• A National Cancer Data Base (NCDB) analysis of 1797 patients with vulvar cancer who underwent extirpative surgery with confirmed inguinal nodal involvement treated with adjuvant radiotherapy concluded that the addition of adjuvant chemotherapy resulted in a 38% reduction in mortality risk. (medscape.com)
  • Daily adaptive radiotherapy can improve salivary gland sparing and lead to fewer acute toxicities for patients with squamous cell head and neck cancer, according to results from a randomized trial presented at the American Society for Radiation Oncology (ASTRO) 2023 Annual Meeting. (medscape.com)
  • Overall, daily adaptive radiotherapy with 1-mm planning tumor volumes reduced radiation exposure and was associated with less dermatitis and improved salivary outcomes, said lead investigator David Sher, MD , chief of head and neck radiation oncology at the University of Texas Southwestern Medical Center, Dallas. (medscape.com)
  • Adaptive radiotherapy, a concept introduced in the 1990s, updates radiation plans to adjust for anatomic changes in patients and their disease. (medscape.com)
  • The study team randomly assigned 24 patients to receive DART and 26 to receive standard image-guided radiotherapy with radiation delivered in 35 fractions. (medscape.com)
  • 1 Early clinical studies of the EGFR monoclonal antibody in combination with radiotherapy primarily included head and neck squamous cell carcinoma, and the study of its combination with radiation therapy for NSCLC was performed relatively late. (dovepress.com)
  • SEATTLE, Nov. 22, 2010 (Healthcare Sales & Marketing Network) -- Cell Therapeutics, Inc. ("CTI") (Nasdaq and MTA: CTIC) announced the preliminary results of a phase II study of paclitaxel poliglumex (OPAXIO) combined with temozolomide (TMZ) and radiotherapy (RT) in patients with newly diagnosed high-grade gliomas. (salesandmarketingnetwork.com)
  • The goal of definitive radiotherapy is to eradicate intra-thoracic disease while respecting the radiation tolerance of nearby normal structures by minimizing the dose to such structures. (cancernetwork.com)
  • 3-6] Most innovative techniques have focused on conformal treatment delivery with computer assisted three-dimensional therapy planning and, in some cases, intensity-modulated radiotherapy in which more complex treatment planning and delivery can allow the radiation oncologist to have better control of doses to healthy tissues. (cancernetwork.com)
  • Recent developments in surgical treatment, radiotherapy, and chemotherapy have improved patient outcomes. (iiarjournals.org)
  • Radiotherapy, surgery and chemotherapy can all be used to treat cancer of the larynx. (healthlibrary.com)
  • Chemotherapy given with radiotherapy (chemoradiation) may also be a treatment option. (healthlibrary.com)
  • Chemotherapy is sometimes used to help to reduce the size of the cancer before radiotherapy or surgery. (healthlibrary.com)
  • following surgery, chemotherapy (neoadjuvant or adjuvant) and radiotherapy (if applicable) (see section 5.1) - following adjuvant chemotherapy with doxorubicin and cyclophosphamide, in combination with paclitaxel or docetaxel - in combination with adjuvant chemotherapy consisting of docetaxel and carboplatin. (who.int)
  • stereotactic body radiation therapy plus gemcitabine and nab-paclitaxel. (curetoday.com)
  • Presently, the standard first-line treatment for advanced pancreatic cancer is gemcitabine-based chemotherapy. (frontiersin.org)
  • Combination chemotherapy regimens, such as FOLFIRINOX and nab-paclitaxel plus gemcitabine, have demonstrated improved survival rates in advanced pancreatic cancer ( 7 , 8 ). (frontiersin.org)
  • With regard to chemotherapy, for approximately 80% of patients with locally advanced or metastatic illness, gemcitabine or 5-fluorouracil chemotherapy provides a survival time of months, and nab-paclitaxel combined with gemcitabine or FOLFIRINOX provides slight improvements [ 10 , 11 ]. (hindawi.com)
  • MR-Guided Radiation Therapy With Concurrent Gemcitabine/Nab-Paclitaxel Chemotherapy in Inoperable Pancreatic Cancer: A TITE-CRM Phase I Trial. (wustl.edu)
  • NAC regimens were paclitaxel (n = 6) or gemcitabine/docetaxel (n = 4). (lvhn.org)
  • Anticancer therapy that consisted of radiation to the stomach and daily capecitabine and weekly paclitaxel was begun 5 days after discharge. (cdc.gov)
  • 1 - 3 In patients with node-negative small tumors, chemotherapy burden can be de-escalated by administering weekly paclitaxel for 3 months and concurrent trastuzumab for 1 year. (jnccn.org)
