AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and Equipment
Pseudomyxoma PeritoneiPeritoneal NeoplasmsAppendiceal NeoplasmsMucoceleAppendixMucin-2Adenocarcinoma, MucinousCystadenoma, MucinousHyperthermia, InducedMucin 5ACChemotherapy, Cancer, Regional PerfusionMucinsOvarian NeoplasmsAppendectomyMitomycinNeoplasms, Multiple PrimaryPeritoneum
CystsNeoplasmsAppendiceal CancerMalignanciesBorderlineBenignHistologyCancerPeritoneal mesotheliomaCarcinomasMultilocularAppendixMucinous adenocarcinomaPatientsCavityCancersRuptureAscitesOvaryUrinary frequencyEpithelial cellsAcuteUltrasoundDiagnosisProliferationClinicalCarcinoidInsulinomaInvasiveCytoreductionMetastasesChemotherapy solutionArteryUretersAdnexalAbnormalHysterectomyPelvicLiverGastrointestinalNausea
Cysts13
  • Most patients with ovarian cysts are asymptomatic, with the cysts being discovered incidentally during ultrasonography or routine pelvic examination. (medscape.com)
  • The definitive diagnosis of all ovarian cysts is made based on histologic analysis. (medscape.com)
  • Laboratory tests, although not diagnostic for ovarian cysts, may aid in the differential diagnosis of cysts and in the diagnosis of cyst-related complications. (medscape.com)
  • Many patients with simple ovarian cysts found through ultrasonographic examination do not require treatment. (medscape.com)
  • Oral contraceptive pills (OCPs) protect against the development of functional ovarian cysts. (medscape.com)
  • Persistent simple ovarian cysts larger than 10 cm (especially if symptomatic) and complex ovarian cysts should be considered for surgical removal. (medscape.com)
  • Bilateral oophorectomy and, often, hysterectomy are performed in many postmenopausal women with ovarian cysts, because of the increased incidence of neoplasms in this population. (medscape.com)
  • A 2-year interim analysis from the International Ovarian Tumor Analysis Phase 5 (IOTA5) study showed that 80% of ovarian cysts considered benign on ultrasonography either disappeared or required no intervention. (medscape.com)
  • A systematic review and meta-analysis by Liu et al found that the malignancy rate, including borderline tumors, for simple ovarian cysts in postmenopausal women was approximately 1 in 10,000. (medscape.com)
  • The utility of ultrasound elastography in differentiation of endometriomas and hemorrhagic ovarian cysts. (endometriosi.it)
  • To investigate the feasibility of acoustic radiation force impulse imaging in differentiation of endometriomas and hemorrhagic ovarian cysts. (endometriosi.it)
  • We evaluated 84 ovarian cysts with high internal echogenicity diagnosed in 70 consecutive women. (endometriosi.it)
  • We obtained the elastographic shear wave velocity (SWV) value of the cysts that could be endometriomas or hemorrhagic ovarian cysts. (endometriosi.it)
Neoplasms3
Appendiceal Cancer4
  • Promoting Awareness of PMP (Pseudomyxoma Peritonei), Appendiceal Cancer and other Peritoneal Surface Malignancies. (cancerindex.org)
  • Cancer that has spread to the lining surfaces of the peritoneal (abdominal) cavity from ovarian cancer, primary colorectal cancer, appendiceal cancer, or mesothelioma and pseudomyxoma peritonei-known as peritoneal carcinomatosis-are cancers that are frequently referred to as peritoneal cancers. (cedars-sinai.org)
  • The peritoneum is more often involved by cancer cells that have spilled from tumors originating elsewhere for example from advanced ovarian cancer, colorectal cancer, appendiceal cancer, gastric cancer, pancreatic cancer, gall bladder cancer etc. (thangamcancercenter.com)
  • Peirtoneal spread or metastases is however, commonly seen in cases of advnaced ovarian cancer, colorectal cancer, gastric cancer and appendiceal cancer. (thangamcancercenter.com)
Malignancies4
  • A charitable organization founded in 2008 by a community of individuals affected by Pseudomyxoma Peritonei (PMP) and related Peritoneal Surface Malignancies (PSM). (cancerindex.org)
