Mice, TransgenicGene ExpressionTransfectionCell Line, TumorSignal TransductionRNA, MessengerMolecular Sequence DataApoptosisCell LineUp-RegulationTranscription FactorsGene Expression Regulation, NeoplasticImmunohistochemistryMutationBlotting, WesternGene Expression RegulationReverse Transcriptase Polymerase Chain ReactionBase SequenceCells, CulturedPromoter Regions, GeneticRNA, Small InterferingDNA-Binding ProteinsAmino Acid SequenceCell ProliferationPhosphorylationPhenotypeDown-RegulationProtein BindingTumor Cells, CulturedNuclear ProteinsMembrane ProteinsRNA InterferenceCarrier ProteinsProto-Oncogene ProteinsAdenoviridaeTumor Suppressor Protein p53Protein-Serine-Threonine KinasesTranscription, GeneticCell DivisionMice, Inbred C57BLRecombinant Fusion ProteinsGene Expression Regulation, EnzymologicGene Knockdown TechniquesProto-Oncogene Proteins c-bcl-2DNA PrimersCell DifferentiationNeoplasm ProteinsRecombinant ProteinsGenetic VectorsCloning, MolecularTrans-ActivatorsBreast NeoplasmsHeLa CellsReceptor, erbB-2Plants, Genetically ModifiedRepressor ProteinsCell CycleGene AmplificationEnzyme ActivationCell SurvivalDNA, ComplementaryCell Cycle ProteinsCell MovementIntracellular Signaling Peptides and ProteinsCyclin D1Protein Structure, TertiaryNeoplasm InvasivenessTranscriptional ActivationCell Transformation, NeoplasticGene Expression Regulation, DevelopmentalGene Expression ProfilingSequence Homology, Amino AcidPlasmidsProtein TransportGreen Fluorescent ProteinsTime FactorsCell NucleusTransgenesImmunoblottingMicroRNAsHEK293 CellsSaccharomyces cerevisiaeMice, NudeImmunoprecipitationDisease Models, AnimalProto-Oncogene Proteins c-aktBlotting, NorthernAdaptor Proteins, Signal TransducingSaccharomyces cerevisiae ProteinsMice, KnockoutCOS CellsHomeodomain ProteinsTumor Markers, BiologicalModels, BiologicalProtein IsoformsTwo-Hybrid System TechniquesFibroblastsGene SilencingGenes, ReporterProteins