  • If the addition of TAK228 to weekly paclitaxel chemotherapy is shown to significantly improve this statistically, and adverse events and quality of life are not significantly worse than standard treatment, then TAK228 plus weekly paclitaxel could potentially be taken forward within the context of a larger phase III trial. (biomedcentral.com)
  • 3 Although myelosuppression is the major toxicity for docetaxel, 4 paclitaxel is more likely to be associated with dose-limiting peripheral neuropathy. (jnccn.org)
  • docetaxel, 42%) in small nonrandomized studies for patients who had not undergone prior chemotherapy for R/M HNSCC. (jnccn.org)
  • Biocon Biologics Ltd), BT-ON014 - in combination with docetaxel for the treatment of those patients who have not received chemotherapy for their metastatic disease - in combination with an aromatase inhibitor for the treatment of postmenopausal patients with hormone-receptor positive MBC, not previously treated with trastuzumab. (who.int)
  • Neoadjuvant chemotherapy has evolved rapidly in recent decades, giving patients with advanced disease more possibilities for surgical resection and radiation therapy [ 12 ]. (hindawi.com)
  • We investigated whether the use of ACEI/ARBs affects the clinical outcomes of primary breast cancer patients receiving taxane and anthracycline-based neoadjuvant chemotherapy. (jcancer.org)
  • We included 1449 patients with diagnosis of invasive primary breast cancer diagnosed at the MD Anderson Cancer Center between 1995 and 2007 who underwent neoadjuvant chemotherapy. (jcancer.org)
  • No differences in pCR and survival outcomes were seen between ACEI/ARB users and non-users among breast cancer patients receiving neoadjuvant chemotherapy. (jcancer.org)
  • Neoadjuvant chemotherapy for primary cutaneous/soft tissue angiosarcom" by Jacqueline Oxenberg DO, Nikhil I Khushalani et al. (lvhn.org)
  • Neoadjuvant chemotherapy for primary cutaneous/soft tissue angiosarcoma: Determining tumor behavior prior to surgical resection. (lvhn.org)
  • BACKGROUND: Given the propensity for hematogenous metastases, neoadjuvant chemotherapy (NAC) could treat occult metastatic disease early, potentially improving survival and better defining which primary angiosarcomas (AS) benefit from surgical resection. (lvhn.org)
  • 2 cm in diameter, as adjuvant therapy following neoadjuvant chemotherapy and surgery (see sections 4.4 and 5.1). (who.int)
  • Hence, continued advancements in diagnostic techniques, chemotherapy and radiation therapy regimens, targeted therapy strategies, and cachexia treatments will be critical for improving patient outcomes ( Figure 1 ). (frontiersin.org)
  • After surgical debulking and volume-directed irradiation of the pelvis/para-aortic lymph nodes, treatment was randomized to compare recurrence-free survival (RFS) and toxicity between two chemotherapy regimens for the treatment of women with advanced stage endometrial carcinoma. (nih.gov)
  • Chemotherapy regimens for esophageal cancer have been found to work better when drugs are combined. (epnet.com)
  • as monotherapy for the treatment of those patients who have received at least two chemotherapy regimens for their metastatic disease. (who.int)
  • She also went through two weeks of radiation and in between those appointments, met with a pain management specialist, radiation oncologist and orthopedic oncologist for test after test after test. (caringbridge.org)
  • Moderator Beth Beadle, MD, PhD, a radiation oncologist at Stanford University, California, noted the "very convincing difference" between the two arms but wondered why xerostomia differences weren't more pronounced. (medscape.com)
  • Her gynecologist referred her back to her breast specialist, but the breast specialist commented that she'd never seen anything like that and referred her back to her radiation oncologist. (curetoday.com)
  • That night, my radiation oncologist called me and said, 'I need to get you in here. (curetoday.com)
  • A medical oncologist will determine how many cycles of chemotherapy are needed and what combination of drugs will work best. (epnet.com)
  • In addition, a growing number of clinical cases have found that pancreatic cancer exhibits significant resistance to traditional treatment options, including chemotherapy, radiation, and immunotherapy [ 6 , 7 ]. (hindawi.com)
