Internuclear ophthalmoplegiaPtosisParalysisBell'sAtaxiaVertical gaze palsySupranuclear palsySyndromeThird nerveNystagmusLinked with supranuclearAcuteLesionsSymptomsConjugate gazePupillaryDiplopiaLesionPseudobulbarDisordersMedialGaze palsiesCranial nervesProgressive ScoliosisSaccadesSeverePupilsHorizontalDeficitInabilityOccurOnset
Internuclear ophthalmoplegia7
- Andrew Lee, MD, describes how to differentiate internuclear ophthalmoplegia from third nerve palsy. (neurodiem.nl)
- Of the 27 patients whose ophthalmoplegia was examined monthly, few had findings suggestive of supranuclear involvement: preservation of Bell's phenomenon despite paralysis of voluntary upward gaze in two, gaze-evoked horizontal dissociated nystagmus in two, preservation of convergence despite adduction palsy with conjugate gaze in one, and internuclear ophthalmoplegia in one. (neurology.org)
- Internuclear ophthalmoplegia results from damage to the medial longitudinal fasciculus, interrupting fibres projecting from the abducens nucleus in the pons to the contralateral medial rectus subnucleus of the III nerve nucleus in the midbrain, which mediates adduction during conjugate lateral gaze. (neuroophthalmology.ca)
- Bilateral internuclear ophthalmoplegia is not uncommon. (neuroophthalmology.ca)
- Ischemia and demyelination are the most common causes of internuclear ophthalmoplegia. (neuroophthalmology.ca)
- Fisher CM. Neuroanatomic evidence to explain why bilateral internuclear ophthalmoplegia may result from occlusion of a unilateral pontine branch artery. (neuroophthalmology.ca)
- Internuclear ophthalmoplegia - Lesion in medial longitudinal fasciculus, cannot adduct in horizontal lateral gaze, but normal convergence. (wikem.org)
Ptosis10
- Increasing left ptosis developing upon sustained upward gaze in a patient with myasthenia gravis (A through F). Note the limited elevation of the left eye denoting superior rectus palsy (A). A initially, C after around 20 seconds, F after 1 minute. (medscape.com)
- During hospital day 1, the patient experienced hypophonia, complete ophthalmoplegia, bilateral ptosis (right more than left), pupils unresponsive to light, dysphagia, and bilateral limb-girdle muscular weakness. (cdc.gov)
- Stalpers reported an instance of an individual using the Miller Fisher variant of GBS who got isolated bilateral ptosis as the just ophthalmologic indication (without ophthalmoplegia), but their individual got ataxia and positive anti-GQ1b IgG antibodies [12]. (iros2005.org)
- He reports that at age five he experienced three weeks duration of ophthalmoplegia in the right eye with ptosis, dilated pupil, and accompanying severe headache. (eyerounds.org)
- At the time of the recent ophthalmoplegia, headache and ptosis, he underwent cerebral angiography at an outside facility to rule out aneurysm, which was normal. (eyerounds.org)
- Based on his examination findings of mild residual right 3rd nerve palsy with mild pupil involvement, slight ptosis of the right eye and the MRI which showed an enlarged enhancing right third nerve at its exit from the brainstem, the differential included ophthalmoplegic migraine, schwannoma or granulomatous disease. (eyerounds.org)
- We believe that the 'ptosis' documented by ED physicians was in fact a combination of hypersomnia with vertical gaze palsy . (symptoma.com)
- No patients had ophthalmoplegia or ptosis. (unicamp.br)
- Ptosis and diplopia from ophthalmoplegia with an ipsilateral mydriatic pupil may suggest a third nerve palsy versus an ipsilateral miotic pupil and mild ptosis which may suggest a concomitant Horner syndrome. (eyewiki.org)
- The affected individuals present at birth with ptosis, ophthalmoplegia, exotropia, facial weakness, facial dysmorphisms, and, in most cases, distal congenital joint contractures, and subsequently develop intellectual disabilities, gait disorders with proximal joint contractures, Kallmann syndrome (hypogonadotropic hypogonadism and anosmia), and a progressive peripheral neuropathy during the first decade of life. (scilifelab.se)
Paralysis4
- Palsy refers to paralysis, which can range from partial to complete. (merckmanuals.com)
- During the ensuing 4 days, a rapidly ascending polyradiculoneuropathy resulted in tetraparesis, followed by facial palsy, ophthalmoplegia, and then paralysis of all cranial nerves. (cdc.gov)
- The clinical signs of botulism typically consist of bilateral, symmetric cranial nerve palsies and descending, symmetric, flaccid paralysis ( 2 , 3 ). (cdc.gov)
