• Systemic cell-mediated and antibody responses in infants with respiratory syncytial virus infections. (microbiologyresearch.org)
  • Respiratory tract infections are associated with member viruses such as human respiratory syncytial virus. (wikipedia.org)
  • Viruses in this family are often associated with respiratory infections, and are transmitted through respiratory secretions. (wikipedia.org)
  • There are many other viruses that infect the respiratory tract and there is a large overlap of symptoms among these infections. (quidel.com)
  • hMPV infection has clinical features that range from mild upper respiratory tract infections (URTIs) to lower respiratory tract infections (LRTIs) complicated by significant wheezing, leading to life-threatening bronchiolitis and pneumonia, in all age groups. (medscape.com)
  • Human respiratory syncytial virus (RSV) is a ubiquitous virus of worldwide distribution and is the leading cause of infant morbidity from respiratory infections. (intechopen.com)
  • We conducted a prospective study using sentinel-based influenza surveillance to detect RSV by real time PCR in patients with acute respiratory infections, enrolled during two seasons (2014/15, 2015/16). (who.int)
  • RSV remains important viral etiological agent causing influenza-like illness and severe acute respiratory infections especially among infants in Morocco. (who.int)
  • Methods: Acute respiratory tract infections were collected from 13 hospitals in Shanghai from 2015 to 2021. (bvsalud.org)
  • These three viral pathogens cause acute respiratory tract infections with substantial disease burden in the young, the elderly, and the immune-compromised. (bvsalud.org)
  • BACKGROUND: To investigate the impact of the coronavirus disease 2019 (COVID-19) outbreak on the prevalence of respiratory viruses among pediatric patients with acute respiratory infections in Xuzhou from 2015-2021. (bvsalud.org)
  • HRSV is a leading cause of lower respiratory tract infections in infants, elderly, and immunosuppressed. (geneticpcr.com)
  • RSV is a 100-350 nm enveloped virus belonging to the Paramyxoviridae ,genus Pneumovirus, that causes minor respiratory infections in adults and bronchitis and bronchopneumonia in children. (bio-rad-antibodies.com)
  • The test is intended for use as an aid in the diagnosis of acute respiratory syncytial viral infections. (urgentmednetwork.com)
  • 2 ). In Morocco, 13% of Study design and case day during October through April for paediatric deaths during 2012 were due definition specimen collection to acute respiratory infections ( 3 ). (who.int)
  • Human metapneumovirus (hMPV) is a major cause of acute respiratory infections ranging from wheezing to bronchiolitis and pneumonia in children worldwide. (biomedcentral.com)
  • Acute respiratory tract infections are one of the most common diseases in adults and children in the world, which is facing a heavy burden on the health system and society. (pharmcourse.com)
  • A similar trend was found in China, in a study of pediatric patients with viral respiratory tract infections in Shanghai. (pharmcourse.com)
  • A downward trend in the prevalence of respiratory viruses, including influenza, parainfluenza virus, adenovirus, coronaviruses (excluding SARS-CoV-2), human metapneumovirus, rhinovirus, and respiratory syncytial virus infections, was also observed in other national studies. (pharmcourse.com)
  • Epidemiologists believe that several factors played a role in this trend: the high virulence of SARS-CoV-2, which provided a powerful surge of coronavirus infection and its prevalence in the picture of viral respiratory infections, and the widespread use of preventive hygiene measures, as well as the massive introduction of quarantine, which further allowed to control the transmission of other respiratory viruses. (pharmcourse.com)
  • This study, conducted by scientists at the University of Bristol in collaboration with pharmaceutical giant Pfizer, was the first to compare hospital admissions for respiratory infections caused by SARS-CoV-2 and other respiratory infections. (pharmcourse.com)
  • Using data from 135014 hospitalizations from two large hospitals in Bristol between August 2020 and November 2021, the researchers found that 12557 hospitalizations were associated with acute lower respiratory illness in patients presenting with symptoms of respiratory infections (including cough, fever) or radiological evidence of pathology. (pharmcourse.com)
