• Intraductal papillary mucinous neoplasm of the ileal heterotopic pancreas in a patient with hereditary non-polyposis colorectal cancer: A case report. (wjgnet.com)
  • These adenocarcinomas start within the part of the pancreas that makes digestive enzymes. (wikipedia.org)
  • PANCREATIC DUCTAL ADENOCARCINOMA CLINICAL FEATURES Ductal adenocarcinoma of the pancreas is the most common malignant neoplasm of the pancreas. (coek.info)
  • Yilmaz & Deshpande occasionally, they are cystic and thus can mimic primary cystic neoplasms of the pancreas. (coek.info)
  • Serum CA19-9 is an important complementary tool within the context of preoperative investigation of cystic neoplasms of the pancreas. (univr.it)
  • The international consensus guidelines for intraductal papillary mucinous neoplasm of the pancreas (IPMN) presented clinical features as indications for surgery. (biomedcentral.com)
  • For non-invasive IPMN, including low-grade and high-grade dysplasia, surveillance with a focus on the remnant pancreas is recommended because early detection of a malignant lesion and surgical resection may improve the prognosis. (biomedcentral.com)
  • Recommendations are made for the appropriate use of bile duct brushing cytology obtained via endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasound (EUS)-fine-needle aspiration (FNA) cytology of mass lesions in the pancreas. (cytojournal.com)
  • There are many cystic lesions of the pancreas, of which most are pseudocysts and only 5-15% are neoplastic. (utoronto.ca)
  • Intraductal papillary mucinous neoplasm (IPMN) is a non-invasive mucin-producing neoplasm of the pancreas arising from the main pancreatic duct or side-branches. (utoronto.ca)
  • In contrast, mucinous cystic neoplasms of the pancreas occur almost exclusively in women, arise in the body/tail, do not communicate with a pancreatic duct, and exhibit dense ovarian-type stroma. (utoronto.ca)
  • Population-Based Analysis of Neoplastic Changes in Cystic Lesions of the Pancreas. (ucsf.edu)
  • With increasing use and enhanced accuracy of cross-sectional imaging, the diagnosis of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas has increased over the last few decades. (biomedcentral.com)
  • Expression of Matrix Metalloproteinases in Intraductal Papillary Mucinous Neoplasm of the Pancreas. (cancerindex.org)
  • The objective of the authors was to develop a monoclonal antibody to distinguish adenocarcinoma and precancerous intraductal papillary mucinous neoplasia (IPMN) from benign epithelium. (elsevierpure.com)
  • To study the relationship between carcinoembryonic antigen (CEA) level, intraductal papillary mucinous neoplasm (IPMN) subtype, and the presence of invasive carcinoma. (gastrores.org)
  • However, there was no correlation between CEA level and cystic mucinous secretions or mucinous epithelial cytoplasm CEA staining, mucin glycoprotein expression, size of lesion, grade of dysplasia or presence of invasive carcinoma. (gastrores.org)
  • IPMN is thought to represent a precursor lesion to pancreatic adenocarcinoma due to its association with invasive carcinoma [ 5 ]. (gastrores.org)
  • In an attempt to identify pancreatic cystic lesions with an increased risk of associated invasive adenocarcinoma, carcinoembryonic antigen (CEA) level has emerged over the last few decades as a tool to assess pancreatic cystic fluid pre-operatively. (gastrores.org)
  • In addition to CEA being used to stratify mucinous vs. non-mucinous lesions, several studies have attempted to correlate pancreatic cyst fluid CEA level and the presence of invasive carcinoma, with discordant results [ 17 , 18 ]. (gastrores.org)
  • The exocrine group is dominated by pancreatic adenocarcinoma (variations of this name may add "invasive" and "ductal"), which is by far the most common type, representing about 85% of all pancreatic cancers. (wikipedia.org)