- Ophthalmoplegia is a paralysis or weakness of one or more of the muscles that control eye movement. (nih.gov)
Bell's3
- Ramsay Hunt syndrome is sometimes compared to Bell's palsy . (allaboutvision.com)
- However, Ramsay Hunt syndrome has a known cause (varicella-zoster virus), whereas Bell's palsy does not have an exact origin. (allaboutvision.com)
- Experts suggest that symptoms and recovery are worse with Ramsay Hunt syndrome than they are with Bell's palsy. (allaboutvision.com)
Ataxia9
- An acute neurological disorder characterized by the triad of ophthalmoplegia, ataxia, and disturbances of mental activity or consciousness. (curehunter.com)
- Besides the characteristic clinical triad (ophthalmoplegia, ataxia, and areflexia), pupillary abnormalities, blepharoptosis, and facial palsy are frequent in MFS, whereas sensory loss is unusual despite the presence of profound ataxia. (neurology.org)
- Miller Fisher syndrome (MFS) is characterized by the clinical triad of ophthalmoplegia, ataxia, and areflexia, and is considered a variant form of Guillain-Barré syndrome (GBS). (neurology.org)
- All 53 patients with MFS with the clinical triad of MFS (ophthalmoplegia, ataxia, and areflexia) and acute onset without major limb weakness or other signs suggestive of CNS involvement were selected. (neurology.org)
- We also assessed the period to the beginning of recovery and for the disappearance of ophthalmoplegia and ataxia from time of onset. (neurology.org)
- The neurologic symptoms are given in the table , at which time there was complete external ophthalmoplegia in 15 patients (30%), and 15 patients (30%) could not walk independently owing to ataxia. (neurology.org)
- He by no means developed ophthalmoplegia or ataxia. (iros2005.org)
- It is seen as a ophthalmoplegia, areflexia, and ataxia [2]. (iros2005.org)
- Our individual under no circumstances developed either ataxia or ophthalmoplegia during his illness. (iros2005.org)
Vertical gaze palsy5
- Parinaud syndrome (dorsal midbrain syndrome), a conjugate upward vertical gaze palsy, may result from a pineal tumor that compresses the midbrain or, less commonly, a tumor or infarct of the midbrain pretectum. (msdmanuals.com)
- Mesencephalic damage is typically characterised by vertical gaze palsy and ophthalmoplegia. (symptoma.com)
- Interestingly, six patients from the selected group showed disorders of the ocular motor control and two patients a vertical gaze palsy . (symptoma.com)
- It is characterized by vertical gaze palsy and ophthalmoplegia. (symptoma.com)
- Niemann-Pick type C is an uncommon neurodegenerative lysosomal storage disorder that can cause a progressive neuropsychiatric syndrome associated with supranuclear vertical gaze palsy and a movement disorder. (bmj.com)
Supranuclear palsy15
- These lesions can be caused by stroke, or conditions such as Koerber-Salus-Elschnig syndrome, Progressive supranuclear palsy, Olivopontocerebellar syndrome, Niemann-Pick Disease, Type C, or envenomation such as from a scorpion sting. (wikipedia.org)
- People who have this problem often have progressive supranuclear palsy (PSP). (medlineplus.gov)
- Ling H. Clinical approach to progressive supranuclear palsy. (medlineplus.gov)
- Progressive supranuclear palsy (PSP) is a neurodegenerative disease (see the image below) whose characteristics include supranuclear, initially vertical, gaze dysfunction accompanied by extrapyramidal symptoms and cognitive dysfunction. (medscape.com)
- Sagittal T1-weighted image shows atrophy of midbrain, preservation of pontine volume, and atrophy of the tectum, suggestive of progressive supranuclear palsy (Steele-Olszewski-Richardson disease). (medscape.com)
- Progressive Supranuclear Palsy (PSP) Progressive supranuclear palsy is a rare, degenerative central nervous system disorder that progressively impairs voluntary eye movements and causes bradykinesia, muscular rigidity with progressive. (msdmanuals.com)
- Supranuclear Palsy, Progressive" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)
- This graph shows the total number of publications written about "Supranuclear Palsy, Progressive" by people in this website by year, and whether "Supranuclear Palsy, Progressive" was a major or minor topic of these publications. (uchicago.edu)
- Below are the most recent publications written about "Supranuclear Palsy, Progressive" by people in Profiles. (uchicago.edu)
- Using Downgaze Palsy Progression Rate to Model Survival in Progressive Supranuclear Palsy-Richardson Syndrome. (uchicago.edu)
- A Modified Progressive Supranuclear Palsy Rating Scale for Virtual Assessments. (uchicago.edu)
