Ovary early follicle morphogenesis. Medical search. Frequent questions

It participates in androgen synthesis enhancing LH action in the ovary and testis. (wikipedia.org)
These discrepancies can be manifested in different gonadal combinations, including ovotestis with ovary, ovary and testis, bilateral ovotestis, and ovotestis and tesis. (medscape.com)
The gonads present may be bilateral ovotestes, or they may be a combination of a unilateral ovary or testis with an ovotestis on the contralateral side. (medscape.com)
Additionally, testicular and ovarian tissue may develop on the same side of the pelvis as a separate ovary and testis. (medscape.com)
Interestingly, in the gonad, it is also the only gene that has been found expressed uniquely in the ovary compared to the testis, and likely functions as an antagonist of the testis-determining SOX9 in gonadal development [ 4 ]. (biomedcentral.com)
In the developing male (XY) gonad, sex-determining region of the Y (SRY) protein acts to up-regulate expression of the related gene, SOX9 , a transcriptional regulator that in turn initiates a downstream pathway of testis development, whilst also suppressing ovary development. (plos.org)
Analysis of XY byg/byg gonads at 11.5 d post coitum reveals a growth deficit and a failure to support mesonephric cell migration, both early cellular processes normally associated with testis development. (plos.org)

FSH stimulates the secretion of inhibin from the granulosa cells of the ovarian follicles in the ovaries. (wikipedia.org)
The granulosa cells and theca cells of the developing antral follicle and the steroidogenic cells of the corpus luteum produce and respond to angiogenic factors and vasoactive peptides. (biomedcentral.com)

Epithelial tubes are the infrastructure for organs and tissues and tube morphogenesis requires exact orchestration of cell signaling shape migration and adhesion. (ecologicalsgardens.com)
Furthermore since ovaries from well-nourished females contain all phases of egg chamber development and since egg chambers can be dissected and cultured outside of the ovary this system is ideal for investigating epithelial tube patterning formation and development (Berg 2005 Fig. 1 twin peaks (ttktwk) a female sterile mutation affects gene manifestation during late oogenesis. (ecologicalsgardens.com)
In addition to these basic aspects, our work is also medically relevant since 80% of cancers have an epithelial origin and deregulation of the mechanisms controlling their growth or their morphogenesis are involved in tumor development. (igred.fr)
We study on the one hand F-actin cytoskeleton function and dynamics at the apical domain and cell junctions of follicular epithelial cells, in contact with the germ cells during the early elongation of the follicles. (igred.fr)
How epithelial cells actively respond to mechanical constraints by adjusting how they generate force is important to understand tissue morphogenesis. (nature.com)

Premature ovarian failure is the extreme state of complete primordial follicle depletion. (medscape.com)

Inhibin B reaches a peak in the early- to mid-follicular phase, and a second peak at ovulation. (wikipedia.org)
These protease-induced decreases in IGFBP-4 and -5 likely cause increased levels of bioavailable (or free) IGFs that stimulate steroidogenesis and mitogenesis in developing dominant follicles, which ultimately prepare the follicle(s) and oocyte(s) for successful ovulation and fertilization. (bioone.org)
Following ovulation the neovascularization during the early stages of corpus luteum development has been compared to the rapid angiogenesis observed during tumor formation. (biomedcentral.com)
Additionally, reproductive hormones regulate RAS activity in the cellular physiological function of ovarian follicles during pre-ovulatory maturation and ovulation. (encyclopedia.pub)
During reproductive processes, ovulation and follicle numbers are regulated by the hypothalamic-pituitary-gonadal axis (HPG-axis) and involve sequential waves of endocrine events, including changes in progesterone, follicle-stimulating hormone (FSH), and luteinizing hormone (LH) levels [ 5 ]. (biomedcentral.com)
factor(s) relies on gene transcription that oocytes largely Oocytes spend most of their time quiescent in primordial perform during follicular growth prior to ovulation, and follicles, mature over days or weeks during follicular the transcriptional activities of oocytes may be influ- growth and then become quiescent again near the enced by maternal age. (gotomydoctor.com)

