Oxygen sensor cell respiration. Medical search. Frequent questions

Reactive oxygen species interacting with cysteine residues can alter protein function. (nature.com)
Reactive oxygen species (ROS) are typically defined as biologically reactive molecules or ions formed by reduction of oxygen. (nature.com)
Cancer cells try to avoid the overproduction of reactive oxygen species by metabolic rearrangements. (hindawi.com)
Reactive oxygen species (ROS), generated as consequence of oxidative metabolism, activate signal transduction pathways, which contribute to cellular homeostasis [ 1 ]. (hindawi.com)
While factors such as nitric oxide modulate HPV, reactive oxygen species (ROS) have been suggested to act as essential mediators in HPV. (ersjournals.com)
Pathological fission in somatic cells generates reactive oxygen species and triggers cell death. (bvsalud.org)
Mitochondria, a powerhouse of the cell, are rich in a large number of enzymes, which not only participate in cellular oxidative phosphorylation and ATP synthesis, but also regulate intracellular calcium ions and reactive oxygen species to maintain cellular homeostasis. (biomedcentral.com)
During the early stage of cerebral I/R injury, significantly-swollen mitochondria decrease adenosine triphosphate (ATP) and produce excessive reactive oxygen species (ROS) and oxidative stress, finally resulting in cell death [ 6 ]. (biomedcentral.com)
The consequences for the cell can be dramatic mainly due to a reduction in the amount of ATP produced and an increase in the levels of reactive oxygen species. (bmglabtech.com)
Increased levels of reactive oxygen species can damage the molecular fabric of the cell including lipids, proteins, and DNA. (bmglabtech.com)
1 Excessive production of reactive oxygen species can lead to oxidative stress which is associated with inflammation and neurodegenerative disease. (bmglabtech.com)
In addition to less ATP production and higher levels of reactive oxygen species, mitochondria in the brains of individuals with Alzheimer's disease show mitochondrial abnormalities that include altered shape, decreased density, and impaired respiration. (bmglabtech.com)
Immune cells release reactive oxygen species (ROS) in response to cytokine upregulation [29]. (encyclopedia.pub)
We previously identified organochalcogens (organoselenium -tellurium compounds) to act as 'sensor/effector' catalysts of reactive oxygen species (ROS) particularly in a specific tumor-to-normal cell fashion across various malignancy cell types including CLL [7 8 These substances exploited the aberrant redox equilibrium of enhanced radical production and reduced glutathione (GSH) buffer levels in CLL cells as their selective vulnerability by increasing the elevated ROS levels towards a cytotoxic threshold. (tech-strategy.org)

Since the consumption of the oxygen present in the medium correlates directly with aerobic cell respiration, i.e. the production of energy through the breakdown of glucose to carbon dioxide and water, it serves as a measure of cell vitality. (gesundheitsindustrie-bw.de)
Mitochondria, which generate ATP through aerobic respiration, also have important noncanonical functions. (bvsalud.org)
They carry out aerobic respiration, a process that involves the breakdown of glucose and other fuel molecules to produce ATP through a series of interconnected reactions, including the citric acid cycle and the mitochondrial electron transport chain. (bmglabtech.com)
On the onset of hyperglycemia, however, elevated mitochondrial aerobic respiration and activity of the electron transport chain, as well as advanced glycated end products, aggravates oxidative stress, which presents another activator of inflammatory cascades mediated by NF-κB, cAMP-regulated element-binding protein, and activator protein 1 [31]. (encyclopedia.pub)
Although basal mitochondrial respiration (OCR) and maximal respiratory capacity were not affected by TCL1 overexpression it mediated a reduced aerobic glycolysis (lactate production) and a higher fraction of oxygen consumption coupled to ATP-synthesis. (tech-strategy.org)

