• Malignant Brenner tumors are uncommon ovarian carcinomas and represent less than 5% of all Brenner tumors. (cap.org)
  • Most tumors are confined to the ovary at diagnosis, and malignant Brenner tumors have a better prognosis than other epithelial ovarian carcinomas. (cap.org)
  • subsequently, this group of tumors of the ovary were classified in 1973 by the World Health Organization as "low malignant potential ovarian tumor" [ 2 ] and, finally, in 2003 WHO separates them from carcinomas and call them borderline tumors. (intechopen.com)
  • Unlike the invasive carcinomas, borderline ovarian tumors are characterized by cytoplasmic and nuclear atypia, (element of differential diagnosis with benign tumors), absence of stromal invasion, (element of differential diagnosis with malignant tumors), unusual degree of proliferation of the epithelial cells with cellular stratification including remarkable architectural atypia and the formation of papillary protuberances. (intechopen.com)
  • The category of 'transitional cell carcinoma of the ovary' represents primary ovarian carcinomas in which definite urothelial features are identified, but no benign or borderline proliferating Brenner tumor are found. (surgpath4u.com)
  • The natural progression of these tumors also lend support to this theory, as Brenner tumors (even borderline and malignant) have a much better prognosis than transitional cell carcinomas of the ovary. (surgpath4u.com)
  • Transitional cell tumors of the ovary: a comparative clinicopathologic, immunohistochemical, and molecular genetic analysis of Brenner tumors and transitional cell carcinomas. (surgpath4u.com)
  • Reidel I, Czernobilsky B, Lifschitz-Mercer B. Brenner tumors but not transitional cell carcinomas of the ovary show urotehlial differentiation: immunohistochemical staining of urothelial markers, including cytokeratins and uroplakins. (surgpath4u.com)
  • Ovarian cancer is a rare disease, with carcinomas comprising approximately 90% of tumors and germ cell and stromal tumors accounting for the remainder. (uofmhealth.org)
  • The category of ovarian borderline tumor or tumor of low-malignant potential, which historically had been considered in the context of ovarian cancer, is now generally considered a nonmalignant entity, although it has a postulated relationship with the development of some histological subtypes of low-grade ovarian carcinomas. (uofmhealth.org)
  • Background: Non-epithelial malignant ovarian tumors and clear cell carcinomas, Brenner tumors, transitional cell tumors, and carcinoid tumors of the ovary are rare ovarian tumors (ROTs). (medipol.edu.tr)
  • However, the vast majority of malignant ovarian tumors (80%-85%) are classified as epithelial tumors (carcinomas). (biomedcentral.com)
  • In contrast, 80%-90% of ovarian carcinomas are detected after the age of 40, and 40% of these tumors are detected after the age of 65. (biomedcentral.com)
  • Ovarian carcinomas are characterized by a Müllerian morphology although the ovaries do not originate from the Müllerian ducts. (biomedcentral.com)
  • Cancerous epithelial tumors are carcinomas. (news-medical.net)
  • Epithelial ovarian carcinomas (EOC's) account for 85 to 90 percent of all cancers of the ovaries. (news-medical.net)
  • Carcinomas arising in mature cystic teratomas of the ovaries from nine women were examined for the presence of p53 mutations. (keyopinionleaders.com)
  • Type I tumors include low-grade serous, low-grade endometrioid, clear cell and mucinous carcinomas and type II include high-grade serous, high-grade endometrioid and undifferentiated carcinomas. (biomedcentral.com)
  • Malignant mixed mesodermal tumors (carcinosarcomas) are included in the type II category because their epithelial components are identical to the pure type II carcinomas. (biomedcentral.com)
  • A Rare Case of Grade 1 Endometrioid Adenocarcinoma of the Uterus With Omental Metastasis with Brenner Tumor of the Ovary in a Postmenopausal Female. (bvsalud.org)
