Loading...
  • novo
  • The breakdown of proteins generates free amino acids that serve two functions: they are utilized for the de novo synthesis of proteins to support basic cellular functions and as substrates for the Krebs cycle to ensure cellular energy support ( 1 ). (mcponline.org)
  • quantitative
  • We studied global protein dynamics during amino acid starvation-induced autophagy by quantitative mass spectrometry and were able to record nearly 1500 protein profiles during 36 h of starvation. (mcponline.org)
  • Quantitative analysis of a phosphoproteome readily altered by the protein kinase CK2 inhibitor quinalizarin in HEK-293T cells. (lu.se)
  • Genes
  • Genes involved in nutrient partitioning, specifically grain filling, will be used to identify other co-regulated genes, and DNA binding proteins. (biomedcentral.com)
  • substrate
  • To study substrate selectivity of autophagy, we measured the relative abundance of proteins in the cell during amino acid starvation on a proteome scale. (mcponline.org)
  • pathways
  • Two of the major effects of starvation are a decreased protein synthesis and the activation of proteolytic pathways. (mcponline.org)
  • biochemistry
  • Protein Lipidation Protocols offers biochemists, cell and molecular biologists, medicinal chemists, and pharmaceutical researchers state-of-the-art tools for understanding the complex biochemistry of protein lipidation, as well as catalyzing the development of many important new biopharmaceuticals, including anticancer drugs. (springer.com)
  • cellular
  • Numerous proteins undergo modification by palmitic acid (S-acylation) for their biological functions including signal transduction, vesicular transport and maintenance of cellular architecture. (oup.com)
  • versus
  • Label-free protein quantification in freshly ejaculated versus post-mating spermatophores of the noble crayfish Astacus astacus. (lu.se)
  • antibody
  • If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production , custom recombinant protein production or custom antibody production . (mybiosource.com)
  • CLN3
  • 2008) A function retained by the common mutant CLN3 protein is responsible for the late onset of juvenile neuronal ceroid lipofuscinosis (JNCL). (els.net)
  • contrast
  • In contrast, the GAD67 protein remains hydrophilic but has been shown to acquire membrane association by heterodimerization with GAD65. (rupress.org)
  • initiation factor
  • Consistent with these results, we found evidence for the activation of unfolded protein response (UPR) marked by elevated levels of phosphorylated translation initiation factor, eIF2α, increased expression of chaperone proteins such as glucose-regulated protein-78 and activation of caspase-12, a cysteine proteinase in the ER, mediating caspase-3 activation and apoptosis. (oup.com)
  • known
  • CLN4 has no known associated protein. (wikipedia.org)
  • Here, we studied the consequences of genetically inactivating in mice dual-specificity phosphatase 16 ( Dusp16 ), which is known to negatively regulate mitogen-activated protein kinases (MAPKs) and which has never previously been implicated in brain development and disorders. (frontiersin.org)
  • The diverse N-terminal regions of GAD65 and GAD67 share no homology with known proteins, and the crystal structures are not available. (rupress.org)