These are as follows: sustained proliferative signalling, cell death resistance, replicative immortality, genome instability and increased mutations, tumour-promoted inflammation, insensibility to growth repressors, deregulation of cellular energetics, evasion of immune destruction, induction of metastasis, and promotion of angiogenesis. (hindawi.com)
Just like our own cells, plants and algae also respire, consuming oxygen as a form of cellular metabolism. (weebly.com)
Absent retinol, cellular respiration (energy production and oxygen consumption) fell considerably. (ppt-health.com)
They also regulate intracellular calcium homeostasis, serve as oxygen-sensors, regulate inflammation, participate in cellular and organellar quality control and regulate the cell cycle. (bvsalud.org)
That oxygen is essential for cellular respiration and metabolism has long been known. (unav.edu)
When certain pathological conditions lead to a decrease in the oxygen needed by tissues, known as hypoxia, cellular sensors trigger an alarm system aimed at counteracting this effect. (unav.edu)
Therefore, this year's award Nobel Prize recognizes the effort of research that, being largely on basic cellular mechanisms, has had enormous relevance in the treatment of patients with various diseases, whose common basis is the alteration in the supply of oxygen to the cells. (unav.edu)
Other effects include impaired cellular respiration, altered cell signaling , apoptosis , and impaired calcium homeostasis . (bmglabtech.com)
Cell respiration was inhibited by AAP concentrations of 500 mg/l and more in all three cell types, whereas only the cellular acidification rates and cell adhesion of the rat hepatocytes and the HepG2 cells were affected by AAP. (altex.org)

This cutting-edge sleep tracker utilizes advanced sensor technology to record various vital signs during sleep, such as heart rate variability, respiration rate, and oxygen saturation levels. (aplagen.com)
With the appropriate algorithm, it can determine human heart rate, blood oxygen saturation (SpO2), respiration rate and heart rate variability. (renesas.com)

And by contributing, I mean how much oxygen they can produce via photosynthesis versus how much they can consume via respiration. (weebly.com)
In other words, what is going on during the day (photosynthesis) and what's going on at night (respiration). (weebly.com)

Permeabilization of cells which leaves the mitochondrial membrane intact allows the study of mitochondrial function without the need to isolate mitochondria. (cyprotex.com)
ROS may originate from mitochondria and/or NADPH oxidases but the exact oxygen sensing mechanisms, as well as the question of whether increased or decreased ROS cause HPV, are under debate. (ersjournals.com)
Remember, the mitochondria are the energy furnaces of your cells. (ppt-health.com)
Cancer cells have damaged mitochondria. (ppt-health.com)
Other research shows that if you can restore the mitochondria of cancer cells, they can signal the cell to commit apoptosis. (ppt-health.com)
Physiological fission in healthy, nonproliferating cells mediates organellar quality control, eliminating dysfunctional portions of the mitochondria via mitophagy. (bvsalud.org)
In dividing cells, Drp1-mediated mitotic fission is critical to cell cycle progression, ensuring that daughter cells receive equitable distribution of mitochondria. (bvsalud.org)
Doerrier C, Garcia-Souza LF, Krumschnabel G, Wohlfarter Y, Mészáros AT, Gnaiger E (2018) High-Resolution FluoRespirometry and OXPHOS protocols for human cells, permeabilized fibres from small biopsies of muscle, and isolated mitochondria. (bioblast.at)
Living cells, permeabilized cells and tissue, or isolated mitochondria? (bioblast.at)
Makrecka-Kuka M, Krumschnabel G, Gnaiger E (2015) High-resolution respirometry for simultaneous measurement of oxygen and hydrogen peroxide fluxes in permeabilized cells, tissue homogenate and isolated mitochondria. (bioblast.at)

Calibration of polarographic oxygen sensors and oxygen concentration in respiration media at air saturation. (bioblast.at)
Oxygen is measured 3 ways, as partial pressure of oxygen (PaO2), as oxygen saturation (O2 Sat) and for oxygen content (O2CT) in the blood. (co2meter.com)

