Cell AgingOxidative StressCyclin-Dependent Kinase Inhibitor p16Telomerebeta-GalactosidaseReactive Oxygen SpeciesAging, PrematureCyclin-Dependent Kinase Inhibitor p21AgingTelomeraseBiological ProcessesTumor Suppressor Protein p53Cells, CulturedAntioxidantsTelomere ShorteningDNA DamageHydrogen PeroxideApoptosisFibroblastsSignal TransductionCell ProliferationLipid PeroxidationEndothelial CellsCell Line, TumorSuperoxide DismutaseRetinoblastoma ProteinOxidantsGlutathioneMalondialdehydeCell CycleUp-RegulationGene Expression RegulationBlotting, WesternCatalaseBiological MarkersTime FactorsCell LineMice, Inbred C57BLTOR Serine-Threonine KinasesThiobarbituric Acid Reactive SubstancesRNA, Small InterferingRNA InterferenceDown-RegulationEndothelium, VascularOxidation-ReductionMice, KnockoutPhenotypeProtein Carbonylationp38 Mitogen-Activated Protein KinasesReverse Transcriptase Polymerase Chain ReactionPlant LeavesCell DivisionDose-Response Relationship, DrugGlutathione PeroxidaseStem CellsHistonesParaquatAtherosclerosisRNA, MessengerAcetylcysteineMitochondriaDNA-Binding ProteinsF2-IsoprostanesEnzyme ActivationPhosphorylationDeoxyguanosineCell Cycle ProteinsFlow Cytometrytert-ButylhydroperoxideTransfectionImmunohistochemistryCell DifferentiationAscorbic AcidGene Expression Regulation, NeoplasticAldehydesGlutathione DisulfideLongevityCell SurvivalNADPH OxidaseFree Radical ScavengersNF-E2-Related Factor 2SuperoxidesIsoprostanesDisease Models, AnimalRats, WistarCell DeathVitamin EMutationRats, Sprague-DawleyModels, BiologicalGene Expression Regulation, PlantPeroxiredoxinsHeme Oxygenase-1InflammationVitamin K 3ChlorophyllCyclic N-OxidesGlutathione ReductaseNitric OxideStress, Physiological