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Diabetes Mellitus, Type 2Diabetes Mellitus, Type 1Diabetic AngiopathiesDiabetes MellitusHypoglycemic AgentsBlood GlucoseDiabetic NephropathiesDiabetic NeuropathiesHemoglobin A, GlycosylatedInsulinDiabetes Mellitus, ExperimentalCase-Control StudiesDiabetes ComplicationsRisk FactorsObesityDiabetic RetinopathyDiabetes, GestationalTreatment OutcomePregnancy in DiabeticsHyperglycemiaDiabetic FootStreptozocinGlucose Tolerance TestOutcome Assessment (Health Care)Follow-Up StudiesRetrospective StudiesProspective StudiesTime FactorsInsulin ResistanceIslets of LangerhansPrevalenceCohort StudiesAlbuminuriaPregnancy OutcomeDiabetic DietGlucoseBody Mass IndexHypertensionPregnancyIncidenceCardiovascular DiseasesHypoglycemiaPrediabetic StateMice, Inbred NODDiabetic CardiomyopathiesBiological MarkersDiabetic KetoacidosisRisk AssessmentInsulin-Secreting CellsMetforminC-PeptideGlucose IntoleranceSulfonylurea CompoundsAge FactorsCross-Sectional StudiesMultivariate AnalysisBlood Glucose Self-MonitoringPrognosisFastingAlloxanBlood PressureUnited StatesPredictive Value of TestsReference ValuesBody WeightLogistic ModelsDiabetes InsipidusGlutamate DecarboxylaseSeverity of Illness IndexSex FactorsFructosamineRegression AnalysisProportional Hazards ModelsGlycosuriaDisease ProgressionOdds RatioKidney Failure, ChronicLipidsComorbidityInfant, NewbornChi-Square DistributionCoronary Artery DiseaseTriglyceridesDisease Models, AnimalGlycosylation End Products, AdvancedJapanMetabolic Syndrome XPancreasRats, WistarInsulin Infusion SystemsGenetic Predisposition to DiseaseAnalysis of VarianceOutcome and Process Assessment (Health Care)HyperlipidemiasIslets of Langerhans TransplantationKidneyDipeptidyl-Peptidase IV InhibitorsDiabetic ComaGenotypeOxidative Stress
ComplicationsVascularMicro-angiopathyProgression of diabeticClinicalT2DMKetoacidosisGlycemicGangrenePreventionPatientsMetabolismAcuteRetinopathy studyObesityIncreases the riskGestational diabetesOccurrenceFoot ulcersLong-term outcomesBlood glucose levelsEndocrineAmputationsComplicationCerebralAbstractRiskMicrovascular diseaseIllnessHyperglycemiaEndocrinologyChronicHbA1cPancreasPerinatalUKPDSSeverityTreatmentDiseasesPregnancyStrokesPriseInjectionsHyperglycemicOnsetCommonMechanisms
Complications30
  • To assess ethnic disparities in the incidence of diabetic complications within a nonprofit prepaid health care organization. (nih.gov)
  • AIMS/HYPOTHESIS: The aim of this study was to develop a simulation model for type 2 diabetes that can be used to estimate the likely occurrence of major diabetes-related complications over a lifetime, in order to calculate health economic outcomes such as quality-adjusted life expectancy. (ox.ac.uk)
  • METHODS: Equations for forecasting the occurrence of seven diabetes-related complications and death were estimated using data on 3642 patients from the United Kingdom Prospective Diabetes Study (UKPDS). (ox.ac.uk)
  • The limited available evidence suggests that near-normal glycemic targets should be the standard for younger patients with relatively recent onset of type 2 diabetes mellitus and little or no micro- or macrovascular complications, with the aim of preventing complications over the many years of life. (nih.gov)
  • In addition, individuals with diabetes must make lifestyle changes, such as consuming a healthy diet plan and getting routine workout, to help manage their blood sugar levels and avoid complications. (microqnix.com)
  • Dr. Crandall has served on several grant review panels (NIH and ADA) and is active as a journal reviewer, including as Associate Editor of the Journal of Gerontology (2005-2012) and member of the editorial board for the Journal of Diabetes and its Complications. (einsteinmed.edu)
  • . Journal of Diabetes and its Complications 2008;22:224-228. (einsteinmed.edu)
  • Long-term complications of diabetes develop gradually. (workout-transalp.fr)
  • What are circulatory complications of diabetes? (workout-transalp.fr)
  • E08.59 Diabetes mellitus due to underlying condition with other circulatory complications E08.6 Diabetes mellitus due to underlying condition with other specified complications E08.61Diabetes mellitus due to underlying condition with diabetic arthropathy E08.610 Diabetes mellitus due to underlying condition with diabetic neuropathicarthropathy Diabetes mellitus due to underlying … The code E13.59 is valid during the fiscal year 2021 from October 01, 2020 through September 30, 2021 for the submission of HIPAA-covered transactions. (workout-transalp.fr)
  • E11.59 is a valid billable ICD-10 diagnosis code for Type 2 diabetes mellitus with other circulatory complications.It is found in the 2022 version of the ICD-10 Clinical Modification (CM) and can be used in all HIPAA-covered transactions from Oct 01, 2021 - Sep 30, 2022. (workout-transalp.fr)
  • complications 7 Circulatory None 8 Other specified complications Unspecified complications 9 Unspecified complications We investigated the trend of diabetic vascular complication-related deaths between 2000 and 2016 in the global diabetes … Find out here how to recognize the common symptoms of diabetes. (workout-transalp.fr)
