Overviews cell fusion. Medical search. Frequent questions

The report "Global Spine Market with Focus on Spinal Fusion: Industry Analysis & Outlook (2017-2021)" by Koncept Analytics provides an extensive research and detailed analysis of the present market along with future outlook. (medgadget.com)

Picture shows translocation, pore formation, receptor mediated endocytosis using clathrin coated vesicles and membrane fusion. (rkm.com.au)
4. ENVELOPED VIRUS - ENDOCYTOSIS & MEMBRANE FUSION: virus enters cell by receptor mediated endocytosis. (rkm.com.au)
5. ENVELOPED VIRUS - MEMBRANE FUSION: virus enters the cell when its outer membrane fuses with the plasma membrane at the cell surface. (rkm.com.au)
The S protein would be cleaved by the cellular serine proteases TMPRSS2 into S1 and S2 subunits, which are responsible for receptor recognition and membrane fusion [ 12 , 13 ]. (newvita.com)
Virus entry relied on vacuolar acidification, with an optimal pH for viral membrane fusion at pH 5.5. (bvsalud.org)
The optimal pH for viral membrane fusion was slightly below 6.0, and penetration was hampered when the potassium influx was abolished. (bvsalud.org)
This is followed by entry, involving membrane fusion or membrane deformation into an endocytic vesicle. (lu.se)

As per DelveInsight analysis, the head and neck squamous cell carcinoma market is expected to grow positively at a significant CAGR during the study period (2019-2032). (advfn.com)
Head and neck squamous cell carcinoma (HNSCC) is a type of cancer that originates in the squamous cells lining the mucous membranes of the head and neck region. (advfn.com)
The head and neck squamous cell carcinoma epidemiology section provides insights into the historical and current head and neck squamous cell carcinoma patient pool and forecasted trends for individual seven major countries. (advfn.com)

This article appeared in Shuxun Chen, Jinping Cheng, Chi-Wing Kong, Xiaolin Wang, Shuk Han Cheng, Ronald A. Li, and Dong Sun , "Laser-induced fusion of human embryonic stem cells with optical tweezers", Appl. (edu.hk)

Excretory stem cells give rise to squamous cell and mucoepidermoid carcinomas, while intercalated stem cells give rise to pleomorphic adenomas, oncocytomas, adenoid cystic carcinomas, adenocarcinomas, and acinic cell carcinomas. (medscape.com)
Squamous cell carcinomas arise from excretory duct cells, pleomorphic adenomas arise from the intercalated duct cells, oncocytomas arise from the striated duct cells, and acinic cell carcinomas arise from acinar cells. (medscape.com)
Carcinoma, squamous cell. (bvsalud.org)
According to the World Health Organization (WHO), it corresponds to the 5th most common neoplasia worldwide, being the Squamous Cell Carcinoma (SCC) the most common malignancy. (bvsalud.org)

We leverage two precision oncology programs to investigate rhabdomyosarcoma with FUS/EWSR1-TFCP2 fusions, an orphan malignancy without effective therapies. (lu.se)

The quartz cuvette flow cell is in true fixed alignment with the laser and is gel coupled to the collection optics. (bdbiosciences.com)