  • An increasing number of patients are presenting with peritoneal carcinomatosis, or widespread metastasis of the peritoneum, which can result from a variety of tumors, including digestive and gynecologic malignancies. (oncnursingnews.com)
  • Peritoneal surface malignancies comprises of tumors originating in the peritoneal lining of the abdomen (known as primary peritoneal cancers) as well as tumors that have spread from their primaty site of origin to the peritoneaum (peritoneal metastases). (thangamcancercenter.com)
  • Cytoreductive surgery (CRS) and heated intraperitoneal chemotherapy (HIPEC) have become accepted treatments for limited-volume peritoneal disease in appendiceal, ovarian, and colorectal malignancies, but there are limitations. (stanford.edu)
Borderline7
  • A borderline tumor, sometimes called low malignant potential (LMP) tumor, is a distinct but yet heterogeneous group of tumors defined by their histopathology as atypical epithelial proliferation without stromal invasion. (wikipedia.org)
  • It generally refers to such tumors in the ovary (generally specifically called borderline ovarian tumors (BOT)) but borderline tumors may rarely occur at other locations as well. (wikipedia.org)
  • Borderline ovarian tumours differ from epithelial ovarian cancer by their low incidence, frequent association with infertility, low association with mutations in BCRA genes, different percentages of the most common histological types, early stage diagnosis, and high survival rate, even when associated with peritoneal involvement. (wikipedia.org)
  • Borderline ovarian tumours (BOTs) have been qualified as low malignant potential tumours by the FIGO since 1971. (wikipedia.org)
  • subsequently, this group of tumors of the ovary were classified in 1973 by the World Health Organization as "low malignant potential ovarian tumor" [ 2 ] and, finally, in 2003 WHO separates them from carcinomas and call them borderline tumors. (intechopen.com)
  • Borderline ovarian tumors represent 10-20% of epithelial ovarian neoplasm's [ 5 ] with an incidence of 1.8-4.8 out of 100.000 women per year [ 6 ] and typically have an excellent prognosis. (intechopen.com)
  • Unlike the invasive carcinomas, borderline ovarian tumors are characterized by cytoplasmic and nuclear atypia, (element of differential diagnosis with benign tumors), absence of stromal invasion, (element of differential diagnosis with malignant tumors), unusual degree of proliferation of the epithelial cells with cellular stratification including remarkable architectural atypia and the formation of papillary protuberances. (intechopen.com)
Benign4
  • Although the discovery of an ovarian cyst causes considerable anxiety in women owing to fears of malignancy, the vast majority of these lesions are benign. (medscape.com)
  • One third of all ovarian tumors are serous, and two thirds of these serous tumors are benign. (medscape.com)
  • Of these tumors, 75% are benign and are found in women aged 30-50 years. (medscape.com)
  • The ovaries consist of different types of tissue ( epithelial , germ cells, and sex cord tissue), which may give rise to benign or malignant tumors . (amboss.com)
Histology2
  • Peritoneal implants are very uncommon (15%), and when they occur, a mixed histology as well as the presence of pseudomyxoma peritonei must be ruled out. (wikipedia.org)
  • According to Bassel El-Rayes, MD, director, Gastrointestinal Oncology Translational Research Program, Winship Cancer Institute, three key factors must be considered when making the determination: origin of the tumor, extent of disease, and tumor histology. (oncnursingnews.com)
Cancer16
  • Newer markers for ovarian cancer are on the horizon. (medscape.com)
  • In women desiring future fertility who have stage IA low-risk ovarian cancer, conservative surgical therapy is appropriate, provided that close follow-up can be maintained. (medscape.com)
  • The site includes information about the types of appendix cancer, treatment, survivors' stories, FAQ. (cancerindex.org)
