• Adjuvant radiotherapy in the treatment of invasive intraductal papillary mucinous neoplasm of the pancreas: an analysis of the surveillance, epidemiology, and end results registry. (duke.edu)
  • BACKGROUND: Management and outcomes of patients with invasive intraductal papillary mucinous neoplasm (IPMN) of the pancreas are not well established. (duke.edu)
  • To study the relationship between carcinoembryonic antigen (CEA) level, intraductal papillary mucinous neoplasm (IPMN) subtype, and the presence of invasive carcinoma. (gastrores.org)
  • Intraductal papillary mucinous neoplasm (IPMN) is a substantial subclass of pancreatic pathology, representing 20-50% of cystic pancreatic neoplasms [ 1 - 3 ]. (gastrores.org)
  • Intraductal papillary mucinous neoplasm (IPMN) is a non-invasive mucin-producing neoplasm of the pancreas arising from the main pancreatic duct or side-branches. (utoronto.ca)
  • The majority of pancreatic carcinomas are pancreatic ductal adenocarcinomas (PDAC), and the presence of non-invasive pancreatic intraepithelial neoplasia or intraductal papillary mucinous neoplasm, as an associated lesion, is considered important. (naramed-u.ac.jp)
  • A six-month follow-up MRI scan was recommended for patients with nonspecific findings or if a tumor was found within the pancreatic ducts (known as intraductal papillary mucinous neoplasia), but no surgery was necessary. (scanforlife.co.za)
  • una neoplasia mixta en el cuerpo y cola pancreática. (bvsalud.org)
  • A two-tiered nomenclature system has been accepted for non-invasive HPV associated squamous proliferations of cervix and lower anogenital tract. (cancer.org.au)
  • The term 'microinvasive carcinoma' is no longer recommended, and the term 'superficially invasive squamous cell carcinoma' (SISCCA) should be used instead. (cancer.org.au)
  • A few studies have reported tumors coexisting with SMBTs, such as endometrioid adenocarcinoma [ 4 ] and squamous cell carcinoma [ 5 ]. (hindawi.com)
  • Squamous cell carcinoma, adenocarcinoma and small cell carcinoma accounted for 2.7, 1.8 and 0.6% of all bladder tumours, respectively. (hku.hk)
  • In addition of the categories of squamous dysplasia and carcinoma in situ , two additional lesions were added to the group of pre-invasive lesions: atypical adenomatous hyperplasia (AAH) and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH). (ersjournals.com)
  • A mixed adenocarcinoma and squamous cell or epidermoid carcinoma. (bvsalud.org)
  • Cytokeratins can be used to detect small nodal metastases or subtle invasive carcinomas such as invasive lobular carcinomas. (bmj.com)
  • These microscopic hyperplastic or grossly papillomatous lesions exhibit varying degrees of morphological atypia and may develop into invasive carcinomas. (naramed-u.ac.jp)
  • These results suggest that MUC1 and TJP2, the putative target molecules of miR-345, are critical in maintaining the invasive potential of pancreatic carcinoma cells, and regulating their expression may prevent the progression of non-invasive pancreatic intraductal lesions to invasive carcinomas. (naramed-u.ac.jp)
  • Approximately eighty percent of endometrial carcinomas are endometrioid adenocarcinomas. (medscape.com)
  • Other histologic subtypes include adenosquamous, clear cell, and papillary serous carcinomas. (medscape.com)
  • Seromucinous borderline tumors (SMBTs) are characterized by papillary architecture reminiscent of serous tumors but composed of mucinous epithelium similar to that of the endocervix. (hindawi.com)
  • Nuclear stratification was noted, but no invasive growth was apparent in these cystic tumors. (hindawi.com)
  • The tumors showed glandular proliferation or small nests with invasive growth (Figure 2(d) ). (hindawi.com)
  • Adenoid cystic carcinoma, adenocarcinoma and expleomorphic adenoma were observed as primary malignant tumors. (selcukmedj.org)
  • CONCLUSION: On propensity-score-adjusted analysis, adjuvant RT was associated with improved survival in selected subsets of patients with invasive IPMN, particularly those with T3/T4 tumors and LN involvement. (duke.edu)
