• The most frequently encountered neoplastic pancreatic cysts include intraductal papillary mucinous neoplasm (IPMN), serous cystadenoma (SCA), mucinous cystic neoplasm with ovarian stroma (MCN), and solid pseudopapillary epithelial neoplasm. (medscape.com)
  • In contrast to some of the other cyst-forming tumors of the pancreas (such as the intraductal papillary mucinous neoplasm and the pancreatic mucinous cystadenoma), serous cystic neoplasms are almost always entirely benign. (wikipedia.org)
  • Appendiceal mucocele is a descriptive term referring to distention of the appendix with mucus, which develops secondary to mucinous cystadenoma (63 %), mucosal hyperplasia (25 %), mucinous cystadenocarcinoma (11 %) and retention cysts (1 %) of the appendix lumen [1] . (acquaintpublications.com)
  • After albendazole therapy was initiated, a laparotomy was performed and a huge ovarian cystadenoma was diagnosed. (biomedcentral.com)
  • Mucinous cystic neoplasms of the pancreas with overt and latent malignancy (cystadenocarcinoma and cystadenoma): a clinicopathologic study of 41 cases. (unina.it)
  • Rupture of a mucinous cystadenoma or cystadenocarcinoma leading to the spread of tumor cells throughout the peritoneum . (amboss.com)
  • In the present report, we describe a rare case of primary signet ring cell carcinoma of the appendix with ovarian metastasesand unresectable peritoneal dissemination occurring in a 45-year-old female patient. (wjgnet.com)
  • To study the relationship between carcinoembryonic antigen (CEA) level, intraductal papillary mucinous neoplasm (IPMN) subtype, and the presence of invasive carcinoma. (gastrores.org)
  • However, there was no correlation between CEA level and cystic mucinous secretions or mucinous epithelial cytoplasm CEA staining, mucin glycoprotein expression, size of lesion, grade of dysplasia or presence of invasive carcinoma. (gastrores.org)
  • In addition to CEA being used to stratify mucinous vs. non-mucinous lesions, several studies have attempted to correlate pancreatic cyst fluid CEA level and the presence of invasive carcinoma, with discordant results [ 17 , 18 ]. (gastrores.org)
  • However, as explained below, recent morphologic findings and molecular analyses have demonstrated that each morphologic subtype of ovarian carcinoma might be derived from a Müllerian-type epithelium. (biomedcentral.com)
  • The purpose of this case-control study was to compare the prognoses of women with stage III mucinous ovarian carcinoma (MOC) who received maximal or optimal cytoreduction followed by paclitaxel plus carboplatin chemotherapy to those of women with stage III serous epithelial ovarian cancer (EOC) treated in the similar manner. (biomedcentral.com)
  • Mucinous breast carcinoma with tall columnar cells. (nih.gov)
  • Mucinous metaplasia of breast carcinoma with macrocystic transformation resembling ovarian mucinous cystadenocarcinoma in a case of synchronous bilateral infiltrating ductal carcinoma. (nih.gov)
  • To define molecular and biochemical profiles associated with the duration of progression-free survival in platinum-sensitive recurrent ovarian, peritoneal primary or fallopian tube carcinoma treated with combination chemotherapy with or without bevacizumab followed with or without maintenance bevacizumab therapy in the presence or absence of secondary surgical cytoreduction. (ucsf.edu)
  • The tumors may be entirely benign, as are mucinous cystadenomas or intraductal papillary mucinous adenomas. (medscape.com)
  • Objective We aim to determine the most accurate cyst carcinoembryonic antigen cut-off value for distinguishing mucinous cysts from non-mucinous cysts with a focus on discriminating intraductal papillary mucinous neoplasms. (unina.it)
  • Conclusions Pancreatic cyst fluid carcinoembryonic antigen can accurately differentiate histologically verified mucinous lesions, including intraductal papillary mucinous neoplasms, from non-mucinous lesions with an optimal cut-off that is much lower than previously reported values. (unina.it)
  • International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas. (unina.it)
  • Intraductal papillary mucinous neoplasm (IPMN) is a substantial subclass of pancreatic pathology, representing 20-50% of cystic pancreatic neoplasms [ 1 - 3 ]. (gastrores.org)
  • A benign, intermediate, or malignant neoplasm characterized by the formation of papillary structures. (nih.gov)
  • Pathology of intraductal papillary mucinous neoplasms. (nih.gov)
  • The Clinical and Pathologic Features of Intracholecystic Papillary-Tubular Neoplasms of the Gallbladder. (nih.gov)
  • [ 5 ] Other, rarer cystic lesions, such as solid pseudopapillary epithelial neoplasm and cystic pancreatic neuroendocrine tumor (cPNET), tend to harbor features that suggest a specific diagnosis, usually leading to surgical removal. (medscape.com)