  • Histologically, most of them are serous or mucinous, but endometrioid, clear cell, Brenner (transitional cell) or mixed histotypes can be also seen. (intechopen.com)
  • Admixtures of other surface epithelial tumors (serous, endometrioid) are common, thus, the transitional cell component must comprise over 50% of the tumor to be diagnosed as transitional cell carcinoma. (surgpath4u.com)
  • These IHC stuides have lead most authors to conclude that TCCs are a poorly-differentiated adenocarcinoma akin to other surface epithelial ovarian tumors such as serous and endometrioid types. (surgpath4u.com)
  • Ovarian yolk sac tumor associated with endometrioid carcinoma and mucinous cystadenoma of the ovary. (nih.gov)
  • This small percentage includes patients with stage IA or IB (grade 1) serous, mucinous, endometrioid, and Brenner tumors. (medscape.com)
  • Transitional cell carcinoma of the ovary (TCC of the ovary) is a rare type of ovarian cancer that has an appearance similar to urothelial carcinoma (also known as transitional cell carcinoma). (wikipedia.org)
  • Various studies have shown an association of Brenner tumor with endometrial hyperplasia , polyp , or early-stage carcinoma , probably due to its estrogen -secreting nature . (bvsalud.org)
  • Squamous cell carcinoma of the ovary is rare and usually arise from preexisting cystic teratomas, endometriosis or Brenner tumors which undergo carcinomatous degeneration in their epithelial elements. (koreamed.org)
  • A Brenner component was lacking, a feature of the diagnosis of transitional cell carcinoma of the ovary. (surgpath4u.com)
  • Transitional cell carcinoma represent a more aggressive neoplasm compared to malignant Brenner tumors. (surgpath4u.com)
  • An unusual case of a borderline Brenner tumor associated with bilateral serous cystadenoma and endometrial carcinoma. (nih.gov)
  • 10 ] Further, among carriers of deleterious mutations in BRCA1 or BRCA2, increasing evidence suggests that many tumors previously classified as ovarian high-grade serous carcinoma may develop from malignant cells arising in the tubal epithelium (serous tubal intraepithelial carcinoma [STIC]), although these tumors continue to be referred to as ovarian cancers in most writings. (uofmhealth.org)
  • Reported rates of mucinous carcinoma diagnoses have declined dramatically, but expert pathology reviews suggest that this reflects increased recognition of metastases from occult gastrointestinal primary tumors to the ovary, rather than a true decline in rates of ovarian primary tumors. (uofmhealth.org)
  • However, when a malignant tumor with transitional morphology is encountered, the approach to diagnosis must essentially address two aspects: first, to establish whether a tumor in question is originating from a preexisting BT or a de novo transitional cell carcinoma (TCC) of the ovary and second in cases with widespread involvement of the pelvic organs, origin from the urinary bladder must be ruled out. (ijhi.org)
  • The immunohistochemical profile of the tumor including the solid islands was consistent with a TCC (strong ER+, WT1+, strong p16+, p53+, CK7−, and CK20−) [Figure 1] F-H. In diagnostic accordance with WHO 2014, the tumor was called a high-grade serous carcinoma with transitional cell morphology. (ijhi.org)
  • Carcinoma of the ovary is most common in women over age 60. (news-medical.net)
  • The most frequent histologic type was represented by high-grade serous carcinoma Rare primary ovarian tumors were represented by: adult granulosa cell tumor, clear cell carcinoma, sarcoma cancer by age serous-mucinous carcinoma and undifferentiated pleomorphic sarcoma 1. (metin2kiss.ro)
  • The earliest age of all patients with ovarian tumors was 31 years old for the mixed serous-mucinous carcinoma. (metin2kiss.ro)
  • Rupture of a mucinous cystadenoma or cystadenocarcinoma leading to the spread of tumor cells throughout the peritoneum . (amboss.com)