  • Anticipating new epidemiological season, let's talk about transmission routes, clinical symptoms and treatment tactics for respiratory viral infections not associated with SARS-CoV-2. (pharmcourse.com)
  • Respiratory infections are commonly caused by viruses and at present the three most common respiratory viruses within the UK are coronavirus (COVID-19), influenza virus (flu) and respiratory syncytical virus (RSV). (nonacus.com)
  • Human parainfluenza viruses , or HPIV, are a group of viruses that commonly cause respiratory tract infections, especially in children. (osmosis.org)
  • In fact, they are the second most common cause of acute respiratory infections in children under 5 years of age. (osmosis.org)
  • HPIVs causes acute respiratory infections, especially in children under five years. (osmosis.org)
  • They cause respiratory infections such as croup , bronchiolitis , and Pneumonia , which are spread through infected droplets in the air and contaminated surfaces. (osmosis.org)
  • Clinical symptoms from HMPV-infect- movirus (HMPV) infection in children with respiratory dis- ed children have included nonproductive cough, nasal con- ease of similar severity as respiratory syncytial virus (RSV) gestion, and wheezing (5,6,8,11). (cdc.gov)
  • Among children hospitalized with respiratory illness, the incidence of HMPV infection was less than RSV, but clini- cal disease severity mirrored that of RSV infection. (cdc.gov)
  • Pulmonary A2 strain respiratory syncytial virus infection of BALB/c laboratory mice persisted for up to 7 days after initial infection with peak virus titres being recovered on day 4. (microbiologyresearch.org)
  • This local CTL response was preceded by a rapid transient virus-specific lymphocyte transformation response which was detectable only 3 days after intranasal infection. (microbiologyresearch.org)
  • IgG was the first class of virus-specific immunoglobulin to be detected in the lungs of infected animals after experimental infection. (microbiologyresearch.org)
  • However, IgG was not detected until day 10 post-infection, 5 days after the initial decline of virus shedding. (microbiologyresearch.org)
  • Immunoglobulin class specific antibody response in serum, spleen, lungs and bronchioal- veolar washings after primary and secondary Sendai virus infection of germ free mice. (microbiologyresearch.org)
  • Study of experimental RS virus infection in cotton rats. (microbiologyresearch.org)
  • Primary respiratory syncytial virus infection in mice. (microbiologyresearch.org)
  • It is a negative-strand RNA virus that is the second most common cause of lower respiratory infection in young children. (wikipedia.org)
  • it is an upper respiratory infection. (wikipedia.org)
  • Respiratory syncytial virus (RSV) is a very common cause of respiratory tract infection especially in young children. (quidel.com)
  • RSV is a very common virus infection that often resembles the common cold with mild symptoms such as a runny nose, coughing and low-grade fever. (quidel.com)
  • When an RSV infection becomes more serious and progresses to bronchiolitis, patient management goals are to relieve respiratory distress, alleviate airway obstruction and improve oxygen levels. (quidel.com)
  • Infection with hMPV causes a broad spectrum of respiratory illness, from mild symptoms to severe cough, bronchiolitis, and pneumonia. (medscape.com)
  • Immunosuppressed persons, such as stem cell transplant or organ transplant recipients, may require CT scanning to clarify upper respiratory versus lower respiratory infection. (medscape.com)
  • Nearly 100% of children in the USA are infected with the virus by 2 to 3 years of age, several hundred infants may die directly from the infection, while the deaths of an additional several thousand may be attributed to RSV-related complications ( Nair et al, 2010 ). (intechopen.com)
  • Hepatitis E virus (HEV), an important agent of viral hepatitis worldwide, can cause severe courses of infection in pregnant women and immunosuppressed patients. (mdpi.com)
  • The proportion of positive RSV infection was higher in patients hospitalized with acute respiratory infection compared to those with mild symptoms in out-patient clinics. (who.int)
