• The previous ozone (03) criteria document, Air Quality Criteria for Ozone and Other Photochemical Oxidants, was released in August 1986 and a supplement, Summary of Selected New Information on Effects of Ozone on Health and Vegetation, was released in January 1992. (epa.gov)
  • The purpose of this revised air quality criteria document for 03 and related photochemical oxidants is to critically evaluate and assess the latest scientific data associated with exposure to the concentrations of these pollutants found in ambient air. (epa.gov)
  • Volume 1 of 3 of the publication: Air Quality Criteria for Ozone and Related Photochemical Oxidants [includes Executive Summary]. (epa.gov)
  • however, other scientific data are presented and evaluated in order to provide a better understanding of the nature, sources, distribution, measurement, and concentrations of 03 and related photochemical oxidants and their precursors in the environment. (epa.gov)
  • Recent research demonstrates that redox dysregulation originating from metabolic alterations and dependence on mitogenic and survival signaling through reactive oxygen species represents a specific vulnerability of malignant cells that can be selectively targeted by pro-oxidant non-genotoxic redox chemotherapeutics. (wikipedia.org)
  • and (3) to characterize and quantify the cigarette smoke-induced "redoxome" of redox-prone metabolites in lung and serum that could be affected by the oxidants in cigarette smoke, and to assess its role in ciliopathy. (fda.gov)
  • Oxidant Physiology is an interdisciplinary section encompassing free radical biology, redox signaling, pathogenic mechanisms of oxidant injury and molecular control of oxidant stress as it relates to cellular, organ and systems physiology. (frontiersin.org)
  • During evolution, specific strategies have been developed by mammalian cells to manage pro-oxidant conditions, maintain redox balance and utilize these agents for the regulation of biochemical pathways. (frontiersin.org)
  • Here we review the evidence that both supports and conflicts with the free radical theory and examine the growing link between mitochondrial metabolism, oxidant formation, and the biology of aging. (nih.gov)
  • Therefore, comprehensive knowledge of the underlying mechanisms of oxidant and free radical production and the defence against this permanent threat to cells is important for the understanding of many physiological and pathophysiological processes. (springer.com)
  • With the current knowledge that oxidants are generated in inflammatory responses of several kinds and participate in the development of tissue injury, it is clearly important to gain greater insight into the mechanisms by which oxidants damage cells and extracellular tissues. (springer.com)
  • For the past few years we have studied the effects on target cells of oxidants that are generated by stimulated leukocytes,in order to gain insight into the mechanisms by which externally generated oxidants cause functional and structural damage to these target cells. (springer.com)
  • The chemical enigma that is both a pollutant and an antipollutant and environmental science's newest cause célèbre oxidants Responsible for chemical reactions both harmful and benign, oxidants represent the sort of chemical puzzle that have scientists both concerned and fascinated. (researchandmarkets.com)
  • It was once thought that anti-oxidants played a role in the increased longevity in many species of animals caused by calorie restriction. (rationalwiki.org)
  • The authors conclude that crystalline silica is a direct stimulant of oxygen metabolism and release of reactive oxidant species by both alveolar macrophages and neutrophils in-vitro and that silica can induce the release of mediators which are chemoattractants and activators of neutrophils. (cdc.gov)
  • Many health claims related to anti-oxidants rely on the free-radical theory of cell degeneration, which has also been debunked by the FDA . (rationalwiki.org)
  • Each formula is consciously made free of notoriously B.A.D. ingredients and driven by a proprietary PATENTED ANTI-POLLUTION BLEND of six powerhouse anti-oxidants building the foundation for healthy, radiant skin. (sephora.com)
  • A mixed oxidant solution production system contains corrosion-resistant electrodes or dimensionally-stable anodes (DSA) and is made so that different voltages for electrolysis are applied simultaneously to different parts. (wikipedia.org)
  • For example, chronic manganism is a classic "pro-oxidant" disease. (wikipedia.org)
  • Another disease associated with the chronic presence of a pro-oxidant transition-series metal is hemochromatosis, associated with elevated iron levels. (wikipedia.org)
  • Glutathione cycle activity and pyridine nucleotide levels in oxidant-induced injury of cells. (springer.com)
  • Alterations in adenosine triphosphate and energy charge in cultured endothelial and P388D1 cells following oxidant injury. (springer.com)
  • Oxidant injury of cells: DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide. (springer.com)
  • The second and potentially groundbreaking finding in the study by Lob et al 3 is that the SFO, at least in part through SOD3, may couple central and peripheral oxidant systems through activation of peripheral T cells, thereby providing a possible common underlying mechanism of hypertension that spans multiple organ systems. (ahajournals.org)
  • The Biological Oxidant and Life Detection (BOLD) is a concept mission to Mars focused on searching for evidence or biosignatures of microscopic life on Mars. (wikipedia.org)
  • There is always some trendy fruit from some exotic locale that is jumped on by the health food industry as "a good source of anti-oxidants. (rationalwiki.org)
  • These are typically part of lotions, ointments and other goops applied to the skin, which suffer from "a paucity of controlled clinical trials in humans examining the role of anti-oxidants in preventing or decelerating skin aging. (rationalwiki.org)
  • Implicated in deadly smog episodes and arteriosclerosis, oxidants have also played a major role in treating polluted waters and in certain anticancer drugs. (researchandmarkets.com)
  • The study, published online ahead of print of the July 15 issue of the journal Cancer, found almost 70 percent of the women used high doses of anti-oxidants, defined as higher than the amount contained in a Centrum multivitamin. (redorbit.com)
  • The pro-oxidant herbicide paraquat, Wilson's disease, and striatal iron have similarly been linked to human Parkinsonism. (wikipedia.org)
  • B. Halliwell and J. M. C. Gutteridge, Iron as a biological pro-oxidant, ISI Atlas Sci. (springer.com)
  • The goal of this five-year investigation is to examine metabolomic changes in smoking-related airway ciliopathy in order to identify a link between smoking, burden of oxidants to the lung epithelium and COPD pathogenesis. (fda.gov)