• Recommendations From the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. (medscape.com)
  • Metformin and combined oral contraceptive pills in the management of polycystic ovary syndrome: a systematic review and meta-analysis. (medscape.com)
  • Abstract Objective Insulin resistance is a common feature of polycystic ovary syndrome (PCOS). (elsevierpure.com)
  • You can also get a condition called polycystic ovary syndrome (PCOS), in which your ovaries make many small cysts with immature eggs in them. (webmd.com)
  • The history will usually include behavioral changes and signs of estrus that have taken place even after a successful surgical removal of the ovaries and uterus. (petmd.com)
  • Most ovarian cancers are either epithelial carcinomas (cancer that begins in the cells on the surface of the ovary) or malignant germ cell tumors (cancer that begins in egg cells). (cancer.gov)
  • Ovary surface epithelial tumor tissue array (1.5mm), 48 cases of benign and malignant tumors. (delos.info)
  • Designed for IHC or ISH based protein or RNA tissue profiling in benign and malignant ovary surface epithelial tumors. (delos.info)
  • Pantomics Array Description: Nervous system tumor tissue array consists of 48 cases of benign and malignant tumors of the nervous system. (delos.info)
  • Pantomics Array Description: Testis tumor tissue array, set 1, containing 69 cases of testis germ cell tumors, 18 cases of non-tumor. (delos.info)
  • Pantomics Array Description: Stomach cancer tissue array containing 48 cases of paired primary and metastatic tumors (in. (delos.info)
  • Epithelial tumors form in the tissue around your ovaries. (webmd.com)
  • The ovaries are uncovered in the peritoneal cavity but are tethered to the body wall via the suspensory ligament of the ovary which is a posterior extension of the broad ligament of the uterus. (wikipedia.org)
  • The suspensory ligament of the ovary (infundibular pelvic ligament) attaches the ovary to the pelvic sidewall. (medscape.com)
  • Nerve supply to the ovaries runs with the vasculature via the suspensory ligament of the ovary, entering the ovary at the hilum. (medscape.com)
  • An ovariohysterectomy is a surgical procedure in which the uterus and ovaries are removed from a female cat. (petmd.com)
  • Right away, the doctor recommended surgery to remove her uterus and ovaries. (cdc.gov)
  • We compared samples of testes, adipose tissue and liver from immature and peripubertal males, adrenal cortex from peripubertal males, ovaries from cyclic females and adipose tissue from peripubertal females. (inra.fr)
  • Very few differences were observed between transcriptional patterns of peripubertal testes and adrenal glands as well as between male and female fat tissues. (inra.fr)
  • It also shows that porcine adrenal glands produce essentially corticosteroids and that fat tissue is unable to produce de novo steroids. (inra.fr)
  • The ovaries, adrenal glands, and fat tissues produce estrogen. (medicalnewstoday.com)
  • The diaphragm divides the chest cavity from the abdominal cavity in mammals through a partition of skeletal muscle and connective tissue. (microscopyu.com)
  • The capsule is of dense connective tissue and is known as the tunica albuginea. (wikipedia.org)
  • Evaluating the Efficacy of Platelet-Rich Fibrin Matrix versus Subepithelial Connective Tissue Grafts in Den. (medscimonit.com)
  • Ovotestes are usually compartmentalized, with connective tissue separating the ovarian components from the testicular components. (medscape.com)
  • The cortex is made of tightly packed connective tissue. (medscape.com)
  • The stroma of this cortical connective tissue is composed of spindle-shaped fibroblasts that respond to hormonal stimulation in a way different from that of other fibroblasts in the body. (medscape.com)
  • It was found that the mice that received the ovarian tissue did not develop cancer, while all those that received the lymph tissue did. (progress.org.uk)
  • C: Tumor either Stage IA or Stage IB, but with tumor on the surface of one or both ovaries, or with capsule ruptured, or with ascites containing malignant cells or with positive peritoneal washings. (medscape.com)
  • however, the expression in normal and malignant adult tissues has not been examined in detail. (nature.com)