  • La proportion d'infections positives au VRS était plus élevée chez les patients hospitalisés pour une infection respiratoire aiguë que chez les patients en consultation externe souffrant de légers symptômes. (who.int)
  • In the 1960s, vaccination with formalin-inactivated paramyxovirus preparations - respiratory syncytial virus (RSV) and measles virus (MV) - resulted in predisposition for enhanced disease upon natural infection. (eur.nl)
  • Objective: To study the infection status and epidemiological characteristics of parainfluenza virus (PIV) in acute respiratory tract infection adult cases in Shanghai from 2015 to 2021, and to provide a scientific basis for preventing and controlling PIV. (bvsalud.org)
  • The positive rate of PIV was 2.61% (133/5 104), compared with 2.32% (55/2 369) and 2.85% (78/2 735) in influenza-like cases (ILI) and severe acute respiratory infection (SARI) cases, respectively. (bvsalud.org)
  • METHODS: Severe acute respiratory infection (SARI) cases in hospitalized children were collected from 2015-2021 in Xuzhou, China. (bvsalud.org)
  • Respiratory syncytial virus (RSV) is the most frequent cause of lower respiratory tract infection in infants and children and the second most common viral cause of pneumonia in adults. (medscape.com)
  • Influenza pneumonia: Amantadine hydrochloride and rimantadine hydrochloride are approved for the prevention and treatment of influenza A virus infection. (medscape.com)
  • Pertussis is an acute infection of the respiratory tract caused by Bordetella pertussis. (gkhospital.in)
  • This team was named as "comparative respiratory virology" and include both medical and veterinary scientist who are specialists in the field of respiratory infection of equines and humans. (coronavirus.fr)
  • Respiratory syncytial virus is a single-stranded (negative strand) RNA virus of the Paramyxoviridae family.1 It is the causative agent of a highly contagious, acute, viral infection of the respiratory tract. (urgentmednetwork.com)
  • Of these patients, 55% of cases (6909 people) were associated with a respiratory infection not associated with SARS-CoV-2. (pharmcourse.com)
  • Background: Infection by pathogenic viruses results in rapid epithelial damage and significantly impacts on the condition of the upper respiratory tract, thus the effects of viral infection may induce changes in microbiota. (korea.ac.kr)
  • Understanding these viruses, their genomes and mechanisms of infection helps us to reduce the rate of viral transmission and improve patient care. (nonacus.com)
  • To propagate infection, COVID-19, flu and RSV produce spherical shaped virions which are transmitted within respiratory droplets, spread via direct contact, coughing or sneezing 3,4 . (nonacus.com)
  • The ability of a pathogenic virus to lie dormant within a cell (latent infection). (lookformedical.com)
  • ABSTRACT Respiratory syncytial virus (RSV) is a leading cause of mortality and morbidity in young infants, little was known on its circulation types and patterns in Morocco. (who.int)
  • Respiratory syncytial virus, or RSV, mostly affects the elderly and infants. (microbes.info)
  • Parainfluenza virus (PIV) is second in importance only to RSV as a cause of lower respiratory tract disease in children and pneumonia and bronchiolitis in infants younger than 6 months. (medscape.com)
  • Epidemiology With an attack rate approaching 100% among susceptible individuals, HRSV is a major respiratory pathogen among young children (particularly those 2-3 months of age) and the foremost cause of lower respiratory disease among infants. (gkhospital.in)
  • Paramyxoviridae belonging to the same subfamily, eases related to new vaccines. (cdc.gov)
  • A genus of the family PARAMYXOVIRIDAE (subfamily PNEUMOVIRINAE ) where the human and bovine virions have neither hemagglutinin nor neuraminidase activity. (nih.gov)
  • A genus of the family HERPESVIRIDAE, subfamily ALPHAHERPESVIRINAE, consisting of herpes simplex-like viruses. (lookformedical.com)
  • Pneumovirinae , as respiratory syncytial virus (RSV) (1,2). (cdc.gov)
  • Specimens were tested influenza-like illness seen in an outpatient clinic was for HMPV, RSV, influenza, and parainfluenza viruses by reported to have HMPV and negative cultures for influen- reverse transcription-polymerase chain reaction assays. (cdc.gov)
