1
Mice in the V-P group showed 100 % protection after challenge with P. multocida serotype A (CQ2) at dose of 4.4 × 105 CFU (2LD50). (ironmagazine.com)
Humans1
In humans, P. multocida is the most common cause of wound infections after dog or cat bites. (wikipedia.org)
Avian2
Genome sequence of Pasteurella multocida Razi 0002 of avian origin. (pacb.com)
We report here on the genome sequence of Pasteurella multocida Razi 0002 of avian origin, isolated in Iran. (pacb.com)
Penicillin2
Pasteurella multocida is a Gram-negative, nonmotile, penicillin-sensitive coccobacillus of the family Pasteurellaceae. (wikipedia.org)
Pasteurella multocida infections are treated with antibiotics such as penicillin, tetracyclines, cephalosporins, and quinolones. (osmosis.org)
Cats1
P. multocida is commonly cultured from the oropharynx of cats and dogs, and most human infections are associated with animal exposure, mainly from cats and dogs, and usually involve soft-tissue sites after animal bites or scratches ( 1 ). (cdc.gov)
Molecule1
The LPS produced by P. multocida consists of a hydrophobic lipid A molecule (that anchors the LPS to the outer membrane), an inner core, and an outer core, both consisting of a series of sugars linked in a specific way. (wikipedia.org)
Animal2
We placed gingival swabs obtained from the animal in Amies transport medium and sent them to the hospital's clinical microbiology laboratory, where P. multocida was recovered. (cdc.gov)
A selective medium for Pasteurella multocida and its use with animal and human specimens. (bmj.com)
Found2
Pasteurella multocida was first found in 1878 in cholera-infected birds. (wikipedia.org)
DNA sequences were found to be homologous to Pasteurella multocida thereby confirming that the camels were infected by Pasteurella multocida . (researchsquare.com)
Types2
Identification of a distinct, cryptic heparosan synthase from Pasteurella multocida types A, D, and F. (ouhsc.edu)
Identification of a distinct, cryptic heparosan synthase from Pasteurella multocida types A, D, and F. J Bacteriol. (ouhsc.edu)
Retain1
Now, Pasteurella multocida has a thin peptidoglycan layer, so it doesn't retain the crystal violet dye during gram staining. (osmosis.org)
Host1
P. multocida has been observed invading and replicating inside host amoebae, causing lysis in the host. (wikipedia.org)
Blood2
P. multocida will grow at 37 °C (99 °F) on blood or chocolate agar, HS agar, but will not grow on MacConkey agar. (wikipedia.org)
Finally, Pasteurella multocida grows well at 37ºc on sheep blood agar, which is the preferred culture medium, but it can also grow on chocolate agar, Mueller-Hinton agar or brain heart infusion agar. (osmosis.org)