Squamous Cell CarcStromal TumorsMerkel Cell CarcMultiple MyelomaMelanomaLymphomaUterusLesionsSarcomaAdenocarcinomaRetinoblastomaFallopian Tube CancerHyperplasiaEndometrioidHepatocellularBasal Cell CarcColon CancerPrognosisGlandularBenignCytoreductive surgeryGynecologic cancerMetastaticPapillaryNeuroendocrineMalignanciesVulvaInvasiveRenal cellPrimaryCervixVaginal cancersChemotherapyBiopsyColorectalPrognosticRecurrent vulvar
Squamous Cell Carc7
- Squamous cell carcinoma (SCC) in various morphological forms needs to be separated from other epithelial tumors for treatment modality selection. (cytojournal.com)
- The two most common types of nonmelanoma skin cancer are basal cell carcinoma and squamous cell carcinoma. (moffitt.org)
- Each year, approximately 1.8 million cases of squamous cell carcinoma are diagnosed. (moffitt.org)
- Like basal cell carcinoma, squamous cell carcinoma usually appears on areas of the body that have been exposed to the sun. (moffitt.org)
- However, squamous cell carcinoma can also develop on the lips, mucous membranes (like the skin that lines the mouth or nose) and parts of the body where patients have experienced chronic inflammatory skin conditions. (moffitt.org)
- Although squamous cell carcinoma is more likely than basal carcinoma to spread or metastasize to distant areas of the body, it's still relatively rare for it to do so. (moffitt.org)
- Although basal cell carcinoma and squamous cell carcinoma make up the large majority of nonmelanoma skin cancer cases, there are various other rare forms of this malignancy that together comprise a small percentage of the total number of diagnoses. (moffitt.org)
Stromal Tumors1
- Carcinoma of cervix is classified as per the WHO classification into primary tumors which are predominantly epithelial tumors, mesenchymal tumors and tumor like lesions, mixed epithelial stromal tumors, melanocytic, germ cell, and lymphoid tumors. (cytojournal.com)
Merkel Cell Carc1
- Merkel cell carcinoma develops in the hormone-producing cells of the skin and hair follicles. (moffitt.org)
Multiple Myeloma1
- Celgene Inc. said on Sunday its cancer drug Thalomid improved survival by a significant amount in elderly patients with multiple myeloma, a form of blood cancer. (health.am)
Melanoma1
- Malignant Melanoma -- Part V. Breast Cancer -- 22. (nshealth.ca)
Lymphoma4
- In mouse models of leukemia and lymphoma, CREBBP has been shown to function as a tumor suppressor, where the loss of CREBBP-mediated acetylation and activation of p53 drives tumorigenesis. (fredhutch.org)
- Some of the body's lymphocytes (immune cells) are found in the skin, so when the cancer originates there, it is called cutaneous lymphoma. (moffitt.org)
- Depending on the type of lymphocytes affected (B cells or T cells), this type of skin cancer may be classified as cutaneous B-cell lymphoma or cutaneous T-cell lymphoma . (moffitt.org)
- Nodal Malignant Lymphoma (With Comments on Extranodal Malignant Lymphoma and Metastatic Cancer) -- Part IX. (nshealth.ca)
Uterus1
- Solitary tumors of the uterus which arise de novo from the mesenchymal cells of the myometrium. (brainscape.com)
Lesions3
- Papillary serous, clear-cell, and mixed mesodermal tumors are all considered grade 3 lesions. (medscape.com)
- It proved to be a valid biomarker especially in detecting squamous intraepithelial lesions in cervical liquid-based samples and in discerning these lesions from their mimickers, as well as in ovarian, endometrial, vulvar, primary and metastatic melanomas, breast, pancreatic and renal cell carcinomas. (medsci.org)
- Menometrorrhagia, which involves both excessive and irregular bleeding, should be distinguished from menorrhagia, and usually involves anovulatory cycles or genital lesions such as endometrial or cervical cancer. (mhmedical.com)
Sarcoma2
- At Fred Hutchinson Cancer Center, our experts offer multidisciplinary, team-based soft tissue sarcoma treatment as well as bone cancer treatment, including advanced therapies and new options that are only available through clinical trials. (fredhutch.org)
- Because there are more than 70 subtypes of sarcoma - depending on the nearby tissue, the affected area of the bone or the type of cells creating the tumor - there is no one way to treat everyone. (fredhutch.org)
