• I. To determine the rates of high-grade pancreatic neoplasia precursors (intraductal papillary mucinous neoplasm (IPMN)-high-grade dysplasia (HGD)) and pancreatic intraepithelial neoplasia-3 [PanIN-3]) and pancreatic ductal adenocarcinoma (PDAC) among all study participants. (centerwatch.com)
  • Biopsy of the liver revealed metastasis of a moderately differentiated adenocarcinoma, possibly of pancreatic origin. (aacc.org)
  • This is a Phase II, open-label, multi-center study to determine the efficacy and safety of MEDI4736 evaluated as single agent or in combination with tremelimumab in patients with metastatic pancreatic ductal adenocarcinoma (PDAC) whose disease has progressed on fluoropyrimidine containing or gemcitabine-containing first-line chemotherapy.This study will consist of Part A, lead-in, as well as a possible expansion Part B. (astrazenecaclinicaltrials.com)
  • The high incidence of incidental pancreatic adenocarcinoma especially underlines the necessity for an early surgical therapeutic approach for these patients. (iiarjournals.org)
  • Pancreatic ductal adenocarcinoma (PDAC) is the fourth most common cause of cancer related death. (biomedcentral.com)
  • Over the past decades pancreatic ductal adenocarcinoma (PDAC) has become the subject of increased research activity, however, the prognosis of this disease remains the worst amongst solid tumours. (biomedcentral.com)
  • The FOLFIRINOX regimen is the standard first-line treatment for advanced pancreatic adenocarcinoma (aPDAC). (oncotarget.com)
  • Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related death in developed countries [ 1 ], and it is expected to become the second leading cause of cancer death in 2030 [ 2 ]. (oncotarget.com)
  • Gross section of an adenocarcinoma of the pancreas measuring 5 × 6 cm resected from the pancreatic body and tail. (medscape.com)
  • See also Pancreatic Adenocarcinoma Imaging: What You Need to Know , a Critical Images slideshow, to help identify which imaging studies to use to identify and evaluate this disease. (medscape.com)
  • Pancreatic ductal adenocarcinoma (PDAC), which constitutes 90% of pancreatic cancers, is the fourth leading cause of cancer-related deaths in the world. (lu.se)
  • Pancreatic ductal adenocarcinoma (PDAC) has the lowest survival rate of all major cancers. (nih.gov)
  • pancreatic ductal adenocarcinoma. (nih.gov)
  • Further study is necessary to determine whether there is a rational relationship between mucinous cystadenoma of the pancreas and pancreatic adenocarcinoma. (elsevierpure.com)
  • Endoscopic retrograde cholangiopancreatography (ERCP) showed a cyst in the tail of the pancreas, and cytology of the pure pancreatic juice revealed adenocarcinoma. (elsevierpure.com)
  • Intraoperatively, the pancreas was cut along the portal vein, and cytology of the pancreatic juice from the pancreas distal to the cutting line showed adenocarcinoma. (elsevierpure.com)
  • ERCP showed a pancreatic cyst, and cytology of the pancreatic juice highly suggested adenocarcinoma. (elsevierpure.com)
  • To compare focal-type autoimmune pancreatitis (AIP) and pancreatic ductal adenocarcinoma (PDA) using contrast-enhanced MR imaging (CE-MRI), and to assess diagnostic performance of the lesion contrast at arterial phase (AP) (Contrast AP ) for differentiating between the two diseases. (springer.com)
  • Lee S, Kim JH, Kim SY et al (2018) Comparison of diagnostic performance between CT and MRI in differentiating non-diffuse-type autoimmune pancreatitis from pancreatic ductal adenocarcinoma. (springer.com)
  • Histological evaluation determined this was locally invasive pancreatic adenocarcinoma, and therefore the true etiology of the original cecal perforation. (biomedcentral.com)
  • Olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, is used for maintenance therapy in pancreatic adenocarcinoma. (medscape.com)
  • Olaparib has US Food and Drug Administration (FDA) approval for adults with germline BRCA -mutated metastatic pancreatic adenocarcinoma whose disease has not progressed on at least 16 weeks of a first-line platinum-based chemotherapy regimen. (medscape.com)