Apoptosis is programmed cell death for wayward cells. (ppt-health.com)
The latter is particularly found in the clinically high-risk subsets of 11q23/ATM or 17p/TP53 deleted/mutated CLL [5 6 A key to overcome such high thresholds for classical apoptosis would be to exploit impartial forms of (programmed) cell death. (tech-strategy.org)

Understand the mechanism of mitochondrial toxicity using Cyprotex's mitochondrial respiratory complex assay using permeabilized cells (Seahorse XF e 96). (cyprotex.com)
Cyprotex's mitochondrial respiratory complex assay utilising permeabilised cells on the Seahorse XF e analyzer is in Cyprotex's portfolio of in vitro toxicology services for measuring potential mitochondrial toxicity. (cyprotex.com)
Deficiency in ClpP induces an overload of mitochondrial misfolded/unfolded proteins, suppresses mitochondrial respiratory activity, increases mitochondrial oxidative damage and causes cell death. (springer.com)
Determination of respiratory activity is often performed for water organisms such as invertebrates, larval stages or eggs, but also for bacteria, cell cultures, yeasts or fungi. (presens.de)

Observed changes in oxygen content were normalized to unamended controls to correct for oxygen loss from background respiration processes and variability due to temperature changes. (bco-dmo.org)
Study the effect of temperature on cell respiration. (vernier.com)
Ventilators may deliver a high-oxygen mixture at a carefully managed pressure, breath volume, respiration rate, humidity level and temperature. (med-technews.com)
The HS3003 is a highly accurate, fully-calibrated relative humidity and temperature sensor with fast measurement response time, allowing users to monitor the environment. (renesas.com)
1.25% RD. ESRF-ESF gas flow sensors provide calibrated and temperature compensated output on an SPI, I 2 C bus or analog output making them plug & play for direct interfacing to low voltage MCUs and systems. (a2zinc.net)
Field observations of the diurnal behavior of several parameters (oxygen concentration, chlorophyll fluorescence, photosynthetically active radiation (PAR), wind speed, temperature, suspended matter concentration, and zooplankton abundance) were conducted at three sites in the marine hypersaline lake Moynaki (Crimea). (mdpi.com)

The cutting edge Agilent Seahorse XFe24 is capable of analyzing mitochondrial respiration and glycolysis in live cells. (lsuhs.edu)

The most common application is to measure the exhaust-gas concentration of oxygen for internal combustion engines in automobiles and other vehicles in order to calculate and, if required, dynamically adjust the air-fuel ratio so that catalytic converters can work optimally, and also determine whether the converter is performing properly or not. (wikipedia.org)
Oxygen sensors are also used in hypoxic air fire prevention systems to continuously monitor the oxygen concentration inside the protected volumes. (wikipedia.org)
The sensor does not actually measure oxygen concentration, but rather the difference between the amount of oxygen in the exhaust gas and the amount of oxygen in the air. (wikipedia.org)
Information on oxygen concentration is sent to the engine management computer or engine control unit (ECU), which adjusts the amount of fuel injected into the engine to compensate for excess air or excess fuel. (wikipedia.org)
Oxygen concentration was monitored approximately every 8 hours with a fiber optic oxygen meter (Pyroscience, Aachen, Germany). (bco-dmo.org)
Gas with a defined oxygen concentration moves under positive pressure to the lungs, passing through bronchial tubes into tiny individual air sacs (alveoli). (med-technews.com)
The oxygen concentration varied over a wide range from 3.2 to 9.3 mg L −1 , demonstrating a clear diurnal rhythm. (mdpi.com)