  • The majority of pancreatic carcinomas are pancreatic ductal adenocarcinomas (PDAC), and the presence of non-invasive pancreatic intraepithelial neoplasia or intraductal papillary mucinous neoplasm, as an associated lesion, is considered important. (naramed-u.ac.jp)
  • These microscopic hyperplastic or grossly papillomatous lesions exhibit varying degrees of morphological atypia and may develop into invasive carcinomas. (naramed-u.ac.jp)
  • These results suggest that MUC1 and TJP2, the putative target molecules of miR-345, are critical in maintaining the invasive potential of pancreatic carcinoma cells, and regulating their expression may prevent the progression of non-invasive pancreatic intraductal lesions to invasive carcinomas. (naramed-u.ac.jp)
  • In spite of their aggressive biologic behavior, some ductal adenocarcinomas show bland nuclear features, making the distinction of benign lesion from an invasive carcinoma difficult, particularly on small biopsy specimens (Fig. 1). (coek.info)
  • IPMN accounts for less than 10% of all pancreatic neoplasms and particularly IPMNs with high-grade dysplasia are associated with a significantly increased risk of invasive PC [6]. (spg.pt)
  • As stated by William Brugge [7], the most important is to decide whether the guidelines should be designed to detect early neoplasia (eg, high grade dysplasia), as in Sendai-Fukuoka ones, or late (invasive) neoplasia, as in the case of AGA recommendations, taking also into account the patient's global health and the site of the cystic lesion. (spg.pt)
  • Whereas serous cystic neoplasms are benign, IPMNs as well as mucinous cystic neoplasms can progress to invasive adenocarcinoma and require surgical resection. (utoronto.ca)
  • Invasive mucinous adenocarcinoma is uncommon and usually arises in the background of benign or borderline tumors. (hindawi.com)
  • Evolving Trends Towards Minimally Invasive Surgery for Solid-Pseudopapillary Neoplasms. (ouhsc.edu)
  • An invasive breast adenocarcinoma characterized by the presence of tall columnar neoplastic cells that contain intracytoplasmic mucin. (nih.gov)
  • Uterine cancer is defined as any invasive neoplasm of the uterine corpus. (medscape.com)
  • Invasive neoplasms of the female pelvic organs account for almost 15% of all cancers in women. (medscape.com)
  • The data presented in this edition of Cancer Incidence in Five The CI5 data include all invasive malignant neoplasms and Continents (CI5) are mainly organised according to anatomical some non-invasive malignant neoplasms For most morphology site However, for some sites, the histological type of cancer codes, a fifth digit /1 or /2 automatically excludes the data entry. (who.int)
  • Cystic CEA level and the following pathologic variables: subtypes of IPMN, size of cystic lesion, presence of dysplasia or carcinoma, and main or branch duct involvement from 45 IPMN cases were analyzed. (gastrores.org)
  • Intraductal papillary mucinous neoplasm (IPMN) is a substantial subclass of pancreatic pathology, representing 20-50% of cystic pancreatic neoplasms [ 1 - 3 ]. (gastrores.org)
  • Cytology examination confirmed the diagnosis of IPMN with high-grade atypia and adenocarcinoma (Papanicolau Classification VI). (spg.pt)
  • Our patient presented with repeated attacks of acute pancreatitis, associated with MPD dilation, which raised the suspicion of a main duct IPMN, a lesion harboring a high risk of invasiveness. (spg.pt)
  • Mice were immunized with human pancreatic adenocarcinoma cells and monoclonal antibodies were screened against a panel of archived pancreatic tissue sections, including pancreatitis (23 cases), grade 1 IPMN (16 cases), grade 2 IPMN (9 cases), grade 3 IPMN (13 cases), and various grades of adenocarcinoma (17 cases). (elsevierpure.com)
  • One monoclonal antibody, human pancreatic cancer fusion 2 (HPC2) 1-B3, which specifically immunostained adenocarcinoma and all grades of IPMN, was isolated. (elsevierpure.com)