  • 641 children enrolled in the network from August 2000 virus culture or confirmed RT-PCR was considered a pos- through September 2001 (27 children were hospitalized itive test for respiratory viruses other than HMPV. (cdc.gov)
  • Findings in patients with significant lower respiratory tract disease are indistinguishable between hMPV and other causes of viral pneumonia or bronchiolitis. (medscape.com)
  • Although it is hypothesized that the human virus originated from birds, the serological evidence that hMPV has been widespread in humans since at least 1958 suggests a zoonotic divergence before this time. (medscape.com)
  • hMPV was identified in stored nasopharyngeal samples from children with respiratory illness using reverse transcription-polymerase chain reaction (RT-PCR) amplification techniques. (medscape.com)
  • In this study, visual RT-LAMP assay for hMPV was performed in one step with the addition of hydroxynaphthol blue (HNB), and were used to detect respiratory samples. (biomedcentral.com)
  • Currently, the most common hMPV detection methods are by virus isolation, enzyme-linked immunoassays, McAb immuno-fluorescent assays and molecular biology methods based on the polymerase chain reaction (PCR, RT-PCR, nested PCR, and real-time PCR). (biomedcentral.com)
  • Additionally, RNA can be amplified by reverse transcription coupled with LAMP (RT-LAMP) in one step, making it suitable to detect RNA viruses such as hMPV. (biomedcentral.com)
  • The direct fluorescent antibody (DFA) method allows detection of virus within 2-3 hours, but is labor intensive and requires considerable experience. (quidel.com)
  • Blood samples were collected from 406 cattle older than 6 months of age of both sexes for the detection of antibodies against the RC and PI3 viruses by viral neutralization test. (edu.pe)
  • The HRSV-AB dtec-RT-qPCR comprises a series of specific targeted reagents designed for Human respiratory syncytial virus A/B detection by using qPCR. (geneticpcr.com)
  • Detection of bovine respiratory syncytial virus by PCR is also part of the service Bovine Respiratory Profile 1 (PCR Profile). (laboklin.com)
  • The QuickVue RSV Test is a dipstick immunoassay which allows for the rapid, qualitative detection of respiratory syncytial virus (RSV) antigen (viral fusion protein) directly from nasopharyngeal swab, nasopharyngeal aspirate, or nasal/nasopharyngeal wash specimens for symptomatic pediatric patients (eighteen years of age and younger). (urgentmednetwork.com)
  • This virology team is headed by Astrid Vabret, and the two key words defining the research field are Nidovirales and Paramyxoviridae (specially measles and respiratory syncytial virus). (coronavirus.fr)
  • Human respiratory syncytial virus (HRSV) is an enveloped, single-stranded RNA virus and a member of the family Paramyxoviridae. (gkhospital.in)
  • 2000).The Respiratory Syncytial Virus Small Hydrophobic Protein (RSV-SH)Human respiratory syncytial virus (hRSV) belongs for the Paramyxoviridae household in the pneumovirus genus. (piminhibitor.com)
  • hRSV exists as two antigenically distinct subgroups, A and B, both capable of inducing serious reduce respiratory tract (LRT) disease in humans (Hall et al. (piminhibitor.com)
  • RSV is readily spread from contact with respiratory secretions from infected individuals or contaminated surfaces and objects. (quidel.com)
  • decreases were seen in tissues and mucosal secretions, critically decreasing potential for virus transmission. (cdc.gov)
  • Human respiratory syncytial virus is an enveloped, non-segmented, negative-sense, single-stranded RNA virus of the family Paramyxoviridae. (geneticpcr.com)
  • Rhinoviruses are nonenveloped, single-stranded RNA viruses in the family Picornaviridae that together are the major cause of the "common cold" (up to 50% of cases). (gkhospital.in)
  • Néstor Falcón, P. / Serological evaluation of respiratory syncytial (RS) and parainfluenza 3 (PI3) viruses in cattle from cusco . (edu.pe)
  • Galim Solís, G , Hermelinda Rivera, G & Néstor Falcón, P 2010, ' Serological evaluation of respiratory syncytial (RS) and parainfluenza 3 (PI3) viruses in cattle from cusco ', Revista de Investigaciones Veterinarias del Peru , pp. 204-209. (edu.pe)
  • Antibodies against bovine respiratory syncytial virus can be detected by means of the serological Bovine Respiratory Profile . (laboklin.com)