  • The purpose of this report is to describe the features of angiosarcoma arising in mucinous tumor that was misinterpreted as a benign vascular proliferation during the intraoperative consultation. (hindawi.com)
  • A 35 cm right ovarian mass submitted for intraoperative consultation was a multicystic mucinous tumor with an 8 cm area of hemorrhagic lesion between cystic locules. (hindawi.com)
  • The frozen section diagnosis was at least mucinous borderline tumor. (hindawi.com)
  • A macroscopic hemorrhagic area in an ovarian mucinous tumor should be evaluated with care, and the possibility of angiosarcoma should be borne in mind. (hindawi.com)
  • Mucinous tumor is a common type of ovarian epithelial tumors. (hindawi.com)
  • The frozen section diagnosis was at least mucinous borderline tumor, pending adequate tissue sampling for permanent sections to rule out mucinous adenocarcinoma. (hindawi.com)
  • Saad B, Abdelhamid B, Moulay El Mehdi TH, Abdellah B, Kouach J (2020) Appendiceal Mucocele Simulating an Ovarian Tumor. (acquaintpublications.com)
  • Context Carcinoembryonic antigen analysis of pancreatic cyst fluid is the tumor marker of choice for preoperatively differentiating mucinous from non-mucinous cystic lesions. (unina.it)
  • It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
  • Epithelial ovarian tumors are the most common tumor subtype. (amboss.com)
  • Approximately 5% of mucinous cystadenomas are associated with a dermoid cyst or a Brenner tumor. (surgpath4u.com)
  • Ovarian tumors comprise a heterogeneous group of lesions, displaying distinct tumor pathology and oncogenic potentiel. (biomedcentral.com)
  • According to the 2014 World Health Organization (WHO) classification and tumor morphology, primary ovarian tumors are subdivided into three categories: epithelial (60%), germ cell (30%), and sex-cord stromal tumors (8%)[ 1 ]. (biomedcentral.com)
  • Ovarian epithelial tumors are subclassified into several categories based on two criteria: 1) the degree of epithelial proliferation and invasion and 2) the histotype of the epithelium composing the tumor. (biomedcentral.com)
  • We wondered whether the worse prognosis associated with mucinous histology is also valid when age, tumor grade, substage of disease, and extent of RD are matched with serous histology in women with stage III EOC who have undergone primary CRS followed by standard intravenous paclitaxel plus carboplatin chemotherapy. (biomedcentral.com)
  • Through genetic studies of exome sequence, it was found that gliomatosis is genetically identical to the parent ovarian tumor and developed from cells that disseminate from the ovarian teratoma. (mdwiki.org)
  • Spatial Transcriptomics Depict Ligand-Receptor Cross-talk Heterogeneity at the Tumor-Stroma Interface in Long-Term Ovarian Cancer Survivors. (viictr.org)
  • Comparative Tumor Microenvironment Analysis of Primary and Recurrent Ovarian Granulosa Cell Tumors. (viictr.org)
  • Invasive mucinous adenocarcinoma is uncommon and usually arises in the background of benign or borderline tumors. (hindawi.com)
  • Pseudomyxoma Peritonei ( PMP ) is a more common name given to the "jelly belly" syndrome caused by mucinous adenoma and mucinous adenocarcinoma. (cancerindex.org)
  • women with mixed histologies including mucinous tumors combined with endometrioid, serous, clear-cell, and/or other histologic types were excluded. (biomedcentral.com)
  • Malignancy occurs only in mucinous cysts. (medscape.com)
  • Both tubal structures (hydrosalpinx, hydatids) and congenital broad ligament cystic masses (paramesonephric remnants) can appear to be ovarian cysts if the ovary is not seen in imaging separately on that side. (wdxcyber.com)
  • Most patients with ovarian cysts are asymptomatic, with the cysts being discovered incidentally during ultrasonography or routine pelvic examination. (medscape.com)
  • The definitive diagnosis of all ovarian cysts is made based on histologic analysis. (medscape.com)
  • Laboratory tests, although not diagnostic for ovarian cysts, can aid in the differential diagnosis of cysts and in the diagnosis of cyst-related complications. (medscape.com)
  • Many patients with simple ovarian cysts found through ultrasonographic examination do not require treatment. (medscape.com)
  • Oral contraceptive pills (OCPs) protect against the development of functional ovarian cysts. (medscape.com)
  • Persistent simple ovarian cysts larger than 5-10 cm (especially if symptomatic) and complex ovarian cysts should be considered for surgical removal. (medscape.com)
  • Sensitivity and specificity curves of cyst fluid CEA levels for differentiating mucinous from non-mucinous cysts. (unina.it)
  • During the diagnostic workup for pancreatic cysts, CEA is often utilized to distinguish those pancreatic cystic lesions that are likely to be mucinous [ 13 - 16 ]. (gastrores.org)
