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  • Mice
  • A lamellar body mimetic system for the treatment of oxazolone-induced atopic dermatitis in hairless mice. (readbyqxmd.com)
  • The oxazolone-induced atopic dermatitis in hairless mice was used to evaluate in vivo the effect of the application of a lipid system that mimics the morphology, structure and composition of epidermal lamellar bodies. (readbyqxmd.com)
  • Ear swelling, epidermis thickening, and eosinophils infiltration in the oxazolone-mediated dermatitis of BALB/c mice were significantly reduced upon topical application of J. chinensis fruits 95% EtOH extract (JCE). (readbyqxmd.com)
  • Abrogation of the gene's activity generally increases type 2 cytokines and may make mice more vulnerable to oxazolone-induced colitis. (wikipedia.org)
  • peptide
  • The diketopiperazine b 2 + ion is thermodynamically more stable than the oxazolone but normally requires a trans/cis peptide bond isomerization in the dissociating peptide. (springer.com)
  • In the present case, solution-phase NMR spectroscopy and gas-phase IRMPD action spectroscopy show that the PPG precursor ion has its first amide bond in a trans configuration suggesting that the third residue is playing an important role in both the structure of the peptide and the associated ring-closure barriers for oxazolone and diketopiperazine formation. (springer.com)
  • Recently, it has been suggested that mb OB3b is derived from a small, ribsomally-produced peptide precursor with the sequence of L-C-G-S-C-Y-P-C-S-C-M. Functional mbOB3b is composed of (isobutyl group)-(Oxazolone ring A)-G-S-C-Y-(Oxazolone ring B)-S-M. (Note that some specimens of mBOB3b are found without the C-terminal methionine and appear fully functional. (wikipedia.org)
  • model
  • To examine the effects of IL-4DM in vivo in an AD model induced by the repeated exhibition of oxazolone (OX). (europills365.com)
  • Oxazolone induced-allergic contact dermatitis is a preclinical model routinely used at NEUROFIT for identifying potential anti-inflammatory and immuno-modulating drugs. (neurofit.com)
  • sodium
  • Historically, most animal models of IBD have been chemically induced using agents such as dextran sulfate sodium (DSS), 2,4,6-Trinitrobenzenesulfonic acid ( TNBS ) or oxazolone. (bolderbiopath.com)
  • mouse
  • Homann J, Suo J, Schmidt M, de Bruin N, Scholich K, Geisslinger G, Ferreirós N (2015) In Vivo Availability of Pro-Resolving Lipid Mediators in Oxazolone Induced Dermal Inflammation in the Mouse. (fraunhofer.de)