  • By building on the proven concept of conventional chemoradiation for patients with locally advanced NSCLC with a subsequent radiation dose intensification to residual disease with SBRT concurrent with immunotherapy, we hope address the issues of metastatic and local failures. (frontiersin.org)
  • Novel approaches to immunotherapy, targeted therapy and combinations with standard chemotherapy are all areas of current research interest," says an expert at Dana-Farber Cancer Institute Sarcoma Center in Boston. (curetoday.com)
  • 4. Patients who had recurred from Stage I/II/III after complete surgery or had gross incomplete resections can be included if they didn't receive treatment with any chemotherapy, radiation therapy, immunotherapy, targeted therapy, or investigational agents. (who.int)
  • American Society for Radiation Oncology (ASTRO) 2023 Annual Meeting: Abstract LBA 08 . (medscape.com)
  • An early dose-finding study by the Radiation Therapy Oncology Group (RTOG) 7301 study was conducted from 1973 to 1978 and studied four different doses and schedules: 40 Gy split course, 40 Gy continuously, 50 Gy, and 60 Gy. (frontiersin.org)
  • In an upcoming trial, The Brown University Oncology Group and Cell Therapeutics are planning to test PPX with radiation in the subset of patients with GBM and MGMT positive (non-silenced MGMT expression). (salesandmarketingnetwork.com)
  • International Journal of Radiation Oncology Biology Physics. (wustl.edu)
  • Unadjusted median survival with and without adjuvant chemotherapy was 44.0 versus 29.7 months, respectively (P=0.001). (medscape.com)
  • Due to similar behavior as ovarian carcinoma, adjuvant abdominal radiation was proposed. (wikibooks.org)
  • Patients received adjuvant paclitaxel for 12 weeks with trastuzumab, and trastuzumab was continued for 1 year. (johnshopkins.edu)
  • In order to achieve a more effec- were recommended postoperative radiation and adjuvant tive and individualised chemotherapeutic treatment of breast chemotherapy. (lu.se)
  • Patients and Methods: A total of 20 patients with bone metastases from uterine cervical cancer received radiation therapy to the pelvis. (iiarjournals.org)
  • AFP ≥ 10,000 ng/mL - Patients who received prior radiation therapy (RT) for treatment of germ cell tumor are eligible for this study as long as there is evidence of progressive disease determined by tumor markers or other sites of metastases outside of the radiated site. (stanfordhealthcare.org)
  • Radiation must be completed prior to starting chemotherapy with the exception of brain metastases where chemotherapy and radiation can be given concurrently. (stanfordhealthcare.org)
  • Intraperitoneal Chemotherapy for Ovarian Cancer: Where Are We Now? (jnccn.org)
  • The GOG-0212 study is a randomized, multicenter, open label Phase 3 trial of either monthly Opaxio or paclitaxel for up to 12 consecutive months compared to surveillance among women with advanced ovarian cancer who have no evidence of disease following first-line platinum-taxane based therapy. (salesandmarketingnetwork.com)
  • The standard initial treatment for ovarian cancer is surgery and platinum-based chemotherapy and potentially maintenance therapy with avastin or inhibitors of poly-ADP ribose polymerase (PARP). (biomedcentral.com)
  • Epirubicin may increase your risk for developing leukemia (cancer of the white blood cells), especially when it is given in high doses or together with certain other chemotherapy medications. (medlineplus.gov)
  • In cancer cells that survive the initial explosions, the bursting nanobubbles greatly magnify the local doses of both chemotherapy drugs and radiation. (medicalxpress.com)
  • Your chances of getting peripheral neuropathy go up with higher doses of chemotherapy, combination chemotherapy, or several rounds of treatment. (webmd.com)
  • Sparing these normal tissues permits the delivery of higher-radiation doses to the tumor. (cancernetwork.com)
  • Studies that compare the distribution of radiation doses for lung cancer show that proton radiation is superior, even when factors such as respiratory motion are considered. (cancernetwork.com)
  • Because of their their mass (about 1800 times that of an electron) and charge, proton beams can be controlled in three dimensions so that radiation doses can be more accurately deposited within target volumes while the dose to surrounding non-targeted tissues is often minimized-or even eliminated. (cancernetwork.com)