  • Complications of peritoneal cancer may include bowel obstructions (sometimes necessitating a stoma, or hole between the intestine and the outside of the body), and urinary tract obstruction (due to blockage of the ureters by tumors), sometimes requiring a stent or nephrostomy tube (a tube from the kidney to the outside of the body). (cedars-sinai.org)
  • Checking your tumor markers, which are blood tests that may be elevated when patients have this type of cancer, can also be helpful. (cedars-sinai.org)
  • Fluid in the abdominal cavity also can be sampled to look for the presence of cancer cells. (cedars-sinai.org)
  • These include tumors of the appendix and pseudomyxoma peritonei, mesothelioma, and selected cases of ovarian, colorectal and gastric cancer. (bvsalud.org)
  • Her family history included bowel, prostate, and breast cancer. (amsj.org)
  • These are common tumour markers used in conjunction with clinical examination and other investigations to aid cancer diagnosis. (amsj.org)
  • With more than 150 top cancer specialists serving the needs of our patients, Massey's health care team provides a wealth of expertise in cancer diagnosis, treatment, prevention and symptom management. (masseycancercenter.org)
  • According to Sanjay S. Reddy, MD, a surgical oncologist at Fox Chase Cancer Center, it began back in the 1970s with the use of intraperitoneal chemotherapy for the treatment of ovarian cancer. (oncnursingnews.com)
  • These include, long term use of oral contraceptive pills, use of hormone replacement therapy, use of tamoxifen in breast cancer patients and estrogen producing ovarian tumors. (thangamcancercenter.com)
  • The aim was to develop a comprehensive scale that comprises all features of gynecologic cancer survivors` requirements in Iranian population.Materials & Methods: The Cancer Survivors Assessment Questionnaire NCCN2.2020 (National comprehensive cancer network) was translated including the instructions, and the answer choices by two native translators, including one fluent translator and one linguist. (jogcr.com)
  • Tumors or cancer of the LIVER. (lookformedical.com)
  • Tumors or cancer of the PANCREAS. (lookformedical.com)
  • Tumors or cancer of the SKIN. (lookformedical.com)
Peritoneal mesothelioma2
  • There is substantial clinical evidence that HIPEC is an effective treatment for patients with pseudomyxoma peritonei, mucinous adenocarcinoma of the appendix and peritoneal mesothelioma. (cedars-sinai.org)
  • Tumors originating in the peritoneum itself are rare and include malignant peritoneal mesothelioma, primary peritoneal serous carcinoma, Leiomyomatosis peritonealis disseminata, Desmoplastic small round cell tumor etc. (thangamcancercenter.com)
Carcinomas1
  • Mucinous BOT constitutes between 32% and 42% of the total (compared with less than 10% of mucinous ovarian carcinomas). (wikipedia.org)
Multilocular2
  • A multilocular right ovarian cyst that is 24 cm in diameter. (medscape.com)
  • The tumors are generally multilocular, and the mucus-containing loculi appear blue through the tense capsules. (medscape.com)
Appendix2
  • About two thirds of appendix tumours are carcinoid tumours which develop in hormone-producing cells that are present in many parts of the body, including the appendix. (cancerindex.org)
  • Less common tumours of the appendix include signet-ring cell adenocarcinoma and paraganglioma . (cancerindex.org)
Mucinous adenocarcinoma1
  • Pseudomyxoma Peritonei ( PMP ) is a more common name given to the "jelly belly" syndrome caused by mucinous adenoma and mucinous adenocarcinoma. (cancerindex.org)
Patients9
  • patients often present with ovarian torsion. (medscape.com)
  • Cohorts of patients who were diagnosed with UA and an AN were included in the study. (cancerindex.org)
  • Patients in the early stages of the disease will often have few symptoms until the disease is fairly advanced. (cedars-sinai.org)
  • Imaging studies are helpful in evaluating patients who have symptoms suggestive of peritoneal carcinomatosis. (cedars-sinai.org)
  • METHOD: In this retrospective study, we included 79 patients admitted to Semmelweis University Department of Surgery, Transplantation and Gastroenterology between October 2020 and September 2022. (bvsalud.org)