Using the CO 2 Gas Sensor, you will monitor the carbon dioxide produced by peas during cell respiration. (vernier.com)
Following intubation - the insertion of an endotracheal tube into a patient's trachea - ventilators offer multiple modes for safely providing the lungs with sufficient oxygen and removing carbon dioxide. (med-technews.com)
We take food and oxygen and combine them together and make energy and carbon dioxide, and that's what microbes do, as well. (whoi.edu)
Armed with uninterrupted streams of heart rate readings, respiration rates and other health indicators, as well as personalized exposure data for environmental pollutants such as ozone and carbon monoxide, sick people could better manage chronic diseases, and healthy people could make even better decisions to keep themselves fit. (nanowerk.com)
Human life relies on respiration: the intake of oxygen and the release of carbon dioxide. (co2meter.com)
In order to measure respiration, physicians and health care workers use several oxygen and carbon dioxide gas sensors. (co2meter.com)
Exhaled breath still contains 13% to 16% oxygen, with the difference made up of an increase in water vapor and carbon dioxide. (co2meter.com)
To measure CO2 levels in expelled air, a capnograph relies on fast carbon dioxide sensors that can measure minute CO2 changes in real time. (co2meter.com)
This device contains sensors that give a readout of the levels of oxygen, carbon dioxide and the pH (alkalinity or acidity) measured in the blood sample. (co2meter.com)
Sensors in the climate chamber measure the levels of oxygen, carbon dioxide, heat and humidity. (lu.se)

In a project funded by the Baden-Württemberg Landesstiftung foundation, researchers at the University of Freiburg's Department of Microsystems Engineering (IMTEK) have now succeeded in developing a novel organ-on-chip model that allows the metabolic activity of cells to be monitored locally and in real time. (gesundheitsindustrie-bw.de)
The non-invasive oxygen sensors in shake flasks now ensure oxygen supply and give new insights into metabolic activity. (presens.de)

Fusion also favors oxidative metabolism, intracellular calcium homeostasis and inhibits cell proliferation. (bvsalud.org)
Several unexpected findings in genetically altered mice have prompted research into the direction of intermediate metabolism of skeletal cells. (mdpi.com)
We compared the response of primary human hepatocytes from two donors with primary rat hepatocytes and the cell line HepG2 to the test compound acetaminophen (AAP) by measuring oxygen consumption, extracellular acidification and cell adhesion as dynamic parameters of cell metabolism. (altex.org)

With the world-wide successful Oroboros O2k instrument, scientists measure oxygen consumption or cell respiration. (mitophysiology.org)

Store-operated Ca 2+ entry mediated by STIM1-gated Orai1 channels is essential to activate immune cells and its inhibition or gain-of-function can lead to immune dysfunction and other pathologies. (nature.com)

Pretreatment of the Ca 2+ selective Orai1 with the oxidant H 2 O 2 reduces I CRAC with C195, distant to the pore, being its major redox sensor. (nature.com)
The protein HMGB1 behaves as a redox sensor and its structural changes, which are conditioned by the oxidative environment, are associated with different functions of the protein. (hindawi.com)
HMGB1 is an abundant protein, 10 6 molecules per cell [ 7 ], which has been postulated as a redox sensor [ 8 ]. (hindawi.com)

granule) are small structures within cells, which function in cell respiration as powerhouses or batteries. (mitophysiology.org)
These powerhouses of the cell generate most of the energy needed to drive essential biological reactions and processes. (bmglabtech.com)

Two hypoxia sensor genes and their association with symptoms of acute mountain sickness in Sherpas. (cdc.gov)

The Seahorse XF e 96 extracellular flux analyzer is used to detect, in real time, effects of compounds on oxygen consumption rate (OCR) in order to assess mitochondrial function. (cyprotex.com)
While still in the research phase, the study of volatile organic compounds through the use of VOC sensors is a promising new field of medicine. (co2meter.com)

Changes in the redox state of cells affect proteins, lipids, and nucleic acids in different ways. (hindawi.com)
The plaques contain lipids, inflammatory cells, smooth muscle. (msdmanuals.com)

At the termination of each respiration experiment, samples were harvested and the microbial community was captured on a 0.22-micrometer (μm) polyethersulfone filter. (bco-dmo.org)
He initially planned to look for microbial respiration in the oil slick on the surface of the Gulf, but soon realized the cruise gave him the opportunity to expand his project. (whoi.edu)