  • It is indicated for maintenance treatment of adults with deleterious or suspected deleterious gBRCAm metastatic pancreatic adenocarcinoma whose disease has not progressed on at least 16 weeks of a first-line platinum-based chemotherapy regimen. (medscape.com)
  • Advanced hepatocellular carcinoma, pancreatic ductal adenocarcinoma (PDAC) and biliary tract cancer. (medscape.com)
  • PanNECs can occur with admixed components of other carcinoma types of non-neuroendocrine origin, this can be either ductal adenocarcinoma (PDAC) or acinar cell carcinoma (ACC). (biomedcentral.com)
  • The two types of pancreatic carcinoma are acinar cell carcinoma and ductal adenocarcinoma . (cancer.gov)
  • Gross section of an adenocarcinoma of the pancreas measuring 5 X 6 cm resected from the pancreatic body and tail. (medscape.com)
  • Figure 3 Photomicrograph of cytologic specimen obtained by EUS-guided showing a poorly differentiated carcinoma with histological features consistent with a metastasis from his previous hepatocellular carcinoma (Papanicolaou stain, × 200). (wjgnet.com)
  • Histomorphologic appearance of the delayed pancreatic metastasis (hematoxylin and eosin × 100). (biomedcentral.com)
  • As in the lymph node metastasis, a marked desmoplastic stromal reaction is seen in the pancreatic metastasis. (biomedcentral.com)
  • Nuclear lncRNA HOXD-AS1 suppresses colorectal carcinoma growth and metastasis via inhibiting HOXD3-induced integrin β3 transcriptional activating and MAPK/AKT signalling. (biomedcentral.com)
  • B: Microscopic examination revealed metastatic hepatocellular carcinoma in the pancreas (HE, × 40). (wjgnet.com)
  • The pancreas is an uncommon but recognizable site for metastases from renal cell carcinoma (RCC). (scirp.org)
  • Chronic pancreatitis (CP) is a progressively evolving inflammation of the pancreas along with destruction of the pancreatic parenchyma and its replacement by fibrotic tissue that results in progressive loss of endocrine and exocrine functionality ( 1 ). (iiarjournals.org)
  • Negative prognostic impact of PD-L1 expression in tumor cells of undifferentiated (anaplastic) carcinoma with osteoclast-like giant cells of the pancreas: study of 13 cases comparing ductal pancreatic carcinoma and review of the literature. (nih.gov)
  • Assessment and management of undifferentiated carcinoma with osteoclastic like giant cells of the pancreas: a case report and revision of literature. (nih.gov)
  • We would like to recommend detailed examination of the pancreas including cytology of the pancreatic juice in patients with pancreatic cyst to find possible concomitant early pancreatic carcinoma. (elsevierpure.com)
  • Two cases of in situ carcinoma of the pancreas first detected with pancreatic cyst as a diagnostic clue are reported. (elsevierpure.com)
  • Case 2: A 55-yr-old Japanese man with known hepatocellular carcinoma was diagnosed as having pancreatic cyst in the tail of the pancreas on US and CT. (elsevierpure.com)
  • The diagnostic clue of in situ carcinoma of the pancreas in these two cases was a cystic lesion of the pancreas detected by check-up US and CT of known carcinoma of the stomach and liver. (elsevierpure.com)
  • In situ carcinoma of the pancreas was found to be independent of the cysts because of the different locations and divergent histopathologic natures of the two lesions. (elsevierpure.com)
  • Pancreatic cancer is a disease in which malignant (cancer) cells form in the tissues of the pancreas. (cancer.gov)
  • Tests that examine the pancreas are used to help diagnose pancreatic cancer. (cancer.gov)
  • Approximately 75% of all pancreatic carcinomas occur within the head or neck of the pancreas, 15-20% occur in the body of the pancreas, and 5-10% occur in the tail. (medscape.com)
  • PATIENTS AND METHODS: Nineteen patients with isolated unresectable liver metastases from a variety of tumors (13 uveal melanomas, 2 neuroendocrine carcinomas, 2 gastrointestinal stromal tumors, 1 hepatocellular carcinoma, and 1 high-grade sarcoma) were treated with a 60-min IHP using 200 mg melphalan. (omicsdi.org)
