Tumor Suppressor Protein p53Tumor Suppressor ProteinsGenes, Tumor SuppressorApoptosisProto-Oncogene Proteins c-mdm2Cell Line, TumorCyclin-Dependent Kinase Inhibitor p21Genes, p53Von Hippel-Lindau Tumor Suppressor ProteinNuclear ProteinsProtein BindingCell LineTumor Suppressor Protein p14ARFTumor Cells, CulturedDNA DamageTransfectionMolecular Sequence DataProto-Oncogene ProteinsMutationDNA-Binding ProteinsCyclinsCell CycleRetinoblastoma ProteinTranscriptional Activationbcl-2-Associated X ProteinPhosphorylationSignal TransductionProto-Oncogene Proteins c-bcl-2Transcription FactorsCell Cycle ProteinsBase SequenceGene Expression Regulation, NeoplasticAmino Acid SequencePromoter Regions, GeneticTranscription, GeneticCell ProliferationBlotting, WesternCells, CulturedDown-RegulationUbiquitin-Protein LigasesCell DivisionApoptosis Regulatory ProteinsBinding SitesRNA, MessengerAdenovirus E1B ProteinsHeLa CellsFibroblastsCell SurvivalProtein Structure, TertiaryGene Expression RegulationCaspasesOncogene Proteins, ViralDNAUltraviolet RaysCaspase 3NeoplasmsMice, KnockoutCell NucleusRecombinant Fusion ProteinsRNA, Small InterferingUbiquitinsTrans-ActivatorsNeurofibromin 2Protein-Serine-Threonine KinasesDNA PrimersCell Transformation, NeoplasticProteasome Endopeptidase ComplexRecombinant ProteinsPrecipitin TestsAdenomatous Polyposis Coli ProteinNeoplasm ProteinsAntigens, Polyomavirus TransformingModels, BiologicalCyclin-Dependent Kinase Inhibitor p16E2F1 Transcription FactorConsensus SequenceCarrier ProteinsProteinsRNA InterferenceE2F Transcription FactorsSpodopteraPTEN PhosphohydrolaseRepressor ProteinsAcetylationGenes, SuppressorReverse Transcriptase Polymerase Chain ReactionEnzyme ActivationSerineGene SilencingHCT116 CellsIn Situ Nick-End LabelingPapillomaviridaeLigasesMice, Inbred C57BLMembrane ProteinsTumor Necrosis Factor-alphaImmunohistochemistryG1 PhaseFlow CytometryMitochondria