Specifically, we use follicular cells of the Drosophila ovaries as an in vivo epithelium model. (igred.fr)
The Drosophila follicle-cell epithelium provides an appropriate model system for studying the potential role of electrochemical signals, like intracellular pH (pH i ) and membrane potential (V mem ), during development. (biomedcentral.com)
Our data show that in the Drosophila follicle-cell epithelium stage-specific pH i - and V mem -gradients develop which result from the activity of several ion-transport mechanisms. (biomedcentral.com)

Although earlier studies show that Mirror patterns the follicular epithelium prior to DA tubulogenesis we display that Mirror has an self-employed novel part in tube development involving positive rules of ovary. (ecologicalsgardens.com)
Anatomically, this epithelium surrounds the germ cells within the reproductive organ, forming 'ovarian follicles' or 'egg chambers', precursors of the future egg. (igred.fr)
Interestingly, the elongation of the ovarian follicle, which progressively matures from a spherical to an elongated form, is generated by the follicular epithelium. (igred.fr)
On the other hand, we analyze the involvement of the Dystrophin-Dystroglycan protein complex and the basal domain of the epithelium in the later follicle elongation phase and especially its implication in planar cell polarity and extracellular matrix organization. (igred.fr)
For example, purely physical mechanisms can account for branching morphogenesis of the embryonic mouse airway epithelium, when cultured ex vivo in the absence of biochemical patterning 14 . (nature.com)

In some species (e.g., bovine), evidence indicates that decreases in IGFBP-4 and -5 levels in estrogen-dominant preovulatory follicles are likely due, in part, to increased protease activity, whereas lower levels of IGFBP-2 are not due to increased proteolysis. (bioone.org)
Increased IGFBP-4 and -5 protease along with lower amounts of IGFBP-4 binding activity and greater amounts of free IGF-I are some of the earliest developmental changes documented in bovine growing antral follicles. (bioone.org)
Expression and localization of vascular endothelial growth factor and angiopoietin-1 and their receptors FLT-1, FLK-1, and TIE-2 in bovine ovaries during follicular and luteal development. (mcmaster.ca)

When a young woman reaches puberty around age 10 to 13, a promary oocyte is discharged from one of the ovaries every 28 days. (wikibooks.org)

The potential clinical applications of research directed on corpus luteum endothelial cells are intriguing considering reproductive processes in which vascular dysfunctions may play a role such as ovarian failure, polycystic ovary syndrome (PCOS), and ovarian hyperstimulation syndrome (OHSS). (biomedcentral.com)
The corpus luteum is a temporary endocrine gland in the ovary. (encyclopedia.pub)
Thus, we have reviewed the role of RAS protein related to the biological events of the corpus luteum in the ovary. (encyclopedia.pub)

Ovarian insufficiency is a failure of the ovary to function adequately in a woman younger than 40 years, in its role either as an endocrine organ or as a reproductive organ. (medscape.com)
The human ovary functions as both a reproductive organ and an endocrine organ. (medscape.com)

Though this method can provide insights into spacial and temporal alterations that occur during development of sweeper fish embryo and larvae, it can also be applied to investigate early developmental processes and other model organisms. (jove.com)
In the early embryo syncytium, rapid DNA replication and nuclear divisions occur, generating up to 5000 nuclei per embryo. (cherrybiotech.com)
This 1915 paper by Kingsbury describes early human embryo pharynx development using human embryos from the Harvard Collection and Cornell Collection. (edu.au)
In some lower animals the amount of yolk is less in egg, so that the embryo hatches in earlier stages of development, called a larva. (biologydiscussion.com)
We identified a mouse mutant that causes embryonic gonadal sex reversal: the development of ovaries in an XY embryo. (plos.org)

For this, we analyze the modes of communication between the germ cells and the follicular cells, allowing the synchronization of their growth during the development of the ovarian follicles and thus ensuring the homeostasis of the reproductive organ. (igred.fr)
The ovary is a dynamic female reproductive organ that undergoes many structural and functional transformations as it fulfills its two significant roles of producing female gametes and synthesizing sex steroid hormones [ 1 ] . (encyclopedia.pub)