  • Accordingly, they are classified into three groups [main duct (MD), branch duct (BD), or mixed type (MT) IPMN] and can evolve as unifocal or multifocal lesions. (biomedcentral.com)
  • Even though such lesions should always be considered as precursor lesions for pancreatic ductal adenocarcinoma (PDAC), it remains unclear the proportion to which malignant transformation occurs, with reported rates varying between 18 and 25% for BD-IPMN and 60% and 70% for MD-IPMN [ 5 , 6 ]. (biomedcentral.com)
  • Due to the lack of knowledge regarding the natural history of these lesions, the management of IPMN remains controversial. (biomedcentral.com)
  • IPMN-LEARN: A linear support vector machine learning model for predicting low-grade intraductal papillary mucinous neoplasms. (cdc.gov)
  • Intraductal papillary mucinous neoplasm (IPMN) has a variety of histological and morphological appearances. (cancerindex.org)
  • The aim of this study was to elucidate the molecular basis of IPMN variation in different types of lesions. (cancerindex.org)
  • The availability of tools to interrogate the transcriptome and proteome, such as expression profiling, have identified a substantial library of products that could aid in distinguishing a well-differentiated pancreatic carcinoma from a benign pancreatic lesion.2 Many of these proteins can be detected immunohistochemically and are thus available to the practicing pathologist (Table 2).3 Some of these markers have been validated on biopsy specimens as well. (coek.info)
  • The purpose of this report is to describe the features of angiosarcoma arising in mucinous tumor that was misinterpreted as a benign vascular proliferation during the intraoperative consultation. (hindawi.com)
  • The large majority of mucinous tumors are benign and borderline tumors. (hindawi.com)
  • Although malignant tumors of the main papilla are more common, a number of benign neoplasms also may arise in the periampullary area, including benign adenomas (tubular and villous), lipomas, hamartomas, fibromas, and neurogenic tumors. (medscape.com)
  • Neoplasms that arise in the salivary glands are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes as seen in the image below. (medscape.com)
  • Patients with malignant lesions typically present after age 60 years, whereas those with benign lesions usually present when older than 40 years. (medscape.com)
  • [ 4 , 5 ] ) Benign neoplasms occur more frequently in women than in men, but malignant tumors are distributed equally between the sexes. (medscape.com)
  • Most series report that about 80% of parotid neoplasms are benign, with the relative proportion of malignancy increasing in the smaller glands. (medscape.com)
  • Section from right ovarian mass show a benign cystic tumour and the cyst wall lined by a single layer of mucinous epithelium. (radiologycases.my)
  • Active surveillance beyond 5 years is required for presumed branch-duct intraductal papillary mucinous neoplasms undergoing non-operative management. (jamanetwork.com)
  • This mucinous adenoma is lined by mucinous columnar neoplastic epithelium. (surgpath4u.com)
  • Undulating columnar epithelium is seen, but there are no complex papillary or cribriforming structures. (surgpath4u.com)
  • Although mucinous adenocarcinomas often demonstrates high-grade cytology, the tumor is often heterogeneous with foci of low-grade epithelium. (surgpath4u.com)
  • Cytologically low-grade mucinous neoplasms within the appendix appear to behave benignly, however, once mucin +/- adenomatous epithelium escapes from the confines of the appendix, morbidity and mortality increases significantly even if the cytology remains low-grade. (surgpath4u.com)
  • Evaluation of lesions is complicated by the fact that viscid mucin can dissect through the appendiceal wall, creating diverticuli and herniations of the epithelium that often mimic invasion. (surgpath4u.com)