  • Benign epithelial tumors (adenoma and cystadenoma) are characterized by the absence of cell proliferation and invasion. (biomedcentral.com)
  • Some Brenner tumors may arise from the wall of a mucinous cystadenoma. (surgpath4u.com)
  • In Meigs syndrome, the type of ovarian syndrome is fibroma, whereas in pseudo-Meigs syndrome cystadenoma, thecoma or a granulosa tumor types are prominent in ovary 5 . (syndromespedia.com)
  • Cystadenoma cysts grow on the outer surface of the ovary and are benign (non-cancerous). (elispot.biz)
  • Mature teratomas (aka dermoid cysts) are germ cell tumors of the ovary that are both common and benign. (proprofs.com)
  • The ovaries consist of different types of tissue ( epithelial , germ cells, and sex cord tissue), which may give rise to benign or malignant tumors . (amboss.com)
  • These tumors are subdivided into three main categories: epithelial, germ cell, and sex-cord stromal tumors. (biomedcentral.com)
  • According to the 2014 World Health Organization (WHO) classification and tumor morphology, primary ovarian tumors are subdivided into three categories: epithelial (60%), germ cell (30%), and sex-cord stromal tumors (8%)[ 1 ]. (biomedcentral.com)
  • Malignant germ cell and sex-cord stromal tumors comprise approximately 10% of all malignant ovarian tumors. (biomedcentral.com)
  • Seminomas and testicular germ cell tumors were negative. (elsevierpure.com)
  • Neuron-specific enolase (NSE) was measured with an enzyme-immunoassay in sera from 54 patients with malignant (24 cases) and benign (30 cases) germ cell tumors of ovarian origin. (keyopinionleaders.com)
  • Ovarian teratoma is a benign or malignant tumor belonging to a group of germ cell tumors . (cancerwall.com)
  • This is the most common type of ovarian germ cell tumor . (cancerwall.com)
  • This theory suggests that tumors are anatomically distributed along the migration patterns of primordial germ cells [4] . (cancerwall.com)
  • There are 2 ovaries, with 1 located on each side of the uterus. (cancer.net)
  • The fallopian tubes are small ducts that connect the ovaries to the uterus. (cancer.net)
  • During ovulation, which typically happens monthly, an egg is usually released from 1 ovary and travels through a fallopian tube to the uterus. (cancer.net)
  • The frontal section shows the fallopian tubes, 2 small ducts that link the 2 ovaries (1 on each side) to the hollow, pear-shaped uterus. (cancer.net)
  • At the completion of childbearing, usually the remaining ovary and uterus are removed. (medscape.com)
  • The eggs travel from the ovaries through the fallopian tubes into the uterus, where a fertilized egg develops into a fetus. (uchealth.org)
  • This can include ovaries, fallopian tubes and the uterus. (knowcancer.com)
  • Solitary tumors of the uterus which arise de novo from the mesenchymal cells of the myometrium. (brainscape.com)
  • Endometriomas might form when a woman has endometriosis (a condition where the tissue that normally lines the uterus grows outside the uterus, often on the ovaries). (elispot.biz)
  • PCO, or polycystic ovary syndrome, is a condition that is typically characterized by enlarged ovaries, hirsutism (excessive hair growth), amenorrhea (absence of menstrual periods), obesity, and anovulation (lack of ovulation). (proprofs.com)
  • Polycystic Ovary Syndrome -- 22. (nshealth.ca)
  • When the ovaries make many small cysts, it's called polycystic ovary syndrome (PCOS). (elispot.biz)
  • A tumor can be cancerous or benign. (cancer.net)
  • A cancerous tumor is malignant, meaning it can grow, invade, and spread to other parts of the body. (cancer.net)
  • Are borderline ovarian tumors cancerous? (medicalnewstoday.com)
  • Ovarian tumors are named according to the type of cells the tumor started from and whether the tumor is benign or cancerous. (news-medical.net)
  • A teratoma tumour is a rare type of cancerous growth that can occur anywhere in the body. (keyopinionleaders.com)
