Mice, TransgenicProto-Oncogene Proteins c-bcl-2Gene ExpressionTransfectionCell Line, TumorApoptosisSignal TransductionRNA, MessengerMolecular Sequence DataTranscription FactorsCell LineGene Expression Regulation, NeoplasticDNA-Binding ProteinsUp-RegulationImmunohistochemistryGene Expression RegulationMutationBlotting, WesternReverse Transcriptase Polymerase Chain ReactionBase SequenceProto-Oncogene ProteinsPromoter Regions, GeneticRNA, Small InterferingCell ProliferationCells, CulturedAmino Acid SequenceDown-RegulationProtein BindingPhosphorylationNuclear ProteinsNeoplasm ProteinsRNA InterferencePhenotypeCarrier ProteinsMembrane ProteinsTumor Suppressor Protein p53Genes, bcl-2Transcription, GeneticRepressor ProteinsMice, Inbred C57BLTumor Cells, CulturedCell DifferentiationRecombinant Fusion ProteinsCell DivisionProtein-Serine-Threonine KinasesAdenoviridaeAdaptor Proteins, Signal TransducingCell SurvivalGene Knockdown TechniquesGene Expression Regulation, EnzymologicDNA PrimersRecombinant ProteinsCloning, MolecularGene Expression ProfilingGenetic VectorsBreast NeoplasmsCell CycleGene AmplificationTrans-ActivatorsEnzyme ActivationCyclin D1Cell Transformation, NeoplasticProtein Structure, TertiaryDNA, ComplementaryReceptor, erbB-2Intracellular Signaling Peptides and ProteinsHeLa CellsCell Cycle ProteinsNF-kappa BTranscriptional ActivationPlants, Genetically ModifiedCell NucleusProtein TransportMice, KnockoutCell MovementGene Expression Regulation, DevelopmentalHEK293 CellsTranslocation, GeneticMicroRNAsTime FactorsTumor Markers, BiologicalCaspasesSequence Homology, Amino AcidNeoplasm InvasivenessImmunoprecipitationPlasmidsLymphoma, B-CellImmunoblottingChromosomes, Human, Pair 14MitochondriaGreen Fluorescent ProteinsTransgenesbcl-X Proteinbcl-2-Associated X ProteinMice, NudeCARD Signaling Adaptor ProteinsProto-Oncogene Proteins c-mycProto-Oncogene Proteins c-aktTumor Suppressor ProteinsBlotting, Northern