  • In summary, Pai divided mucinous neoplasms into four groups using the following features: cytologic atypia of glandular epithelium, presence of extra-appendiceal cellular or acellular mucin (celluar mucin contains adenomatous epithelium whereas acellular mucin does not) and invasion (defined and infiltrative, jagged adenomatous epithelium beyond the muscularis mucosa of the appendix). (surgpath4u.com)
  • Low-grade mucinous neoplasms with high risk of recurrence (LG-HR): Same as LG-LR, but the extra-appendiceal mucin contains neoplastic epithelium. (surgpath4u.com)
  • Note that mucinous adenomas and mucinous cystadenomas most likely represent the same entity, as the neoplastic epithelium in a noncystic adenoma eventually generates enough mucin to cause luminal dilatation and thus, become a cystadenoma. (surgpath4u.com)
  • Histologically, IPMNs are lined by flat or papillary mucinous epithelium of gastric, intestinal, pancreatobiliary, or oncocytic type, exhibiting varying degrees of dysplasia, and surrounded by dense fibrotic stroma. (utoronto.ca)
  • Figure 2: (A) Papillary lesion with abnormally dispersed glandular structures (HEx50), (B) Dysplasia of the epithelium with extended, pseudostratified hyperchromatic nuclei of crowdy epithelial cells with mucin depletion (HEx200). (ispub.com)
  • The endocervix is lined by columnar mucinous epithelium and in continuity with vaginal mucosa, the ectocervix is lined by squamous epithelium. (cytojournal.com)
  • Seromucinous borderline tumors (SMBTs) are characterized by papillary architecture reminiscent of serous tumors but composed of mucinous epithelium similar to that of the endocervix. (hindawi.com)
  • Gastrointestinal stromal tumors formerly classified as either leiomyomas or leiomyosarcomas account for 2% of gastric neoplasms (see Gastric Stromal Tumors ). (medscape.com)
  • A small proportion of these tumors show large ducts lined by neoplastic cells, the so-called large-duct variant of adenocarcinoma. (coek.info)
  • The classification of mucinous tumors of the appendix is still in flux, however, the scheme proposed by Pai and colleagues focuses on a few key features (cytologic atypia, presence of cellular or acellular extra-appendiceal mucin and invasion) appears to have clear prognostic implications and stratifies the various subgroups into different survival rates. (surgpath4u.com)
  • Ovarian mucinous tumors may also cause pseudomyxoma peritonei, however, in most instances where both ovarian and appendiceal mucinous neoplasms are found in association pseudomyxoma peritonei, it is usually attributed to a primary appendiceal neoplasm. (surgpath4u.com)
  • Mucinous tumor is a common type of ovarian epithelial tumors. (hindawi.com)
  • Nonepithelial malignant neoplasms sometimes arise in mucinous tumors, typically as mural nodules. (hindawi.com)
  • Only 5 previous cases of angiosarcoma related to mucinous tumors have been reported [ 1 , 2 , 5 - 7 ]. (hindawi.com)
  • Papillary tumors are unusual entities, making up less than 5% of all new digestive tract neoplasms in the United States. (medscape.com)
  • Malignant papillary tumors have a more favorable course after resection when compared with pancreatic cancer. (medscape.com)
  • Lesions of endocrine origin have been termed carcinoid tumors. (medscape.com)
  • Although researchers have learned much from the study of this diverse group of tumors over the years, the diagnosis and treatment of salivary gland neoplasms remain complex and challenging problems for the head and neck surgeon. (medscape.com)
  • Salivary gland neoplasms make up 6% of all head and neck tumors. (medscape.com)
  • Almost half of all submandibular gland neoplasms and most sublingual and minor salivary gland tumors are malignant. (medscape.com)