  • Ovarian tumors are cancerous growths that form on a woman's ovaries. (knowcancer.com)
  • Surgery may be indicated to remove polyps/tumors, or parts of the colon or rectum to eliminate cancerous growths. (hermanwallace.com)
  • Small cysts are often present, but benign Brenner tumors are rarely predominantly cystic. (cap.org)
  • Follicles may be entirely normal up to 2.5 centimeters in size and should not be called cysts of the ovary. (wdxcyber.com)
  • Both tubal structures (hydrosalpinx, hydatids) and congenital broad ligament cystic masses (paramesonephric remnants) can appear to be ovarian cysts if the ovary is not seen in imaging separately on that side. (wdxcyber.com)
  • Follicle cysts of the ovary are the most common cystic structures found in healthy ovaries. (medscape.com)
  • A 2-year interim analysis from the International Ovarian Tumor Analysis Phase 5 (IOTA5) study showed that 80% of ovarian cysts considered benign on ultrasonography either disappeared or required no intervention. (medscape.com)
  • A systematic review and meta-analysis by Liu et al found that the malignancy rate, including borderline tumors, for simple ovarian cysts in postmenopausal women was approximately 1 in 10,000. (medscape.com)
  • Up to 1/3 of Brenner tumors contain mucinous elements (mucinous glands, cysts or co-existing mucinous adenocarcinomas). (surgpath4u.com)
  • These cysts usually go away on their own by the middle of the second trimester, but sometimes they stay on the ovary and - if they become large or cause symptoms - may need to be removed. (elispot.biz)
  • Ovarian cysts usually don't cause any problems during pregnancy, though if a cyst continues to grow it might rupture or twist or cause the ovary to twist (this twisting is called ovarian torsion). (elispot.biz)
  • Because ovarian neoplasms can show different pathologic features in the various areas of the neoplasm, the entire neoplasm is submitted for pathological examination which means removal of that entire ovary. (wdxcyber.com)
  • A non-metastasizing neoplasm that arises from the ovary. (icd9data.com)
  • Similar to other epithelial ovarian tumors, Benner tumors are classified as benign, borderline/atypical proliferative, or malignant. (cap.org)
  • Borderline/atypical proliferative Brenner tumors are often larger than benign Brenner tumors, with an average diameter of 18 cm. (cap.org)
  • Histologically, malignant Brenner tumors are associated with a benign or borderline/atypical proliferative Brenner tumor component. (cap.org)
  • Medical professionals may also refer to BOTs as atypical proliferative tumors or tumors of low malignant potential. (medicalnewstoday.com)
  • Ovarian cancer describes cancer in women that begins in the different cells of the ovaries (they produce eggs), fallopian tubes or peritoneum, which determines the type of ovarian cancer. (uchealth.org)
  • Primary malignant tumors are the most frequent type of ovarian tumors and their age incidence ranges from the third to the eighth decade. (metin2kiss.ro)
  • The presence of Müllerian lesions beyond the direct derivatives of the Müllerian ducts, primarily in the ovary and pelvic peritoneum, is ascribed to the existence of a "secondary Müllerian system"[ 3 ]. (biomedcentral.com)
  • Stage II - Growth of the cancer involves one or both ovaries with pelvic extension. (news-medical.net)
  • Your doctor will take your medical history, and will likely do a pelvic exam to check for an enlarged ovary or signs of fluid in the abdomen. (uchealth.org)
  • A thin, lighted tube through which your doctor can look at your ovaries and other pelvic organs and tissues in the area. (uchealth.org)
  • Grossly, benign Brenner tumors are small (typically less than 2 cm) and unilateral. (cap.org)
  • Mean age at diagnosis is in the early 6th decade, and most tumors are unilateral. (cap.org)
  • For women of childbearing age, simple unilateral oophorectomy via laparoscopy or laparotomy is adequate, provided that the contralateral ovary appears grossly normal. (medscape.com)