  • Implicated in hepatocellular carcinoma. (nih.gov)
  • Biomarker of hepatocellular carcinoma and pancreatic cancer. (nih.gov)
  • Locally advanced or metastatic hepatocellular carcinoma (HCC). (medscape.com)
  • K. Chiu, A. Razack and A. Maraveyas, "Targeted Therapy in the Management of Elderly Patients with Pancreatic Metastases from Renal Cell Carcinoma," Journal of Cancer Therapy , Vol. 4 No. 9B, 2013, pp. 15-21. (scirp.org)
  • Phase III Trial of Interferon Alfa-2a with or without 13-Cis-Retinoic Acid for Patients with Advanced Renal Cell Carcinoma," Journal of Clinical Oncology, Vol. 18, No. 16, 2000, pp. 2972-2980. (scirp.org)
  • R. I. Fisher, S. A. Rosenberg and G. Fyfe, "Long-Term Survival Update for High-Dose Recombinant Interleukin-2 in Patients with Renal Cell Carcinoma," The Cancer Journal From Scientific American, Vol. 6, Suppl. (scirp.org)
  • Randomized Phase III Trial of High-Dose Interleukin-2 versus Subcutaneous Interleukin-2 and Interferon in Patients with Metastatic Renal Cell Carcinoma," Journal of Clinical Oncology, Vol. 23, No. 1, 2005, pp. 133-141. (scirp.org)
  • Recombinant Human Interleukin-2, Recombinant Human Interferon Alfa-2a, or Both in Metastatic Renal-Cell Carcinoma," The New England Journal of Medicine, Vol. 338, No. 18, 1998, pp. 1272-1278. (scirp.org)
  • Pancreatic metastases are rare but are thought to be most commonly from renal cell carcinoma (RCC). (northwestern.edu)
  • BRCA), ataxia telangiectasia mutated gene (ATM), or PALB2 screened for pancreatic cancer. (centerwatch.com)
  • To explore knowledge, attitudes, and anxiety related to pancreatic cancer screening at annual intervals in all study participants. (centerwatch.com)
  • A disease of later life, pancreatic carcinoma is the third most common cancer of the gastrointestinal tract and the sixth most common cause of cancer deaths. (gpnotebook.com)
  • In addition, CP is considered a risk factor for pancreatic cancer, whereas the overall incidence of cancer occurrence remains unspecified ( 7 , 8 ). (iiarjournals.org)
  • Recommendations for screening of patients with CP for pancreatic cancer do not exist and, due to a wide diversity of clinical and morphological presentations of CP, the differentiation between CP and pancreatic cancer, especially in cases when malignant tumor growth appears in the course of CP, is challenging ( 4 ). (iiarjournals.org)
  • We developed a high-throughput 3D cell culture drug screening system for pancreatic cancer, which displays a strongly increased chemoresistance. (biomedcentral.com)
  • The third objective was to study the biological and clinical implications of S100A10 in pancreatic cancer. (dal.ca)
  • S100A10 mRNA levels were also predictive of overall and recurrence-free survival in pancreatic cancer patients. (dal.ca)
  • Both the incidence and the death rates for pancreatic cancer are increasing. (medscape.com)
  • The initial manifestations of pancreatic cancer are often nonspecific, and consequently are often misinterpreted. (medscape.com)
  • Pancreatic cancer is notoriously difficult to diagnose in its early stages. (medscape.com)
  • Laboratory findings in patients with pancreatic cancer are usually nonspecific. (medscape.com)
  • Occasionally, the presence of pancreatic cancer is suggested by elevated liver transaminase, bilirubin, and alkaline phosphatase levels on testing performed for other purposes. (medscape.com)
  • Patients with advanced pancreatic cancer and weight loss have laboratory evidence of malnutrition (eg, low serum albumin or cholesterol level). (medscape.com)
  • Surgery is the only potentially curative treatment modality for early-stage pancreatic cancer. (medscape.com)
  • The objective of this study was to evaluate the safety of escalating up to 55 Gy within five weeks, the dose of external beam radiotherapy to the previous tumor site concurrently with a fixed daily dose of capecitabine, in patients with resected pancreatic cancer. (unibo.it)