  • Carcinoma of cervix is classified as per the WHO classification into primary tumors which are predominantly epithelial tumors, mesenchymal tumors and tumor like lesions, mixed epithelial stromal tumors, melanocytic, germ cell, and lymphoid tumors. (cytojournal.com)
  • Aim: The aim of this study is to investigate the DNA ploidy and S-Phase Fraction (SPF) of some Salivary Gland Tumors (SGTs) in Egyptian patients and to investigate the correlation between these two biological parameters and the presumptive behavior of these neoplasms. (researchgate.net)
  • There was no transitional lesion between the two tumors. (hindawi.com)
  • SMBTs have been considered a subset of mucinous tumors and account for 15% of all mucinous borderline tumors [ 1 ]. (hindawi.com)
  • A few studies have reported tumors coexisting with SMBTs, such as endometrioid adenocarcinoma [ 4 ] and squamous cell carcinoma [ 5 ]. (hindawi.com)
  • We suggest that these ovarian tumors and colonic lesions were also associated with separate endometriotic foci. (hindawi.com)
  • Thirteen individuals with FPC (6.1%) underwent surgical resection for a suspected PRL, but only four (1.9%) had high-risk lesions (ie, high-grade intraductal papillary mucinous neoplasms or grade 3 pancreatic intraepithelial neoplasms). (medscape.com)
  • Distal Pancreatectomy with En Bloc Celiac Axis Resection After Neoadjuvant Therapy for Locally Advanced Pancreatic Adenocarcinoma. (columbiasurgery.org)
  • Surprisingly, 23 cysts (5%) were found to be ductal adenocarcinoma, whereas 45 patients (9%) underwent a pancreatic resection for a non-neoplastic condition. (univr.it)
  • In 1946, Waugh and Clagett described a formal en-bloc resection of the gallbladder with the common bile duct (CBD), gastric antrum, duodenum, and pancreatic head performed as a one-stage procedure, which we recognize today as the classic pancreaticoduodenectomy. (medscape.com)
  • Although innumerable details of pancreaticoduodenectomy yield to continued innovation, a comprehensive discussion of intraoperative variants (ie, duct to mucosa vs invagination of the pancreaticojejunal anastomosis, diverse approaches to vein resection and reconstructions, nuances of each enteric anastomosis, and modifications of Roux-en-Y reconstructions, to name a few) is beyond the scope of this article. (medscape.com)
  • The patient underwent surgery and local resection of ampullary neoplasm was performed. (ispub.com)
  • Since Halsted (2) described the first local resection of ampullary lesions in 1899, the authors still debate on adequate surgery in this disease. (ispub.com)
  • The study also reported that recurrence risk factors for these lesions included positive and uncertain resection margins, as well as younger age at diagnosis. (medscape.com)
  • Histologic changes caused by injection of a novel submucosal lifting agent for endoscopic resection in GI lesions. (uchicago.edu)
  • A nodular lesion was found at the serosa of the sigmoid colon during the surgery, and a partial sigmoid colon resection was performed. (hindawi.com)
  • Purpose Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis. (medscape.com)
  • The aim of this study was to assess whether surveillance aids detection of early-stage PDAC or precursor lesions (PRLs) and improves the prognosis. (medscape.com)
  • Surveillance of these high-risk groups may lead to early detection of PDAC or detection of precursor lesions (PRLs), allowing curative surgical treatment. (medscape.com)
  • Immunological consequences of endoscopic ultrasound (EUS)-local thermal ablation (LTA) for pancreatic ductal adenocarcinoma (PDAC) have not been extensively assessed. (bvsalud.org)
  • INTRODUCTION: Only a small number of risk factors for pancreatic ductal adenocarcinoma (PDAC) has been established. (bvsalud.org)
  • PDAC, pancreatic ductal adenocarcinoma. (jamanetwork.com)
  • Risk factors for Rem-Panc recurrence were reported to be the presence of high-grade dysplasia in resected specimens, positive surgical margins, and a family history of pancreatic ductal adenocarcinoma (PDAC). (biomedcentral.com)