- Disease course and treatment patterns in progressive supranuclear palsy: A real-world study. (uchicago.edu)
- Safety of the tau-directed monoclonal antibody BIIB092 in progressive supranuclear palsy: a randomised, placebo-controlled, multiple ascending dose phase 1b trial. (uchicago.edu)
- An atypical variant of progressive supranuclear palsy (PSP), a rare late-onset neurodegenerative disease, by prominent early parkinsonism (tremor, limb bradykinesia, axial and limb rigidity) rather than falls and cognitive change. (nih.gov)
- Follow this link to review classifications for Progressive supranuclear palsy-parkinsonism syndrome in Orphanet. (nih.gov)
Syndrome2
- The varieties most commonly encountered by an ophthalmologist are 3rd cranial nerve palsy and Horner syndrome. (nih.gov)
- These patients describe an oropharyngeal variant of Guillain-Barré syndrome in terms of anti-GQ1b antibody reactivity and show that high titre anti-GQ1b antibodies, serologically indistinguishable from those found in Miller Fisher syndrome, can occur in a clinical setting without ophthalmoplegia. (unicamp.br)
Third nerve4
- Pupil-involving third nerve palsy is considered a neurological as it is most often due to a posterior communicating artery aneurysm compressing the nerve. (nih.gov)
- Pupil-sparing third nerve palsy is most often due to an ischemic vascular cause and usually resolves spontaneously in 3 months. (nih.gov)
- Given the present and past association of a third nerve palsy with severe migraine in a child and as a young adult, followed by resolution within weeks, it was felt that the patient most likely had ophthalmoplegic migraines. (eyerounds.org)
- A pupil involving third nerve palsy may occur with subarachnoid hemorrhage from ruptured posterior communicating artery aneurysm. (eyewiki.org)
Nystagmus6
- However, sometimes a patient exhibits an abduction nystagmus in both eyes, indicating evidence of a conjugate gaze palsy. (wikipedia.org)
- Milder palsies may cause only nystagmus or inability to maintain fixation. (msdmanuals.com)
- In upward vertical gaze palsies, the pupils may be dilated, and vertical nystagmus occurs during upward gaze. (msdmanuals.com)
- Eye movement abnormalities include nystagmus, external rectus palsies, and reduced conjugate gaze. (curehunter.com)
- A neurologist had documented gaze-evoked nystagmus and a left VI nerve palsy. (neuroophthalmology.ca)
- Dissociated nystagmus of this sort is not specific for INO, as it can be seen with other ocular motor palsies, particularly when the unaffected eye has impaired vision for other reasons. (neuroophthalmology.ca)
Linked with supranuclear1
- Tests will be done to check for diseases linked with supranuclear ophthalmoplegia. (medlineplus.gov)
Acute4
- Acute oropharyngeal palsy is associated with antibodies to GQ1b and GT1a gangliosides. (unicamp.br)
- Three patients with acute oropharyngeal palsy had high titre anti-GQ1b and anti-GT1a IgG antibodies. (unicamp.br)
- The anti-GQ1b and anti-GT1a antibody assays may be helpful tests when considering the differential diagnosis of acute oropharyngeal palsy. (unicamp.br)
- A patient presented with acute ophthalmoplegia secondary to mass effect from an intracavernous ICA fusiform aneurysm. (surgicalneurologyint.com)
Lesions3
- Nonselective horizontal gaze palsies are caused by lesions in the Abducens nucleus. (wikipedia.org)
- Vertical gaze palsies commonly result from midbrain lesions, usually infarcts and tumors. (msdmanuals.com)
- Lesions of the superior orbital fissure, orbital apex, or cavernous sinus, present in combination with other cranial nerve palsies. (nih.gov)
Symptoms4
- Symptoms of conjugate gaze palsies include the impairment of gaze in various directions and different types of movement, depending on the type of gaze palsy. (wikipedia.org)
- Treatment depends on the cause and symptoms of the supranuclear ophthalmoplegia. (medlineplus.gov)
- Peripheral-type facial palsy was found in 16 (32%) patients, in 6 (38%) of whom it had worsened when the other neurologic symptoms were lessening. (neurology.org)
- Damage to the oculomotor nerve , termed oculomotor nerve palsy is known by the down n' out symptoms. (wikidoc.org)
Conjugate gaze2
- A patient may be diagnosed with a conjugate gaze palsy by a physician performing a number of tests to examine the patient's eye movement abilities. (wikipedia.org)
- A conjugate gaze palsy is inability to move both eyes together in a single horizontal (most commonly) or vertical direction. (msdmanuals.com)
Pupillary1