  • Papillary tumors are unusual entities, making up less than 5% of all new digestive tract neoplasms in the United States. (medscape.com)
  • Malignant papillary tumors have a more favorable course after resection when compared with pancreatic cancer. (medscape.com)
  • Primary therapy for epithelioid tumors is thyroidectomy, but large, invasive, or metastatic varieties warrant adjuvant radiotherapy. (eyerounds.org)
  • In previous FIGO staging reviews, stage I included all tumors confined to the cervix (FIGO 1950 and 1971), later subdividing stage I into IA (preclinical invasive carcinoma) and IB (FIGO 1974). (bmj.com)
  • Adenocarcinomas, which may occur as primary tumors or rarely reflect metastasis from intestinal carcinoma. (msdmanuals.com)
  • The nomenclature addresses pre-invasive mucosal lesions and early invasive mucosal lesions. (cancer.org.au)
  • Microscopically, multiple cystic lesions or exophytic growth with low papillary lesions was identified in the ovaries (Figure 2(a) ). (hindawi.com)
  • Many of the cysts and the low papillary growth lesions were lined by tall columnar mucinous or cuboidal ciliated serous cells (Figure 2(b) ). (hindawi.com)
  • In an attempt to identify pancreatic cystic lesions with an increased risk of associated invasive adenocarcinoma, carcinoembryonic antigen (CEA) level has emerged over the last few decades as a tool to assess pancreatic cystic fluid pre-operatively. (gastrores.org)
  • In addition to CEA being used to stratify mucinous vs. non-mucinous lesions, several studies have attempted to correlate pancreatic cyst fluid CEA level and the presence of invasive carcinoma, with discordant results [ 17 , 18 ]. (gastrores.org)
  • Myoepithelial markers, such as smooth muscle actin, smooth muscle myosin heavy chain and p63, are useful for distinguishing invasive carcinoma from sclerosing lesions and ductal carcinoma in situ (DCIS), and in the classification of papillary lesions. (bmj.com)
  • An endolymphatic sac tumor (ELST) is a very uncommon papillary epithelial neoplasm arising within the endolymphatic sac or endolymphatic duct. (wikipedia.org)
  • The ELST has been referred to as adenocarcinoma of endolymphatic sac, Heffner tumor, papillary adenomatous tumor, aggressive papillary adenoma, invasive papillary cystadenoma, and papillary tumor of temporal bone. (wikipedia.org)
  • The tumor is arranged as simple, broad, non-complex papillary projections without large cystic spaces. (wikipedia.org)
  • From a pathology perspective, an endolymphatic sac tumor needs to be separated from metastatic renal cell carcinoma, metastatic thyroid papillary carcinoma, middle ear adenoma, paraganglioma, choroid plexus papilloma, middle ear adenocarcinoma, and ceruminous adenoma. (wikipedia.org)
  • If either tumor starts to spread into the outer layers of the bladder (lamina, muscularis, or the fatty protective tissue) the cancer is then invasive. (oncology-clinics.com)
  • Following the conference, participants should have an enhanced understanding about the diagnostic procedures and treatment planning for patients with the following types of cancer: Adenocarcinoma, Papillary Carcinoma In-Situ, Solid Papillary Tumor, Ductal Carcinoma In Situ, Invasive Lobular Carcinoma, Invasive Ductal Carcinoma. (dmu.edu)
  • History Intraductal papillary mucinous neoplasms (IPMNs) possess malignant potential and may improvement from low- to high-grade dysplasia to invasive adenocarcinoma. (crispr-reagents.com)
  • Whereas serous cystic neoplasms are benign, IPMNs as well as mucinous cystic neoplasms can progress to invasive adenocarcinoma and require surgical resection. (utoronto.ca)
  • Invasive neoplasms of the female pelvic organs account for almost 15% of all cancers in women. (medscape.com)
  • Either flat or papillary can be classified as invasive or non-invasive. (oncology-clinics.com)
  • Histologically, IPMNs are lined by flat or papillary mucinous epithelium of gastric, intestinal, pancreatobiliary, or oncocytic type, exhibiting varying degrees of dysplasia, and surrounded by dense fibrotic stroma. (utoronto.ca)