  • The Italian Rare Pancreatic Exocrine Cancer Initiative. (nih.gov)
  • Expression of L1CAM, COX-2, EGFR, c-KIT and Her2/neu in anaplastic pancreatic cancer: putative therapeutic targets? (nih.gov)
  • Endoscopic ultrasonography guided tissue acquisition (EUS + TA) is used to provide a tissue diagnosis in patients with suspected pancreatic cancer . (bvsalud.org)
  • EUS-FNA was performed to the pancreatic head and pancreatic body tumors, and the same high atypical type cells suspected of cancer were obtained from either specimen, and finally total pancreatectomy was performed. (elsevierpure.com)
  • Case 1: Ultrasonography (US) and computed tomography (CT) in a 54-yr-old Japanese man with a known gastric cancer revealed a pancreatic cyst. (elsevierpure.com)
  • Chari ST, Takahashi N, Levy MJ et al (2009) A diagnostic strategy to distinguish autoimmune pancreatitis from pancreatic cancer. (springer.com)
  • Kamisawa T, Imai M, Yui Chen P et al (2008) Strategy for differentiating autoimmune pancreatitis from pancreatic cancer. (springer.com)
  • Kim JH, Kim MH, Byun JH et al (2012) Diagnostic strategy for differentiating autoimmune pancreatitis from pancreatic cancer: is an endoscopic retrograde pancreatography essential. (springer.com)
  • Pancreatic cancer is often locally and distally aggressive, but initial presentation as cecal perforation is uncommon. (biomedcentral.com)
  • However, pancreatic cancer initially presenting with cecal perforation secondary to large bowel obstruction from local colon invasion is distinctly uncommon. (biomedcentral.com)
  • Hypoxia potentiates gemcitabine-induced stemness in pancreatic cancer cells through AKT/Notch1 signaling. (biomedcentral.com)
  • The most active agents for pancreatic cancer have been 5-fluorouracil (5-FU) and gemcitabine. (medscape.com)
  • Response rates are typically less than 20% in pancreatic cancer. (medscape.com)
  • Erlotinib has been approved by the FDA for use, in combination with gemcitabine, as a first-line treatment for locally advanced, unresectable, or metastatic pancreatic cancer. (medscape.com)
  • Modifying the following risk factors may help reduce your risk of pancreatic cancer. (empowher.com)
  • You are risking pancreatic cancer, as well as other serious diseases. (empowher.com)
  • Alcohol consumption may lead to pancreatic cancer. (empowher.com)
  • not only increases your risk of pancreatic cancer but may also reduce your chance of survival if you are ever diagnosed with this condition. (empowher.com)
  • You have a higher-than-normal risk of developing pancreatic cancer if you work in the petroleum and dry-cleaning industries, or if your job entails the use of pesticides and dyes. (empowher.com)
  • One study suggests a link between high folate intake and decreased risk of pancreatic cancer. (empowher.com)
  • Detailed guide: pancreatic cancer. (empowher.com)
  • Pancreatic cancer: diagnosis and management. (empowher.com)
  • Screening for pancreatic cancer. (empowher.com)
  • Body mass index and risk, age of onset, and survival in patients with pancreatic cancer. (empowher.com)
  • There are four types of pancreatic cancer in children. (cancer.gov)
  • Signs and symptoms of pancreatic cancer include feeling tired and weight loss. (cancer.gov)
  • This makes it hard to diagnose pancreatic cancer early. (cancer.gov)
  • There is consensus on the fact that surgery is the primary mode of treatment for pancreatic cancer. (medscape.com)
  • [ 56 ] This has led to US Food and Drug Administration (FDA) approval of erlotinib to be used in combination with gemcitabine in advanced, unresectable pancreatic cancer. (medscape.com)
  • The combination of gemcitabine and capecitabine in advanced pancreatic cancer has been investigated by several groups. (medscape.com)
  • Accordingly, these researchers recommended considering gemcitabine-capecitabine as one of the standard first-line options in locally advanced and metastatic pancreatic cancer. (medscape.com)