  • In studies spanning more than four decades, Rubin and several collaborators identified the clinicopathologic courses of radiation injury in organs and tissues throughout the body and identified tolerance doses for those organs. (cancernetwork.com)
  • INTERVENTIONS Treatment consisted of weekly 80-mg/m2 doses of paclitaxel administered concurrently with trastuzumab intravenously for 12 weeks, followed by trastuzumab monotherapy for 39 weeks. (johnshopkins.edu)
  • Four sites across the United States are enrolling patients with locally advanced or metastatic pancreatic cancer to see if a novel drug combined with standard-of-care chemotherapy bests chemotherapy alone in survival outcomes and responses to treatment. (curetoday.com)
  • When used alone, chemotherapy is not an effective treatment for esophageal cancer or long-term survival. (epnet.com)
  • Tell your doctor if you have or have ever had any type of heart disease or radiation (x-ray) therapy to the chest area. (medlineplus.gov)
  • Then, in 2009 Monk defined the systemic therapy standard of care of recurrent cervical cancer being the combination of a platinum medication and paclitaxel (taxane). (wikipedia.org)
  • Chemotherapy and radiation therapy are the cornerstone of therapy for unresectable pancreatic cancer. (frontiersin.org)
  • Aim: To determine the role of radiation therapy for patients with bone metastasis from uterine cervical cancer and identify an optimal radiation regimen. (iiarjournals.org)
  • Thirteen patients underwent chemotherapy during and/or following radiation therapy. (iiarjournals.org)
  • Results: In 18 of 20 patients, the primary tumors disappeared or were markedly reduced after radiation therapy. (iiarjournals.org)
  • Conclusion: Radiation therapy is effective for relief of pelvic symptoms in patients with bone metastasis from uterine cervical cancer. (iiarjournals.org)
  • Even in such patients, radiation therapy has been positively used with palliative intent to relieve severe symptoms, including bleeding and pain, via primary tumor control. (iiarjournals.org)
  • Even at 2 years after radiation therapy, 15% of patients had grade 2 swallowing dysfunction and 8% had progressive dysphagia, so their swallowing is going to continue to get worse. (ascopost.com)
  • Treatment usually involves removing the uterus, ovaries, and fallopian tubes and sometimes involves removing nearby lymph nodes, often followed by radiation therapy and sometimes by chemotherapy or hormone therapy. (merckmanuals.com)
  • Over the last 17 years, stereotactic body radiation therapy (SBRT) has shown a high degree of safety and local control for stage I lung cancers and other localized malignancies. (frontiersin.org)
  • However, for patients with more locally advanced NSCLC, 5-year OS after treatment with definitive radiation therapy and concurrent chemotherapy remains modest, at approximately 15-20% ( 4 ). (frontiersin.org)
  • Presently, stage III lung cancer is managed with a combination of chemotherapy, radiation therapy, and sometimes surgery but the two major challenges in improving outcomes of the treatment of this disease remain local control and metastatic spread. (frontiersin.org)
  • Standard therapy for patients with malignant brain tumors, like glioblastoma multiforme (GBM) employs a chemotherapy drug called temozolomide (TMZ) and radiation therapy (RT) and results in a PFS of 54% at 6 months. (salesandmarketingnetwork.com)
  • Radiation therapy often follows surgery. (cancer.org)
  • Adaptive radiation therapy. (wustl.edu)
  • Clinical Complete Response in Patients With Rectal Adenocarcinoma Treated With Short-Course Radiation Therapy and Nonoperative Management. (wustl.edu)
  • For nonseminomas, it may be used with radiation therapy (called chemoradiation). (epnet.com)
  • Beal K , Hudis C , Norton L . Radiation pneumonitis in breast cancer patients treated with taxanes: Does sequential radiation therapy lower the risk? (qscience.com)
  • Proton Radiation Therapy for Lung Cancer: Is There Enough Evidence? (cancernetwork.com)
  • Proton radiation for cancer offers the ability to conform the high-dose region of radiation therapy to the tumor while reducing the dose of radiation to adjacent normal tissues. (cancernetwork.com)
  • Tumor control rates with photon radiation therapy, however, continue to be disappointing, in part because of the dose-limiting constraints associated with these normal structures. (cancernetwork.com)
  • RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. (stanfordhealthcare.org)