Berg 2005 The apical lumens of these tubes act as molds for the DAs of the adult eggshell so although the FCs slough off during oviposition the number position and morphology of the DA constructions on laid eggs provide physical evidence for the effectiveness of tube patterning and morphogenesis during oogenesis. (ecologicalsgardens.com)
We found that knockdown of Bonus in early oogenesis results in severe defects in ovarian development and in ectopic expression of genes that are normally repressed in the germline, demonstrating its essential function in the ovary. (elifesciences.org)

Primary ovarian insufficiency (POI) (premature ovarian failure, premature menopause, or early menopause) is a condition characterized by amenorrhea, hypoestrogenism, and elevated serum gonadotropin levels in women younger than 40 years. (medscape.com)

Interestingly, ovaries occur more commonly on the left side than the right. (medscape.com)

Ovotestis refers to the histology of a gonad that contains both ovarian follicles and testicular tubular elements. (medscape.com)

BACKGROUND: Monopterus albus is a hermaphroditic fish with sex reversal from ovaries to testes via the ovotestes in the process of gonadal development, but the molecular mechanism of the sex reversal was unknown. (bvsalud.org)
Ovaries and ovarian portions of ovotestes appear normal and demonstrate follicular growth with estradiol production. (medscape.com)

Aging is associated with a decline in the number of ovarian follicles, menstrual irregularities, ovarian hormonal deficiency, anovulation, decreased fertility, and, finally, a complete and irreversible cessation of menses known as menopause, usually occurring at a mean age of 51 years. (medscape.com)

The presence of estradiol in developing ovarian follicles usually inhibits spermatogonia development in adjacent or contralateral seminiferous tubules. (medscape.com)
Sensory circuits are typically established during early development, yet how circuit specificity and function are maintained during organismal growth has not been elucidated. (sdbonline.org)

Ovaries, when found, can occupy the normal abdominal position, although they may occasionally be found at the internal inguinal ring. (medscape.com)
Typical early manifestations are nonspecific (e.g., umbilical or inguinal hernia, frequent upper respiratory tract infections before age 1 year). (nih.gov)

Occult primary ovarian insufficiency presents as unexplained infertility in a patient with a normal basal serum follicle-stimulating hormone (FSH) level. (medscape.com)

While deteriorate as the potential mother ages, compromising, the receptivity of the uterus and the ovarian reserve of for example, the function of the chromosomal apparatus follicles can explain the 'maternal age effect' in part, it is or the ability to scavenge reactive oxygen species known that age-related decline of a female's fertility is resulting from mitochondrial reactions ( also rooted in the quality and developmental potential of her oocytes. (gotomydoctor.com)

Activin is produced in the gonads, pituitary gland, placenta, and other organs: In the ovarian follicle, activin increases FSH binding and FSH-induced aromatization. (wikipedia.org)
Activin also regulates the morphogenesis of branching organs such as the prostate, lung, and especially kidney. (wikipedia.org)
It is therefore important to understand how our genes sculpt these organs into a specific form (morphogenesis) and with an appropriate size (growth). (igred.fr)

As defined by the World Health Organization, ovarian insufficiency can be caused by a primary disorder in the ovary or it can occur as a result of secondary causes. (medscape.com)

Whether the hormonal control of PAPP-A production/activity by the ovary differs between monotocous and polytocous animals will require further study. (bioone.org)

The study of mechanisms controlling growth and morphogenesis is based on dynamic multi-scale biological processes (molecular, cellular and tissular) and requires approaches involving developmental biology, genetics, cell biology and biophysics. (igred.fr)
We illustrate where such mechanisms of pattern formation arise in biological systems from cellular to tissue scales, with an emphasis on morphogenesis. (mpi-cbg.de)

The ovaries of a newborn baby girl contain about one million oocytes. (wikibooks.org)
Oocytes were collected from slaughterhouse-derived ovaries, matured in vitro, and injected with frozen-thawed stallion sperm. (bioone.org)

Earlier studies have indicated that fertility traits in sheep can be regulated by individual genetic markers with major effects, which are known as fecundity genes [ 10 , 11 ], or by polygenic effects, particularly in prolific breeds, such as Finnsheep and Romanov [ 12 ]. (biomedcentral.com)