Once the fluorophore is coupled to the desired protein, the label fluorescesces permitting visualization in living or fixed cells. (neb.com)
This approach permits discrimination of different populations of a cell surface protein: those properly translocated to the plasma membrane from those retained in the secretory pathway or already internalized ( e.g. upon ligand binding). (neb.com)
Read about the NEB's set of protein tools for the specific labeling (SNAP-, CLIP-, ACP- and MCP-tags) of fusion proteins. (neb.com)
NAKED VIRUSES have an exposed protein capsid, whilst ENVELOPED VIRUSES are cloaked in cell membrane, added during budding from the host cell. (rkm.com.au)
Some viruses release their genetic material almost immediately (see entry 2) whereas others transport it to the cell nucleus still contained in a protein vehicle (see entry 5). (rkm.com.au)
3. Target-specific Primary Antibody는 Antibody와 Fusion Enzyme의 pAG Domain의 Protein-protein 상호작용을 통해 pAG-MNase 을 Chromatin에 위치하게 함. (seoulin.co.kr)
To facilitate this exchange, red cells consist essentially of gas-carrying soluble protein (hemoglobin) surrounded by a protective cell membrane. (ivis.org)
It is developed using Picasso platform which is a fusion protein technology platform that modulates the natural mechanism of action of a biologic and provides safety and tolerability advantages. (pharmaceutical-technology.com)
The primary surface protein of the viral particle, the E protein (50 kD), likely interacts with viral receptors and facilitates fusion of the virus-cell membrane. (doctor-dr.com)
Viral internalisation into the host cell via clathrin-mediated endocytosis or apoptotic mimicry is mediated by the viral envelope protein E's attachment to host receptors. (doctor-dr.com)
The virion becomes mature and fusion competent when the prM protein is cleaved in the Golgi. (doctor-dr.com)
Bone morphogenetic protein and retinoic acid synergistically specify female germ cell fate in mice, The EMBO Journal, 36, 3100-3119. (kyoto-u.ac.jp)
The MUNC18-1 protein is a key protein that helps organize the SNARE-complex which is responsible for mediating vesicle fusion with the cell membrane or other vesicles 2 . (clinchoice.com)
Virus infection is initiated by the interaction between S protein and host cell surface receptors. (newvita.com)
Among its multiple functions, this protein signals immature cells to become bone cells during embryonic development. (medlineplus.gov)
A mutation in a specific part of the FGFR2 gene overstimulates signaling by the FGFR2 protein, which promotes the premature fusion of skull bones and affects the development of bones in the feet. (medlineplus.gov)

Chen, EH 2008, ' Cell Fusion: Overviews and Methods - Preface ', Methods in molecular biology (Clifton, N.J.) , vol. 475. (johnshopkins.edu)
Chen, Elizabeth H. / Cell Fusion : Overviews and Methods - Preface . (johnshopkins.edu)
Improved understanding of spinal biomechanics, proliferation of sophisticated spinal instrumentation devices, advances in bone fusion techniques, refinement of anterior approaches to the spine, and development of microsurgical and minimally invasive methods have made it possible to stabilize every segment of the spine successfully, regardless of the offending pathology. (medscape.com)
First, rigorous randomized controlled trials are needed to better assess the efficacy of existing methods of fusion. (medscape.com)
Hybrid cell lines are also used to study cancer and map genes The three most common methods of fusing cells to make a hybrid line are via oncogenic viruses, polyethylene glycol, or electrofusion. (wikipedia.org)
In this blog we will first overview the model system Chlamydomonas reinhardtii and methods for transforming this single celled, flagellated alga. (btxonline.com)
This implies that bulk expression measurements are often misleading, thus necessitating methods for studying gene regulation in single cells. (nature.com)
Second, while methods such as flow cytometry, smFISH, and single-cell RNA-seq provide snapshots of gene expression distributions across single cells (see e.g. refs. (nature.com)
We have also established methods for the proliferation of PGCLCs and their differentiation to spermatogonial stem cells in vitro. (kyoto-u.ac.jp)
In 1911, Russell Hibbs and Fred Albee independently developed the concepts and methods for bony fusion of the spine to address the symptoms of Pott disease. (medscape.com)
Bioinformatic Methods and Bridging of Assay Results for Reliable Tumor Mutational Burden Assessment in Non-Small-Cell Lung Cancer. (cdc.gov)

It is a new biologic entity based on fusion of IL-2 and its receptors (IL-2 receptor alpha). (pharmaceutical-technology.com)
The C-terminal domain (CTD) of S1 specifically binds to host cell receptors angiotensin-converting enzyme 2 (ACE2) or CD147, which causes the conformational change of S2. (newvita.com)