  • Influenza virus(IFV), respiratory syncytial virus (RSV), human parainfluenza virus type 3(hPIV-3), human rhinovirus (hRV), human adenovirus(hAdV), human coronavirus(hCoV) were detected by real-time fluorescence polymerase chain reaction(RT-qPCR), and the results were statistically analyzed by SPSS 23.0 software. (bvsalud.org)
  • Moreover, the RT-LAMP assay showed good specificity and no cross-reactivity was observed with human rhinovirus (HRV), human respiratory syncytial Virus (RSV), or influenza virus A/PR/8/34 (H1N1). (biomedcentral.com)
  • We examined the utility of AG for the selective capture of human immunodeficiency virus virus-like particles, influenza A, and measles virus. (emory.edu)
  • A leucine zipper structure present in the measles virus fusion protein is not required for its tetramerization but is essential for fusion. (microbiologyresearch.org)
  • Type I glycoprotein that facilitates fusion between the virus and the host cell membrane. (wikipedia.org)
  • First, the virus binds to HN glycoprotein receptors expressed on the surface of the cell. (wikipedia.org)
  • Mouse anti Respiratory syncitial virus, major surface glycoprotein G antibody, clone 8C5 recognizes the major glycoprotein G of Respiratory Syncytial virus (RSV). (bio-rad-antibodies.com)
  • Experiments using a recombinant vesicular stomatitis virus expressing the EKV-1 envelope glycoprotein indicate EKV-1 has very broad tropism and can efficiently enter nearly all types of human cells. (wikimili.com)
  • Experiments using a recombinant vesicular stomatitis virus expressing the EKV-2 envelope glycoprotein indicate EKV-2 has very broad tropism similar to EKV-1. (wikimili.com)
  • The assay uses a recombinant vesicular stomatitis virus expressing NiV glycoprotein and a fluorescent protein. (cdc.gov)
  • The structure of the fusion glycoprotein of Newcastle disease virus suggests a novel paradigm for the molecular mechanism of membrane fusion. (microbiologyresearch.org)
  • Nipah virus (NiV) is a highly pathogenic paramyxovirus with a high case fatality rate. (cdc.gov)
  • Relevant information was registered, and respiratory specimens were sampled to detect respiratory pathogens by multiplex PCR. (bvsalud.org)
  • the overall positive rate of the respiratory pathogens was 29.37% (1 499/5 104). (bvsalud.org)
  • Paramyxoviridae, a large family of enveloped viruses harboring a nonsegmented negative-sense RNA genome, include important human pathogens as measles, mumps, respiratory syncytial virus (RSV), parainfluenza viruses, and henipaviruses, which cause some of the deadliest emerging zoonoses. (covid19criticalcare.com)
  • Antibodies against both viruses were detected in 76.4% of the animals. (edu.pe)
  • One child with prospective study of acute respiratory illness among inpa- tient children from two U.S. cities. (cdc.gov)
  • Bas-Congo virus (BASV) was discovered in 2009 in the Democratic Republic of Congo in a blood sample collected from a 32-year-old male who survived a severe illness resembling hemorrhagic fever. (wikimili.com)
  • These viruses leave the cell by using neuraminidase, which cleaves the sialic acid sugars of the cell membrane , allow the newly created viruses to simply bud out of the cell. (osmosis.org)
  • Molluscum contagiosum virus is an obligate human pathogen that causes distinctive proliferative skin lesions. (gkhospital.in)
  • Since the emergence of the SARS-CoV-2 pathogen, the virological distribution of respiratory viruses has changed significantly. (pharmcourse.com)
  • Thus, we aimed to define the healthy microbiota and the viral pathogen-affected microbiota in the upper respiratory tract. (korea.ac.kr)
  • The symptoms may worsen with time, and new respiratory signs and symptoms, such as dyspnea and cyanosis, appear. (medscape.com)
  • These three viruses share similarities including causing similar symptoms, being highly contagious, and increased transmission in colder months, however their viral genomes and particle structures are uniquely different. (nonacus.com)
  • Virus antigen within the lungs was found to be restricted essentially to the alveolar regions. (microbiologyresearch.org)
  • Pneumoviruses are pleomorphic, capable of producing spherical and filamentous, enveloped virions (virus particles) that vary in size from 150 to 200 nm in diameter. (wikipedia.org)