  • People who want to have children may have a unilateral salpingo-oophorectomy , which involves removing the affected ovary and its adjoining fallopian tube. (medicalnewstoday.com)
  • TCCs of the ovary are usually unilateral and average approximately 10 cm in diameter. (surgpath4u.com)
  • Borderline Brenner tumor is usually unilateral and range from 8 to 30 cm in diameter (larger than the benign counterpart). (surgpath4u.com)
  • The gonads present may be bilateral ovotestes, or they may be a combination of a unilateral ovary or testis with an ovotestis on the contralateral side. (medscape.com)
  • By definition, serous tumors are characterized by a proliferation of epithelium resembling that lining the fallopian tubes. (medscape.com)
  • Ovarian epithelial tumors are subclassified into several categories based on two criteria: 1) the degree of epithelial proliferation and invasion and 2) the histotype of the epithelium composing the tumor. (biomedcentral.com)
  • Epithelial neoplasms of the ovary are thought to arise either directly or indirectly from the ovarian surface epithelium according to incessant ovulation theory[ 4 ]. (biomedcentral.com)
  • Papillary proliferations of transitional-cell type epithelium projecting into cystic lumens are typical of borderline Brenner tumor. (surgpath4u.com)
  • In terms of origin of ovarian cancer, many of researchers and gynecologic oncologists have traditionally understood that the various different ovarian tumors are all derived from the ovarian surface epithelium (mesothelium) and that subsequent metaplastic changes lead to the development of the different cell types (Table 2 ). (biomedcentral.com)
  • The term "ovarian cancer" is often used to describe cancers that begin in the cells in the ovary, fallopian tube, or peritoneum. (cancer.net)
  • Because the surfaces of the ovaries, the lining of the fallopian tubes, and the covering cells of the peritoneum are made up of the same types of cells, most of these diseases look alike under a microscope. (cancer.net)
  • Rarely, peritoneal cancer can develop after ovaries and fallopian tubes have been removed. (cancer.net)
  • According to the National Cancer Institute (NCI), around 75% of borderline ovarian tumors are stage 1 at the point of diagnosis, meaning tumors are confined to the ovaries or fallopian tubes. (medicalnewstoday.com)
  • If a person does not wish to have children, doctors may recommend a bilateral salpingo-oophorectomy, in which a surgeon removes both ovaries and fallopian tubes. (medicalnewstoday.com)
  • A hysterectomy may also entail the removal of other organs, such as the cervix, ovaries, and fallopian tubes. (medicalnewstoday.com)
  • Recent research in women with ovarian cancer shows that cancer actually starts in the fallopian tubes and spreads to the surface of the ovaries and beyond. (uchealth.org)
  • Most of the tumors are believed to form on the surface of the ovaries, although there is some evidence indicating that they can also form on the fallopian tubes. (knowcancer.com)
  • Type I tumors are clinically indolent and usually present at a low stage, while type II tumors exhibit papillary, grandular, and solid patterns and are highly aggressive and almost always present in advanced stage (Table 1 ). (biomedcentral.com)
  • Other GCTs include the dysgerminoma and yolk sac tumor. (proprofs.com)
  • This makes diagnosis difficult until the tumor is already in advanced stages. (knowcancer.com)
  • Surgery and a biopsy of the cells is necessary for a specific and confirmed diagnosis of ovarian tumors. (knowcancer.com)
  • Some authors propose that these tumors be subclassified into 'proliferative' or 'low malignant potential' based on the amount of cytologic atypia. (surgpath4u.com)
  • In his textbook, Fletcher prefers to employ the term borderline Brenner tumors to encompass both entities and add the qualifier 'low-grade' for proliferative-type tumors and 'high-grade' for tumors with more atypical features. (surgpath4u.com)
