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  • Cervarix
  • The intramuscular administration of AcHERV-based HPV16L1 and HPV18L1 DNA vaccines induced antigen-specific serum IgG, vaginal IgA, and neutralizing antibodies to levels comparable to those achieved using the commercially marketed vaccine Cervarix. (pubmedcentralcanada.ca)
  • Another vaccine, Cervarix TM (HPV2), was released in the U.S. in 2009 10 but is no longer available in the US. (acpeds.org)
  • cottontail rabbit papillo
  • Breitburd F, Kirnbauer R, Hubbert NL et al (1995) Immunization with virus-like particles from cottontail rabbit papillomavirus (CRPV) can protect against experimental CRPV infection. (springer.com)
  • The native cottontail rabbit papillomavirus (CRPV) L1 capsid protein gene was expressed transgenically via Agrobacterium tumefaciens transformation and transiently via a tobacco mosaic virus (TMV) vector in Nicotiana spp. (asm.org)
  • Cottontail rabbit papillomavirus (CRPV) in rabbits provides a robust model to study viral interaction with the host and progression to cancer and for viral vaccine studies. (asm.org)
  • genotypes
  • Currently, there are two FDA-approved vaccines available to provide protection against the most common genotypes of HPV. (uspharmacist.com)
  • The participants were examined gynecologically and a vaginal lavage was taken, which was molecular genetically examined for 54 different human papillomavirus genotypes and 18 other STIs. (springer.com)
  • Merck
  • NCI, a component of the National Institutes of Health , licensed the technology to two pharmaceutical companies-Merck and GSK-to develop HPV vaccines for widespread distribution. (sanevax.org)
  • When criticized for their aggressive marketing, Merck countered that they were performing a public service by raising awareness about the human papillomavirus and weren't selling anything. (educate-yourself.org)
  • vectors
  • Here we investigated CD8 + T cell responses in the female mouse cervicovaginal mucosa after intravaginal immunization with human papillomavirus vectors (HPV pseudoviruses) that transiently expressed a model antigen, respiratory syncytial virus (RSV) M/M2, in cervicovaginal keratinocytes. (jci.org)
  • Moreover, the possibility of repeated dosing indicates the utility of AcHERV system for reusable vectors of other viral pathogen vaccines. (pubmedcentralcanada.ca)
  • disease
  • A higher standard of safety is expected of vaccines compared with other medical interventions because vaccines are generally administered to healthy people to prevent disease. (jimmunol.org)
  • The global burden of disease caused by both human immunodeficiency virus (HIV) and human papillomavirus (HPV) is the greatest in the developing world, with the highest rates in sub-Saharan Africa. (academicjournals.org)
  • 1 With the high burden of this disease, studies are being conducted to evaluate the cost-effectiveness of preventive measures, including the HPV vaccines. (uspharmacist.com)
  • The objective of our study was to assess meningococcal ACWY (MenACWY) vaccine uptake among men who have sex with men (MSM) during an ongoing, invasive meningococcal disease outbreak in Southern Califo. (bioportfolio.com)
  • diseases
  • and to National Institutes of Health 's National Institute of Allergy and Infectious Diseases (NIAID) for information on research and the development of new vaccines. (mercola.com)
  • The induction of persistent intraepithelial CD8 + T cell responses may be key to the development of vaccines against mucosally transmitted pathogens, particularly for sexually transmitted diseases. (jci.org)
  • With a view to initiating discussion and research into the possible future role of HPV vaccines in Australia, on 12 December 2003, the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases brought together representatives from eight Australian research groups currently involved in HPV research and both vaccine manufacturers with current HPV vaccine candidates. (health.gov.au)
  • FDA (2006) FDA licenses new vaccine for prevention of cervical cancer and other diseases in females caused by human papillomavirus. (springer.com)
  • doses
  • The vaccine is administered by intramuscular injection, and the recommended schedule is a 3-dose series with the second and third doses administered 2 and 6 months after the first dose. (cdc.gov)
  • After receiving the first of three doses of the vaccine, Naomi suffered convulsions, severe back and neck pain, and lost her ability to walk. (mercola.com)
  • This vaccine is also given in three doses over a 6-month period. (sanevax.org)
  • Unsolicited non-serious adverse events (AEs) and serious adverse events (SAEs) will be collected from Visit 1 to Visit 2, or to Visit 3 for those subjects receiving 2 doses of study vaccine. (bioportfolio.com)
  • The girls will receive the vaccines doses at their schools (school-based program). (bioportfolio.com)
  • SaneVax
  • Relying upon the data from the CDC's, Vaccine Adverse Events Reporting System ( VAERS ), the vaccine watch organization Sanevax determined that, since Gardasil's launch in 2006 until November 2012, the HPV vaccine was linked to 121 deaths and over 27,485 medical injuries of young girls , some as young as 11 years old. (educate-yourself.org)
  • cytology
  • To investigate the most suitable method for low-income areas in China, we conducted a health economic analysis comparing three methods: visual inspection with acetic acid and Lugol's iodine (VIA/VILI), ThinPrep cytology test (TCT), and human papillomavirus (HPV) test. (biomedcentral.com)
  • Clinical
  • Despite these advantages and initial high hopes, research progress in this area since the first report about two decades ago has been slow, with only a few DNA vaccines reaching clinical trials to date , . (pubmedcentralcanada.ca)
  • Zur Hausen H (2002) Papillomaviruses and cancer: from basic studies to clinical application. (springer.com)
  • protein
  • Bouvard V, Storey A, Pim D et al (1994) Characterization of the human papillomavirus E2 protein: evidence of trans-activation and trans-repression in cervical keratinocytes. (springer.com)
  • Conrad M, Bubb VJ, Schlegel R (1993) The human papillomavirus type 6 and 16 E5 proteins are membrane-associated proteins which associated with the 16-kilodalton pore-forming protein. (springer.com)
  • Naturally-occurring variants of Human papillomavirus (HPV) 58 have been defined as lineages and sublineages but little is known about the impact of this diversity on protein function. (bioportfolio.com)
  • Papillomavirus E7 proteins have been shown to interact with various regulators of the cell cycle including RETINOBLASTOMA PROTEIN and certain cyclin-dependent kinase inhibitors. (bioportfolio.com)