• a ≥1 point decrease on the EDSS sustained for 6 consecutive months for patients with a baseline EDSS ≥2), and analysed efficacy outcomes for subgroups based on age, sex, geographic region, MRI-T1 brain volume, MRI-T2 lesion volume, disease duration, number of previous relapses within 2 years, and EDSS. (nih.gov)
  • Patients should be adequately characterized at the time they enter the study to give a baseline on all variables to be used as outcome measures and all variables known to influence prognosis (e.g., psychiatric diagnoses, demographics, significant relationships, addict's environment, and payment source). (asam.org)
  • Objective: Exploratory analysis to evaluate any differences in patient characteristics and efficacy outcomes by baseline PSA level in the AFFIRM trial. (icr.ac.uk)
  • The post hoc design of this analysis was not statistically powered to assess the relationship between baseline PSA and clinical efficacy outcomes. (icr.ac.uk)
  • Results Baseline assessment observed no significant differences between experimental and control groups for the variables related to outcomes. (bmj.com)
  • ORLANDO, Fla., Jan 24, 2008 (BUSINESS WIRE) -- Amgen (NASDAQ: AMGN) today announced the results of a biomarker analysis which indicated that in metastatic colorectal cancer (mCRC) patients who have failed all other chemotherapeutic regimens, the efficacy of Vectibix(TM) (panitumumab) monotherapy is confined to patients with non-mutated (wild-type) KRAS tumors. (amgen.com)
  • THOUSAND OAKS, Calif. , Aug. 28, 2017 /PRNewswire/ -- Amgen (NASDAQ:AMGN) today announced a new analysis from the Repatha ® (evolocumab) cardiovascular outcomes study (FOURIER) that showed a statistically significant relationship between lower achieved low-density lipoprotein cholesterol (LDL-C) levels and lower cardiovascular event rates in patients with established atherosclerotic cardiovascular disease. (amgen.com)
  • Efficacy of ixekizumab compared to etanercept and placebo in patients with moderate-to-severe plaque psoriasis and non-pustular palmoplantar involvement: results from three phase 3 trials (UNCOVER-1, UNCOVER-2 and UNCOVER-3). (springer.com)
  • All disability and relapse outcomes showed evidence of beneficial effects of alemtuzumab compared with interferon beta-1a across all analysed patient subsets, and no subgroup of patients consistently responded better than others to alemtuzumab. (nih.gov)
  • The number of patients for whom outcome data are known at the time of follow-up should be specified. (asam.org)
  • However, the predictive value of preoperative self-efficacy and outcome expectancies on functional recovery during hospital stay and LoS has not yet been determined in patients after THR or TKR. (uu.nl)
  • Preoperatively, patients completed the Dutch translation of the Self-Efficacy for Rehabilitation Outcome Scale and the Hip or Knee Replacement Expectations Survey. (uu.nl)
  • For infants treated with one PT type during the 2-week intervention period (n = 1223), adjusted outcomes at discharge and 18 to 22 months corrected age were determined. (rti.org)
  • The outcome measurements included HbA1c concentration, DM self efficacy scale, dietary behaviours, body mass index (BMI), and waist: hip ratio. (bmj.com)
  • Repeated measure of analysis of variance showed pronounced improvement in DM self efficacy scale and BMI among the experimental group with significant interaction. (bmj.com)
  • All investigated DES were similar with regards to efficacy endpoints, except for Endeavor zotarolimus-ES and paclitaxel-ES, which were associated with significantly increased the odds of target lesion and target vessel revascularisations compared with other devices. (ru.nl)
  • Additionally, we aimed to describe a new outcome measure in multiple sclerosis research: sustained reduction in disability. (nih.gov)
  • Parent-perceived child self-efficacy was inversely associated with parent-reported child GI symptom severity and disability, and parental protectiveness mediated these associations. (mdpi.com)
  • These results suggest that parents who perceive their child to have low self-efficacy to cope with pain respond more protectively when they believe he/she is in pain, and this, in turn, is associated with higher levels of GI symptoms and disability in their child. (mdpi.com)
  • In the past year, Psoriasis Area and Severity Index (PASI) was the most frequently used outcome measure in phase III and IV clinical trials evaluating psoriasis treatments. (springer.com)
  • Psoriasis Scalp Severity Index (PSSI) was the most commonly utilized regional physician reported outcome measure and Dermatology Quality of Life Index (DLQI) was the most commonly used patient reported outcome. (springer.com)
  • Findings were that individuals with high self-efficacy manifested greater self-rated progress, and less general and dissertation-specific depression than individuals with low self-efficacy. (bepress.com)
  • To compare the 5-year subjective and objective outcomes of transobturator tension-free vaginal tape alone versus the same procedure with concomitant pelvic floor repair surgery for pelvic organ prolapse in women with urinary stress incontinence. (hkmj.org)
  • RCTs are often used to test the efficacy or effectiveness of various types of medical intervention and may provide information about adverse effects, such as drug reactions. (wikipedia.org)
  • There is, however, little information on the efficacy of TO-TVT in this group of women. (hkmj.org)
  • The three major intragroup process constructs examined are intra-group conflict, team cohesion, and team-efficacy. (wikipedia.org)
  • Telemedicine has been proposed as a mean for timely detection of exacerbation, but the available evidence is inadequate to provide conclusive information on its efficacy. (nih.gov)
  • Although limitations, our long term experience suggest that significant improvements in symptomatic and urodynamic outcomes of 120W HPS laser PVP. (koreamed.org)
  • Efficacy of multiparametric telemonitoring on respiratory outcomes in elderly people with COPD: a randomized controlled trial. (nih.gov)
  • Conclusions Abatacept in combination with MTX had greater clinical efficacy in pts who were anti-CCP2 IgM positive at BL than in those who were anti-CCP2 IgM negative at BL, and in those who seroconverted over time than those who did not, suggesting that the impact on ACPA is associated with clinical benefit. (bmj.com)
  • 7 The development of transobturator TVT (TO-TVT) reduced the rate of complications with comparable efficacy to retropubic TVT in the short term. (hkmj.org)
  • Prior to Seminar, contact with students provided the most important source of efficacy information. (bepress.com)