Cell AgingOxidative StressFibroblastsAging, PrematureCyclin-Dependent Kinase Inhibitor p16Cells, CulturedTumor Suppressor Protein p53Reactive Oxygen SpeciesHydrogen PeroxideCyclin-Dependent Kinase Inhibitor p21beta-GalactosidaseTelomereDNA DamageAntioxidantsTelomeraseOxidantsAgingCell ProliferationCell LineApoptosisSignal TransductionRetinoblastoma ProteinCell CycleCell Transformation, NeoplasticFibroblast Growth Factor 2Cell Line, TumorRNA, Small Interferingtert-ButylhydroperoxideTumor Suppressor Protein p14ARFCaveolin 1Cell DivisionGene Expression RegulationMeclizineSkinPhenotypeMice, KnockoutCell SurvivalDiploidyPlant LeavesBlotting, WesternAcetylcysteineRNA, MessengerUp-RegulationTumor Suppressor ProteinsDNA-Binding ProteinsDown-RegulationOncogene Protein p21(ras)Sirtuin 1Lipid PeroxidationProgeriaSuperoxide DismutaseEndothelial CellsCell Cycle ProteinsMutationCell ShapeFibroblast Growth Factorsras ProteinsReverse Transcriptase Polymerase Chain ReactionNuclear ProteinsRNA InterferenceTime FactorsNIH 3T3 CellsGlutathionep38 Mitogen-Activated Protein KinasesStress, PhysiologicalRadiation, IonizingModels, BiologicalMalondialdehydeGenes, rasMice, Inbred C57BLProtein-Serine-Threonine KinasesGene ExpressionPhosphorylationAtaxia Telangiectasia Mutated ProteinsCatalaseTranscription FactorsClusterinTransfectionCell NucleusCaveolaeOxidation-ReductionGene Knockdown TechniquesEnzyme ActivationRepressor ProteinsPolycomb Repressive Complex 1Receptors, Fibroblast Growth FactorGamma RaysUltraviolet RaysThiobarbituric Acid Reactive SubstancesAutophagyAcetylationRoot Nodules, PlantPromoter Regions, GeneticLongevityMitochondriaProtein CarbonylationTelomere ShorteningNeoplasmsFibroblast Growth Factor 1Radiation Tolerance