• Candida parapsilosis bloodstream isolates harboring a Y132F substitution in Erg11p in South Korea. (cdc.gov)
  • These Y132F isolates parapsilosis worldwide. (cdc.gov)
  • 86.7%, 26/30) than in non-Y132F fluconazole-resistant andida parapsilosis is the second most common species isolates (11.8%, 2/17) (Table). (cdc.gov)
  • Erg11p has also been detected in C. auris isolates from Alternatively, C. parapsilosis Y132F isolate emergence may Pakistan (10/16 isolates), India (12/17 isolates), and Ven- be associated with exogenous clonal transmission ( 4 ). (cdc.gov)
  • Materials & Methods: Mycelial growth rate of 26 Fusarium isolates, including F. verticillioides (n=6), F. proliferatum (n=18), F. solani (n=1), and F. oxysporum (n=1), in the presence of 42 C. parapsilosis strains was investigated by pourplate method. (ac.ir)
  • Conclusion: C. parapsilosis showed notable inhibitory activities against Fusarium isolates. (ac.ir)
  • We determined the ability of Candida parapsilosis isolates from single fungaemia episodes to form biofilms and we analysed biofilm subgroups for antifungal susceptibility and pathogenic potential. (unicatt.it)
  • In this study, we investigated the impact of 11 different commercial sanitizers at various concentrations and exposure times on biofilms consisting of clinical and nosocomial environmental isolates of Candida parapsilosis and Staphylococcus aureus . (bvsalud.org)
  • however, Candida glabrata and Candida parapsilosis tend to be the most common isolates after Candida albicans in invasive candidiasis. (medscape.com)
  • Cm-p5 Peptide Dimers Inhibit Biofilms of Candida albicans Clinical Isolates, C. parapsilosis and Fluconazole-Resistant Mutants of C. auris. (mpg.de)
  • C. parapsilosis and C. glabrata. (boku.ac.at)
  • By using disk diffusion assay, we evaluated the antifungal activity of lemongrass oil and citral against yeasts of Candida species (Candida albicans, C. glabrata, C. krusei, C. parapsilosis and C. tropicalis). (scielo.br)
  • Antifungal resistance is an increasing problem with fungal species from the Candida genus, particularly, Candida auris, Candida glabrata and Candida parapsilosis. (qub.ac.uk)
  • Candida albicans, C. tropicalis, C. glabrata, C. parapsilosis and C. guilhermondii were seeded into antibacterial (cefepime, meropenem, vancomycin, and piperacillin- tazobactam) gradient plates produced in Mueller-Hinton Agar. (bvsalud.org)
  • Candida parapsilosis is a fungal species of yeast that has become a significant cause of sepsis and of wound and tissue infections in immunocompromised people. (wikipedia.org)
  • C. parapsilosis is the most common non-C. albicans species of Candida and the second most common pathogen in superficial candidiasis after C. albicans. (wikipedia.org)
  • clarification needed] C. parapsilosis is encountered more frequently in nature than other species Candida, likely because it is one of the few species of the genus not restricted to humans. (wikipedia.org)
  • however, unlike in North America, C parapsilosis is the second most common Candida species in many Latin American countries. (medscape.com)
  • We do occasionally see outbreaks mainly with a species called Candida parapsilosis , but these outbreaks are actually very rare. (cdc.gov)
  • In this study, we compared the cytokine responses evoked by Candida albicans and C. parapsilosis . (bath.ac.uk)
  • C. parapsilosis -stimulated human peripheral blood mononuclear cells (PBMCs) produced similar quantities of tumor necrosis factor α and interleukin 6 and slightly lower amounts of interleukin 1β, compared with C. albicans-stimulated cells. (bath.ac.uk)
  • PBMCs stimulated with C. parapsilosis displayed a skewed T-helper cell response, producing more interleukin 10 and less interferon γ than cells stimulated with C. albicans . (bath.ac.uk)
  • Notably, C. parapsilosis induced much less interleukin 17 and interleukin 22 production as compared to C. albicans . (bath.ac.uk)
  • Decreased cytokine production after inhibition of dectin 1 revealed that this receptor plays a major role in the recognition of both C. albicans and C. parapsilosis . (bath.ac.uk)
  • Antifungal activity of EO and fractions were tested by a broth microdilution method, whereby minimum inhibitory concentration (MIC) was determined against several fungal organisms (Candida albicans, Candida krusei, Candida parapsilosis, Candida tropicalis, Cryptococcus gattii, and Cryptococcus neoformans). (researchgate.net)
  • Adhesion capacity and biofilm are important for C. parapsilosis, because C. parapilosis infection is mostly due to the use of in-dwelling devices. (wikipedia.org)
  • Therefore, effective sanitization practices, including regular cleaning with effective sanitizers , should be implemented to prevent C. parapsilosis /S. aureus biofilm formation in healthcare settings. (bvsalud.org)
  • C. parapsilosis is associated with thin, unstructured biofilms that consist of aggregated blastospores whose membranes contain more carbohydrate than protein. (wikipedia.org)
  • In vitro activity of sanitizers against mono- and polymicrobial biofilms of C. parapsilosis and S. aureus . (bvsalud.org)
