AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsHumanitiesInformation ScienceHealth CareGeographicals
Carcinoma, PapillaryThyroid NeoplasmsCarcinomaAdenocarcinoma, FollicularCarcinoma, Papillary, FollicularPapilloma, IntraductalThyroidectomyThyroglossal CystAdenocarcinoma, PapillaryCarcinoma, Squamous CellThyroid GlandCarcinoma, HepatocellularCystadenocarcinoma, PapillaryThyroid NoduleAdenomaCarcinoma, MedullaryImmunohistochemistryBiopsy, Fine-NeedleTumor Markers, BiologicalProto-Oncogene Proteins c-retGoiter, NodularCarcinoma in SituMixed Tumor, MalignantStruma OvariiNeoplasms, Multiple PrimaryThyroid DiseasesBreast Neoplasms, MaleCarcinoma, Intraductal, NoninfiltratingKeratin-7UkraineAdenoma, OxyphilicBiopsy, NeedleCystadenocarcinoma, SerousGoiterGalectin 3Neoplasm InvasivenessLymphatic MetastasisLiver NeoplasmsBranchiomaRadioactive Hazard ReleaseThyroglobulinBreast NeoplasmsGene Expression Regulation, NeoplasticCarcinoma, Ductal, BreastChernobyl Nuclear AccidentCarcinoma, Basal CellAdenocarcinomaPrognosisBile Ducts, ExtrahepaticKeratinsPapillomaThyroiditis, AutoimmuneKeratin-6Iodine RadioisotopesNeoplasm StagingKeratin-8Tumor Cells, CulturedHistocytochemistryUterine NeoplasmsRetrospective StudiesDNA, NeoplasmCarcinoma, Transitional CellCell Line, TumorImmunoenzyme TechniquesBile Duct NeoplasmsNeoplasms, Radiation-InducedRNA, MessengerProto-Oncogene Proteins B-rafCarcinoma, BronchogenicHashimoto DiseaseNuclear Receptor CoactivatorsReverse Transcriptase Polymerase Chain ReactionUrinary Bladder NeoplasmsCarcinoma, Adenoid CysticGene RearrangementAntigens, NeoplasmRNA, NeoplasmOvarian NeoplasmsCarcinoma, Small CellSensitivity and SpecificityReceptor Protein-Tyrosine KinasesCarcinoma, LobularKeratin-5CystsKeratin-18HyperplasiaSodium Pertechnetate Tc 99mNeckCarcinoma, NeuroendocrineCytodiagnosisNasopharyngeal NeoplasmsNeoplasm Recurrence, LocalThyroiditisKi-67 AntigenRadionuclide ImagingBreastIncidental FindingsMicroscopyCalcitoninMastectomy, Modified Radical
Basal carcinomaSquamous cell carcinomasTumorTreatment of verrucous carcinomaSituCuniculatumNeoplasmsTerm verrucous carcinomaLesionsLarynxBasaloid squamous cell carcLesionInvasiveWartyTumorsBuccal mucosaOral florid papillomatosisLymphocytes and plasma cellsCutaneousAdenosquamous carcinomaUncommonDysplasiaAckermanDermisProjectionsOccurMucosaWartsCervixNoduleEPITHELIAL CELLSIrregularPredominantlyMetastasisClinicalHead and neckPlaqueOropharynx
Basal carcinoma1
  • mucinous, villoglandular, endometrioid) Clear cell adenocarcinoma Serous carcinoma Adenosquamous carcinoma Glassy cell carcinoma Adenoid cystic carcinoma Adenoid basal carcinoma Small cell carcinoma Undifferentiated carcinoma Cancers can be histopathologically graded as follows: GX: Grade cannot be assessed G1: Well differentiated G2: Moderately differentiated G3: Poorly or undifferentiated For microinvasive disease, clinicians should collect a specimen using a loop electrosurgical excision procedure (LEEP) or a cone biopsy. (wikipedia.org)
Squamous cell carcinomas4
  • It accounts for 5% of all intraoral squamous cell carcinomas 5 . (ispub.com)
  • Therein, penile squamous cell carcinomas were divided into two groups based on the pathogenesis, namely HPV-associated and HPV-independent. (bvsalud.org)
  • It is intended to validate the WHO classification for these tumors and to establish prognostic variables of the variants of squamous cell carcinomas. (fapesp.br)
  • 90%) are squamous cell carcinomas (SCCs) with an incidence of 1 to 3/100,000 in the United States and Europe per year. (entokey.com)
Tumor9