Adenocarcinoma2
- Endometrial cancer is usually endometrioid adenocarcinoma. (msdmanuals.com)
- General references Endometrial cancer is usually endometrioid adenocarcinoma. (msdmanuals.com)
Retinoblastoma1
- In addition to p53, the retinoblastoma 1 (Rb1) protein is also a tumor suppressor. (fredhutch.org)
Fallopian Tube Cancer1
- Fallopian tube cancer is the least common of gynaecological malignancies. (annals.edu.sg)
Hyperplasia5
- Chromosome 17p is frequently involved, which contains the p53 gene known to confer a poor prognosis in endometrial cancers when mutated or deleted, and which plays an important role in the transition to carcinoma from atypical hyperplasia. (medmuv.com)
- What is endometrial hyperplasia? (missionforvisionusa.org)
- What are some of the risk factor that can possibly result in endometrial hyperplasia? (missionforvisionusa.org)
- What are some histological findings of endometrial hyperplasia? (missionforvisionusa.org)
- Endometrial hyperplasia is classified by its cytology and glandular tissue. (lookformedical.com)
Endometrioid4
- Although this most common gynecologic cancer carries the best prognosis, it is important to differentiate between the classic endometrioid tumors that tend to be estrogen dependent and well differentiated, from other less common high-risk uterine malignancies, such as uterine papillary serous carcinomas (UPSCs), clear cell carcinomas, mixed mullerian tumors (MMTs), or sarcomas, which appear to have a different biology. (medmuv.com)
- Kirsten (Ki)-ras activating point mutations in codons 12 and 13 have been implicated in the development of atypical endometrial hyperplasias and endometrioid carcinomas in Japanese women, as well as in colon cancers. (medmuv.com)
- Endometrioid cancers arising in Japanese women tend to be high grade and deeply invasive, are less common than in the United States , and are not generally associated with hormonal exposure. (medmuv.com)
- Notable was the almost complete absence of Ki-ras mutations in an aggressive form of endometrial cancer, UPSC, when compared to the usual endometrioid tumors. (medmuv.com)
Hepatocellular1
- Introduction: Hepatitis B virus (HBV) is a major public health problem affecting 400 million people worldwide, and is a common cause of chronic liver failure (cirrhosis) and hepatocellular carcinoma. (bvsalud.org)
Basal Cell Carc3
- Basal cell carcinoma is the most common type of skin cancer, with approximately 3.6 million cases diagnosed in the United States each year. (moffitt.org)
- Researchers agree that long-term ultraviolet (UV) radiation exposure can cause basal cell carcinoma to develop, so it commonly occurs in places that have been regularly exposed to the sun (such as the face and neck). (moffitt.org)
- Fortunately, basal cell carcinoma rarely spreads (metastasizes) to other areas of the body. (moffitt.org)
Colon Cancer2
- The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA254759(CD24 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (cusabio.com)
- CD133+CD24lo phenotype defines 5-FU-resistant human colon cancer stem cell-like cells. (cusabio.com)
Prognosis7
- thus the hereditary form of endometrial cancer alone does not appear to portend a worse prognosis than the sporadic form. (medmuv.com)
- List the staging categories of endometrial carcinoma and the relationship to prognosis. (missionforvisionusa.org)
- Zurück zum Zitat Haffty BG, Fischer D, Beinfield M, McKhann C (1991) Prognosis following local recurrence in the conservatively treated breast cancer patient. (springermedizin.de)
- Correctly identifying the type of cancer that a patient has is critical, since this information will affect their prognosis and treatment options. (moffitt.org)
- Early detection and appropriate treatment can significantly enhance a pancreatic cancer patient's prognosis. (moffitt.org)
- The impact of these ancillary investigations on diagnosis, and as biomarkers of prognosis and prediction of response to treatment is summarised, as is the effect of adjuvant treatments on cancers. (nshealth.ca)
- Experience based clues are given throughout as aids to tumour typing, grading, staging, and gauging prognosis and response to treatment. (nshealth.ca)
Glandular1