Gnaiger E (2008) Polarographic oxygen sensors, the oxygraph and high-resolution respirometry to assess mitochondrial function. (bioblast.at)

Scientists use oxygen sensors to measure respiration or production of oxygen and use a different approach. (wikipedia.org)
Divers use oxygen sensors (and often call them ppO2 sensors) to measure the partial pressure of oxygen in their breathing gas. (wikipedia.org)
Since oxygen sensors are located in the exhaust stream, they do not directly measure the air or the fuel entering the engine, but when information from oxygen sensors is coupled with information from other sources, it can be used to indirectly determine the air-fuel ratio. (wikipedia.org)
The XF technology uses solid-state sensors to simultaneously measure both oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) in every well. (lsuhs.edu)
These oxygen sensors measure the partial pressure of both dissolved and gasseous oxygen. (presens.de)
we expose algae to different light levels, from total darkness to full irradiance, and measure the amount of dissolved oxygen either produced or consumed. (weebly.com)
I figured that the easiest way to figure out what microbes were doing was to measure the rate of their consumption of oxygen," explained Van Mooy, a marine chemist at Woods Hole Oceanographic Institution (WHOI). (whoi.edu)
To measure the change in oxygen during breathing oxygen sensors capable of taking a reading every second are used. (co2meter.com)
This type of sensor does not measure the CO2 level directly, instead it measured a change in pH from a reaction between CO2 and sodium bicarbonate which is proportional to the CO2 level. (co2meter.com)
Dr. Boudina also established a new assay to measure mitochondrial respiration using an oxygen sensor probe. (utah.edu)

With oxygen sensors the O2k addresses the question of rate: how fast does the engine run? (mitophysiology.org)
The oxygen consumption rate (OCR) of permeabilised HepG2 cells was measured in the presence of an appropriate complex I substrate (pyruvate). (cyprotex.com)
Cancer cells demand high energy production to sustain their pathological increase in proliferation rate. (hindawi.com)
VitalTag by Pacific Northwest National Laboratory is a chest-worn sticker that detects, monitors and transmits blood pressure, heart rate, respiration rate and other vital signs, eliminating the need for multiple medical devices. (applysci.com)
Because myocardial oxygen demand is determined mainly by heart rate, systolic wall tension, and contractility, narrowing of a coronary artery typically results in angina that occurs during exertion and is relieved by rest. (msdmanuals.com)

Oxygen sensor failure particularly affects the cardiovascular system, which supplies all body tissues, so a good understanding of the normal and pathological mechanism of the sensors is core topic to try to remedy it. (unav.edu)

Oxygen sensors are used in oxygen analyzers, which find extensive use in medical applications such as anesthesia monitors, respirators and oxygen concentrators. (wikipedia.org)

Komlódi T, Sobotka O, Gnaiger E (2021) Facts and artefacts on the oxygen dependence of hydrogen peroxide production using Amplex UltraRed. (bioblast.at)
Cardoso LHD, Doerrier C, Gnaiger E (2021) Magnesium Green for fluorometric measurement of ATP production does not interfere with mitochondrial respiration. (bioblast.at)
From the first discovery of piezoelectricity in wool and hair in 1941 to the Nobel Prize in Physiology or Medicine in 2021, which revealed that cells perceive pressure and trigger tactile sensation through the electromechanical coupling effect of proteins Piezo 1 and Piezo 2, piezoelectric biomaterials have always been mysterious and attractive to researchers. (springernature.com)

These currents are activated by interaction with ER-resident Ca 2+ sensor molecules STIM that translocate to plasma membrane-near regions in response to store depletion, inducing to store operated Ca 2+ entry (SOCE). (nature.com)
Cell respiration refers to the process of converting the chemical energy of organic molecules into a form immediately usable by organisms. (vernier.com)
Blood cells, molecules & diseases 2012 Aug 49 (2): 67-73. (cdc.gov)
Respiration provides a constant flow of oxygen molecules to our brain, organs and tissues while providing a way to remove the waste CO2 molecules that are created in the cells. (co2meter.com)