  • Carcinoid , or well-differentiated neuroendocrine tumor, of the ovary is uncommon but may occur as a monodermal teratoma or a somatic-type malignancy arising from a teratoma or dermoid cyst. (cap.org)
  • Neoplasms of the ovary occur infrequently but when they do, they usually are painless and are found only on routine examination. (wdxcyber.com)
  • Approximately two-thirds of ovarian tumors occur in women during reproductive age, whereas less than 5% occur in children. (biomedcentral.com)
  • 60% of these tumors occur in females under the age of 40. (biomedcentral.com)
  • Borderline and malignant Brenner tumors occur in women who are approximately 10 years older. (surgpath4u.com)
  • In general, type I tumors are genetically more stable than type II tumors and display a distinctive pattern of mutations that occur in specific cell types. (biomedcentral.com)
  • Two third of ovarian tumors occur in women cancer de piele obraz reproductive age sarcoma cancer by age 1. (metin2kiss.ro)
  • Sarcoma cancer by age, Warts on hands disappear Borderline tumors occur at slightly older ages and malignant tumors are more common in women between 45 and 65 years old 2. (metin2kiss.ro)
  • Interestingly, ovaries occur more commonly on the left side than the right. (medscape.com)
  • Unfortunately the prognosis for those diagnosed with ovarian tumors is generally poor. (knowcancer.com)
  • We sarcoma cancer follow up 58 cases registered in the Pathology Sarcoma cancer follow up as oophorectomy or hysterectomy specimens diagnosed with ovarian tumors, including benign, borderline and malignant tumors of various histological types. (metin2kiss.ro)
  • The majority of secondary ovarian tumors are of endometrial origin. (metin2kiss.ro)
  • Brenner tumors are commonly associated with other ovarian neoplasms, including mucinous-type tumors. (cap.org)
  • Histologically, these tumors resemble non-invasive, low-grade urothelial neoplasms. (cap.org)
  • Epithelial cystic tumors account for about 60% of all true ovarian neoplasms. (medscape.com)
  • Mucinous epithelial tumors account for approximately 10-15% of all epithelial ovarian neoplasms. (medscape.com)
  • Initially classified as the Brenner family of ovarian tumors, these neoplasms have well-defined benign and malignant counterparts. (ijhi.org)
  • Ovarian tumors account for a considerable proportion of clinically relevant neoplasms in females, exhibiting a wide range of age at presentation (from infant to elderly patients). (biomedcentral.com)
  • They represent 30% of all epithelial tumors and 80%-85% of all ovarian cancers. (biomedcentral.com)
  • In other words, it helps halt tumor growth by stopping DNA repair in various cancers. (sciencedaily.com)
  • Borderline ovarian tumors represent 10-20% of epithelial ovarian neoplasm's [ 5 ] with an incidence of 1.8-4.8 out of 100.000 women per year [ 6 ] and typically have an excellent prognosis. (intechopen.com)
  • Borderline ovarian tumors (BOTs) are abnormal cells or growths that develop in the tissue encapsulating an ovary. (medicalnewstoday.com)
  • Can borderline ovarian tumors spread? (medicalnewstoday.com)
  • Borderline ovarian tumors that have advanced beyond stage 1 can grow in size and spread to nearby tissues and lymph nodes , as well as distant areas of the body. (medicalnewstoday.com)
  • An ovarian cyst is an abnormal growth of tissue that forms on the surface of the ovary and includes fluid. (cancer.net)
  • Epithelial ovarian tumors develop from the cells that cover the outer surface of the ovary. (news-medical.net)
  • There is no cancer on the outer surface of the ovary. (news-medical.net)
  • Studies have shown that epithelial ovarian cancer is not a single disease but is composed of a diverse group of tumors that can be classified based on distinctive morphologic and molecular genetic features [ 1 ]. (biomedcentral.com)