  • It is not yet known whether high-dose radiation therapy is more effective than standard-dose radiation therapy when given together with combination chemotherapy with or without cetuximab in treating patients with non-small cell lung cancer. (stanfordhealthcare.org)
  • PURPOSE: This randomized phase III trial is studying high-dose or standard-dose radiation therapy given together with chemotherapy with or without cetuximab to see how well they work in treating patients with newly diagnosed stage III non-small cell lung cancer that cannot be removed by surgery. (stanfordhealthcare.org)
  • Radiation and hormone therapy were administered per standard guidelines after completion of the 12 weeks of chemotherapy. (johnshopkins.edu)
  • Chemotherapy and targeted therapy are used to treat esophageal cancer. (epnet.com)
  • Chemotherapy for esophageal cancer is most often used in combination with radiation therapy (called chemoradiation). (epnet.com)
  • Unlike chemotherapy, targeted therapy drugs attack cancer cells without harming healthy cells. (epnet.com)
  • The use of a treatment protocol consisting of a mucositis solution associated with low-level laser therapy effectively resolved a case of severe chemotherapy-induced oral mucositis. (bvsalud.org)
  • This randomized phase III trial studies how well standard-dose combination chemotherapy works compared to high-dose combination chemotherapy and stem cell transplant in treating patients with germ cell tumors that have returned after a period of improvement or did not respond to treatment. (cincinnatichildrens.org)
  • It is not yet known whether high-dose combination chemotherapy and stem cell transplant are more effective than standard-dose combination chemotherapy in treating patients with refractory or relapsed germ cell tumors. (cincinnatichildrens.org)
  • Radiation is a feasible option for patients with squamous cell carcinoma of the anterior nasal cavity mucosa who refuse rhinectomy, according to our recent research. (mskcc.org)
  • Together with our colleagues, we analyzed the results for 11 patients who refused surgery and were treated with radiation, with or without chemotherapy, at Memorial Sloan Kettering Cancer Center between January 2000 and July 2018. (mskcc.org)
  • In his study regarding cervical cancer, Monk reviewed several patients which had uterine sarcoma with cervical involvement, a poor response to preoperative radiation, and a poor response to preoperative radiation. (wikipedia.org)
  • Results of his study indicated that radical hysterectomy after radiation is morbid but might be effective in context of treating patients with small recurrent cervical tumors, cervical cancer that responds poorly to radiation, large cervical tumors, patients unable to undergo brachytherapy for cervical cancer, and uterine sarcomas involving the cervix. (wikipedia.org)
  • The selection of effective chemotherapies based on the evaluation of biomarkers (i.e., "tailor-made chemotherapy") can improve the clinical outcome of NSCLC patients ( 3 ). (aacrjournals.org)
  • This is the first clinical trial evaluating the safety and effectiveness of the addition of PPX to standard TMZ and radiation for patients with GBM," said Dr. Suriya Jeyapalan. (salesandmarketingnetwork.com)
  • Lateral Pelvic Nodal Management and Patterns of Failure in Patients Receiving Short-Course Radiation for Locally Advanced Rectal Cancer. (wustl.edu)
  • Eligible patients included Stage I-II UPSC and CC. Over 50% of failures for UPSC/CC patients were within the radiation field. (wikibooks.org)
  • Initially in paclitaxel treated patients and, after May 2002, all patients received granulocyte growth factor with each cycle. (nih.gov)
  • Of 659 patients enrolled following surgery, 552 eligible patients were randomized to chemotherapy after irradiation. (nih.gov)
  • At the bottom of the page, it says that less than 1% of patients that receive radiation may have some of these other problems," Carpenter recalls. (curetoday.com)
  • OBJECTIVE To determine the cardiac safety of paclitaxel with trastuzumab and the utility of LVEF monitoring in patients with node-negative, ERBB2-positive breast cancer. (johnshopkins.edu)
  • Prior chemotherapy must have included at least an anthracycline and a taxane unless patients are unsuitable for these treatments. (who.int)
  • 5 reported that 78% of chemotherapy patients presented with mucositis at some point during treatment. (bvsalud.org)
  • Although some progress had been made there is still significant tumors that exist even after the chemo and radiation she received over the last six months. (caringbridge.org)
