As an adjuvant to therapy with penicillin or with ampicillin, methicillin, oxacillin, cloxacillin, or nafcillin, for elevation and prolongation of plasma levels by whatever route the antibiotic is given. (nih.gov)
Methicillin6
However, with the introduction and widespread use of both oxacillin and methicillin, antibiotic-resistant strains called methicillin-resistant and oxacillin-resistant Staphylococcus aureus (MRSA/ORSA) have become increasingly prevalent worldwide. (wikipedia.org)
Oxacillin, a derivative of methicillin, was first synthesized in the early 1960s as part of a research initiative led by Peter Doyle and John Naylor of Beecham, in consort with Bristol-Myers. (wikipedia.org)
While methicillin could only be administered via injection, the isoxazolyl penicillins, including oxacillin, could be given orally or by injection. (wikipedia.org)
Methicillin resistance was tested by using 1 μg oxacillin disks (Oxoid, Basingstoke, Hampshire, UK) on Mueller-Hinton agar containing 4% sodium chloride. (cdc.gov)
Objectives To study the prevalence of methicillin sodium-resistant and methicillin-sensitive Staphylococcus aureus colonization in a child care center following the diagnosis of community-acquired methicillin-resistant S aureus (MRSA) disease in a previously well 212-year-old attendee and to determine the optimal site of detection of S aureus . (jamanetwork.com)
In the presence of oxacillin, the integrity of the cell wall for methicillin-susceptible S. aureus (MSSA) was destroyed immediately and appeared Gram negative. (bvsalud.org)
The bactericidal activity of Oxacillin results from the inhibition of cell wall synthesis and is mediated through Oxacillin binding to penicillin binding proteins (PBPs). (ncats.io)
The subject merchandise, which you designate by the tradename "Bactocill", is an injectable medicament, put up in vials, containing sodium oxacillin (an antibiotic) as the active ingredient. (faqs.org)
Oxacillin (trade name Bactocill) is a narrow-spectrum beta-lactam antibiotic of the penicillin class developed by Beecham. (wikipedia.org)
Oxacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. (ncats.io)
Oxacillin , sold under the brand name Bactocill among others, is an antibiotic used to treat and prevent straphylococcal infections. (mdwiki.org)
Piperacillin / tazobactam are antibacterial combination for intravenous administration which consists of semi synthetic antibiotic piperacillin sodium and a ß-lactamase inhibitor tazobactam sodium. (cathaydrug.com)
Oxacillin sodium was marketed under the trade name Bactocill. (ncats.io)
Dicloxacillin2
Members of the isoxazolyl penicillin family, which includes cloxacillin, dicloxacillin, and oxacillin, were synthesized to counter the increasing prevalence of infections caused by penicillin-resistant Staphylococcus aureus. (wikipedia.org)
sodium bicarbonate will decrease the level or effect of atazanavir by increasing gastric pH. (medscape.com)
sodium bicarbonate decreases levels of demeclocycline by inhibition of GI absorption. (medscape.com)
sodium bicarbonate decreases levels of fleroxacin by inhibition of GI absorption. (medscape.com)
sodium bicarbonate will decrease the level or effect of itraconazole by increasing gastric pH. (medscape.com)
Cloxacillin1
Following the synthesis of cloxacillin and oxacillin, Beecham retained the right to commercially develop cloxacillin in the United Kingdom while Bristol-Myers was given the marketing rights for oxacillin in the United States. (wikipedia.org)
Injection2
As an injection, oxacillin may cause injection site reactions, which may be characterized by redness, swelling, and itching. (wikipedia.org)
Oxacillin sodium for injection for intramuscular or intravenous injection prescribing information. (wikipedia.org)
Penicillins1
By decreasing the integrity of the bacterial cell wall, it is thought that oxacillin and other penicillins kill actively growing bacteria through cell autolysis. (wikipedia.org)
Chloride1
It grows well in up to 10% sodium chloride, but no growth is seen over 15% concentration. (kenyon.edu)
Inhibitor2