The process is well suited to flow-sensor assembly, since it virtually eliminates risk of heat, mechanical stress, or contamination to the sensor's fragile membrane. (med-technews.com)

The German innovator of a medically certified sensor for continuous and long-term heart rhythm monitoring. (mpo-mag.com)
For this reason, regardless of the procedure, wound, disease or illness, one of the first priorities of a physician is to insure continuous respiration. (co2meter.com)

Previous analyses of dopaminergic (DAergic) neurons from patients with Lewy-body pathology revealed a deficiency in nuclear-encoded genes for mitochondrial respiration, many of which are targets for the transcription factor estrogen-related receptor gamma ( Esrrg /ERRγ). (nature.com)
Laser-captured microdissected (LCM) DAergic neurons from postmortem tissue of patients with Lewy-pathology revealed a deficiency in expression for nuclear-encoded genes involved in mitochondrial respiration and function 12 . (nature.com)

Due to their rapid growth, many solid tumours have oxygen-deficient (hypoxic) areas that promote metastasis and reduce response to therapies. (gesundheitsindustrie-bw.de)
We can vary the oxygen content between air-like and highly hypoxic conditions,' Weltin points out. (gesundheitsindustrie-bw.de)

Additionally, cell respiration of germinating peas at two different temperatures will be tested. (vernier.com)
Additionally, piezoelectric potential in the lung generated during respiration could assist in binding oxygen to hemoglobin. (springernature.com)

The scientists stated that retinol acts like a "nutritional sensor. (ppt-health.com)
Collectively, both arms of this Module add scientific value to the work of vision scientists by reducing the time and effort required for basic cell culture assays such as viability and cell cycle assessments. (utsouthwestern.edu)

Komlodi T, Sobotka O, Krumschnabel G, Bezuidenhout N, Hiller E, Doerrier C, Gnaiger E (2018) Comparison of mitochondrial incubation media for measurement of respiration and hydrogen peroxide production. (bioblast.at)
2018. "A biomimetic multifunctional electronic hair sensor. (edu.au)

There is currently an enormous pharmacological arsenal capable of modulating oxygen supply, either by favoring normal growth in ischemic (poorly irrigated) tissues, or by inhibiting pathological growth. (unav.edu)
This was shown to be mediated by adipose tissue expansion promoting hypoxia of poorly vascularized tissues, which constitutes the driving force for the activation of nuclear factor-κB (NF-κB), a sensor of oxidative stress [24]. (encyclopedia.pub)
During night-time, water-column hypoxia can lead to anoxic conditions at the leaf/epiphyte interface, reducing diffusive O 2 supply and thus O 2 availability for plant respiration and transport to below-ground tissues. (frontiersin.org)

Didier Perret, medical business development manager, Branson Welding and Assembly at Emerson explains the role ultrasonically welded flow sensors played in Hamilton Medical's ventilators. (med-technews.com)
Fortunately, the company had already invested in years of design and development efforts in Switzerland, collaborating with Emerson and local machine builders to create and validate automated systems for assembling all-plastic flow sensors using Branson ultrasonic welding technology. (med-technews.com)
Due to the compact design, and versatility, ESRF-ESF gas flow sensors are ideal for medical, process & pharmaceutical equipment where high accuracy and reliability are of the essence. (a2zinc.net)

The discoveries of the award winners have enabled the development of new targeted drugs, either to enhance tissue vascularization when more oxygen is required, as in myocardial infarction, or to stop pathological vascularization, as in cancer or diabetic retinopathy. (unav.edu)