2. Understand the morphogenetic mechanisms leading to elongation of ovarian follicles. (igred.fr)

ESP is the earliest known protein to be recognized as a marker for the specification of the equatorial segment, and it allows this region to be traced through all phases of acrosomal biogenesis. (bioone.org)
This mutant, which we called boygirl ( byg ), was shown to contain an early stop codon that disrupts the autosomal gene encoding MAP3K4, a component of the mitogen-activated protein kinase (MAPK) signaling pathway. (plos.org)

This work evaluated the effect of ex situ management on neurogenesis (cell proliferation in the dorsal and medial ventricular zones, neuronal integration in the dorsomedial and medial cortices), ovary cell proliferation, body size (mass and length) and self-righting ability. (frontiersin.org)

Early stages of implantation are not available. (ucsd.edu)
Cerebral blood flow appears to be increased in the very early stages of meningitis, but subsequently it decreases, where the frame rate is determined by practical considerations 15 Hz is the minimum observed value for reasonable minimization of motion artifacts while imag- ing inside a beating heart. (forex-consultant.com)

The vascular endothelium of the mature ovarian follicle maintains the capacity for rapid growth in response to angiogenic signals elaborated during the periovulatory process. (biomedcentral.com)

Ovarian insufficiency is considered primary if the ovary fails to function normally in response to appropriate gonadotropin stimulation provided by the hypothalamus and pituitary. (medscape.com)

Allowing comprehension and predicting of human responses earlier, while also offering ethical alternatives to animal testing. (cherrybiotech.com)
It was estimated that, as many as, 200 million years of human beings were present, already delineated in the ovaries of Eve. (biologydiscussion.com)

The identification and characterization of differentially expressed genes and miRNAs in the ovaries of sheep provided insights into genetic and environmental factors affecting prolificacy traits. (biomedcentral.com)

Its action in wound repair and skin morphogenesis is through stimulation of keratinocytes and stromal cells in a dose-dependent manner. (wikipedia.org)

Light microscopic immunofluorescent observations revealed that during acrosome biogenesis ESP first appears in the nascent acrosomal vesicle in early round spermatids and subsequently segregates to the periphery of the expanding acrosomal vesicle, thereby defining a peripheral equatorial segment compartment within flattened acrosomal vesicles and in the acrosomes of early and late cap phase, elongating, and mature spermatids. (bioone.org)
Based on these observations, we propose a new model of acrosome biogenesis in which the equatorial segment is defined as a discrete domain within the acrosomal vesicle as early as the Golgi phase of acrosome biogenesis. (bioone.org)

H&E stain of ovotestis demonstrating ovarian parenchyma (left) with multiple primary follicles and testicular parenchyma (right). (medscape.com)
Ovarian ultrasonography can be useful in the workup of patients with primary ovarian insufficiency, as it will identify those women with multifollicular ovaries and suggest the diagnosis of either autoimmune oophoritis or 17-20 desmolase deficiency. (medscape.com)

At present no proven method can determine that a woman has no primordial follicles remaining in the ovary, so, in effect, this term is merely a construct (ie, a concept that cannot be proven). (medscape.com)

Anatomy35

Organisms15

Diseases8

Chemicals and Drugs43

Analytical, Diagnostic and Therapeutic Techniques and Equipment14

Phenomena and Processes35

Disciplines and Occupations1

Information Science3

Testis7

Granulosa cells2

Epithelial5

Primordial follicle1

Ovulation6

Drosophila3

Epithelium5

Bovine3

Oocyte1

Corpus luteum3

Endocrine2

Embryo5

Reproductive2

Oogenesis2

Ovarian failure1

Interestingly1

Gonad1

Ovotestes2

Menstrual1

Development2

Inguinal2

Basal1

Maternal1

Organs3

Occur1

Hormonal1

Cellular2

Oocytes2

Fertility1

Mechanisms1

Protein2

Cell1

Stages2

Vascular1

Function1

Human2

Characterization1

Cells1

Vesicle2

Primary2

Woman1