  • Here, we examined the expression of the HE4 gene and protein in a large series of normal and malignant adult tissues by oligonucleotide microarray and tissue microarray, respectively. (nature.com)
  • Here, we used oligonucleotide and tissue microarrays to survey HE4 gene and protein expression in a large group of malignant and normal tissues from adults. (nature.com)
  • This involves assessing the size of the tumor and whether the cancer has spread beyond the ovaries and fallopian tubes. (medicalnewstoday.com)
  • Stage 1 ovarian cancer is in one or both ovaries or fallopian tubes. (medicalnewstoday.com)
  • If it is in both ovaries or fallopian tubes, the subcategory is 1b. (medicalnewstoday.com)
  • Stage 3 ovarian cancer is in one or both ovaries or fallopian tubes or the lining of the abdominal cavity, which is called the peritoneum. (medicalnewstoday.com)
  • However, Kenya has already drafted new legislation which covers the donation of organs and tissues from both living and deceased donors, and eight Member States8 intend to adopt new legal requirements. (who.int)
  • These bones surround lower belly organs, such as the bladder and bowels, and female organs such as the uterus (womb) and ovaries. (msdmanuals.com)
  • The ovaries are the female pelvic reproductive organs that house the ova and are also responsible for the production of sex hormones. (medscape.com)
  • Meanwhile, another research project has shown that ovarian tissue transplanted into the arm of women before cancer treatment may prevent premature menopause in younger women and perhaps also preserve fertility. (progress.org.uk)
  • The ovaries also secrete hormones that play a role in the menstrual cycle and fertility. (wikipedia.org)
  • Since the ovaries are able to regulate hormones, they also play an important role in pregnancy and fertility. (wikipedia.org)
  • Scientists hope to use 3D-printed ovaries to restore fertility and hormone production in women - particularly those who have undergone cancer treatment, or had childhood cancer. (abc.net.au)
  • She said it was also hoped human bioprosthetic ovaries could be used to help restore fertility to women with premature ovarian failure. (abc.net.au)
  • Every month, a woman's ovaries produce hormones that tell the cells lining the uterus to swell and get thicker. (medlineplus.gov)
  • These growths stay in your body, and like the cells in the lining of your uterus, these growths react to the hormones from your ovaries. (medlineplus.gov)
  • Because the ovaries are a major producer of testosterone, the decrease in hormones produced by the ovaries associated with menopause means that some pre- and post-menopausal women may experience low testosterone levels. (healthline.com)
  • In many women, the ovaries continue to produce hormones like testosterone. (healthline.com)
  • At puberty, the ovary begins to secrete increasing levels of hormones. (wikipedia.org)
  • In turn, the pituitary gland releases hormones to the ovaries. (wikipedia.org)
  • From this signaling, the ovaries release their own hormones. (wikipedia.org)
  • If such tissue remains functional and continues to secrete hormones, estrus behavior will continue. (petmd.com)
  • Some boys may develop gynecomastia due to an imbalance of sex hormones , tissue responsiveness or obesity . (wikipedia.org)
  • Each month, the ovaries go through a series of stages, depending on stimulation by the anterior pituitary hormones the follicle stimulating hormone (FSH) and the luteinizing hormone (LH). (medscape.com)
  • METHODS: We have analysed short- and long-read RNA sequencing data from breast tumours, breast cancer cell lines, and normal tissues to create a. (lu.se)
  • METHODS: We have analysed short- and long-read RNA sequencing data from breast tumours, breast cancer cell lines, and normal tissues to create a comprehensive annotation of ER transcripts and combined it with experimental studies of full-length protein and six alternative isoforms. (lu.se)
  • Follicle cysts of the ovary are the most common cystic structures found in healthy ovaries. (medscape.com)
  • A cross-section of the ovary reveals many cystic structures that vary in size. (medscape.com)