  • Pancreatic cancer is the fourth leading cause of cancer deaths, being responsible for 7% of all cancer-related deaths in both men and women. (medscape.com)
  • The initial symptoms of pancreatic cancer are often quite nonspecific and subtle in onset. (medscape.com)
  • Surgery is the primary mode of treatment for pancreatic cancer. (medscape.com)
  • Acinar cell carcinoma is a rare cause of pancreatic cancer. (msdmanuals.com)
  • Genetic testing is now offered routinely to all patients diagnosed with pancreatic cancer. (msdmanuals.com)
  • Symptoms of pancreatic cancer such as pain and weight loss are nonspecific, leading to a later diagnosis by which time the disease has spread. (msdmanuals.com)
  • Pancreatic cancer causes diabetes in up to half of patients, leading to symptoms of glucose intolerance (eg, polyuria and polydipsia). (msdmanuals.com)
  • Pancreatic neuroendocrine tumors display a range of clinical presentations and outcomes. (unina.it)
  • Pancreatic neuroendocrine tumors (PNETs): incidence, prognosis and recent trend toward improved survival. (unina.it)
  • Daily oral everolimus activity in patients with metastatic pancreatic neuroendocrine tumors after failure of cytotoxic chemotherapy: a phase II trial. (unina.it)
  • Updated safety and efficacy results of the phase III trial of sunitinib (SU) versus placebo (PBO) for treatment of pancreatic neuroendocrine tumors (NET). (unina.it)
  • His image findings showed pancreatic head cysts and pancreatic head, body, and tail tumors respectively. (elsevierpure.com)
  • histology showed that the same anaplastic pancreatic ductal carcinoma (spindle cell type) was obtained from the pancreatic head cyst and the pancreatic tumors. (elsevierpure.com)
  • Prognosis after surgery for multiple endocrine neoplasia type 1-related pancreatic neuroendocrine tumors: Functionality matters. (omicsdi.org)
  • Metastasized pancreatic neuroendocrine tumors are the leading cause of death in patients with multiple endocrine neoplasia type 1. (omicsdi.org)
  • Aside from tumor size, prognostic factors of pancreatic neuroendocrine tumors are largely unknown. (omicsdi.org)
  • The present study aimed to assess whether the prognosis of patients with resected multiple endocrine neoplasia type 1-related nonfunctioning pancreatic neuroendocrine tumors differs from those with resected multiple endocrine neoplasia type 1-related insulinomas and assessed factors associated with prognosis. (omicsdi.org)
  • Patients who underwent resection of a multiple endocrine neoplasia type 1-related pancreatic neuroendocrine tumors between 1990 and 2016 were identified in 2 databases: the DutchMEN Study Group and the International MEN1 Insulinoma Study Group databases. (omicsdi.org)
  • Cox regression was performed to compare liver metastases-free survival of patients with a nonfunctioning pancreatic neuroendocrine tumors versus those with an insulinoma and to identify factors associated with liver metastases-free survival. (omicsdi.org)
  • Pancreatic neuroendocrine neoplasms (PanNENs) fall into two subclasses: the well-differentiated, low- to high-grade pancreatic neuroendocrine tumors (PanNETs), and the poorly-differentiated, high-grade pancreatic neuroendocrine carcinomas (PanNECs). (biomedcentral.com)
  • With this approach, PanNENs fall into two basic subtypes: well-differentiated pancreatic neuroendocrine tumors (PanNETs) and poorly differentiated pancreatic neuroendocrine carcinomas (PanNECs) [ 4 ]. (biomedcentral.com)
  • These tumors are also called pancreatic neuroendocrine tumors (pancreatic NETs). (cancer.gov)
  • In children, some pancreatic tumors do not secrete hormones and there are no signs and symptoms of disease. (cancer.gov)
  • Pancreatic tumors that do secrete hormones may cause signs and symptoms. (cancer.gov)
  • Pancreatic neuroendocrine tumors may be functional or nonfunctional. (medscape.com)
  • Pancreatic islet cell tumors may secrete 2 or more polypeptide hormones. (medscape.com)
  • Mesothelin (MSLN) is overexpressed in many human tumors, including mesotheliomas and pancreatic and ovarian carcinomas. (cdc.gov)