  • Cervical Cancer Screening Using Primary High-Risk HPV (hrHPV) Versus Cotesting: Implications for hrHPV-Negative Patients with High Grade Squamous Epithelial Lesion Manrai P, Levi A, Sun T, Wang M, Cai G , Abi-Raad R. Cervical Cancer Screening Using Primary High-Risk HPV (hrHPV) Versus Cotesting: Implications for hrHPV-Negative Patients with High Grade Squamous Epithelial Lesion. (yale.edu)
  • In the remaining cases, angiosarcoma was associated with ovarian teratoma or epithelial neoplasm [ 2 , 4 ]. (hindawi.com)
  • Most of the cervical epithelial neoplasms and their precursors occur at the squamocolumnar junction or within the transformation zone. (cytojournal.com)
  • The typical gross appearance of these tumours is similar to that of other epithelial lesions, with variable cystic and solid components. (radiologycases.my)
  • However, adenocarcinomas of the lung, and occasional breast, transitional cell and pancreatic carcinomas had moderate or high levels of HE4 expression. (nature.com)
  • 18 With the exception of the ovarian neoplasms, the same carcinomas analyzed for gene expression were also examined for HE4 by immunohistochemistry on tissue microarrays (see below). (nature.com)
  • Mucinous breast carcinomas lack PIK3CA and AKT1 mutations. (nih.gov)
  • Mucinous (so-called colloid) carcinomas of lung. (nih.gov)
  • Approximately eighty percent of endometrial carcinomas are endometrioid adenocarcinomas. (medscape.com)
  • Other histologic subtypes include adenosquamous, clear cell, and papillary serous carcinomas. (medscape.com)
  • 2 Moreover, up to 10% of patients with intraductal papillary mucinous neoplasms (IPMNs), which are pre-malignant lesions, may be initially incorrectly diagnosed with CP. (practicalgastro.com)
  • A 35 cm right ovarian mass submitted for intraoperative consultation was a multicystic mucinous tumor with an 8 cm area of hemorrhagic lesion between cystic locules. (hindawi.com)
  • The frozen section diagnosis was at least mucinous borderline tumor. (hindawi.com)
  • A macroscopic hemorrhagic area in an ovarian mucinous tumor should be evaluated with care, and the possibility of angiosarcoma should be borne in mind. (hindawi.com)
  • The frozen section diagnosis was at least mucinous borderline tumor, pending adequate tissue sampling for permanent sections to rule out mucinous adenocarcinoma. (hindawi.com)
  • Chapter 32 Gastrointestinal Cancers DIAGNOSIS TREATMENT DIAGNOSITC IMAGING MEDICATIONS CT scan, MRI, labeled somatostatin receptor-based diagnostic imaging ▪ Localization, TNM staging ▪ Presence of hepatic lesions SURGERY Endoscopy with biopsy ▪ Tumor visualization ▪ Histopathological analysis, grading ▪ Somatostatin analogues suppress tumor proliferation, decrease symptoms ▪ Surgical removal of tumor LAB RESULTS ▪ 5-hydroxyindoleacetic acid, chromogranin Figure 32.2 Gross pathology of carcinoid tumor of the terminal ileum. (osmosis.org)
  • The most common tumor of the parotid gland is the pleomorphic adenoma , which represents about 60% of all parotid neoplasms, as seen in the table below. (medscape.com)
  • No apparent transitional lesions were noted between the different tumor components. (hindawi.com)
  • OBJECTIVES: Repeated endoscopic ultrasound (EUS)-guided tissue acquisition represents the standard practice for solid pancreatic lesions after previous nondiagnostic or inconclusive results. (bvsalud.org)
  • Over the past decade, the role of the pathologist has changed as well, with the widespread availability of endoscopic ultrasound-guided fine-needle aspiration biopsy, a technique that has allowed for sampling of these lesions with relatively little morbidity and mortality. (coek.info)
  • Background and study aims: Endoscopic ultrasound (EUS) with fine-needle aspiration (FNA) of pancreatic cystic lesions (PCL) is flawed by inadequate diagnostic yield. (elsevierpure.com)