  • Chemotherapy and radiation are commonly used to treat the residual portions of these tumors, but some tumors become resistant to chemoradiation. (medicalxpress.com)
  • Given that 55% of GBM tumors express MGMT, a gene responsible for inactivating the effectiveness of allkylating chemotherapy agents like TMZ, we are exploring whether or not PPX results in this trial were associated with anti-tumor activity in this otherwise TMZ resistant population which could lead to an accelerated clinical development path for PPX in MGMT+ GBM. (salesandmarketingnetwork.com)
  • Based on preclinical studies, it appears that Opaxio is preferentially distributed to tumors due to their leaky blood vessels and trapped in the tumor bed, allowing significantly more of the dose of chemotherapy to localize in the tumor than with standard paclitaxel. (salesandmarketingnetwork.com)
  • Clinical experience confirms the feasibility of proton radiation for early-stage non-small-cell lung cancers, and clinical trials are being conducted in locally advanced tumors: To date, evidence indicates that proton radiation should be further explored. (cancernetwork.com)
  • Tighter planning of tumor volumes translated to significantly less radiation to nearby salivary glands, including ipsilateral parotid glands (11.5 Gy with DART vs 16 Gy) and ipsilateral (42.2 Gy vs 56.3 Gy), and contralateral (28.2 Gy vs 36.5 Gy) submandibular glands. (medscape.com)
  • The approach combines traditional chemotherapy drugs with a new method for irradiating the tumor. (news-medical.net)
  • Rather than delivering radiation from an external beam that travels through healthy tissue, the treatment implants radioactive iodine-131 directly into the tumor within a gel-like depot that protects healthy tissue and is absorbed by the body after the radiation fades away. (news-medical.net)
  • The current leading treatment combines chemotherapy, which keeps cells in a stage of reproduction vulnerable to radiation for longer periods of time, with a beam of radiation targeted at the tumor. (news-medical.net)
  • This approach, however, is ineffective unless a certain threshold of radiation reaches the tumor. (news-medical.net)
  • But because titanium blocks all radiation other than gamma rays, which travel far outside the tumor, it can only remain within the body for a short period of time before damage to surrounding tissue begins to defeat the purpose. (news-medical.net)
  • The iodine-131 emits beta radiation, which penetrates the biogel and deposits almost all its energy into the tumor without reaching the surrounding tissue. (news-medical.net)
  • Paclitaxel poliglumex (PPX) is one of the most potent radiation sensitizers reported in the literature, selectively increasing tumor sensitivity to radiation up to 8 to 10 fold in animal models. (salesandmarketingnetwork.com)
  • Treatment usually starts with chemotherapy (chemo) to try to shrink the tumor. (cancer.org)
  • Once inside the tumor cell, enzymes metabolize the protein polymer, releasing active paclitaxel. (salesandmarketingnetwork.com)
  • Unlike standard radiosensitizing agents, Opaxio appears tumor selective and does not appear to enhance radiation toxicity to normal tissues. (salesandmarketingnetwork.com)
  • Trastuzumab, when used with chemotherapy, may help stop tumor growth in cancers with an excess amount of HER2. (epnet.com)
  • Chemotherapy-induced mucositis is one of the most important undesirable side effects of cancer treatment, promoting the worst cases of morbidity, increasing length of hospital stay, and frequently reducing the odds of controlling the tumor and the patient's life expectancy 1 . (bvsalud.org)
  • All of the doctors indicated that the standard of care for this type of treatment was chemotherapy with Paclitaxel, Carboplatin, and Avastin. (caringbridge.org)
  • peritoneal cancers undergo treatment consisting of both surgical debulking and chemotherapy. (jnccn.org)
  • Another study found that one-fifth of people with breast cancer treated with taxane-based chemotherapy had peripheral neuropathy after treatment. (webmd.com)
  • In the new paper, Schaal and his collaborators in the Chilkoti laboratory tested the new treatment in concert with paclitaxel, a commonly used chemotherapy drug, to treat various mouse models of pancreatic cancer. (news-medical.net)