  • Mucinous cystadenomas consist of simple unilocular or multilocular cysts lined by mucinous epithelium of endocervical or intestinal types. (surgpath4u.com)
  • Other smaller cysts are lined by a columnar mucinous epithelium. (surgpath4u.com)
  • Rupture of mucinous glands and cysts often occurs during surgical removal, producing small mucin granulomas with numerous macrophages and occasional multinucleated giant cells caused by extravasation of mucinous secretions into the stroma. (surgpath4u.com)
  • Indeed, it has been postulated that the possible mechanisms by which repetitive ovulation could influence the development of ovarian carcinomas include an increased formation of inclusion cysts, repeated bathing of the surface epithelium by an estrogen-rich follicular fluid, excessive production of growth factors or cytokines, and an aberration of the repetitive repair process that follows the trauma to the surface epithelium as a consequence of ovulation. (biomedcentral.com)
  • Serous carcinomas are thought to be derived from the fallopian tubes through foci of endosalpingiosis, which are inclusion cysts from the tubal epithelium at the ovarian and peritoneal surface. (biomedcentral.com)
  • Biliary cytadenoma or mucinous cystic neoplasm of the liver is an uncommon premalignant cystic lesion, which accounts for less than 5% of all intrahepatic biliary cysts and occurs primarily in middle aged women with a peak incidence in the 50s. (drpapoulas.com)
  • Malignant cystadenocarcinoma and intramedullary mucinous carcinomas may be further subdivided into noninvasive and invasive types. (medscape.com)
  • They are divided into three categories: (1) mucinous cystadenomas or cystadenofibromas, (2) borderline mucinous tumors (also known as mucinous tumors of low malignant potential), and (3) mucinous carcinomas. (surgpath4u.com)
  • We report herein the newly described molecular abnormalities in epithelial ovarian cancers (carcinomas). (biomedcentral.com)
  • Our better understanding of the molecular basis of ovarian carcinomas represents the first step in the development of targeted therapies in the near future. (biomedcentral.com)
  • However, the vast majority of malignant ovarian tumors (80%-85%) are classified as epithelial tumors (carcinomas). (biomedcentral.com)
  • In contrast, 80%-90% of ovarian carcinomas are detected after the age of 40, and 40% of these tumors are detected after the age of 65. (biomedcentral.com)
  • Ovarian carcinomas are characterized by a Müllerian morphology although the ovaries do not originate from the Müllerian ducts. (biomedcentral.com)
  • Mucinous breast carcinomas lack PIK3CA and AKT1 mutations. (nih.gov)
  • Mucinous (so-called colloid) carcinomas of lung. (nih.gov)
  • Although the discovery of an ovarian cyst causes considerable anxiety in women owing to fears of malignancy, the vast majority of these lesions are benign. (medscape.com)
  • Methods The results of pancreatic cyst aspiration carcinoembryonic antigen levels from a single center were retrospectively collected and evaluated for a diagnosis of a mucinous cyst and an assessment of malignancy using surgical histology as the diagnostic standard in 86 patients. (unina.it)
  • The large majority of mucinous tumors are benign and borderline tumors. (hindawi.com)
  • Usually, intentinal-type epithelium is more common in borderline and malignant mucinous tumors, but can occasionally be seen in benign mucinous tumors. (surgpath4u.com)
  • Intestinal-type epithelium with goblet cells or Paneth cells are occasionally seen, but this type of epithelium is more common in borderline or malignant mucinous tumors. (surgpath4u.com)
  • The mucinous variant of columnar cell lesions. (nih.gov)
  • Angiosarcoma of the ovary is rare but represents an aggressive type of malignant ovarian neoplasms. (hindawi.com)
  • Neoplasms of the ovary occur infrequently but when they do, they usually are painless and are found only on routine examination. (wdxcyber.com)
  • Because ovarian neoplasms can show different pathologic features in the various areas of the neoplasm, the entire neoplasm is submitted for pathological examination which means removal of that entire ovary. (wdxcyber.com)
  • While it is possible that this represents a ovarian mass with mostly solid components, it is much more commonly a benign process involving the bowel, tube or adhesive disease around the ovary. (wdxcyber.com)
  • An ovarian cyst is a sac filled with liquid or semiliquid material that arises in an ovary (see the image below). (medscape.com)
  • Mucinous epithelial tumors of the ovary are characterized by epithelial cells that recapitulate endocervical epithelium or gastrointestinal epithelium. (surgpath4u.com)
  • Mucinous Tumors of the Ovary: A Review. (surgpath4u.com)
  • Epithelial neoplasms of the ovary are thought to arise either directly or indirectly from the ovarian surface epithelium according to incessant ovulation theory[ 4 ]. (biomedcentral.com)