The primary red cell metabolic pathway is anaerobic glycolysis. (ivis.org)
The glycolytic pathway allows the cell to produce energy to maintain membrane stability with minimal utilization of oxygen. (ivis.org)
We also found an IL-17A-dependent pathway for DC fusion, which was highly potentiated by IFN-gamma and led to giant cells expressing three major tissue-destructive enzymes: tartrate resistant acidic phosphatase and matrix metalloproteinases 9 and 12. (dtu.dk)
Binding of SARS-CoV-2 to the angiotensin‐converting enzyme 2 (ACE2) is a vital pathway for the virus entry into human cells, including those of the respiratory mucosa, esophageal epithelium as well as the absorptive enterocytes from ileum and colon. (irjournal.org)

Tumor hybrid cells: fusion of tumor cells with normal bodily cells. (wikipedia.org)
Vaccines using dendritic cells, tumor cells, and fusions of tumor cells and antigen-presenting cells have also shown some promise in research, but further study is needed to obtain better, sustained results. (nih.gov)
Its metastatic potential depends on the phenotype of the tumor cells, and it frequently disseminates before diagnosis. (medscape.com)
Tumor-induced glaucoma may be produced by obstruction of outflow pathways by pigment cells (pigment dispersion syndrome), melanin-laden macrophages (melanomalytic glaucoma), or tumor cells. (medscape.com)

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Thickening of the actin filaments at the cell edge provided the bending force to extrude the virus particles. (cdc.gov)

The first instance of intentionally generated hybrid cells was described in 1960 by Barski, Sorieul, and Cornefert in their paper "Production of cells of a 'hybrid' nature in cultures in vitro of 2 cellular strains in combination," originally published in French. (wikipedia.org)
The env gene maintained an ORF coding for a 538-amino acid polypeptide that has all the characteristic features of env proteins and mediates intercellular fusion in vitro [ 11 - 13 ]. (ecancer.org)
We have successfully generated primordial germ cell-like cells (PGCLC) in vitro from mouse ESCs and iPSCs. (kyoto-u.ac.jp)
Generation of human oogonia from induced pluripotent stem cells in vitro, Science, 362, 356-360. (kyoto-u.ac.jp)
In Vitro Derivation and Propagation of Spermatogonial Stem Cell Activity from Mouse Pluripotent Stem Cells, Cell Reports, 17, 2789-2804. (kyoto-u.ac.jp)
Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells, Cell Stem Cell, 17, 178-194. (kyoto-u.ac.jp)
Our research strategy widely relies of the use of artificial lipid bilayers to mimic in vitro the basic molecular architecture of the cell membrane. (lu.se)

After assembly, the virus progeny particles are transported in vesicles to the cell periphery for release. (cdc.gov)
Exosomes are extracellular vesicles with a lipid bilayer membrane that can be released by all types of cells, which contain a variety of proteins, lipids, and a variety of non-coding RNAs. (ijbs.com)
Exosomes are vesicles with a bilayer membrane structure formed by a series of regulatory processes, such as "endocytosis-fusion-exclusion" of most cells (including T cells, platelets, and cancer cells), with a diameter of about 50-150 nm [ 10 ]. (ijbs.com)

It should be noted that whereas the term fusion, as used in this article and in spine literature to refer to the concept of internal stabilization of the spine, generally refers to fusion with instrumentation (instrumented fusion), such stabilization has also, albeit with decreasing frequency, been accomplished by means of bone grafting alone. (medscape.com)
Different MAAs were inserted into hybrid MHC-I and MHC-II constructs, and mRNAs were transfected into murine bone marrow derived dendritic cells (BMDCs) by electroporation using the BTX ECM 830 generator. (btxonline.com)
Red blood cells (RBC) are produced in the bone marrow. (ivis.org)
Effete red cells are phagocytized and metabolized by the macrophages of spleen, bone marrow, and liver. (ivis.org)
Langerhans cell histiocytosis (LCH) is a rare disease of unknown etiology, lacking an animal model, that cumulates symptoms that are found separately in various IL-17A-related diseases, such as aggressive chronic granuloma formation, bone resorption and soft tissue lesions with occasional neurodegeneration(11,12). (dtu.dk)
In current practice, bone grafting and instrumentation are often used concurrently based on the expectation that internal fixation of spine enhances the success of bone fusion while a successful bone fusion eliminates the possibility of hardware failure by reducing the chronic biomechanical stresses on the hardware construct. (medscape.com)
Of note, the term "fusion" is used in this article and in spine literature to refer to the concept of internal stabilization of spine, generally accomplished by fusion with instrumentation (instrumented fusion), but also, albeit with decreasing frequency, accomplished by bone grafting alone. (medscape.com)
Recipients of grafts containing immune cells (particularly bone marrow, intestine, and liver) are at risk of graft-vs-host disease, in which the donor immune cells attack recipient tissue. (msdmanuals.com)