  • Preoperative endoscopic tattooing of pancreatic body and tail lesions decreases operative time for laparoscopic distal pancreatectomy. (ouhsc.edu)
  • Current guidelines for the management of pancreatic cystic neoplasms are based on the assumption that these lesions can be classified correctly on the basis of features of cross-sectional imaging. (univr.it)
  • Diagnosis and management of pancreatic cystic neoplasms: current evidence and guidelines. (jamanetwork.com)
  • This procedure is also the primary method for obtaining a tissue diagnosis of suspected lesions. (medscape.com)
  • Increased levels of serum carbohydrate antigen (CA)19-9 resulted as risk factors for an incorrect diagnosis as well as for a final diagnosis of a ductal adenocarcinoma. (univr.it)
  • Neoplastic lesions of the ampulla vary between 0.063 and 0.21% on autopsy investigations but the frequency of their diagnosis is increasing because of the extensive use of flexible endoscopy (1). (ispub.com)
  • Cytologic diagnosis of papillary carcinoma of the breast in needle aspirates. (nih.gov)
  • Mucinous adenocarcinoma and signet-ring cell carcinoma are rarer variants with grave prognoses. (smjonline.org)
  • Mucinous breast carcinoma with tall columnar cells. (nih.gov)
  • Mucinous metaplasia of breast carcinoma with macrocystic transformation resembling ovarian mucinous cystadenocarcinoma in a case of synchronous bilateral infiltrating ductal carcinoma. (nih.gov)
  • PATHOLOGY Ductal adenocarcinomas are firm to hard mass lesions that are often poorly defined grossly. (coek.info)
  • Histologically, most ductal adenocarcinomas are composed of glandlike structures embedded in an abundant desmoplastic stroma. (coek.info)
  • In contrast, HPC2 1-B3 immunostained the cytoplasm and luminal surface of all 16 well- to moderately differentiated pancreatic ductal adenocarcinomas. (elsevierpure.com)
  • Laparoscopic Spleen-Preserving Total Pancreatectomy for a Main-Duct Intraductal Papillary Mucinous Neoplasm. (ouhsc.edu)
  • During the diagnostic workup for pancreatic cysts, CEA is often utilized to distinguish those pancreatic cystic lesions that are likely to be mucinous [ 13 - 16 ]. (gastrores.org)
  • Increased detection of pancreatic cysts provides an opportunity to diagnose pancreatic malignancy at an early, curable stage yet also increases the potential to over-treat clinically insignificant lesions. (ucsf.edu)
  • The UCSF Pancreatic Cystic Lesions Registry (PANC Cyst) will facilitate work to improve clinical care and understanding of pancreatic cysts by prospective follow-up of patients with cystic lesions, especially the diagnostically challenging small cysts, to identify factors related to cyst formation and progression to malignancy. (ucsf.edu)
  • its cut surface was characterized by multiple cysts with mucinous, faintly brown fluid (Figure 1(a) ). (hindawi.com)
  • Many of the cysts and the low papillary growth lesions were lined by tall columnar mucinous or cuboidal ciliated serous cells (Figure 2(b) ). (hindawi.com)
  • Stage 2 assessed whether the specific criteria defined in Stage 1 could identify pancreatic cystic neoplasms (PCN) including intraductal papillary mucinous neoplasms, mucinous cystic adenoma, or adenocarcinoma in an off-line blinded consensus review. (elsevierpure.com)
  • Adenocarcinoma of the stomach constitutes 90-95% of all gastric malignancies. (medscape.com)
  • Preoperative workup was reviewed to identify diagnostic pitfalls and potential risk fact ins for incorrect preoperative characterization of cystic lesions presumed to be neoplastic. (univr.it)
  • Interobserver variability in intraductal papillary mucinous neoplasm subtypes and application of their mucin immunoprofiles. (uchicago.edu)
  • The lower anogenital squamous terminology (LAST), an acronym for LAST, incorporates the low- and high-grade squamous intraepithelial lesion (HSIL) terminology. (cytojournal.com)