  • Carcinoma of cervix is classified as per the WHO classification into primary tumors which are predominantly epithelial tumors, mesenchymal tumors and tumor like lesions, mixed epithelial stromal tumors, melanocytic, germ cell, and lymphoid tumors. (cytojournal.com)
  • Oral, laryngeal, pharyngeal, and esophageal lesions of this type are generally known as a verrucous carcinoma or an Ackerman tumor. (medscape.com)
  • Verrucous carcinoma of both the skin and the mucosa is an uncommon low-grade squamous cell carcinoma that is clinically evident as a slowly but relentlessly enlarging warty tumor, histologically characterized by local invasion with minimal dysplasia, if any, and biologically characterized by a low incidence of metastases. (medscape.com)
  • In 1948, Lauren V. Ackermann first described this neoplasm of the oral mucous membrane, which is now also know as Verrucous Carcinoma of Ackermann or Ackermann's tumor. (ispub.com)
  • The development of verrucous carcinoma from proliferative lesions makes it likely that the tumor develops from a benign precursor. (ispub.com)
  • A papillary hidradenoma, also hidradenoma papilliferum, is a sharply circumscribed nodule or benign tumor of the apocrine gland usually found on the de catre uterul marit a plamanilor si umflarea gleznelor, vulvei si squamous cell papilloma nhs abdomenului inferior. (evenimente-corporate.ro)
  • Daum O, Ferdova E, Kural T, Grossmann P, Nemcova J, Mukensnabl P, Michal M. Pancreatic undifferentiated carcinoma with osteoclast-like giant cells masquerading as (extra)gastrointestinal stromal tumor: potential diagnostic pitfall. (patologie.cz)
  • A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane. (bvsalud.org)
  • Invasive carcinoma eliminates the regular architecture and can include lympho-vascular space invasion, neurotropism, and infiltration of other tissue components such as muscle or cartilage, demonstrating aggressive behavior of the tumor. (entokey.com)
Treatment of verrucous carcinoma1
Situ2
Cuniculatum3
  • Whether the carcinoma occur in the upper aerodigestive tract (verrucous carcinoma), on the genitalia (condyloma acuminatum), or on extremities (carcinoma cuniculatum), they are essentially the same neoplasm with slow growing, locally invasive and nonmetastasizing behavior 3 . (ispub.com)
  • Carcinoma Cuniculatum: Usefulness of Radiological Assessment. (units.it)
  • when verrucous carcinoma involves the plantar surface of the foot, it is named carcinoma cuniculatum (CC). Metastasis from CC is rare, although it can invade deep into the soft tissues and can extend to tendons, muscles, or bone. (units.it)
Neoplasms1
  • The most common benign and malignant neoplasms arising in this disorder include trichilemmoma, syringocystadenoma papilliferum, keratoacanthoma, apocrine cystadenoma and basal cell carcinoma. (ijcrr.com)
Term verrucous carcinoma4
  • [ 2 ] described oral verrucous carcinoma and coined the term verrucous carcinoma. (medscape.com)
  • Although the term verrucous carcinoma followed by its anatomical site would be the most comprehensive name, the historical name justifiably favors honoring 2 eminent physicians, Abraham Buschke (1868-1943) of Berlin and Ackerman (1905-1993). (medscape.com)
  • Ackerman used the term verrucous carcinoma to denote the concept of a locally aggressive exophytic low-grade squamous cell carcinoma with little metastatic potential. (medscape.com)
  • Verrucous carcinoma is an uncommon but distinct variety of well differentiated squamous cell carcinoma first delineated by Ackerman in 1948 3 .The term verrucous carcinoma refers to those exophytic mucosal or cutaneous squamous tumors that are heaped above the epithelial surface with a papillary micronodular surface and pushing margins 4 .Predominantly being a squamous mucosal lession, verrucous carcinoma may also be found on cutaneous surfaces. (ispub.com)