2. NAKED VIRUS - GENOME INJECTION: virus attaches to cell surface and releases its genome which penetrates the cytoplasm via a pore that has been created in the plasma membrane. (rkm.com.au)
The surface form of the cells at advanced infection displayed prolific pseudopodia that, in addition to the rest of the plasma membrane, were also active sites of virus release. (cdc.gov)
SARS-CoV grows well in Vero E6 cells ( 1 , 2 , 10 ) and enters cells by direct fusion of the virus envelope with the plasma membrane ( 11 ). (cdc.gov)

Scanning electron and atomic force microscopy was used for the first time to view the maturation of the severe acute respiratory syndrome-associated coronavirus at the cell surface. (cdc.gov)
Coronavirus fusion with the cell membrane and internalization also depends on the interaction with the cellular serine protease transmembrane protease serine 2 (TMPRSS2), the cysteine proteases cathepsin B and L, furin and furin-like proteins [ 3 ]. (irjournal.org)

Fluorescence-Activated Cell Sorting (FACS) is a method for analysis and sorting of cells and other biological particles (e.g. exosomes) based on light scattering and fluorescence characterizations. (bgu.ac.il)
The Antibody Hybridoma Core offers hybridoma, clone and subclone supernate screening by enzyme-linked immunosorbent assay (ELISA), Western blot assay and fluorescence-activated cell sorting (FACS). (mayo.edu)
Since it is used for identifying cell-surface receptor molecules, FACS requires whole-cell suspensions and special cell-sorting equipment to process samples. (mayo.edu)

2. Primary Antibody와 pAG-MNase Fusion Enzyme이 핵으로 유입되는 것을 촉진시키기 위해 Digitonin으로 Cell Membrane Permeabilization. (seoulin.co.kr)
The His tag antibody is a useful tool for monitoring of the His-tagged proteins, and recognizes His-tags placed at N-terminal, C-terminal, and internal regions of fusion proteins expressed in bacteria, insect, and mammalian cells. (caslab.com)
The Antibody Hybridoma Core utilizes the fusion partner cell line FOX-NY, a nonimmunoglobulin-secreting myeloma cell line that is hypoxanthine-aminopterin-thymidine (HAT) sensitive. (mayo.edu)
Nine to 14 days after the fusion, hybrid supernatants are tested for the presence of the specific antibody of interest. (mayo.edu)

Experiments with cynomolgus monkey iPSC-derived PGCLCs have allowed us to analyze germ lineage development across different mammalian species and identify the early amniotic membrane as the origin of germ cells in primates. (kyoto-u.ac.jp)
How orthobunyaviruses (OBVs) penetrate and infect mammalian host cells remains poorly characterized. (bvsalud.org)

Epithelioid cells are associated with more aggressive behavior and carry a poorer prognosis for the patient's survival. (medscape.com)
Some of these mutations, such as (mixed-lineage leukemia) MLL fusions, are highly aggressive and can generate leukemia very quickly. (lu.se)

These are created as a byproduct of fertility testing, when human sperm potency is measured by how well it can penetrate a hamster egg cell (hamster eggs tend to have similar penetrability to human sperm as do human eggs). (wikipedia.org)
The aim of our research is elucidate the mechanisms by which viral pathogens interact with the cell'membrane to crosses it and penetrate into the cell. (lu.se)