  • Adenocarcinoma of the lung is the leading cause of cancer death worldwide. (nature.com)
  • Here we report molecular profiling of 230 resected lung adenocarcinomas using messenger RNA, microRNA and DNA sequencing integrated with copy number, methylation and proteomic analyses. (nature.com)
  • These data establish a foundation for classification and further investigations of lung adenocarcinoma molecular pathogenesis. (nature.com)
  • Lung cancer is the most common cause of global cancer-related mortality, leading to over a million deaths each year and adenocarcinoma is its most common histological type. (nature.com)
  • Smoking is the major cause of lung adenocarcinoma but, as smoking rates decrease, proportionally more cases occur in never-smokers (defined as less than 100 cigarettes in a lifetime). (nature.com)
  • However, most lung adenocarcinomas either lack an identifiable driver oncogene, or harbour mutations in KRAS and are therefore still treated with conventional chemotherapy. (nature.com)
  • Our efforts focused on comprehensive, multiplatform analysis of lung adenocarcinoma, with attention towards pathobiology and clinically actionable events. (nature.com)
  • We analysed tumour and matched normal material from 230 previously untreated lung adenocarcinoma patients who provided informed consent ( Supplementary Table 1 ). (nature.com)
  • [ 3 , 4 ] The term "pseudomesotheliomatous carcinoma" was first applied by Harwood and colleagues in 1976 to 6 cases of peripheral lung adenocarcinoma that closely mimicked mesothelioma. (medscape.com)
  • found that pyroptosis-related genes can be used for prognostic prediction of skin cutaneous melanoma and lung adenocarcinoma, respectively. (nature.com)
  • International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. (qxmd.com)
  • Adenocarcinoma is the most common histologic type of lung cancer. (qxmd.com)
  • To address advances in oncology, molecular biology, pathology, radiology, and surgery of lung adenocarcinoma, an international multidisciplinary classification was sponsored by the International Association for the Study of Lung Cancer, American Thoracic Society, and European Respiratory Society. (qxmd.com)
  • This new classification strategy is based on a multidisciplinary approach to diagnosis of lung adenocarcinoma that incorporates clinical, molecular, radiologic, and surgical issues, but it is primarily based on histology. (qxmd.com)
  • Intrahepatic bile duct cancer may be relatively indolent and difficult to clinically differentiate from metastatic adenocarcinoma deposits in the liver. (tri-kobe.org)
  • Impact of intensified chemotherapy in metastatic pancreatic ductal adenocarcinoma (PDAC) in clinical routine in Europe. (cancercentrum.se)
  • We investigated whether adjuvant radiotherapy (RT) improved cancer-specific survival (CSS) and overall survival (OS) among patients undergoing surgical resection for invasive IPMN. (duke.edu)
  • All adult patients with resection of invasive IPMN from 1988 to 2007 were included. (duke.edu)
  • For resection specimens, new concepts are introduced such as adenocarcinoma in situ (AIS) and minimally invasive adenocarcinoma (MIA) for small solitary adenocarcinomas with either pure lepidic growth (AIS) or predominant lepidic growth with ≤ 5 mm invasion (MIA) to define patients who, if they undergo complete resection, will have 100% or near 100% disease-specific survival, respectively. (qxmd.com)
  • See also Pancreatic Adenocarcinoma Imaging: What You Need to Know , a Critical Images slideshow, to help identify which imaging studies to use to identify and evaluate this disease. (medscape.com)
  • She underwent EUS-FNA and was diagnosed as pancreatic adenocarcinoma. (biomedcentral.com)
  • However, there was no correlation between CEA level and cystic mucinous secretions or mucinous epithelial cytoplasm CEA staining, mucin glycoprotein expression, size of lesion, grade of dysplasia or presence of invasive carcinoma. (gastrores.org)
