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  • Mutation
  • In humans, a frameshift mutation in the paired domain of PAX 9 was discovered in those affected with oligodontia. (wikipedia.org)
  • In another experiment performed with the major late promoter (MLP) of adenoviruses from a variety of host species, it was shown that the mutation of the CAAT box and CCAAT sequence, which is thought to play a pivotal role in the (MLP) of subgroup C human adenoviruses, in species with a deficient CAAT sequence. (wikipedia.org)
  • interacts
  • Many of these GTFs do not actually bind DNA, but rather are part of the large transcription preinitiation complex that interacts with RNA polymerase directly. (wikipedia.org)
  • fibroblast
  • This process requires the precise integration of a variety of signaling pathways such as the transforming growth factor type β (TGFβ), fibroblast growth factor (FGF), bone morphogenetic protein (BMP), and Wnt, to achieve the induction, specification, formation and differentiation of the mesoderm layer within a given time and space. (wikipedia.org)
  • Mesoderm
  • Another key player in mesoderm formation is VegT, a maternally and zygotically expressed transcription inducer localized in the vegetal hemisphere. (wikipedia.org)
  • metastasis
  • As the CXCR4 receptor promotes pancreatic cancer growth, migration and metastasis, the targeting of factors that can downregulate CXCR4 has the potential to inhibit pancreatic cancer metastasis. (spandidos-publications.com)