Cyclin-Dependent KinasesCyclin-Dependent Kinase 2Cyclin-Dependent Kinase 5Cyclin-Dependent Kinase 4TransfectionCDC2-CDC28 KinasesCell Line, TumorMice, TransgenicGene ExpressionPhosphorylationMolecular Sequence DataSignal TransductionCell CycleCyclinsRNA, MessengerProtein-Serine-Threonine KinasesCell LineApoptosisCell Cycle ProteinsCyclin-Dependent Kinase 6CDC2 Protein KinaseTranscription FactorsMutationBlotting, WesternGene Expression Regulation, NeoplasticUp-RegulationCells, CulturedGene Expression RegulationProto-Oncogene ProteinsBase SequenceAmino Acid SequenceProtein BindingRNA, Small InterferingCell ProliferationDNA-Binding ProteinsReverse Transcriptase Polymerase Chain ReactionCyclin EPromoter Regions, GeneticCyclin-Dependent Kinase Inhibitor p27Cyclin D1ImmunohistochemistryNuclear ProteinsCell DivisionG1 PhaseTumor Cells, CulturedDown-RegulationCyclin-Dependent Kinase 9RNA InterferenceCarrier ProteinsPhenotypeTranscription, GeneticRecombinant Fusion ProteinsTumor Suppressor Protein p53HeLa CellsEnzyme ActivationCyclin-Dependent Kinase Inhibitor p21Membrane ProteinsTumor Suppressor ProteinsS PhaseCell DifferentiationAdenoviridaeGene Expression Regulation, EnzymologicMice, Inbred C57BLRecombinant ProteinsGene Knockdown TechniquesDNA PrimersCell NucleusEnzyme InhibitorsMitosisProto-Oncogene Proteins c-bcl-2Neoplasm ProteinsMicrotubule-Associated ProteinsCloning, MolecularProtein Structure, TertiaryBreast NeoplasmsTrans-ActivatorsRepressor ProteinsCyclin DGenetic VectorsNerve Tissue ProteinsCyclin-Dependent Kinase 8Cell SurvivalCyclin-Dependent Kinase Inhibitor p16ImmunoprecipitationIntracellular Signaling Peptides and ProteinsCell Transformation, NeoplasticImmunoblottingGene AmplificationTranscriptional ActivationSaccharomyces cerevisiae ProteinsTime FactorsCyclin BDNA, ComplementaryCell MovementSequence Homology, Amino AcidModels, BiologicalProtein TransportReceptor, erbB-2Cyclin D3Mice, Knockout