Oxidative StressApoptosisReactive Oxygen SpeciesAntioxidantsCaspasesCaspase 3Apoptosis Regulatory ProteinsHydrogen PeroxideProto-Oncogene Proteins c-bcl-2Inhibitor of Apoptosis ProteinsMitochondriaCell SurvivalLipid PeroxidationGlutathioneDNA FragmentationSuperoxide DismutaseIn Situ Nick-End LabelingOxidantsCell Line, TumorSignal Transductionbcl-2-Associated X ProteinCells, CulturedMalondialdehydeX-Linked Inhibitor of Apoptosis ProteinCatalaseApoptosis Inducing FactorEnzyme ActivationBlotting, WesternCaspase 9Caspase InhibitorsCASP8 and FADD-Like Apoptosis Regulating ProteinThiobarbituric Acid Reactive SubstancesCell LineOxidation-ReductionTumor Suppressor Protein p53Cytochromes cProtein CarbonylationCaspase 8Tumor Cells, CulturedAcetylcysteineGlutathione PeroxidaseFas Ligand ProteinCell DeathDNA DamageCell ProliferationMembrane Potential, MitochondrialDose-Response Relationship, Drugbcl-X ProteinEnzyme InhibitorsMice, Inbred C57BLAnnexin A5Time FactorsParaquatFlow CytometryRNA, MessengerPoly(ADP-ribose) PolymerasesCysteine Proteinase InhibitorsDeoxyguanosineF2-IsoprostanesRats, Sprague-DawleyUp-RegulationDisease Models, AnimalAmino Acid Chloromethyl Ketonestert-ButylhydroperoxideCell CycleRNA, Small InterferingMice, KnockoutAldehydesPhosphorylationRats, WistarProto-Oncogene ProteinsAntineoplastic AgentsReverse Transcriptase Polymerase Chain ReactionFree Radical ScavengersTransfectionDown-RegulationNF-kappa BGlutathione DisulfideGene Expression RegulationTumor Necrosis Factor-alphaSuperoxidesNADPH OxidaseCytoprotectionNF-E2-Related Factor 2Ascorbic AcidCell DivisionNecrosisBiological MarkersJurkat CellsHL-60 CellsImmunohistochemistryModels, BiologicalProto-Oncogene Proteins c-aktCaspase 7TNF-Related Apoptosis-Inducing LigandGene ExpressionIsoprostanesNitric OxideMutationHeme Oxygenase-1