- The grade of the tumor is based primarily on the amount of solid growth of its glandular component. (medscape.com)
Benign3
- Most often, these tumors are benign, although it is possible for them to be malignant and to spread or metastasize. (moffitt.org)
- Solitary or multiple benign hepatic vascular tumors, usually occurring in women of 20-50 years of age. (lookformedical.com)
- for instance, women younger than 30 years with an adnexal mass are more likely to have a benign cystic teratoma or other germ cell tumors, whereas women older than 30 years with an adnexal mass are more likely to have epithelial tumors. (mhmedical.com)
Cytoreductive surgery1
- Correlation between progression-free survival and overall survival in patients with ovarian cancer after cytoreductive surgery: a systematic literature review. (ucla.edu)
Gynecologic cancer1
- A reduction in GI toxicity is likely to improve the quality of life in individuals with gynecologic cancer. (bcbsnd.com)
Metastatic2
- Although adjuvant radiotherapy is commonly used to manage advanced or metastatic cervical and endometrial cancer, it is sometimes administered as adjuvant therapy for ovarian cancer. (medscape.com)
- We believe that CD24 is a key molecule of metastatic progression in the epithelial-mesenchymal-transition phenomenon and a promising therapeutic target for advanced ovarian cancer. (cusabio.com)
Papillary1
- Long-term survival after paclitaxel plus platinum-based combination chemotherapy for extraovarian peritoneal serous papillary carcinoma: is it different from that for ovarian serous papillary cancer? (bmj.com)
Neuroendocrine9
- Small cell lung cancer (SCLC) is a neuroendocrine carcinoma that tends to grow rapidly, and accounts for about 15% of all lung cancers. (fredhutch.org)
- Additionally, the tumor suppressor activity of CREBBP was also demonstrated in other neuroendocrine tumors such as pituitary and thyroid tumors using genetic mouse models where Rb1 , Tpr53 and Crebbp genes are deleted in neuroendocrine cells. (fredhutch.org)
- Given these in vivo data, the authors reasoned that Crebbp loss cooperates with Rb1/Trp53 deletion to drive tumorigenesis in neuroendocrine tumors through gene expression, and compared the transcriptomes of tumors with and without Crebbp deletion. (fredhutch.org)
- CREBBP expression in neuroendocrine tumor cells promotes a cellular adhesion related transcriptional program, where E-CADHERIN (CDH1) was of particular interest. (fredhutch.org)
- Dr. MacPherson explained these findings and how they are relevant in other neuroendocrine tumors: "In our studies, Crebbp loss cooperated with Rb/p53 loss to promote not only SCLC, but neuroendocrine pituitary and thyroid tumors as well. (fredhutch.org)
- Background: Nearly 30% of neuroendocrine tumors (NETs) have evidence of immunohistochemical (IHC) expression of estrogen (ER) and/or progesterone (PR) receptors. (bvsalud.org)
- Trial registry name: Study of Tamoxifen in Well Differentiated Neuroendocrine Tumors and Hormone Receptor Positive Expression (HORMONET). (bvsalud.org)
- These neuroendocrine tumors can be nonfunctional (non-hormone-producing) or functional, causing the pancreas to overproduce certain hormones. (moffitt.org)
- Neuroendocrine tumors are further classified based on the types of hormones they produce, such as gastrin, glucagon, insulin, somatostatin and vasoactive intestinal peptide. (moffitt.org)
Malignancies3
- Gynecologic cancers were among the first malignancies treated with ionizing radiation, more than a century ago. (medscape.com)
- Urothelial carcinoma (UC) is one the most common malignancies derived from the urothelium of the lower urinary tract. (medsci.org)
- The pathological features of the common carcinomas are detailed and non-carcinomatous malignancies are also summarised. (nshealth.ca)
Vulva3
- Current strategies for treating cancers of the uterine corpus , uterine cervix , vulva , and vagina are tailored to the clinical and pathologic stage of disease. (medscape.com)
- Carcinoma of the vulva is an uncommon malignancy, but one that is amenable to early diagnosis if symptoms and signs are appropriately investigated. (annals.edu.sg)
- Keywords: carcinoma of vulva, laparoscopic minimally inv. (cn1699.cn)
Invasive4