  • Short description: Oth diabetes mellitus with other circulatory complications. (workout-transalp.fr)
  • But some may not understand that many of the most common complications of diabetes stem from one primary issue: the havoc that high blood sugar, also called hyperglycemia, causes for the … Possible complications include: Cardiovascular disease. (workout-transalp.fr)
  • Complications of diabetes are secondary diseases that are a result of elevated blood glucose levels that occur in diabetic patients. (wikipedia.org)
  • These complications can be divided into two types: acute and chronic. (wikipedia.org)
  • Acute complications are complications that develop rapidly and can be exemplified as diabetic ketoacidosis (DKA), hyperglycemic hyperosmolar state (HHS), lactic acidosis (LA), and hypoglycemia. (wikipedia.org)
  • The complications of diabetes can dramatically impair quality of life and cause long-lasting disability. (wikipedia.org)
  • Other health problems compound the chronic complications of diabetes such as smoking, obesity, high blood pressure, elevated cholesterol levels, and lack of regular exercise. (wikipedia.org)
  • Complications of diabetes are a strong risk factor for severe COVID-19 illness. (wikipedia.org)
  • Diabetic ketoacidosis (DKA) is one of the life-threatening severe complications of diabetes that demands immediate attention and intervention. (wikipedia.org)
  • Diabetes mellitus (DM) is associated with macrovascular and microvascular complications. (hindawi.com)
  • Diabetes mellitus (DM) is associated with macrovascular and microvascular complications (coronary artery disease, ischemic stroke, peripheral arterial disease, nephropathy, and retinopathy) [ 1 , 2 ]. (hindawi.com)
  • Platelets have a "key role" in atherogenesis and its thrombotic complications in subjects with DM [ 3 ], and the concomitant presence of multiple "classical" cardiovascular risk factors (arterial hypertension, cigarette smoking, and hyperlipidemia) in diabetic subjects contributes to enhanced atherothrombotic risk. (hindawi.com)
  • The clusters differed in the clinical characteristics of patients, the frequency and risk of diabetic complications. (bvsalud.org)
  • Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. (ox.ac.uk)
  • OBJECTIVE: To determine whether tight control of blood pressure prevents macrovascular and microvascular complications in patients with type 2 diabetes. (ox.ac.uk)
  • CONCLUSION: Tight blood pressure control in patients with hypertension and type 2 diabetes achieves a clinically important reduction in the risk of deaths related to diabetes, complications related to diabetes, progression of diabetic retinopathy, and deterioration in visual acuity. (ox.ac.uk)
  • One of the most problematic diabetic complications that is responsible for amputations is a diabetic foot ulcer and hypnosis has shown positive results in increasing peripheral blood circulation. (drdorothy.net)
  • Long-term complications from high blood sugar can include heart disease , strokes , diabetic retinopathy where eyesight is affected, kidney failure which may require dialysis , and poor circulation of limbs leading to amputations . (thediabeticpharmacist.com)
Vascular11
  • 2. Schmidt AM, Crandall J , Hori O, Cao R and Lakatta E. Elevated plasma levels of vascular cell adhesion molecule-1 (VCAM-1) in diabetic patients with microalbuminuria: a marker of vascular dysfunction and progressive vascular disease. (einsteinmed.edu)
  • The role of chronic administration of antiplatelet drugs in primary prevention of arterial vascular events is known to be less clear than in secondary prevention, and, also in diabetic patients, the decision to give primary prophylaxis should be taken on an individual-patient basis, after a careful evaluation of the balance between the expected benefits and the risk of major bleedings. (hindawi.com)
  • Although, currently, treatment has proven useful in reducing vascular events, diabetic patients continue to have a higher risk of adverse cardiovascular events compared with those in nondiabetic patients. (hindawi.com)
  • This paper reviews the role of currently available antiplatelet drugs in primary and secondary prevention of vascular events in diabetic patients and the limitations of these drugs, and it discusses the role of novel and more potent antiplatelets and of new agents currently under clinical development. (hindawi.com)
  • Functional and anatomical abnormalities of endothelium may represent a pathway to the increased vascular permeability and accelerated atherosclerosis characteristic of diabetes. (diabetesjournals.org)
  • Also, mind-body interventions for vascular issues have been reported to be effective in relieving diabetic angiopathy together with biofeedback. (drdorothy.net)
  • See Clinical Findings in Diabetes Mellitus, a Critical Images slideshow, to help identify various cutaneous, ophthalmologic, vascular, and neurologic manifestations of DM. (medscape.com)