  • The clinical implications of this are that PMP is not commonly considered a differential diagnosis in patients with these symptoms, which may then delay the diagnosis being made. (amsj.org)
  • HIPEC (heated intraperitoneal chemotherapy) is a complex procedure reserved for patients with advanced abdominal cancers. (masseycancercenter.org)
  • 1 The diagnosis is devastating, with treatment often limited to palliation of symptoms, but a combination of cytoreductive surgical resection (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC)-sometimes referred to as "hot chemotherapy bath"—has the potential to provide some patients with long-term survival. (oncnursingnews.com)
  • Patients with tumors that are aggressive or have metastasized are not good candidates for this treatment, regardless of where their tumor originated," said El-Rayes. (oncnursingnews.com)
Cavity6
  • PET-CT can also be done to determine if disease has spread outside the abdominal cavity, such as the lungs. (cedars-sinai.org)
  • HIPEC is essentially a chemotherapy 'bath' that delivers heated chemotherapy directly into the abdominal cavity, where it penetrates the diseased tissue directly. (cedars-sinai.org)
  • It involves cytoreduction surgery to remove as much of the tumor or tumors as possible, followed by the circulation of a heated chemotherapy solution throughout the abdominal cavity. (masseycancercenter.org)
  • The selected agent is heated before it is infused into the abdominal cavity. (oncnursingnews.com)
  • Peritoneum is a thin membrane which forms the lining of the abdominal cavity as well as covers most of the intra-abdominal organs. (thangamcancercenter.com)
  • Peritoneum also plays an important role in transfer of fluids and solutes from the abdominal (peritoneal) cavity to the blood. (thangamcancercenter.com)
Cancers4
  • This technique, which combines surgery with chemotherapy, has revolutionized the treatment of cancers in the abdominal (peritoneal) lining that stem from colon, gastric, ovarian and appendiceal cancers, as well as mesothelioma and pseudomyxoma peritonei. (cedars-sinai.org)
  • There is substantial evidence showing HIPEC is an effective treatment for several cancers affecting the abdominal region. (masseycancercenter.org)
  • Almost all cancers originatig in intra-abdominal organs can spread to the peritoneum in advanced stages. (thangamcancercenter.com)
  • Tumors or cancers of the KIDNEY. (lookformedical.com)
Rupture3
  • The tumors result from either failure of a dominant mature follicle to rupture or failure of an immature follicle to undergo the normal process of atresia. (medscape.com)
  • The larger varieties are associated with an increased risk of rupture, with resultant pseudomyxoma peritonei. (medscape.com)
  • Rupture of a mucinous cystadenoma or cystadenocarcinoma leading to the spread of tumor cells throughout the peritoneum . (amboss.com)
Ascites3
  • A large cyst may be palpable on abdominal examination, but gross ascites may interfere with palpation of an intra-abdominal mass. (medscape.com)
  • On physical examination, your surgeon can sometimes feel tumor nodules in the abdomen or fluid (ascites). (cedars-sinai.org)
  • Pseudomyxoma peritonei (PMP) is a rare, slow growing mucinous ascites, typically associated with primary appendiceal or ovarian neoplasm [1]. (amsj.org)
Ovary1
  • An ovarian cyst is a sac filled with liquid or semiliquid material that arises in an ovary (see the image below). (medscape.com)
Urinary frequency1
  • When symptoms occur, they are often vague and nonspecific, with symptoms of abdominal swelling, diffuse abdominal pain, urinary frequency and a sense of fullness when eating. (cedars-sinai.org)
Epithelial cells1
  • It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
Acute2
  • The diagnosis is often made based on clinical signs and symptoms of acute appendicitis or coincidentally via imaging methods when it is asymptomatic. (acquaintpublications.com)
  • Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C. (lookformedical.com)