  • Tissue from the lymph nodes of the women was grafted into another group of the mice as a control. (progress.org.uk)
  • Exploration of steroidogenesis-related genes in testes, ovaries, adrenals, liver and adipose tissue in pigs. (inra.fr)
  • Downregulated adipose tissue expression of browning genes with increased environmental temperatures. (medscape.com)
  • The goal of this study was to determine whether the core elements of the insulin signal transduction cascade were differentially expressed in subcutaneous adipose tissue (SAT) between PCOS and controls. (elsevierpure.com)
  • Materials/methods Quantitative real-time PCR for 36 insulin signaling pathway genes was performed in subcutaneous adipose tissue from 22 white PCOS and 13 healthy controls. (elsevierpure.com)
  • Results Genes in the insulin signaling pathway were not differentially expressed in subcutaneous adipose tissue between PCOS and controls (P 0.05 for all). (elsevierpure.com)
  • Conclusions Differential expression of core insulin signaling pathway components in subcutaneous adipose tissue is not a major contributor to the pathogenesis of PCOS. (elsevierpure.com)
  • 833 When an oocyte completes its maturation in the ovary, a surge of luteinizing hormone is secreted by the pituitary gland which stimulates the release of the oocyte through the rupture of the follicle, a process called ovulation. (wikipedia.org)
  • Similarly, at least a two-fold overexpression of TEF1A2 was noticed in approximately 30% of the human cancer tissue samples (colon, lungs, ovary, kidney and rectum) that were represented on a cancer profiling array (BD Biosciences, Palo Alto, CA) consisting of 241 paired cDNA samples generated from cancer/non-cancer tissues. (cdc.gov)
  • The body uses estrogen in the formation of breast tissue. (medicalnewstoday.com)
  • The testes primarily release testosterone , and the ovaries predominantly dispense estrogen . (wikipedia.org)
  • This pruritus may also produce secondary lesions as mechanical dermatitis of the perianal or vulvar tissues (15). (who.int)
  • BioChain's Genomic DNAs are available from human tumor tissues. (biochain.com)
  • Presently, we have investigated the expression profile of TEF1A2 using a panel of human cancer cell lines and tumor tissues. (cdc.gov)
  • Other structures and tissues of the ovaries include the hilum. (wikipedia.org)
  • The ovarian artery and vein enter and exit the ovary at the hilum. (medscape.com)
  • We quantified Se concentrations in muscle, liver and ovary of the demersal cyprinid Sacramento Splittail from six regions in the SFE at three time points to evaluate Se exposure risk. (usgs.gov)
  • Relationships between tissues varied among regions for muscle and liver and muscle and ovary, but a single global relationship could be defined for ovary and liver Se concentrations. (usgs.gov)
  • Our results suggest that the proposed EPA Se criteria for muscle tissue in Splittail may be under-protective as it would not have predicted exceedances in liver or ovary tissue and that the relationship between muscle tissue and ovary and liver may be Se concentration and seasonal dependent. (usgs.gov)
  • IR and compensatory hyperinsulinaemia have differing pathogeneses in various tissues, and IR varies among different PCOS phenotypes. (biomedcentral.com)
  • We searched PubMed, Google Scholar, Elsevier, and UpToDate databases in this review, and focused on the pathogenesis of IR in women with PCOS and the pathophysiology of IR in various tissues. (biomedcentral.com)
  • PCOS is a heterogeneous disease characterized by hyperandrogenism, dysfunctional ovulation, and polycystic ovary morphology, accompanied by metabolic abnormalities, such as insulin resistance (IR) and obesity. (biomedcentral.com)
  • This paper aims to summarize recent findings on the involvement of IR in the occurrence and development of PCOS and the mechanism of IR in various tissues. (biomedcentral.com)
  • The many components of these pathways have not been comprehensively analyzed for differential expression in insulin-responsive tissues in PCOS. (elsevierpure.com)
  • When you have PCOS, you may not have monthly periods and your ovaries may not release eggs regularly. (webmd.com)