  • Most pancreatic cancers are exocrine tumors that develop from ductal and acinar cells. (msdmanuals.com)
  • Pancreatic neuroendocrine neoplasms (PanNENs) have undergone several classification changes according to consensus guidelines [ 1 ]. (biomedcentral.com)
  • This is a case of a 75-year-old man who was diagnosed with anaplastic pancreatic ductal carcinoma (spindle cell type). (elsevierpure.com)
  • Conclusion: DC-based immunotherapy may not only be successfully combined with gemcitabine for the treatment of advanced pancreatic carcinoma, but may also be effective in preventing local recurrence or metastatization in tumor-free patients. (uni-muenchen.de)
  • The results of our study indicate that a total radiation dose up to 55.0 Gy/5 weeks can be safely administered to the tumor bed, concurrently with capecitabine (1600 mg/m (2)) in patients with resected pancreatic carcinoma. (unibo.it)
  • Advanced pheochromocytoma/paraganglioma (PPGL) or pancreatic neuroendocrine tumor (pNET). (medscape.com)
  • This is the most common type of pancreatic tumor in children. (cancer.gov)
  • Moertel CG, Kvols LK, O'Connell MJ, Rubin J. Treatment of neuroendocrine carcinomas with combined etoposide and cisplatin. (unina.it)
  • Isolated pancreatic RCC metastases are still rarer and often present years after initial nephrectomy. (scirp.org)
  • We report our experience of 6 patients with pancreatic RCC metastases. (scirp.org)
  • median age 78 years) were diagnosed to have pancreatic RCC metastases at our institute. (scirp.org)
  • The median interval between initial curative nephrectomy and re-presentation with pancreatic metastases w as 12.5 years. (scirp.org)
  • Pancreatic metastases from RCC are typically T1 hypointense and T2 hyperintense. (northwestern.edu)
  • Results Of the 182 patients, 33 (18%) had pancreatic, 94 (52%) pulmonary, 30 (16%) bone, 13 (7%) hepatic, and 12 (7%) brain metastases. (unisr.it)
  • Adenoviral p53 gene transfer and gemcitabine in three patients with liver metastases due to advanced pancreatic carcinoma. (omicsdi.org)
  • METHODS: In a non-randomized pilot trail we tested whether a local therapy based upon an adenoviral gene transfer of wild type p53 in combination with gemcitabine administration would be safe in patients with liver metastases due to pancreatic carcinoma. (omicsdi.org)
  • The aim of this study was the bi-national analysis of patients who underwent pancreatic resection for suspected chronic pancreatitis at an Austrian and a German high-volume center with regard to overall postoperative outcome and incidental carcinoma sequence. (iiarjournals.org)
  • The management of these patients is comprised of either surgical resection or a follow-up with imaging studies, depending on the risk factors of malignancy, representing with a mass or nodule, MPD dilation ≥ 10 mm and obstructive jaundice in BD-IPMN localised in a pancreatic head. (amedi.sk)
  • Diagnostic accuracy of endoscopic ultrasonography-guided tissue acquisition prior to resection of pancreatic carcinoma: a nationwide analysis. (bvsalud.org)
  • assess practice variation regarding KPI of EUS + TA prior to resection of pancreatic carcinoma in the Netherlands . (bvsalud.org)
  • Results of all EUS + TA prior to resection of pancreatic carcinoma from 2014-2018, were extracted from the national Dutch Pathology Registry (PALGA). (bvsalud.org)
  • Dendritic cell-based vaccination combined with gemcitabine increases survival in a murine pancreatic carcinoma model. (uni-muenchen.de)
  • We have previously shown that gemcitabine sensitizes human pancreatic carcinoma cells against CTL-mediated lysis. (uni-muenchen.de)
  • Here, we used a murine pancreatic carcinoma model to investigate whether combination with gemcitabine increases therapeutic efficacy of DCbased vaccination. (uni-muenchen.de)
  • Figure 2 A 52-year-old man with moderately-differentiated pancreatic head carcinoma. (wjgnet.com)