  • Ovarian stroma of mucinous cystadenomas is often quite cellular. (surgpath4u.com)
  • Etiology Thecoma-fibroma tumors are a closely related group of benign tumors that arise from ovarian stroma and are often difficult for the imager and even pathologist to distinguish. (symptoma.com)
  • Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. (lookformedical.com)
  • A multilocular right ovarian cyst that is 24 cm in diameter. (medscape.com)
  • She was clinically misdiagnosed as torsion of ovarian cyst. (wjgnet.com)
  • Neoplasms containing cyst-like formations or producing mucin or serum. (lookformedical.com)
  • In the remaining cases, angiosarcoma was associated with ovarian teratoma or epithelial neoplasm [ 2 , 4 ]. (hindawi.com)
  • Gliomatosis peritoneii, which presents as a deposition of mature glial cells in the peritoneum, is almost exclusively seen in conjunction with cases of ovarian teratoma. (mdwiki.org)
  • [18] There also may be a cultural difference, with fetiform teratoma being reported more often in ovarian teratomas (by gynecologists) and fetus in fetu being reported more often in retroperitoneal teratomas (by general surgeons). (mdwiki.org)
  • Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer. (viictr.org)
  • Mucinous cystic tumors of the pancreas: clinicopathological features, prognosis, and relationship to other mucinous cystic tumors. (unina.it)
  • To determine if surgical secondary cytoreduction in addition to adjuvant chemotherapy increases the duration of overall survival in patients with recurrent platinum sensitive epithelial ovarian cancer , peritoneal primary or fallopian tube cancer. (ucsf.edu)
  • To determine if the addition of bevacizumab to the second-line and maintenance phases of treatment increases the duration of overall survival relative to second-line paclitaxel and carboplatin alone in patients with recurrent platinum sensitive epithelial ovarian cancer, peritoneal primary or fallopian tube cancer. (ucsf.edu)
  • To determine if surgical secondary cytoreduction in addition to adjuvant chemotherapy increases quality of life (QOL) in patients with recurrent platinum-sensitive epithelial ovarian cancer, peritoneal primary or fallopian tube cancer, as measured by the Functional Assessment of Cancer Therapy-Ovarian (FACT-O) trial outcome index and Rand Short Form (SF)-36 physical functioning scale. (ucsf.edu)
  • A primary malignant neoplasm of epithelial liver cells. (lookformedical.com)
  • Primary mammary mucinous cystadenocarcinoma: cytological and histological findings. (nih.gov)
  • This randomized phase III trial studies carboplatin, paclitaxel and gemcitabine hydrochloride when given together with or without bevacizumab after surgery to see how well it works in treating patients with ovarian, epithelial, primary peritoneal, or fallopian tube cancer that has come back. (ucsf.edu)
  • It is not yet known whether combination chemotherapy is more effective when given with or without bevacizumab after surgery in treating patients with ovarian, epithelial, primary peritoneal, or fallopian tube cancer. (ucsf.edu)
  • A Phase III Randomized Controlled Clinical Trial of Carboplatin and Paclitaxel (or Gemcitabine) Alone or in Combination With Bevacizumab (NSC #704865) Followed by Bevacizumab and Secondary Cytoreductive Surgery in Platinum-Sensitive, Recurrent Ovarian, Peritoneal Primary and Fallopian Tube Cancer. (ucsf.edu)
  • We determined the histo-pathological features of surgically removed ovarian tumours. (bvsalud.org)
  • Results: The highest incidence of ovarian tumours was within the age range of 20-45 years. (bvsalud.org)
  • Testicular cancer represents 1% of adult neoplasms and 5% of urological tumours, with three to ten new cases per 100,000 males/per year in Western societies [ 6 ]. (uroweb.org)
  • Mucinous cystadenocarcinoma account for about a fifth of appendix tumours, these produces mucin (a jelly-like substance). (cancerindex.org)
  • A 35 cm right ovarian mass was identified, with focal previous rupture of the external surface. (hindawi.com)
  • Angiosarcoma may present a challenge in intraoperative frozen section diagnosis of an ovarian mass. (hindawi.com)
  • To our knowledge, less than 40 cases of ovarian angiosarcoma have been reported in English literature [ 1 - 3 ]. (hindawi.com)
  • Only 5 previous cases of angiosarcoma related to mucinous tumors have been reported [ 1 , 2 , 5 - 7 ]. (hindawi.com)
  • Angiosarcoma arising in an ovarian fibroma: a case report. (symptoma.com)
  • mucinous and Brenner malignant tumors potentially develop from the Walthard nests. (biomedcentral.com)
  • The age-specific incidence of ovarian epithelial cancer rises from the age of 20 to 80 and subsequently declines[ 2 ]. (biomedcentral.com)
  • [1] Complications may include ovarian torsion , testicular torsion , or hydrops fetalis . (mdwiki.org)