Lesions3
  • See also Verrucous Carcinoma , Proliferative Verrucous Leukoplakia , Cancers of the Oral Mucosa , and Smokeless Tobacco Lesions . (medscape.com)
  • Precursor lesions of squamous cell carcinoma underwent substantial modifications in the WHO classification 2016 as well, and remain unchanged in WHO classification 2022. (bvsalud.org)
  • Among the IDC (NOS) lesions, six cases of grade III breast carcinoma exhibited a positive immunohistochemical reaction, the staining index of which varied from 2-6. (ijpmonline.org)
Larynx2
  • Oral florid papillomatosis is a type of verrucous carcinoma (VC) that is clinically evident as multiple squamous papillary nodules in the oral cavity and, less commonly, in the larynx, the pharynx, the esophagus, the middle ear, the maxillary antrum, the nasal fossa, and the bronchus. (medscape.com)
  • Spindle cell carcinoma of the larynx. (nih.gov)
Basaloid squamous cell carc1
Lesion5
  • Verrucous carcinoma (VC) was first described in 1948 as a slow-growing exophytic and papillary lesion [ 1 ]. (jwmr.org)
  • The fully developed carcinoma in an exophytic gray to red bulky lesion with a rough, shaggy, papillomatous surface 3 . (ispub.com)
  • Histological data were also obtained and blindly re-examined.Results: For instance, a biopsy performed on a lingual ulcer has a strong predicting association with a carcinoma, whereas a biopsy on a white lesion predicts for a leukoplakia or oral lichen planus. (ncl.ac.uk)
  • Moreover, a biopsy of erosion is representative of bullous diseases, whereas a biopsy on a verrucous-papillary lesion is significant for fibroma. (ncl.ac.uk)
  • Lesion formed an irregular nodule during puberty and progressed to a verrucous plaque, on right side, since one month. (ijcrr.com)
Invasive1
Warty1
  • Variants of squamous cell carcinoma, namely basaloid, papillary-basaloid, warty, warty-basaloid, clear cell and lymphoepithelioma-like carcinomas are not recognized as distinctive variants of HPV-associated group anymore. (bvsalud.org)
Tumors2
  • Squamous cell carcinoma (SCC) in various morphological forms needs to be separated from other epithelial tumors for treatment modality selection. (cytojournal.com)
  • In late childhood and early adulthood, there is a significant risk of developing secondary tumors, the most common of which are syringocystadenoma papilliferum and basal cell carcinoma. (ijcrr.com)
Buccal mucosa2
  • Carcinoma of the buccal mucosa is relatively uncommon in North America compared with other oral cavity cancers such as carcinomas of the tongue or floor of the mouth. (medscape.com)
  • Early oral squamous cell carcinoma in the buccal mucosa arising from leukoplakia. (medscape.com)
Oral florid papillomatosis1
  • Oral florid papillomatosis is best defined as a type of verrucous carcinoma, although some consider it a separate entity. (medscape.com)
Lymphocytes and plasma cells1
  • The papillary dermis showed chronic inflammatory infiltrates composed predominantly of lymphocytes and plasma cells admixed with few eosinophils ( Figure 2 ). (iranjd.ir)
Cutaneous4
Adenosquamous carcinoma1
Uncommon1
  • The clustered vesicles characteristically cover a surface area greater than a square centimeter, and it is uncommon for vesicular areas to form plaques or undergo verrucous changes. (astrocyte.in)
Dysplasia1
  • Verrucous carcinoma is a rarely occurring, low-grade variant of squamous cell carcinoma, slow-growing verrucous and with minimal dysplasia. (units.it)
Ackerman2