  • These subtypes differ in their prognosis and their risk for dysplasia and/or invasive carcinoma [ 9 - 11 ]. (gastrores.org)
  • Accordingly, mucoepidermoid carcinoma (MEC) is the most frequent subtype, with more than 30% of the SGC cases, followed by the adenoid cystic carcinoma (ACC) with the pathology in 23.8% of all SGC cases, and the adenocarcinoma not otherwise specified [ 4 ]. (genominfo.org)
  • The terms BAC and mixed subtype adenocarcinoma are no longer used. (qxmd.com)
  • In 1994, it was classified as the pathological type of cervical cancer by WHO in 1994, which is a subtype of cervical adenocarcinoma. (biomedres.info)
  • HSIL is the morphologic expression of persistent HPV infection that has the potential to progress to invasive carcinoma. (cancer.org.au)
  • As compared to the previous edition, changes include a better definition of pre-invasive lesion, a reclassification of adenocarcinoma, the description of two new tumour types as variants of large cell carcinoma, large cell neuroendocrine carcinoma (LCNEC) and basaloid carcinoma, and a new class called pleomorphic carcinoma. (ersjournals.com)
  • This new adenocarcinoma classification is needed to provide uniform terminology and diagnostic criteria, especially for bronchioloalveolar carcinoma (BAC), the overall approach to small nonresection cancer specimens, and for multidisciplinary strategic management of tissue for molecular and immunohistochemical studies. (qxmd.com)
  • A new pattern-based classification for endocervical adenocarcinomas recommends the description of patterns of invasion for human papillomavirus (HPV)-related adenocarcinomas as this is associated with differing risks of lymph node involvement. (bmj.com)
  • Recent research has also revealed clinical, radiologic, and pathologic correlates, leading to greater knowledge in molecular profiling and targeted therapeutics, as well as an emphasis on the rising incidence of adenocarcinoma histology. (scienceopen.com)
  • Comparison of diagnostic methods for the detection of a BRAF mutation in papillary thyroid cancer. (cdc.gov)
  • 4 cases of villoglandular papillary adenocarcinoma of uterine cervix admitted from 2001 to 2009 in Children's Hospital, Shanxi Provincial People's Hospital were analysed retrospectively, including detailed clinical data. (biomedres.info)
  • Villoglandular Papillary Adenocarcinoma (VGPA), also named Villoglandular Adenocarcinoma (VGA), refers to a rare welldifferentiated adenocarcinoma of uterine cervix. (biomedres.info)
  • Uterine cancer is defined as any invasive neoplasm of the uterine corpus. (medscape.com)
  • To explore the clinical and pathological features, diagnosis and therapy of Villoglandular Papillary Adenocarcinoma (VGPA). (biomedres.info)
  • With papillary, the cancer causes long tubular looking growths to form from the inner layer of the bladder wall, expanding into the center of the bladder (where urine is stored). (oncology-clinics.com)
  • The diagnosis of autoimmune pancreatitis (AIP) and immunoglobulin G4-related sclerosing cholangitis (IgG4-SC) may require a somewhat invasive pathological examination and steroid responsiveness. (bvsalud.org)
  • Papillary TCC, which represented 67.5% of all TCC, were more often of a lower grade compared to non-papillary tumours. (hku.hk)
  • Another change is the subclassification of adenocarcinoma: the definition of bronchioalveolar carcinoma has been restricted to noninvasive tumours. (ersjournals.com)
  • In 38 cases (95%), the increased risk of pancreatic cancer was based on a family history of the disease, while two patients (5%) had one immediate relative with pancreatic ductal adenocarcinoma. (scanforlife.co.za)
  • Pancreaticoduodenectomy Among Patients With Pancreatic Ductal Adenocarcinoma. (cancercentrum.se)
  • Among these, 28% were superficial while 72% were muscle-invasive and the papillary TCC usually presented at an earlier stage. (hku.hk)
  • The nuclei pile up into a cribriform/pseudo-papillary structure , imparting a complex architecture to the gland. (surgpath4u.com)