  • Pancreatic head carcinoma with a vascularized inhomogeneous mass and a dilatation of the common bile duct and pancreatic duct. (ultrasoundcases.info)
  • 10% of pancreatic cancers are associated with an underlying genetic component. (msdmanuals.com)
  • Together, these findings delineated a fundamental role of plasminogen activation, particularly that of S100A10 in lung and pancreatic carcinomas. (dal.ca)
  • Histopathologic diagnosis of pancreatic cyst was mucinous cystadenoma. (elsevierpure.com)
  • Manfredi R, Frulloni L, Mantovani W, Bonatti M, Graziani R, Mucelli RP (2011) Autoimmune pancreatitis: pancreatic and extrapancreatic MR imaging-MR cholangiopancreatography findings at diagnosis, after steroid therapy, and at recurrence. (springer.com)
  • Glucose measurements are used in the diagnosis and treatment of pancreatic islet cell carcinoma and of carbohydrate metabolism disorders, including diabetes mellitus, neonatal hypoglycemia, and idiopathic hypoglycemia. (cdc.gov)
  • A total of 175 resections of the pancreatic head (69.4%), 37 distal pancreatectomies (14.7%), 23 total pancreatectomies (9.1%) and 18 other pancreatic resections (7.1%) were performed within our study period. (iiarjournals.org)
  • While SOX9 is absent in committed endocrine precursors, it is an important player in pancreatic ductal and centro-acinar cell development but not in adult acinar cells [ 36 , 37 ]. (biomedcentral.com)
  • Possible complications include dilatation, distortion and stricture of the pancreatic ducts, calcification of the pancreatic parenchyma, formation of pseudocysts, duodenal or common bile duct stenosis, or the formation of superior mesenteric, portal or splenic vein thrombosis which may each severely affect the patient's quality of life and overall prognosis ( 1 , 6 ). (iiarjournals.org)
  • IPMN is a mucin-producing papillary neoplasia of the pancreatic ducts, showing a variable degree of atypia and causing a dilation of the pancreatic ducts. (amedi.sk)
  • Histopathologically, the cyst was mucinous cystadenoma, and the surrounding pancreatic ducts and ductules showed epithelial dysplasia of moderate-to- severe degree having foci of unequivocal in situ carcinoma. (elsevierpure.com)
  • CD34-positive cells were counted as microvessels (tan color), moderate MVDs in hot spot area of the neoplastic cells in moderately-differentiated pancreatic carcinoma. (wjgnet.com)
  • Methods: Bone marrow-derived DC from C57BL/6 mice were loaded with UV-irradiated, syngeneic Panc02 carcinoma cells and were administered subcutaneously. (uni-muenchen.de)
  • Patients and Methods: Overall, 252 consecutive pancreatic resections for suspected chronic pancreatitis were performed at the two institutions between 2005 and 2015. (iiarjournals.org)
  • MATERIAL AND METHODS: Patients with resected pancreatic carcinoma were eligible for this study. (unibo.it)
  • Moertel CG, Lefkopoulo M, Lipsitz S, Hah RG, Klaassen D. Streptozocin-doxorubicin, streptozocin-fluorouracil or chlorozotocin in the treatment of advanced islet-cell carcinoma. (unina.it)
  • Pancreatic islet cells are part of the diffuse neuroendocrine system of the gut and pancreatic endocrine system. (medscape.com)
  • It occurs more often in middle-aged women in a pancreatic body or tail. (amedi.sk)
  • Capecitabine based postoperative accelerated chemoradiation of pancreatic carcinoma. (unibo.it)
  • Conclusion: The results of our study demonstrate that pancreatic resections for chronic pancreatitis may nowadays be considered technically feasible and safe. (iiarjournals.org)
  • A: Pancreatic-phase helical CT enhancement imaging 35 s after administration of contrast agent revealed that CT enhancement of mass in pancreatic head was slightly lower than that of normal pancreatic tissues. (wjgnet.com)
  • Pancreatic cystic lesions are represented with non-neoplastic cysts, pancreatic cystic neoplasia and pseudocysts. (amedi.sk)
  • Cochrane Abstracts , Evidence Central , evidence.unboundmedicine.com/evidence/view/Cochrane/434416/all/Palliative_biliary_stents_for_obstructing_pancreatic_carcinoma. (unboundmedicine.com)