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  • Bioinformatics
  • Our bioinformatics analyses suggest that they could be involved in plant cell wall degradation (Lin2118 protein from Listeria innocua , PDB code 3oou), symbiotic nitrogen fixation (protein from Chromobacterium violaceum , PDB code 3oio), and either metabolism of plant-derived biomass or nitrogen fixation (protein from Rhodopseudomonas palustris , PDB code 3mn2). (hindawi.com)
  • amino acids
  • Proteins are strings of amino acids that have folded into a specific three-dimensional shape. (elifesciences.org)
  • noticed that when a pair of amino acids (one from each protein in a two-protein complex) co-varied, these two amino acids tended to make contact with each other at the protein-protein interface. (elifesciences.org)
  • We interpret the observed length scale of clustering as a statistical reflection of the functional locality (or modularity) of proteins: amino acids that are near each other on the protein backbone are more likely to contribute to, and collaborate toward, a common subfunction. (prolekare.cz)
  • Most members of this family are comprised of 250 to 300 amino acids and contain two domains: a conserved DNA binding domain (DBD) of ca. 100 residues found at the C-terminus of most regulators and a variable domain thought to be responsible for effector binding or multimerization [ 2 ]. (hindawi.com)
  • Clustering 20 amino acids into a few groups by the proposed greedy algorithm provides a new way to extract features from protein sequences to cover more adjacent amino acids and hence reduce the dimensionality of the input vector of protein features. (biomedcentral.com)
  • cytoplasmic
  • DipZ is a bacterial cytoplasmic membrane protein that transfers reducing power from the cytoplasm to the periplasm so as to facilitate the formation of correct disulphide bonds and c-type cytochromes in the latter compartment. (semanticscholar.org)
  • Ensuing molecular studies demonstrated that lipoic acid inhibited recombinant Ca V 3.2 channels heterologously expressed in human embryonic kidney 293 cells by oxidating specific thiol residues on the cytoplasmic face of the channel. (jneurosci.org)
  • monomeric
  • Important targets of structure alignment are not only monomeric but also oligomeric proteins that sometimes include domain swapping or fusions. (deepdyve.com)
  • antibody
  • If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production , custom recombinant protein production or custom antibody production . (mybiosource.com)
  • Direct ELISAs are based on the stickiness of protein, maybe the antibody just sticks to the agarose whether the reagent is used or not. (bio.net)
  • analyses
  • although only a small portion of these have been confirmed to be bona fide target proteins by biochemical analyses. (frontiersin.org)
  • However, recent population genetic analyses of closely related Drosophila species suggest that protein divergence between species is substantially in excess of the neutral model's predictions , . (prolekare.cz)
  • enzymes
  • For example, in the case of enzymes, a similar (but not necessarily identical) function can be assumed between two proteins if their sequence identity is above 40%, but if the sequence identity drops in between 30-40% then only the first three Enzyme Commission (EC) numbers can be predicted reliably, and only at 90% accuracy level. (biomedcentral.com)
  • Thioredoxin is a critical protein that mediates the transfer of reducing equivalents in vivo and regulates redox sensitive enzymes in several cases. (frontiersin.org)
  • The binding rates of thioredoxin to its targets were very different depending on the use of reducing equivalents by the targets: the enzymes whose activity was controlled by reduction or oxidation of a cysteine pair(s) in the molecule and the enzymes that used reducing equivalents provided by thioredoxin for their catalysis. (frontiersin.org)
  • p>This subsection of the 'Function' section is used for enzymes and indicates the residues directly involved in catalysis. (uniprot.org)
  • ribosome
  • Proteins synthesised at the ribosome (cytoplasm or rough endoplasmic reticulum), mitochondria or chloroplast are transported to their site of function. (springer.com)
  • divergence
  • The dramatic shift in our view of the processes driving protein evolution in Drosophila highlights the deficiency in our understanding of the mechanisms responsible for the observed protein divergence excess. (prolekare.cz)
  • recognition
  • For example, the mechanism of disulfide bonds recognition on the target proteins by Trx and, during the reaction process, the mechanism by which reduced form of Trx react with the oxidized form of the target protein and release it immediately after the dithiol-disulfide exchange reaction is completed. (frontiersin.org)
  • SVM-Fold: a tool for discriminative multi-class protein fold and superfamily recognition. (nih.gov)
  • Molecular Surface Recognition: Determination of Geometric Fit between Proteins and their Ligands by Correlation Techniques. (uni-saarland.de)
  • Interaction
  • The target proteins have been categorized into two groups on the basis of their mode of interaction with Trx. (frontiersin.org)
  • [MJ Ray, nowhere] One of my fellows said 'by introducing stabilizing interaction in proteins (in its core or surface) its enthalpy will increase' This sentence have confused me very much, because as I have learned before reactions (for example protein folding) tend to reduce their enthalpy by releasing heat so stabilized protein (native) relative to intermediate one (for example molten globule state) must have a lower enthalpy. (bio.net)
  • Demonstration of Protein-Protein Interaction Specificity by NMR Chemical Shift Mapping. (uni-saarland.de)
  • Predicted Protein-Protein Interaction Sites from Local Sequence Information. (uni-saarland.de)
  • disulfide
  • The cysteines allow Trx to reduce disulfide bonds on target proteins by catalyzing a dithiol-disulfide exchange reaction, which regulates target activity in several cases. (frontiersin.org)