  • No benefit of addition of other biomarkers like p63 or ki67 is found in problem-solving in differentiation of HSIL from mimics or low-grade squamous intraepithelial lesion. (cytojournal.com)
  • Subsequently, HPC2 1-B3 was evaluated in a retrospective series of 31 fine-needle aspiration (FNA) biopsies from clinically suspicious pancreatic lesions that had long-term clinical follow-up. (elsevierpure.com)
  • Adenocarcinoma of the stomach is subclassified according to histologic description as follows: tubular, papillary, mucinous, or signet-ring cells, and undifferentiated lesions. (medscape.com)
  • Pai and colleagues (2009) studied 116 cases of appendiceal mucinous neoplasms and derived a concise set of histologic features with important prognostic implications. (surgpath4u.com)
  • Pancreatic ductal adenocarcinoma with autoimmune pancreatitis-like histologic and immunohistochemical features. (uchicago.edu)
  • METHODS: Consecutive patients undergoing rEUS-FNB for solid pancreatic lesions at 23 Italian centers from 2019 to 2021 were retrieved. (bvsalud.org)
  • Note that this lining is adenomatous , which separates this mucinous adenomas from hyperplastic lesions (which do NOT exhibit any dysplasia). (surgpath4u.com)
  • Long-term risk of pancreatic malignancy in patients with branch duct intraductal papillary mucinous neoplasm in a referral center. (jamanetwork.com)
  • Endometrial adenocarcinoma is the most common gynecologic malignancy in the United States. (medscape.com)
  • It is important to note, however, that mucinous neoplasms low-grade cytology may demonstrate invasion elsewhere and thus is actually a mucinous adenocarcinoma . (surgpath4u.com)
  • This document summarizes recommendations for the clinical and imaging work-up of pancreatic and biliary tract lesions along with indications for cytologic study of these lesions. (cytojournal.com)
  • Additionally, we found typical endometriosis and an atypical endometrial nodular lesion in the colon in this patient. (hindawi.com)
  • Laparoscopic pancreaticoduodenectomy: changing the management of ampullary neoplasms. (ouhsc.edu)
  • It is considered the second commonest malignant ovarian neoplasm. (radiologycases.my)
  • This exam revealed a lesion in the pancreatic head along with an atrophic pancreatic parenchyma, with lobularity, hyperechoic foci and stranding. (spg.pt)
  • In 1937, Brunschwig extended the indications for pancreaticoduodenectomy by performing the operation for pancreatic head lesions. (medscape.com)
  • Artificial intelligence for the detection of pancreatic lesions. (cdc.gov)
  • Several other types of cancer, which collectively represent the majority of the non-adenocarcinomas, can also arise from these cells. (wikipedia.org)
  • Among salivary gland neoplasms, 80% arise in the parotid glands, 10-15% arise in the submandibular glands, and the remainder arise in the sublingual and minor salivary glands. (medscape.com)
  • In three cases which initially were taken for pleomorphic adenomas by routine histological examination, aneuploid cell populations exposed by DNA flow cytometric analysis gave rise to a closer inspection of the suspect lesions. (researchgate.net)
  • Primary mammary mucinous cystadenocarcinoma: cytological and histological findings. (nih.gov)
  • The main structure of the histological grouping is that Morphology codes specific types of malignant neoplasms are listed as wel as Grouping of morphological codes presents several difficulties. (who.int)
  • Gemcitabine combined with oxaliplatin (GEMOX) in advanced biliary tract adenocarcinoma: a GERCOR study. (cancercentrum.se)
  • We report a case of mucin-secreting biliary neoplasm of the ampulla of Vater diagnosed peroperatively because of unsuccessful endoscopy due to pyloric stenosis, and successfully treated with transduodenal local excision. (ispub.com)