  • While a proportion of women are cured by this approach, the vast majority will relapse and become resistant to platinum chemotherapy either initially or on subsequent treatment. (biomedcentral.com)
  • Various photon radiation techniques have been tried in order to effect a therapeutic advantage, among them hyperfractionation (multiple treatments per day), accelerated fractionation (shorter treatment periods), and dose escalation. (cancernetwork.com)
  • This ability to spare normal tissues is an important consideration: The greater the extent to which the physician can reduce or eliminate the radiation dose to normal tissues, the lesser the likelihood that treatment will need to be compromised because of unacceptable side effects. (cancernetwork.com)
  • PMID 9422561 -- "Effective treatment of stage I uterine papillary serous carcinoma with high dose-rate vaginal apex radiation (192Ir) and chemotherapy. (wikibooks.org)
  • Radiation treatment. (abcbnews.com)
  • The following are the objectives of treatment: Treat the illness that is the root of the issue (for example, radiation or surgery to shrink a tumour that is pressing on a nerve). (abcbnews.com)
  • Angelia Carpenter of New London, Missouri, developed angiosarcoma of the breast five years after completing treatment for breast cancer, which included a lumpectomy, chemotherapy and radiation. (curetoday.com)
  • Generally, any positive effects from chemotherapy treatment alone are short-lived. (epnet.com)
  • 2. Past medical history of ILD/pneumonitis, drug-induced ILD, radiation pneumonitis that required steroid treatment, or any evidence of clinically active ILD/pneumonitis. (who.int)
  • BT-ON014 trade name] treatment should only be initiated by a health care provider experienced in the administration of cytotoxic chemotherapy (see section 4.4), and should be administered by a health care provider only. (who.int)
  • The monitoring and treatment of oral mucositis lesions in children and adolescents undergoing chemotherapy are necessary to prevent the patient from suffering from induced comorbidities. (bvsalud.org)
  • According to treatment guidelines in the regional care pro- recur in spite of chemotherapy. (lu.se)
  • If you've had taxane-based chemotherapy or other treatments for breast cancer , you may form a condition called peripheral neuropathy . (webmd.com)
  • In one study, just over 40% of participants reported symptoms of neuropathy 2 years after taxane-based chemotherapy to treat breast cancer . (webmd.com)
  • How Does Taxane-Based Chemotherapy Cause Peripheral Neuropathy? (webmd.com)
  • There are a few types of taxane-based chemotherapies. (webmd.com)
  • CONCLUSIONS AND RELEVANCE Cardiac toxic effects from paclitaxel with trastuzumab, manifesting as grade 3 or 4 LVSD or asymptomatic LVEF decline, were low. (johnshopkins.edu)
  • Prior to the advent of cytotoxic chemotherapy, lung cancer at all stages was treated surgically or by radiation alone ( 5 , 6 ). (frontiersin.org)
  • Other chemotherapy drugs, in addition to taxanes, can trigger neuropathy. (webmd.com)
  • Epirubicin should be given only under the supervision of a doctor with experience in the use of chemotherapy medications. (medlineplus.gov)
  • Epirubicin comes as a solution (liquid) to be injected intravenously (into a vein) by a doctor or nurse in a medical facility along with other chemotherapy medications. (medlineplus.gov)
  • Giving colony-stimulating factors, such as filgrastim or pegfilgrastim, and certain chemotherapy drugs, helps stem cells move from the bone marrow to the blood so they can be collected and stored. (cincinnatichildrens.org)
  • They may work when standard chemotherapy drugs have not worked. (epnet.com)
  • Opaxio (paclitaxel poliglumex, CT-2103), is an investigational, biologically enhanced chemotherapeutic that links paclitaxel, the active ingredient in Taxol , to a biodegradable polyglutamate polymer, which results in a new chemical entity. (salesandmarketingnetwork.com)
  • Prolonged complete response obtained by radiation and chemotherapy with paclitaxel in a case of recurrent gastric cancer in the rectovesical pouch]. (elsevierpure.com)
  • Dive into the research topics of '[Prolonged complete response obtained by radiation and chemotherapy with paclitaxel in a case of recurrent gastric cancer in the rectovesical pouch]. (elsevierpure.com)
  • Giving chemotherapy before a stem cell transplant stops the growth of cancer cells by stopping them from dividing or killing them. (cincinnatichildrens.org)