  • B. Tumor of one or both ovaries with histologically confirmed implants of abdominal peritoneal surfaces, none exceeding 2 cm in diameter. (medscape.com)
  • Histologically, the ovary has 2 main sections: the outer cortex and inner medulla. (medscape.com)
  • These discrepancies can be manifested in different gonadal combinations, including ovotestis with ovary, ovary and testis, bilateral ovotestis, and ovotestis and tesis. (medscape.com)
  • The gonads present may be bilateral ovotestes, or they may be a combination of a unilateral ovary or testis with an ovotestis on the contralateral side. (medscape.com)
  • Additionally, testicular and ovarian tissue may develop on the same side of the pelvis as a separate ovary and testis. (medscape.com)
  • Tumor involving one or both ovaries with peritoneal implants outside the pelvis and/or positive retroperitoneal or inguinal nodes. (medscape.com)
  • The ovaries lie within the peritoneal cavity, on either side of the uterus, to which they are attached via a fibrous cord called the ovarian ligament. (wikipedia.org)
  • It is also related to peritoneal cancer, which is cancer of the tissues that line the abdomen. (msdmanuals.com)
  • Using bioengineering, instead of transplanting from a cadaver, to create organ structures that function and restore the health of that tissue for that person, is the holy grail of bioengineering for regenerative medicine. (abc.net.au)
  • Müllerian duct structures typically develop on the gonadal side not containing testicular tissue. (medscape.com)
  • Wolffian duct structures tend to be observed on the gonadal side containing functioning testicular tissue. (medscape.com)
  • Follicular cells are flat epithelial cells that originate from surface epithelium covering the ovary. (wikipedia.org)
  • A germinal layer coats the entire ovary, made of cuboidal epithelial cells. (medscape.com)
  • The team, led by Dr Samuel Kim, took ovarian tissue from 18 women with lymphoma, and grafted it into a strain of mice that did not have working immune systems. (progress.org.uk)
  • The research, which is published in the journal Human Reproduction, indicates that preserving ovarian tissue from cancer patients before treatment, and storing this for later transplant is safe, because the ovarian tissue did not cause cancer to develop. (progress.org.uk)
  • Dr Kutluk Oktay and colleagues from Cornell University, US, transplanted ovarian tissue to the arms of two women, one with cervical cancer and the other with benign ovarian cysts. (progress.org.uk)
  • The first woman in the world to become pregnant following a transplant of her own frozen, thawed ovarian tissue has given birth to a healthy baby girl. (progress.org.uk)
  • However, some female cats continue to exhibit the behavioral and/or physical signs pertaining to estrus even after such a surgery, and are found to have some ovarian tissue that had not been removed during surgery and was left behind. (petmd.com)
  • In addition, ultrasound can be used to determine whether any ovarian tissue residues are present. (petmd.com)
  • However, in some cases abdominal surgery may be required to confirm the presence of ovarian tissue. (petmd.com)
  • After reaching a confirmatory diagnosis, your veterinarian will consult with you about a second round of surgery to remove any left-over functioning ovarian tissue. (petmd.com)
  • Prognosis is very good after the removal of ovarian tissue residues has been performed. (petmd.com)
  • Compared to standard plans, ovary-sparing plans had lower mean bilateral ovary doses (MBOD) (652 versus 483 cGy, p=0.007) but higher bone doses (mean V50: 8.5% versus 6.9%, p=0.049) and lower conformity indexes (1.12 versus 1.19, p=0.009). (johnshopkins.edu)
  • Cancers of the prostate, thyroid, bladder and soft tissues decreased over the study period. (who.int)
  • En revanche, le nombre de cancers de la prostate, de la thyroïde, de la vessie et des tissus mous a diminué au cours de la période de l'étude. (who.int)
  • Ovarian cysts are fluid-filled or semi-solid pockets in or on one of your ovaries. (webmd.com)
  • For women of childbearing age, simple unilateral oophorectomy via laparoscopy or laparotomy is adequate, provided that the contralateral ovary appears grossly normal. (medscape.com)