  • Tibrovirus virions are enveloped, but only the morphology of Tibrogargan virus and Sweetwater branch virus have been observed by electron microscopy. (wikimili.com)
  • This segmented genome enables antigenic shift , in which segment reassortment can occur with other circulating human and animal viruses, this can create a new strain of the virus which has novel antigenic surface proteins and gives it the capability to easily infect individuals 2 . (nonacus.com)
  • Diagnostic tests performed on specimens taken from the respiratory tract provide a useful aid to the diagnosis of RSV. (quidel.com)
  • There are a number of methods available to laboratories to detect RSV in respiratory specimens from patients. (quidel.com)
  • 256, where antibody titres of 16-64 against RS and PI3 viruses were detected in 61.4 and 58.3% of the animals. (edu.pe)
  • To download a certificate of analysis for Human respiratory syncytial virus ( VR-1803 ), enter the lot number exactly as it appears on your product label or packing slip. (atcc.org)
  • The certificate of analysis for that lot of Human respiratory syncytial virus ( VR-1803 ) is not currently available online. (atcc.org)
  • Enveloped viruses, which contain an outer lipoprotein coat, constitute the largest group of pathogenic viruses to humans. (emory.edu)
  • Nipah virus (NiV) causes a highly lethal disease in humans who present with acute respiratory or neurological signs. (cdc.gov)
  • 1990). Although the virus was isolated greater than half a century ago, no effective licensed remedy or vaccine is out there for the basic population, despite promising RSV vaccine candidates in clinical trials. (piminhibitor.com)
  • Broad spectrum oral antivirals are urgently needed for the early treatment of many RNA viruses of clinical concern. (cdc.gov)
  • Once sufficient P, N, L, and M2 proteins are available to create a capsid around the newly replicated genome, the virus undergoes replication. (wikipedia.org)
  • This enveloped virus has a negative-sense single-strand RNA genome 15.2 kb extended that encodes 10 sub-genomic mRNAs and 11 proteins (Fields et al. (piminhibitor.com)
  • 38 However, sheep-and goatpox viruses will have subtle genetic changes to their genomes over time which can be identified using genome sequencing. (anipedia.org)
  • COVID-19 is caused by a coronavirus known as SARS-CoV-2 (Severe Acute Respiratory Syndrome), the SARS-CoV-2 genome of 29.9 kb is significantly larger than that of influenza and RSV at 13.5 kb and 15.2 kb respectively (see table). (nonacus.com)
  • In fact, the SARS-CoV-2 genome is currently the largest identified animal RNA virus, mainly due to its 'proof-reading' capabilities which identifies and corrects errors that arise during viral replication 1 . (nonacus.com)
  • however, the genome of influenza and RSV is negatively sensed, whereas the SARS-CoV-2 genome is positively sensed, which gives this virus the ability to function as messenger RNA and the genome can be directly translated into protein inside the host cell. (nonacus.com)
  • This virus is second only to the respiratory syncytial virus (RSV) as the most commonly identified cause of pediatric LRTI. (medscape.com)
  • The virus occurs throughout the world, most commonly causing disease in childhood. (gkhospital.in)
  • Sendai virus-induced cell mediated cytotoxicity in vitro: the role of viral glycoproteins in cell mediated cytotoxicity. (microbiologyresearch.org)
  • We found that 3-F-4-MeO-Bn, 3-CN-Bn, and 4-CN-Bn sn-2 glycerol modifications improved antiviral activity compared to V2043 when tested in vitro against clinically important RNA viruses from 5 virus families. (cdc.gov)
  • Nous avons réalisé une étude prospective en recourant à la surveillance de la grippe basée sur des sites sentinelles dans le but de dépister le VRS grâce à la PCR en temps réel chez des patients souffrant d'infections respiratoires aiguës recrutés au cours de deux saisons (2014-2015 et 2015-2016). (who.int)
  • Methods: We analyzed the upper respiratory tract bacterial content of 57 healthy asymptomatic people (17 health-care workers and 40 community people) and 59 patients acutely infected with influenza, parainfluenza, rhino, respiratory syncytial, corona, adeno, or metapneumo viruses using culture-independent pyrosequencing. (korea.ac.kr)