it is possible that Oxacillin interferes with an autolysin inhibitor. (ncats.io)
Here, we describe a new simple, rapid identification method for MRSA using oxacillin sodium salt, a cell wall synthesis inhibitor, combined with Gram staining and machine vision (MV) analysis. (bvsalud.org)
Isolates1
High levels of resistance were however expressed by all isolates to penicillin, oxacillin and ampicillin. (e-fas.org)
Parenteral1
Piperacillin / tazobactam parenteral combination (VIGOCID), is a white powder consisting of piperacillin and tazobactam as their sodium salts. (cathaydrug.com)
Salts1
For example, oxacillin and ibufenac are INN and their salts are named oxacillin sodium and ibufenac sodium. (drugs.com)
Daptomycin1
We screened the Nebraska Transposon Mutant Library of 1920 single-gene inactivations in S. aureus strain JE2, for increased susceptibility to the anti-staphylococcal antimicrobials (ciprofloxacin, oxacillin, linezolid, fosfomycin, daptomycin, mupirocin, vancomycin, and gentamicin). (frontiersin.org)
MRSA2
IMPORTANCE Oxacillin sodium salt destroys the integrity of the cell wall of MSSA immediately, appearing Gram negative, whereas MRSA is relatively stable and still appears Gram positive. (bvsalud.org)
The results show that using oxacillin sodium salt combined with Gram staining and MV analysis is a new, simple and rapid method for identification of MRSA. (bvsalud.org)
Acid2
As with other members of the penicillin family, the chemical structure of oxacillin features a 6-aminopenicillanic acid nucleus with a substituent attached to the amino group. (wikipedia.org)
Probenecid has also been reported to inhibit the renal transport of many other compounds including aminohippuric acid (PAH), aminosalicylic acid (PAS), indomethacin, sodium iodomethamate and related iodinated organic acids, 17-ketosteroids, pantothenic acid, phenolsulfonphthalein (PSP), sulfonamides, and sulfonylureas. (nih.gov)
Drugs1
Common to all members of the penicillin class of drugs, oxacillin may cause acute or delayed hypersensitivity reactions. (wikipedia.org)
Resistance1
The substituent present on oxacillin is thought to impart resistance to degradation via bacterial β-lactamases. (wikipedia.org)
Oral1
According to a 10/12/16 FDA update, "Health care professionals may resume normal use of oral liquid docusate sodium not manufactured by PharmaTech. (cdc.gov)
Antibiotics1
citation needed] The use of oxacillin is contraindicated in individuals that have experienced a hypersensitivity reaction to any medication in the penicillin family of antibiotics. (wikipedia.org)
Salt1
Product name:Rifamycin sodium salt CAS:14897-39-3 Purity:98% Packing: can be according to customer specific requirement. (vvchem.com)
Chemical2
Chemical name: sodium (2S,5R,6R)-6-[(R)-2-(4-ethyl-2,3-dioxo-1-piperazine-carboxamido)-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate. (cathaydrug.com)
Chemical name: sodium (2S,3S,5R)-3-methyl-7oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclol[3.2.0]heptanes-2-carboxylate-4,4-dioxide. (cathaydrug.com)
Infections caused1
Oxacillin is indicated in the treatment of infections caused by penicillinase producing staphylococci which have demonstrated susceptibility to the drug. (ncats.io)
Reaction1
Cross-allergenicity has been documented in individuals taking oxacillin that experienced a previous hypersensitivity reaction when given cephalosporins and cephamycins. (wikipedia.org)
Brand1
In addition to the above recall of all liquid products manufactured by PharmaTech, both FDA and CDC continue to recommend that clinicians and patients not use any brand of liquid docusate sodium product as a stool softener or for any other medical purpose. (cdc.gov)
High2
High doses of oxacillin have been reported to cause renal, hepatic, and nervous system toxicity. (wikipedia.org)
Quick Details ProName: High quality Rifamycin_S_Sodium CasNo: 14897-39-3 Molecular Formula: C37H44NNaO12 Appearance: A violet-brown crystalline power Application: An Medicine intermediate of rifamycin. (vvchem.com)
Activity1
Oxacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. (ncats.io)