  • Among the sanitizers tested, 0.5% and 2.0% chlorhexidine (CLX), 10% polyvinyl pyrrolidone ( PVP-I ), a disinfectant based on quaternary ammonium compound (QAC), 2% glutaraldehyde , and 0.55% orthophthalaldehyde (OPA) demonstrated efficacy against both C. parapsilosis and S. aureus in monospecies and mixed biofilms . (bvsalud.org)
  • C parapsilosis has been identified as the leading cause of candidemia secondary to medical instrumentation such as with central venous catheters, prosthetic devices, and nosocomial spread. (medscape.com)
  • Despite its clinical importance, little is known about the human immunological response to C. parapsilosis. (bath.ac.uk)
  • Conclusions: C. parapsilosis BF influences the clinical outcome in patients with fungaemia. (unicatt.it)
  • En mayo de 2007 obtuve el Certificate of Training in Molecular Biological Techniques en el Department of Molecular Biology y desde Junio de 2008 a Junio de 2009 completé el Certificate in Clinical Research en el Center for Translational Science Activities en Mayo Clinic College of Medicine, Rochester Minnesota. (unav.edu)
  • Un 40% de esos trabajos han sido publicados en revistas del primer cuartil entre las que destacan New England Journal of Medicine, Lancet, Lancet Infectious Diseases, Clinical Infectious Diseases, Clinical Microbiology Reviews, Antimicrobial Agents and Chemotherapy, Journal Clinical Microbiology, Journal Antimicrobial Chemotherapy, Mayo Clinic Proceedings y Malaria Journal. (unav.edu)
  • Amphotericin B and Fluconazole are often used in the treatment of C. parapsilosis infection. (wikipedia.org)
  • El objetivo del estudio fue determinar la concentración inhibitoria mínima (CIM) del fluconazol y anfotericina B de aislados de Candida de pacientes ambulatorios y hospitalizados en Paraguay de mayo del 2010 a agosto del 2011, aplicando criterios nuevos y antiguos para el fluconazolYeast infections are very important because of their relatively high frequency and increased resistance to antifungal agents, especially to azole derivatives, and in particular, to fluconazole. (bvsalud.org)
  • Immunocompromised individuals and surgical patients, particularly those undergoing surgery of the gastrointestinal tract, are at high risk for infection with C. parapsilosis. (wikipedia.org)
  • Ocular infection caused by C. parapsilosis has been reported after cataract extraction and with corticosteroid eye drop use. (wikipedia.org)
  • C. parapsilosis infection of the skin and gastrointestinal tract can occur, in which the production of pseudohyphae is associated with the elicitation of an inflammatory response. (wikipedia.org)
  • The risk of C. parapsilosis infection is increased in the setting of implanted medical devices, prostheses, and therapy with hyperalimentation solutions. (wikipedia.org)
  • C. parapsilosis is considered a killer yeast and fungal antagonist based on its ability to produce chemicals that exert cytotoxic effects on the cells of other organisms. (wikipedia.org)
  • We have developed an efficient gene deletion system for C. parapsilosis based on the repeated use of the dominant nourseothricin resistance marker (caSAT1) and its subsequent deletion by FLP-mediated, site-specific recombination. (elsevierpure.com)
  • These studies represent what we believe to be the first targeted disruption of a gene in C. parapsilosis and show that C. parapsilosis-secreted lipase is involved in disease pathogenesis. (elsevierpure.com)
  • These data improve understanding of the immune response triggered by C. parapsilosis , a first step for the future design of immunotherapeutic strategies for these infections. (bath.ac.uk)
  • Candidaalbicans and parapsilosis account for 80-90% of infections. (medscape.com)
  • When C. parapsilosis is in yeast form, its phenotype is smooth or cratered. (wikipedia.org)
  • C. parapsilosis is also a normal human commensal and it is one of the fungi most frequently isolated from human hands. (wikipedia.org)
  • Des analyses régulières de la résistance aux antifongiques dans les centres médicaux sont fortement recommandées, car les résultats permettront une prise en charge plus efficace de la candidose systémique chez les patients immunodéprimés. (who.int)
  • There are more than 20 species of Candida yeasts that can cause human infection, but most infections are caused by Candida albicans, C. glabrata , C. parapsilosis and C. tropicalis . (nih.gov)
  • Candida parapsilosis sensu stricto (C. parapsilosis SS) is a leading cause of invasive candidiasis in southern Europe, Latin America and Asia. (nih.gov)
  • The Candida parapsilosis complex comprises three genetically related species: Candida parapsilosis sensu stricto, Candida orthop- silosis and Candida metapsilosis. (uchile.cl)
  • During the last decade, Candida parapsilosis sensu stricto has become the second most commonly isolated yeast from patients with blood stream invasive fungal infections, following Candida albicans. (uchile.cl)
  • Being more frequently isolated from oral cavities with pathological conditions, 89.5% of the strains were reconfirmed to be Candida parapsilosis sensu stricto. (uchile.cl)