SNAP-tag, CLIP-tag™ and cell surface-specific ACP/MCP-tag systems can specifically label subpopulations of target proteins expressed on the cell surface using non-cell permeable substrates (3). (neb.com)

Hybridoma: a fusion of B-cells and immortal cancer cells with the purpose of generating antibodies. (wikipedia.org)
Briefly, cells that are pre-labeled with fluorescence dye, antibodies conjugated to fluorophores, or expressing fluorescence proteins, are loaded into a stream. (bgu.ac.il)
Studying viral fusion proteins can allow us to better understand how they shape immune responses and inform the design of therapeutics such as drugs, monoclonal antibodies, and vaccines. (caltech.edu)
It discusses the architecture of these viruses and fusion proteins and how small molecules, peptides, and antibodies can target these proteins successfully to treat and prevent disease. (caltech.edu)

The BD FACSAria™ Fusion Flow Cytometer combines sorting capabilities with best-in-class biosafety expertise for a comprehensive advanced cell sorter and biosafety solution. (bdbiosciences.com)
The fluidics system in the BD FACSAria™ III cell sorter is pressure driven. (bgu.ac.il)

Polyethylene glycol functions by changing the direction and configuration of lipid molecules in the cell membrane, which increases their permeability and allows two membranes to fuse. (wikipedia.org)
3. NAKED VIRUS - ENDOCYTOSIS: virus attaches to cell surface receptor molecules and sinks into a clathrin coated pit. (rkm.com.au)

The software is common across many BD cell analyzers and cell sorters, making the BD FACSAria™ Fusion Flow Cytometer compatible with them. (bdbiosciences.com)
Get more information from the BD FACSAria™ Fusion Flow Cytometer brochure . (bdbiosciences.com)
The BD FACSAria™ Fusion Flow Cytometer can be purchased with or without a BSC. (bdbiosciences.com)
For greater sensitivity, the BD FACSAria III incorporates a next-generation cuvette in the flow cell. (bgu.ac.il)
In addition to other benefits, the next generation flow cell in the BD FACSAria III is designed to improve resolution for side population applications and DNA cell cycle analyses. (bgu.ac.il)

In cancers, tumor cell-derived exosomal circRNAs can act on target cells or organs through the transport of exosomes, and then participate in the regulation of tumor development and metastasis. (ijbs.com)
However, disease transmission and, the viral target cells and organs are still under investigation. (irjournal.org)

In response to vascular injury, circulating platelets adhere, aggregate, and provide cell surface phospholipids for the assembly of blood clotting enzyme complexes, thrombin activation, and fibrin formation. (medscape.com)

Transfected BMDCs were injected into mice bearing melanoma tumors to assess the anti-tumor activity and T-cell activation stimulated by these modified DCs. (btxonline.com)
This theory holds that tumors arise from 1 of 2 undifferentiated stem cells: the excretory duct reserve cell or the intercalated duct reserve cell. (medscape.com)
Unlike other fusion-driven sarcomas, TFCP2-rearranged tumors exhibit genomic instability and signs of defective homologous recombination. (lu.se)

The patient-derived Ph-like ALL RANBP2-ABL1 fusion gene was transduced into Ba/F3 cells and allowed to become resistant to the tyrosine kinase inhibitors (TKIs) imatinib or dasatinib, followed by secondary resistance to ponatinib. (sahmri.org.au)
Here we analyzed the genome-wide changes in gene transcription occurring during growth and differentiation of porcine primary myoblast cells. (au.dk)
Much is still not understood about how gene regulatory interactions control cell fate decisions in single cells, in part due to the difficulty of directly observing gene regulatory processes in vivo. (nature.com)
We introduce here a novel integrated setup consisting of a microfluidic chip and accompanying analysis software that enable long-term quantitative tracking of growth and gene expression in single cells. (nature.com)
The dual-input Mother Machine (DIMM) chip enables controlled and continuous variation of external conditions, allowing direct observation of gene regulatory responses to changing conditions in single cells. (nature.com)
Gene regulation is one of the key processes that underlie the complex behavior of biological systems, allowing cells to adapt to varying environments, and allowing multi-cellular organisms to express a large number of phenotypically distinct cell types from a single genotype. (nature.com)
In spite of more than half a century of intense study since the discovery of the basic mechanism of gene regulation 1 , much remains to be understood about the ways in which gene regulatory interactions control cell fate decisions. (nature.com)
The most common approach in such studies is to grow cells on a surface while tracking gene expression and growth using quantitative fluorescence time-lapse microscopy (QFTM). (nature.com)
which means one copy of the altered gene in each cell is sufficient to cause the disorder. (medlineplus.gov)
Development and Clinical Validation of a Large Fusion Gene Panel for Pediatric Cancers. (cdc.gov)
First, we looked at LIN28B, a gene recognized as the master regulator of fetal blood cell formation. (lu.se)