- Botulism can be another neuromuscular junction disorder that should be considered, and inside our individual, it had been excluded in the current presence of regular pupillary function and in the lack of ophthalmoplegia. (iros2005.org)
Diplopia3
- Zeiger, Roni F.. "Diplopia or Ophthalmoplegia. (unboundmedicine.com)
- Medicine Central , im.unboundmedicine.com/medicine/view/Diagnosaurus/114386/all/Diplopia_or_ophthalmoplegia. (unboundmedicine.com)
- Diplopia worse with distance is more typical of sixth nerve palsy because of difficulty with divergence at distance of the eyes while diplopia worse at near is more suggestive of medial rectus palsy because of the need for convergence of the eyes at near. (eyewiki.org)
Lesion2
- Almost all conjugate gaze palsies originate from a lesion somewhere in the brain stem, usually the midbrain, or pons. (wikipedia.org)
- The location of the lesion determines the type of palsy. (wikipedia.org)
Pseudobulbar1
- Subsequently, two of the patients showed signs of pseudobulbar palsy with abnormalities in the pons on MRI scanning, suggesting central pontine myelinolysis (CPM). (symptoma.com)
Disorders2
- Conjugate gaze palsies are neurological disorders affecting the ability to move both eyes in the same direction. (wikipedia.org)
- Some serious disorders causing the palsy may worsen, resulting in a serious, life-threatening condition. (merckmanuals.com)
Medial1
- As seen in horizontal saccadic palsy, the impairment of the contralateral side gaze is caused by the disrupted pathways coming from the PPRF, while the "half" impairment is from the signal passing through the medial longitudinal fascicles not being able to reach its target. (wikipedia.org)
Gaze palsies2
- Horizontal gaze palsies are known to be linked to Progressive Scoliosis. (wikipedia.org)
- Conjugate gaze palsies can be classified into palsies affecting horizontal gaze and vertical gaze. (wikipedia.org)
Cranial nerves1
- The soft tissue is extending anteriorly in right parasellar region, obliterating right side cavernous sinus with possible involvement of right side cranial nerves traversing the cavernous sinus which explains right side ophthalmoplegia. (neuroradiologycases.com)
Progressive Scoliosis4
- Horizontal gaze palsy with progressive scoliosis (HGPPS) is a disorder that affects vision and also causes an abnormal curvature of the spine ( scoliosis ). (medlineplus.gov)
- Five new consanguineous families with horizontal gaze palsy and progressive scoliosis and novel ROBO3 mutations. (medlineplus.gov)
- Neurologic features of horizontal gaze palsy and progressive scoliosis with mutations in ROBO3. (medlineplus.gov)
- Horizontal gaze palsy with progressive scoliosis can result from compound heterozygous mutations in ROBO3. (medlineplus.gov)
Saccades1
- This damage normally happens in the oculomotor nucleus of the midbrain As in horizontal saccadic palsy, the saccades are stopped or slowed from the disrupted pathway, only in this case the signal is disrupted before it reaches the PPRF. (wikipedia.org)
Severe1
- Admission to the intensive care unit (ICU) should be considered for all patients with labile dysautonomia, a forced vital capacity of less than 20 mL/kg, or severe bulbar palsy. (medscape.com)
Pupils1
- A palsy of the 3rd cranial nerve can impair eye movements, the response of pupils to light, or both. (merckmanuals.com)
Horizontal4
- These palsies can affect gaze in a horizontal, upward, or downward direction. (wikipedia.org)
- For example, a person with a horizontal saccadic palsy may jerk their head around while watching a movie or high action event instead of keeping their head steady and moving their eyes, which usually goes unnoticed. (wikipedia.org)
- Someone with a nonselective horizontal gaze palsy may slowly rotate their head back and forth while reading a book instead of slowly scanning their eyes across the page. (wikipedia.org)
- One other type of gaze palsy is a horizontal saccadic palsy. (wikipedia.org)
Deficit1
- The primary outcome variables evaluated via a binary random-effects model were improvements in endocrine deficit, visual field deficit, visual acuity deficit, and ophthalmoplegia or ocular nerve palsy (O/ONP). (cns.org)
Inability1
- In most cases, the gaze palsy can simply be seen by inability to move both eyes in one direction. (wikipedia.org)
Occur1
- These palsies can occur when pressure is put on the nerve or the nerve does not get enough blood. (merckmanuals.com)
Onset1
- Childhood-onset of recurrent headaches with an oculomotor cranial nerve palsy. (nih.gov)