  • Buschke was a legendary professor of dermatology, and Ackerman, the renowned professor of pathology, developed the concept of verrucous carcinoma. (medscape.com)
  • Ackerman first recognized verrucous carcinoma as a distinct entity in 1948. (ispub.com)
Dermis2
  • c) Papillary dermis showing capillary-sized blood vessels and inflammatory infiltrates (H&E 4X). (iranjd.ir)
  • Dilated thin-walled lymphatic vessels stand out in the papillary dermis, associated with surrounding lymphocytic infiltrates and overlying epidermal acanthosis (H and E, original magnification ×40). (astrocyte.in)
Projections2
  • blunt papillary projections of well-differentiated epithelium, little atypia, with nonreactive edematous stroma [Figure 1e]. (units.it)
  • Papillary projections into the cystic invagination were evident. (ijcrr.com)
Occur1
  • Furthermore, carcinomas occur in the majority of cases on the lingual edge or pelvis, oral lichen planus is mainly seen on the edge, and fibromas mostly on the lingual tip.Conclusions: The high frequency of tongue involvement of such different diseases emphasizes the importance of histological characterization and that some diseases occur more frequently than others, with a peculiar clinical aspect and a more common area. (ncl.ac.uk)
Mucosa1
  • With respect to the upper aero digestive tract, where the verrucous carcinoma most often arises, the oral cavity, particularly the cheek mucosa, gingivae and retromolar areas, remains the most common site of origin 4 . (ispub.com)
Warts1
  • Still others consider it a disease on a continuum between viral warts and verrucous carcinoma, rather than a verrucous carcinoma per se. (medscape.com)
Cervix3
  • citation needed] The carcinoma is confined to the surface layer (cells lining) of the cervix. (wikipedia.org)
  • The carcinoma has grown into the cervix, but has not spread beyond it (extension to the corpus would be disregarded). (wikipedia.org)
  • Carcinoma cervix is not the only cancer caused by HPV. (cytojournal.com)
Nodule1
  • Local examination showed a pigmented, non tender, verrucous nodule in right nipple areolar complex, measuring 3.5x2.5x2cm. (ijcrr.com)
EPITHELIAL CELLS1
Irregular1
  • In most cases, it is asymptomatic and characterized by a well demarcated elevation with irregular or papillary surface. (bvsalud.org)
Predominantly1
  • Dense mononuclear inflammatory infiltrate, predominantly plasma cells were seen in the papillary core and around the cyst wall. (ijcrr.com)
Metastasis1
  • Kasuganti D, Cimbaluk D, Gattuso P. Lymph node metastasis of large-cell carcinoma of the lung in a seventeen-year-old patient: diagnosis by fine-needle aspiration. (rush.edu)
Clinical3
  • The role of induction chemotherapy in the treatment of advanced stage head and neck squamous cell carcinoma is controversial and is often recommended for clinical trials. (medscape.com)
  • The typical microscopic section shows a well-differentiated typical squamous cell carcinoma with verrucous clinical morphology. (medscape.com)
  • From the clinical point of view, verruciform xanthoma is characterized by a well delimited rough or papillary elevation and may be depressed or ulcerated at the center 4,6-7 . (bvsalud.org)
Head and neck1
  • Chemotherapy given concomitantly with radiation therapy for the treatment of nonoperative head and neck squamous cell carcinoma has an overall and disease-free survival rate greater than that of radiation therapy alone. (medscape.com)
Plaque1
  • This verrucous plaque involved the proximal nail fold, nail matrix, nail bed, and hyponychium. (jwmr.org)
Oropharynx1
  • Verrucous carcinoma usually appears in 3 main sites: the oropharynx, the genital tract, and the soles of the feet. (medscape.com)