Ultrasound1
  • Typical conditions diagnosed by gastroscopy, colonoscopy and abdominal ultrasound were gastroesophageal reflux disease (11/26), irritable bowel syndrome (2/19) and diffuse hepatic lesions, respectively. (bvsalud.org)
Diagnosis3
  • Laparoscopy is a minimally invasive procedure where, through small incisions, samples of tumor (biopsies) are removed and sent to pathology to confirm a diagnosis. (cedars-sinai.org)
  • The symptoms of PMP are often non-specific and vague, causing difficulties in diagnosis. (amsj.org)
  • However, it may rarely receive a definitive diagnosis before surgery despite all technical possibilities, and it may be encountered during abdominal surgery performed for another indication. (acquaintpublications.com)
Proliferation1
  • By definition, serous tumors are characterized by a proliferation of epithelium resembling that lining the fallopian tubes. (medscape.com)
Clinical2
  • A questionnaire including demographic and clinical information, MRI, and pathology reports were collected from participants. (jogcr.com)
  • The predictive value of clinical symptoms is weak compared to MRI. (jogcr.com)
Carcinoid1
  • Mucocele may also develop when the lumen is obstructed due to endometriosis or carcinoid tumors. (acquaintpublications.com)
Insulinoma1
Invasive1
  • The surgical approaches include an open technique (laparotomy) or a minimally invasive technique (laparoscopy) with very small incisions. (medscape.com)
Cytoreduction1
  • Depending on your tumor type, you may be a candidate for surgery to remove all of the tumor, known as cytoreduction, and followed by HIPEC. (cedars-sinai.org)
Metastases1
  • The peritoneum is a common site of metastases for gastrointestinal tumors that predicts a poor outcome. (stanford.edu)
Chemotherapy solution1
  • This targeted contact of the heated drug kills the tumor nodules, which increases absorption of the chemotherapy solution. (cedars-sinai.org)
Artery2
  • The infundibulo-pelvic ligament carrying the ovarian artery and vein has been divided. (medscape.com)
  • In both procedures, chemotherapy is injected into the hepatic (liver) artery that supplies the liver tumor. (cancerhealthcenter.com)
Ureters1
  • Female urinary system Your urinary system - which includes the kidneys, ureters, bladder and urethra - is responsible for removing waste from your body through urine. (cancerhealthcenter.com)
Adnexal1
  • nevertheless, when there are symptoms these are often non-specific, similar to other adnexal tumours, such as pelvic pain or abdominal distension. (wikipedia.org)
Abnormal2
  • Other symptoms may include bowel changes (more frequent constipation), abnormal vaginal bleeding, an abdominal mass or unintended weight loss. (cedars-sinai.org)
  • OBJECTIVE: We aimed to identify the most common gastrointestinal symptoms, abnormal laboratory findings and risk factors relevant to post-COVID syndrome. (bvsalud.org)
Hysterectomy1
  • The patient was discussed at the multidisciplinary team meeting where it was recommended that she undergo a laparotomy for total abdominal hysterectomy, bilateral salpingo-oophrectomy, and omentectomy. (amsj.org)
Pelvic2
  • In addition, in advanced stages, these may be associated with lymphatic involvement in about 27% of cases, including the following in descending order of frequency: pelvic, omental and mesenteric, and paraaortic and supradiaphragmatic regions. (wikipedia.org)
  • Conclusion: right-sided pelvic lesion consistent with ovarian mucinous cystadenomatous-type lesion. (amsj.org)
Liver1
Gastrointestinal1
  • Vaccinated status may prevent post-COVID gastrointestinal symptoms. (bvsalud.org)
Nausea3
  • As the disease progresses, fluid may build up in the abdomen, causing abdominal discomfort, nausea and vomiting, and shortness of breath. (cedars-sinai.org)
  • Importantly, she had not been unwell, did not have any infective symptoms, no loss of weight or appetite, and no nausea or vomiting. (amsj.org)
  • Other symptoms include nausea, vomiting and change in bowel habits [6] . (acquaintpublications.com)