  • Lapotko said quadrapeutics differs from other developmental cancer treatments in that it radically amplifies the intracellular effect of drugs and radiation only in cancer cells . (medicalxpress.com)
  • Plasmonic nanobubbles act as a "mechanical drug" against cancer cells that cannot be surgically removed and are otherwise resistant to radiation and chemotherapy. (medicalxpress.com)
  • All three effects-mechanical cell destruction, intracellular drug ejection and radiation amplification-occur only in cancer cells and do not harm vital healthy cells nearby. (medicalxpress.com)
  • We literally bring surgery, chemotherapies and radiation therapies inside cancer cells. (medicalxpress.com)
  • The gold nanoclusters amplify the deadly effects of radiation only inside cancer cells, even when the overall dose to the patient is just a few percent of the typical clinical dose. (medicalxpress.com)
  • Other cancer treatments that can trigger peripheral neuropathy include breast cancer surgery or radiation. (webmd.com)
  • The current standard of care for locally advanced non-small cell lung cancer (NSCLC) includes radiation, chemotherapy, and surgery in certain individualized cases. (frontiersin.org)
  • Chae YK, Brown EN, Lei X, Melhem-Bertrandt A, Giordano SH, Litton JK, Hortobagyi GN, Gonzalez-Angulo AM, Chavez-MacGregor M. Use of ACE Inhibitors and Angiotensin Receptor Blockers and Primary Breast Cancer Outcomes. (jcancer.org)
  • Chemotherapy uses drugs to kill testicular cancer cells. (epnet.com)
  • Even with chemotherapy, testicular cancer can come back. (epnet.com)
  • The stem cells are frozen until all the cancer is killed using high-dose chemotherapy. (epnet.com)
  • Available at: https://www.cancer.org/cancer/testicular-cancer/treating/chemotherapy.html. (epnet.com)
  • High-dose chemotherapy and stem cell transplant for testicular cancer. (epnet.com)
  • note that prior chemotherapy for a different cancer is allowable. (stanfordhealthcare.org)
  • The cancer was caught very early, and after a lumpectomy and six weeks of radiation, "I was on my way," she says. (curetoday.com)
  • Far fewer than 1% - 0.05% to 0.3% - of breast cancer survivors who have breast-conserving surgery followed by radiation later develop secondary breast angiosarcoma, according to study findings published in the journal Clinical Sarcoma Research in 2017. (curetoday.com)
  • Chemotherapy for esophageal cancer may given before or after surgery . (epnet.com)
  • la prise en charge du cancer col métastatique s'est enrichie depuis 2017 par la disponibilité des thérapies ciblées dans notre pays. (bvsalud.org)
  • Cette étude avait pour objectifs de déterminer les caractéristiques épidémiologiques, cliniques et thérapeutiques des patientes prises en charge pour cancer du col métastatique dans notre structure. (bvsalud.org)
  • In April 2019 Mary had to have cataract surgery on both eyes as a byproduct and common side effect of chemotherapy. (caringbridge.org)
  • Sometimes, more chemo may be given after surgery but before radiation. (cancer.org)
  • First in 1999, he contributed to the integration of chemotherapy in treating locally advanced disease with radiation. (wikipedia.org)
  • Your doctor may give you one of these or combine them with other chemotherapy medications. (webmd.com)
  • Astera, which is approximately one-hour north of Philadelphia and one-hour south of New York City, becomes one of four sites assessing the safety and efficacy of combining PD-L1 targeting high-affinity natural killer (NK) cells with aldoxorubicin HCl, N-803 and standard-of-care chemotherapy agents versus standard-of-care chemotherapy alone in this patient population. (curetoday.com)
  • 23% S versus 40% NAC-S had prior radiation (RT). (lvhn.org)
  • The case-group underwent oral hygiene control associated with the use of chamomile tea before starting the first cycle of chemotherapy, while the control group, there were no previous guidelines and prescriptions. (bvsalud.org)
  • To administer quadrapeutics, the team uses four clinically approved components: chemotherapy drugs, radiation, near-infrared laser pulses of low energy and colloidal gold. (medicalxpress.com)
  • There are a variety of chemotherapy drugs. (epnet.com)
  • The first component of quadrapeutics is a low dose of a clinically validated chemotherapy drug. (medicalxpress.com)
  • Smith didn't recall learning about the risk for secondary cancers before she started radiation, but even if she had, it wouldn't have changed her care. (curetoday.com)