Orai1 proteins form the major ion conducting units mediating the Ca 2+ release activated Ca 2+ current (I CRAC ) in immune cells among many other cell types. (nature.com)
Cells that do not grow in assemblies in the organism, such as blood and immune cells, are grown floating in nutrient solutions as a so-called suspension culture. (gesundheitsindustrie-bw.de)
Metabolically active cells, neutrophils, and macrophages from the immune system produce high levels of ROS. (hindawi.com)
Consequently, the recruitment of immune cells during chronic inflammation increases oxidative stress (OS) in the microenvironment [ 2 ]. (hindawi.com)
It consists of 4 fluorescent channels (UV to far red) and has extensive applications including bright field cell counting, wound-healing and cell growth assays, cell line development, induced pluripotent stem cell (iPSC) reprogramming, 3D invasion and migration modeling, immune-oncology, virology, and fluorescent-based assays. (utsouthwestern.edu)

Commonly used radio- and chemotherapies are prooxidant strategies that alter cancer cells through ROS modulation and induce cell death [ 5 , 6 ]. (hindawi.com)

The sensor must be able to detect even tiny pressure changes that signal a patient's attempts to breathe naturally, adjusting to the patient's own inhalation process to comfortably support it with the required volume of oxygenated air. (med-technews.com)
The novelty of the discoveries of the researchers W.G. Kaelin, P.J. Ratcliffe and G.L. Semenza, recent winners of the award Nobel Prize in Medicine and Physiology, lies in the identification of sensors by which cells detect oxygen deficiency. (unav.edu)

Many studies implicate mitochondrial dysfunction as a key contributor to cell loss in Parkinson disease (PD). (nature.com)

The maintenance of the steady-state equilibrium between ROS generation and elimination is crucial for cell survival, while its loss causes cell death by different mechanisms triggered by oxidative damage. (hindawi.com)

Lentivirus (LV)-NRP-1 was transfected into rat primary cortical neuronal cultures before a 2-h oxygen-glucose deprivation and reoxygenation (OGD/R) injury to neurons. (biomedcentral.com)

Each incubation was monitored for oxygen content using remote optical oxygen sensors. (bco-dmo.org)

Van Mooy replicated the earlier study by making some of his measurements with an oxygen microelectrode, but he also used another, very different, method to determine oxygen levels. (whoi.edu)

This demand causes a voltage to build up, due to transportation of oxygen ions through the sensor layer. (wikipedia.org)

Representative data assessing the effects on Complex I, Complex II/III and Complex IV mitochondrial respiration on permeabilized HepG2 cells. (cyprotex.com)

The oxygen sensing and signal transduction machinery is located in the pulmonary arterial smooth muscle cells (PASMCs) of the pre-capillary vessels, albeit the physiological response may be modulated in vivo by the endothelium. (ersjournals.com)
It has whole-body (systemic) effects, particularly affecting those organ systems most sensitive to low oxygen levels: the central nervous system (brain), the cardiovascular system (heart and blood vessels), and the pulmonary system (lungs). (cdc.gov)
This article reviews assisted ventilation of the newborn, highlighting the concepts of pulmonary mechanics, gas exchange, respiration control, and lung injury that can be used to enhance conventional mechanical ventilation (CMV) so as to improve survival and reduce adverse effects. (medscape.com)

Symptoms of sickle cell disease can vary widely and may include fatigue, shortness of breath, delayed growth, frequent infections, and episodes of severe pain called "sickle cell crisis. (aplagen.com)
Measuring the gases in a patient's breath gives an indication of the effectiveness of the lungs to take in oxygen and expel CO2. (co2meter.com)
Because breath gas analysis is non-evasive, it can be done safely and provides instant feedback about the effectiveness of respiration. (co2meter.com)
While measuring CO2 and oxygen in the breath is instantaneous, arterial blood gas (ABGs) analysis give a more accurate view of the effectiveness of respiration. (co2meter.com)

The new Q-sensor thus adds diagnostic core information on pathologies, which will make the NextGen-O2k the leading technology for mitochondrial research and medicine. (mitophysiology.org)

Open circuit scuba divers test the gas before diving as the mixture remains unchanged during the dive and partial pressure changes due to pressure are simply predictable, while mixed gas rebreather divers must monitor the partial pressure of oxygen in the breathing loop throughout the dive, as it changes and must be controlled to stay within acceptable bounds. (wikipedia.org)