However, early virus-host cell interactions and entry mechanisms remain poorly characterized. (bvsalud.org)
The journey within this project promises to unravel a profound understanding of light-matter interactions within Zn 3 P 2 nanostructures, unlocking the potential for high-performance solar cells. (lu.se)

4 cm tumor size) or II non-small cell lung cancer [NSCLC]) and may provide the best possibility for a cure. (medscape.com)

Cell populations can also be sorted and collected into separate tubes. (bgu.ac.il)

Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells, Cell Stem Cell, 21, 517-532. (kyoto-u.ac.jp)
Hematopoietic Stem Cell Transplantation Hematopoietic stem cell (HSC) transplantation is a rapidly evolving technique that offers a potential cure for hematologic cancers ( leukemias, lymphomas, myeloma) and other hematologic disorders. (msdmanuals.com)
Living donors are often used for kidney and hematopoietic stem cell transplants, less frequently for segmental liver transplants, and rarely for pancreas and lung transplants. (msdmanuals.com)
Two theories predominate: the bicellular stem cell theory and the multicellular theory. (medscape.com)
Recent evidence suggests that the bicellular stem cell theory is the more probable etiology of salivary gland neoplasms. (medscape.com)

In this setting, clinical practice is guided by an understanding of the principles of spinal biomechanics (see Pathophysiology ) and knowledge of the generally accepted indications, contraindications, and controversies regarding fusion surgery (see Treatment ). (medscape.com)

Three distinct cell types are recognized in uveal melanomas: spindle A, spindle B, and epithelioid. (medscape.com)

The cytoskeletal network along the edge of the infected cells was enhanced and could be involved in transporting and expelling the progeny virus particles. (cdc.gov)
Strikingly, the particles remained infectious after entering late endosomes with a pH below the fusion threshold. (bvsalud.org)
Labeling of the virus with fluorescent dyes did not adversely affect its infectivity and allowed the monitoring of single particles in fixed and live cells. (bvsalud.org)

For example, immunoglobin-producing B lymphocytes can be fused with myeloma to produce an immortal line of cells called hybridoma that secrete immunoglobin. (wikipedia.org)
The fusion process involves fusing spleen or lymph node cells with a myeloma fusion partner cell line. (mayo.edu)

To increase the understanding of the intercellular dynamics of quiescent CD8+ T-cell interaction with DC and CD-4+ helper cells, Abu Shah, et. (btxonline.com)

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The results can assist in further understanding how SARS CoV interacts with infected cells at late infection. (cdc.gov)

Leukemia is characterized by the abnormal and uncontrolled expansion of malfunctioning blood cells that crowd out normal cells. (lu.se)

For successful infection of host cells and virion production, enveloped viruses, including Zika virus (ZIKV), extensively rely on cellular lipids. (bvsalud.org)

The viral contents are then spilled into the cytoplasm of the cell. (rkm.com.au)
The release of the virus' RNA genome into the cytoplasm is caused by the fusion of the host endosomal membrane with the viral membrane. (doctor-dr.com)

However, it soon became apparent that the application of spinal instrumentation (without fusion) for treatment of spinal instability often ended in breakage or loosening of the hardware (hardware failure). (medscape.com)