  • In women before menopause, 50% of testosterone is produced by the ovaries and released directly into the blood stream. (wikipedia.org)
  • Collectively, these results indicated that: 1) TEFA12 is significantly overexpressed in human tumor cell lines and tumor tissue samples, 2) the cellular expression level of TEF1A2 may be used as a tumor marker, and 3) the anti-apoptotic role of TEF1A2 may potentially be responsible for its oncogenic function. (cdc.gov)
  • It is typically felt on one side of the abdomen (the side where the ovary is releasing the egg), and the intensity can range from mild to severe. (medicinenet.com)
  • Some women with a lot of tissue in their pelvis have no pain at all, while some women with milder disease have severe pain. (medlineplus.gov)
  • The surface of the ovaries is covered with a membrane consisting of a lining of simple cuboidal-to-columnar shaped mesothelium, called the germinal epithelium. (wikipedia.org)
  • Several paired ligaments support the ovaries. (medscape.com)
  • The part of the broad ligament of the uterus that covers the ovary is known as the mesovarium. (wikipedia.org)
  • The posterior portion of the broad ligament forms the mesovarium, which supports the ovary and houses its arterial and venous supply. (medscape.com)
  • The ovary progresses through many stages beginning in the prenatal period through menopause. (wikipedia.org)
  • the ovaries, covered by a modified peritoneum, are approximately 3-5 cm in length during childbearing years and become much smaller and then atrophic once menopause occurs. (medscape.com)
  • A female mouse's ovaries were removed and replaced with 3D printed bioprosthetic ones using gelatin as the 'ink' and using eggs from different mice - enabling it to ovulate, conceive pups and give birth, the United States researchers said. (abc.net.au)
  • The ovaries are responsible for housing and releasing ova, or eggs, necessary for reproduction. (medscape.com)
  • A diagnosis of OT-DSD is based solely on the presence of ovarian and testicular tissue in the gonad and not on the characteristics of the internal and external genitalia, even if ambiguous. (medscape.com)
  • Pantomics Array Description: Soft tissue tumor tissue array, set 1, non-overlapping with SFT962, 96 cores, 48 cases of benign and. (delos.info)
  • We were also the first to develop a functional soft tissue transplant using 3D printing,' she said. (abc.net.au)
  • The top five cancers ranked on the 5-year relative up information at five years from the incidence date survival were Hodgkin disease (59%), thyroid (49%), ranged from 100% for unspecified leukaemia to 59% soft tissue (47%), non-melanoma skin (39%) and for non-melanoma skin cancer. (who.int)
  • Two of them were expressed only in testes, ovaries and adrenals: CYP11A1 and CYP11B. (inra.fr)
  • Main differences between ovaries and testes were observed for HSD17B1/2/3, AKR1C-pig6 and sulfotransferase genes (SULT2A1/SULT2B1). (inra.fr)
  • In the ovary, both paralogs were detected in germinal and somatic cells. (nature.com)
  • In some cases, the cancer develops on the surface of the ovary, or cancerous cells slough off and doctors detect them in abdominal or pelvic fluid. (medicalnewstoday.com)
  • Ovaries, when found, can occupy the normal abdominal position, although they may occasionally be found at the internal inguinal ring. (medscape.com)
  • DCEG researchers conduct studies on cancers of the ovary, also known as ovarian cancer. (cancer.gov)
  • The ovaries are surrounded by a capsule, and have an outer cortex and an inner medulla. (wikipedia.org)
  • Some genes were shown to have a tissue-specific expression. (inra.fr)
  • We found that knockdown of Bonus in early oogenesis results in severe defects in ovarian development and in ectopic expression of genes that are normally repressed in the germline, demonstrating its essential function in the ovary. (elifesciences.org)
  • The ovary is an organ in the female reproductive system that produces an ovum. (wikipedia.org)
  • Organ and tissue donation and transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ or tissue. (who.int)
  • https://en.wikipedia.org/wiki/Organ_transplantation. (who.int)
  • 4 World Health Assembly - Resolution WHA63.22 on Human organ and tissue transplantation, May 2010. (who.int)