- Cancers will recur in 30-80% of cases, with a progression to muscle invasive disease of 1-45% within 5 year [ 2 , 3 ]. (medsci.org)
- The objective of a cervical screening programme is to prevent invasive cancer of the cervix by detecting and treating pre-invasive disease of the cervix. (annals.edu.sg)
- Gestational trophoblastic diseases (GTD) encompass a spectrum of interrelated conditions: Hydatidiform mole (HM) Invasive mole (IM) Choriocarcinoma (CC) Placental site trophoblastic tumour (PSTT) This article is available only as. (annals.edu.sg)
- In invasive cancers, a superficially invasive SCC is a well-defined entity. (cytojournal.com)
Renal cell2
- Types include: Cancer of the female genital organs: (Cervical cancer, Endometrial cancer, Ovarian cancer, Uterine cancer, Vaginal cancer, Vaginal tumors, Vulvar cancer) Cancer of the male genital organs (Carcinoma of the penis, Prostate cancer, Testicular cancer) Cancer of the urinary organs (Bladder cancer, Renal cell carcinoma) Kurman RJ (2013). (wikipedia.org)
- Renal Cell and Renal Pelvis/Ureter Carcinoma -- 30. (nshealth.ca)
Primary4
- The primary source of estrogen in normally cycling adult women is the ovarian follicle, which secrets 70 to 500 mcg of estradiol daily, depending on the phase of the menstrual cycle. (nih.gov)
- A soft polypoid mass, which is a rare form of primary vaginal cancer. (brainscape.com)
- The primary end point was disease control rate (DCR) at week 24 by Response Evaluation Criteria in Solid Tumors version 1.1. (bvsalud.org)
- Dostarlimab for Primary Advanced or Recurrent Endometrial Cancer. (ucla.edu)
Cervix3
- What treatments are available for squamous dysplasia and carcinoma of the cervix? (missionforvisionusa.org)
- Carcinoma cervix is not the only cancer caused by HPV. (cytojournal.com)
- Produces a "barrel cervix" if the tumor encircles the cervix and invades the underlying stroma. (brainscape.com)
Vaginal cancers1
- High-risk HPV is implicated in causation of various other cancers such as anal cancers, oropharyngeal cancers, vulval cancers, vaginal cancers, and penile cancers. (cytojournal.com)
Chemotherapy2
- Chemotherapy, radiation therapy or both may be given before or after surgery to reduce the risk of the cancer coming back. (fredhutch.org)
- Consultation for leukemia other body parts with lumps - all tumor therapy program and chemotherapy related issues (i.e. effect and side effects for choice of medicine). (cmu.edu.tw)
Biopsy3
- The gold standard for the detection of urothelial carcinoma is represented by urethro-cystoscopy and biopsy. (medsci.org)
- OBJECTIVES: To evaluate the prevalence of post-operative complications and quality of life (QoL) related to sentinel lymph node (SLN) biopsy vs systematic lymphadenectomy in endometrial cancer. (bvsalud.org)
- METHODS: A prospective cohort included women with early-stage endometrial carcinoma who underwent lymph node staging, grouped as follows: SLN group (sentinel lymph node only) and SLN+LND group (sentinel lymph node biopsy with addition of systematic lymphadenectomy). (bvsalud.org)
Colorectal3
- Treating colorectal cancer in the biomarker era - what's next? (esmo.org)
- Aspirin in colorectal cancer - has it still a place in secondary prevention? (esmo.org)
- Colorectal Carcinoma -- 7. (nshealth.ca)
Prognostic4
- Prognostic factors in ovarian carcinoma stage III patients. (bmj.com)
- Cancer Information Summaries from the National Cancer Institute's Physician Data Query (PDQ®) provide prognostic and treatment information for major types of adult and pediatric cancers. (vicc.org)
- When multivariate analysis was used to determine if HER-2/neu was an independent prognostic factor in endometrial cancers taking into account other molecular features such as DNA ploidy, epidermal growth factor receptor, or p53 status, HER-2/neu status failed to achieve significance. (medmuv.com)
- 8th edition TNM and WHO classifications of cancers are incorporated, with comments on any associated pathology, diagnostic clues and prognostic criteria supplemented visually by line diagrams. (nshealth.ca)
Recurrent vulvar1
- To our knowledge this is the first reported case of an isolated vesicocutaneous fistula related to previous radiation therapy for recurrent vulvar cancer. (annals.edu.sg)