GFP) cannot specifically visualize cell surface subpopulations. (neb.com)
Utilizing electroporation to transfect mRNA constructs of modified antigen-specific TCRs, the researchers were able to express functional TCR on the surface of the quiescent T-cells and show activation by interaction with DCs loaded with the corresponding peptide antigen. (btxonline.com)
Graphic of Viral Entry into Animal Cells: virus attachment to cell surface (adsorption) and virus entry into cell. (rkm.com.au)
The aim of this study was to use scanning electron and atomic force microscopes to investigate changes in the surface topography of SARS-CoV-infected cells at late infection. (cdc.gov)
H. Zhang, M. Shimada, B. Pawelko, A. Ying, M. Abdou, S. Cho, " Characterization of Tritium Isotopic Permeation through ARAA in Diffusion Limited and Surface Limited Regime ", Fusion Science and Technology, 72:416-425 (Jun2017). (ucla.edu)
Investigating iPSC-derived human neurons and cell lines, we found that virus binding to the cell surface was specific, and 50% of bound virions were endocytosed within 10 min. (bvsalud.org)
We further, take advantage of total internal fluorescence microscopy and single particle tracking to study, on a single particle level, virus attachment to and diffusion on the cell surface. (lu.se)
Taken together, these examples illustrate the potential of artificial cell membrane mimics in the study of processes occurring at the surface of a cell and demonstrate how such biophysical data can complement more classical cell-biology experiments. (lu.se)

During myogenesis the satellite cells undergo a series of highly ordered events that include division and proliferation of mononucleated myoblasts, irreversible cell cycle withdrawal, elongation of myoblasts and finally cell-cell fusion, leading to the formation of multinucleated myotubes. (au.dk)

Overall, our study provides real-time visualization of GERV entry into host cells and demonstrates the importance of late endosomal maturation in facilitating OBV penetration. (bvsalud.org)

The project aims to systematically study how this interaction, ranging from weak to strong coupling regimes, modifies dynamic processes in various systems, such as photosynthetic units, solar cell films, and rare-earth ion-doped nanoparticles, with a combined setup of a tuneable microcavity system and ultrafast pump probe spectroscopy. (lu.se)

A great deal of controversy remains regarding the application of fusion surgery in the treatment of degenerative spine disease without overt instability. (medscape.com)
Spinal fusion segment has witnessed significant growth in the spine market because of increased cases of severe lumber and cervical disorders. (medgadget.com)
The U.S. is likely to experience further growth of spine market with technological advancements in surgical devices, growing cases of spinal diseases in older populace and rising adoption of spinal fusion. (medgadget.com)
Although this constituted a major advance in spine surgery that was subsequently applied to a much wider range of pathological disorders and which remains in use today, the method of onlay posterior grafting, when performed in isolation, suffered from an unacceptably high rate of pseudarthrosis (failed fusion). (medscape.com)

For instance, DTG decreases the renal clearance of metformin by inhibiting organic cation transporters in renal tubular cells. (medscape.com)

Certain oncogenic viruses encode for fusogens, which are proteins that encourage two cell membranes to fuse. (wikipedia.org)
When the viral genes are expressed by the host cell, the membranes of two cells may fuse. (wikipedia.org)
After the cells are aligned, a pulse voltage around 10V can be applied, causing the membranes of these cells to fuse. (wikipedia.org)
Fusion of host and viral membranes is critical for the lifecycle of enveloped viruses. (caltech.edu)

abstract = "IL-17A is a T cell-specific cytokine(1) that is involved in chronic inflammations, such as Mycobacterium infection(2), Crohn's disease(3), rheumatoid arthritis(4) and multiple sclerosis(5). (dtu.dk)

Strictly defined, spinal fusion is an operation designed to treat spinal instability. (medscape.com)
Spinal fusion and instrumentation were developed and applied as independent techniques for treatment of spinal instability in the first half of the 20th century, before the biomechanical principles surrounding spinal instability were understood. (medscape.com)

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