  • More than 70% of the Candida parapsilosis sensu stricto strains showed biofilm- forming capacity in both culture media, reflecting a statistically significant association between biofilm-forming capacity and the clinical conditions of the subjects from whom the strains were isolated. (uchile.cl)
  • Among the three complex species, Candida parapsilosis sensu stricto is a normal commensal in the oral cavity, being more frequently recovered in inflammatory conditions. (uchile.cl)
  • Gingival-periodontal disease may be a factor triggering overgrowth and virulence of Candida parapsilosis sensu stricto commensal strains. (uchile.cl)
  • CIENCIASMEDICASNEWS: Investigation of an unrecognized large-scale outbreak of Candida parapsilosis sensu stricto fungaemia in a tertiary-care hospital in China. (blogspot.com)
  • The lack of proper coordination between the clinical microbiology laboratory and infection control staff as part of public health control resulted in the failure to timely identify an outbreak, which led to the wide and long-term dissemination of C. parapsilosis sensu stricto in Hospital H. (blogspot.com)
  • The topic of my PhD thesis was to elucidate the role of fungal eicosanoid molecules and micronutrient acquisition in the virulence of human fungal pathogen Candida parapsilosis . (exeter.ac.uk)
  • New molecular genetic tools are providing additional and much-needed information regarding C. parapsilosis virulence. (nih.gov)
  • There is currently no consensus on the treatment of invasive candidiasis caused by C. parapsilosis, although the therapeutic approach typically includes the removal of foreign bodies such as implanted prostheses and the administration of systemic antifungal therapy. (wikipedia.org)
  • Candida parapsilosis is an emerging major human pathogen that has dramatically increased in significance and prevalence over the past 2 decades, such that C. parapsilosis is now one of the leading causes of invasive candidal disease. (nih.gov)
  • The cell free extracts of Candida parapsilosis ATCC 7330 are more efficient than the whole resting cells of the yeast in the synthesis of directly usable gold nanoparticles as revealed by this systematic study. (springeropen.com)
  • When C. parapsilosis is in yeast form, its phenotype is smooth or cratered. (wikipedia.org)
  • C. parapsilosis is considered a killer yeast and fungal antagonist based on its ability to produce chemicals that exert cytotoxic effects on the cells of other organisms. (wikipedia.org)
  • The mitochondrially translated product called subunit 6 was extracted from the yeast Candida parapsilosis mitochondria using an organic solvent mixture and purified by reverse-phase HPLC. (nih.gov)
  • Overall, C. parapsilosis SS was the primary contributor of yeast related blood stream infections, accounting for 24% of infections. (nih.gov)
  • Aspergillus fumigatus, Candida parapsilosis, Tyromyces palustris, Gloeophyllum trabeum, Penicillium chrysogenum, and Phanerochaete chrysosporium are examples of fungi able to degrade hydroquinone [ 5 - 9 ]. (hindawi.com)
  • Detection and Characterization of Two Phenotypes of Candida parapsilosis in South Korea: Clinical Features and Microbiological Findings. (bvsalud.org)
  • In this study, we aimed to determine the prevalence and associated mutations of fluconazole-resistance phenotypes of C. parapsilosis SS isolated from patients with underlying immunodeficiencies at NIH Clinical Center. (nih.gov)
  • C. parapsilosis infection of the skin and gastrointestinal tract can occur, in which the production of pseudohyphae is associated with the elicitation of an inflammatory response. (wikipedia.org)
  • Candida parapsilosis was discovered in Puerto Rico in 1928 by Ashford from a diarrheal stool. (wikipedia.org)
  • C. parapsilosis is also a normal human commensal and it is one of the fungi most frequently isolated from human hands. (wikipedia.org)
  • El complejo C. parapsilosis incluye las especies íntimamente relacionadas C. orthopsilosis y C. metapsilosis. (bvsalud.org)
  • C. parapsilosis infections are especially associated with hyperalimentation solutions, prosthetic devices, and indwelling catheters, as well as the nosocomial spread of disease through the hands of health care workers. (nih.gov)
  • We report a case of Candida parapsilosis osteomyelitis in an immunocompetent patient with no prior surgical history. (hcahealthcare.com)
  • The emerging information will provide a deeper understanding of C. parapsilosis pathogenesis and facilitate the development of new therapeutic approaches for treating C. parapsilosis infections. (nih.gov)
  • Candida parapsilosis resistance to fluconazole: molecular mechanisms and in vivo impact in infected Galleria mellonella larvae. (cdc.gov)
  • A Rare Case of Candida parapsilosis Lumbar Discitis With Osteomyelitis" by Patrick Duplan, Mohammad B. Memon et al. (hcahealthcare.com)
  • Duplan P, Memon MB, Choudhry H, Patterson J. A Rare Case of Candida parapsilosis Lumbar Discitis With Osteomyelitis. (hcahealthcare.com)
  • Lastly, Candida parapsilosis is also often found in immune-weakened individuals and is highly resistant to antimicrobial drugs . (thecandidadiet.com)