UW's Graham Nichol and Harborview Medical Center colleagues studying the reliability of a troponin-detecting, wrist-worn sensor in arriving cardiac arrest patients. (applysci.com)

With the help of the oxygen sensors, the researchers investigated the effect of the cancer drug doxorubicin using the stop/flow method as an example. (gesundheitsindustrie-bw.de)
The goal of the Cell Culture and Cell Phenotyping Module is to streamline cell culture and phenotyping analyses for vision researchers. (utsouthwestern.edu)
ASSIST researchers will use the tiniest of materials to develop self-powered health monitoring sensors and devices. (nanowerk.com)
There, ASSIST researchers will develop thermoelectric materials that harvest body heat and new nanosensors that gather health information from the body such as heart rates, oxygen levels and respiration data. (nanowerk.com)
The results of that work, coupled with low-power radios developed by the University of Michigan, will be used to process and transmit health data gathered by the sensors to computers and consumer devices, such as cell phones, so patients, doctors and researchers can easily digest it. (nanowerk.com)

An oxygen sensor will typically generate up to about 0.9 volts when the fuel mixture is rich and there is little unburned oxygen in the exhaust. (wikipedia.org)
they generate most of the cell's supply of adenosine triphosphate (ATP), the energy currency of the cell. (bmglabtech.com)

This Module component contains an Agilent Seahorse XFp live cell metabolic analyzer. (utsouthwestern.edu)
Each of these measurements are derived from the PaO2 measured via a Clark electrode type of oxygen sensor in the blood gas analyzer. (co2meter.com)

Next, cells were treated with protein kinase R inhibitor 2-aminopurine and mitochondrial division inhibitor 1 to examine changes in progesterone levels and expression levels of proteins and mRNAs involved in progesterone biosynthesis. (bvsalud.org)

While the dissolved oxygen sensors left inside the chambers gives us an understanding of what the community of algae is doing over a 24-hour cycle, Genoa also needs to know what the individual species are contributing. (weebly.com)

An oxygen sensor (or lambda sensor, where lambda refers to air-fuel equivalence ratio, usually denoted by λ) or probe or sond, is an electronic device that measures the proportion of oxygen (O2) in the gas or liquid being analysed. (wikipedia.org)

In conventional two-dimensional (2D) systems, these cells are cultured in nutrient medium on a glass or plastic support and form a single-cell layer known as a monolayer. (gesundheitsindustrie-bw.de)
However, the measurement of metabolic parameters has so far mainly been carried out using fluorescence staining and the removal of nutrient medium or cell material. (gesundheitsindustrie-bw.de)

Anatomy3

Organisms1

Diseases2

Chemicals and Drugs19

Analytical, Diagnostic and Therapeutic Techniques and Equipment8

Phenomena and Processes17

Technology, Industry, Agriculture1

Information Science4

Reactive14

Aerobic5

Cellular9

Heart rate variab2

Photosynthesis2

Mitochondria10

Saturation2

Apoptosis2

Respiratory4

Temperature6

Glycolysis1

Concentration7

Carbon10

Metabolic activity2

Metabolism3

Oroboros O2k1

Inhibition1

Redox sensor3

Powerhouses2

Hypoxia sensor1

Compounds2

Lipids2

Microbial2

Assess mitochondrial function1

Measure10

Rate5

Mechanism1

Concentrators1

20213

Molecules4

Membrane1

Continuous2

Genes2

Hypoxic2

Additionally2

Scientists2

20182

Tissues3

Flow sensors3

Pathological1

Immune5

Induce cell1

Detect2

Mitochondrial dysfunction1

Oxidative damage1

Glucose1

Incubation1

Determine1

Ions1

Complex IV1

Pulmonary3

Breath4

Pathologies1

Partial pressure of oxygen1

Cardiac1

Researchers5

Generate2

Analyzer2

Proteins1

Algae1

Refers1

Nutrient2