  • There was extensive necrosis of the tumor with few viable areas. (ijhi.org)
  • In contrast, the above case of higher grade borderline tumor exhibits more prominent nuclear atypia as well as high mitotic activity and areas of necrosis. (surgpath4u.com)
  • Characterized byvtche presence of tumor necrosis, cytologic atypia and mitotic activity. (brainscape.com)
  • however, recurrent tumors arise when AR is reactivated, a common occurrence in the castrate-resistant stage of the disease. (sciencedaily.com)
  • These tumours do better than other types of epithelial tumours of the ovary. (wikipedia.org)
  • Purpose: Small bowel adenocarcinoma (SBA) is a rare tumor of the gastrointestinal system with poor prognosis. (medipol.edu.tr)
  • Tumor Metrics And Morphology Predict Poor Prognosis In Prenatally Diagnosed. (keyopinionleaders.com)
  • It is a high-grade and poorly differentiated neuroendocrine tumor, usually diagnosed in advanced stages, with a poor prognosis and few therapeutic options in that setting. (mdpi.com)
  • In the case of a malignant tumor, it may spread to surroundings area including colon and lung 4 . (syndromespedia.com)
  • Borderline tumors are characterized by cell proliferation and a minor degree of nuclear atypia without stromal invasion. (biomedcentral.com)
  • Produces a "barrel cervix" if the tumor encircles the cervix and invades the underlying stroma. (brainscape.com)
  • 40% more new cancer patients annu- are breast, colorectum, cervix, ovary Even in the highest income countries ally by 2025. (who.int)
  • Blumenfeld Z, Kerner H, Thaler I, Deutsch M, Beck D: Increased alpha fetoprotein levels in mixed mesodermal tumors of ovary. (sapub.org)
  • More pronounced nuclear atypia distinguishes low-grade from high-grade borderline tumors. (surgpath4u.com)
  • Grossly, borderline Brenner tumors are cystic and unilocular or multilocular. (surgpath4u.com)
  • Primordial follicles of adult ovaries did not contain STAR, whereas antral follicles stained intensely in the thecal layer, with occasional staining of granulosa cells. (elsevierpure.com)
  • An ovarian Leydig cell tumor stained intensely, whereas granulosa cell tumors were negative. (elsevierpure.com)
  • TCCs and Brenner tumors share transitional cell type morphology only, but TCCs do not exhibit true urothelial differentiation. (surgpath4u.com)
  • The benign Brenner tumor (BT) is easily diagnosed owing to its classic morphology. (ijhi.org)
  • Extensive sampling of both the ovarian masses revealed tumors with similar morphology. (ijhi.org)
  • Based on their tumoral behavior, we had: three cases of benign tumors, all of them associated with a different histological tumor type and grade in the contralateral ovary, 12 cases of borderline tumors and 46 cases sarcoma cancer by age sarcoma cancer follow up tumors 39 cases of primary and 7 cases of secondary tumors. (metin2kiss.ro)
  • Microscopically, the tumors are composed of solid to cystic nests of epithelial cells embedded in a fibrous stroma. (cap.org)
  • 2) This less common pattern is called 'Brenner-type', consisting of nests and cords of malignant transitional cells invading the fibrous ovarian stroma. (surgpath4u.com)
  • there were marked nuclear pleomorphism and brisk mitotic activity [Figure 1] C. In the sections from the right ovary, there were two foci showing nests of mildly atypical cells embedded in a fibrous stroma [Figure 1] D and E. The morphological possibilities considered were a malignant BT versus a TCC of the ovary. (ijhi.org)
  • Brenner tumor is a rare ovarian tumor which is usually benign, but rarely, it may be malignant. (bvsalud.org)
  • BOTs are noninvasive abnormal cells or growths that form in the tissue covering the ovaries. (medicalnewstoday.com)
  • If an ovary is not distinctly seen on an imaging study but there is a mixed cystic and solid mass in the adnexal region, it is most likely to be a benign lesion. (wdxcyber.com)