  • This review will summarize the updated research progress on APOE functions and its role in Alzheimer's disease, Parkinson's disease, cardiovascular diseases, multiple sclerosis, type 2 diabetes mellitus, Type III hyperlipoproteinemia, vascular dementia, and ischemic stroke. (dovepress.com)
  • 3 In this review, we discuss the biological functions of human APOE and its role in Alzheimer's disease (AD), Parkinson's disease (PD), cardiovascular diseases (CVD), multiple sclerosis (MS), type 2 diabetes mellitus (T2DM), vascular dementia (VD), and ischemic (occlusive) stroke (IS). (dovepress.com)
  • ABSTRACT Chronic diseases such as diabetes and vascular disease are a major public health problem in Lebanon, where primary care is not well developed. (who.int)
  • Yet the rising was to highlight the major burden of reason) for surgery according to the incidence of diabetes and vascular dis- amputation and to set standards for patient's hospital record. (who.int)
Micro-angiopathy1
Progression of diabetic4
Clinical22
  • The individualization of HbA(1c) targets has gained more traction after recent clinical trials in older patients with established type 2 diabetes mellitus failed to show a benefit from intensive glucose-lowering therapy on cardiovascular disease (CVD) outcomes. (nih.gov)
  • Dr. Crandall is Professor of Medicine at Albert Einstein College of Medicine, where she is director of the Diabetes Clinical Trials Unit and a principal investigator for several NIH sponsored clinical trials, including the Diabetes Prevention Program Outcome Study (for which she holds several national leadership positions, including Executive Committee membership) and the Glycemia Reduction Approaches in Diabetes (GRADE) study. (einsteinmed.edu)
  • The role of novel and more potent antiplatelet strategies, currently under clinical development, seems attractive in diabetic patients. (hindawi.com)
  • Large clinical trials have shown that antiplatelet agents are effective in the prevention of recurrent cardiovascular events in diabetes. (hindawi.com)
  • AIM: Identify clusters of type 2 diabetes mellitus in patients with different disease duration based on five variables: HbA1c, age at diagnosis, BMI, HOMA-IR, HOMA-B and study the clinical features and complication rates in each cluster in the Novosibirsk region. (bvsalud.org)
  • MATERIALS AND METHODS: Cluster analysis of K-means was performed in 2131 patients with T2DM, aged 44 to 70 years, with a duration of diabetes of 6.42±5.66 years, living in the Novosibirsk region based on 5 variables - HbA1c, age at -diagnosis, BMI, HOMA-IR, HOMA-B. All patients a complete clinical and laboratory examination. (bvsalud.org)
  • This study aimed to evaluate the clinical features and the clinical factors associated with prognosis of sudden sensorineural hearing loss (SSNHL) in diabetic patients. (ejao.org)
  • Therefore, we conducted a retrospective review to evaluate the clinical factors associated with prognosis and compare the efficacy of simultaneous and sequential systemic steroid and ITD treatment in diabetic patients with SSNHL. (ejao.org)
  • Also, we evaluated the clinical features of SSNHL in diabetic patients including the laboratory data which are known to be related to systemic inflammation and glycemic control. (ejao.org)
  • MAIN OUTCOME MEASURES: Predefined clinical end points, fatal and non-fatal, related to diabetes, deaths related to diabetes, and all cause mortality. (ox.ac.uk)
  • The recommendations can be accessed at American Diabetes Association DiabetesPro Professional Resources Online, Clinical Practice Recommendations - 2015. (medscape.com)
  • This clinical study enrolled 163 type 2 diabetes mellitus (T2DM) patients, who were divided into the diabetes with DF (84 cases) group, diabetes with no DF (79 cases) group. (biomedcentral.com)
  • Angle α, k-value and fibrinogen have clinical significance on the risk of occurrence and development of diabetic foot, which can contribute to early diagnosis and early clinical intervention in DF. (biomedcentral.com)
  • A large clinical study found that the prevalence of PAD in patients with T2DM was 23.5% [ 2 ], and diabetic patients with combined PAD are more likely to develop ulceration and gangrene of the limb, significantly increasing the risk of amputation. (biomedcentral.com)
  • The bidirectional association between Tuberculosis (TB) and Diabetes Mellitus (DM) is currently one of the major concerns for clinicians, as DM affects the disease presentation and clinical outcome of TB and vice versa [ 2 ]. (ijmrhs.com)
  • As there are no studies available in our settings, clinical and radiological profile of tuberculosis and diabetes mellitus is in high need for proper evaluation and management of the patients, hence this study was taken up to know the clinical and radiological profile of pulmonary tuberculosis and diabetes mellitus, understand various modes of presentation, etiological pattern, clinical-radiological correlation of the study population. (ijmrhs.com)
  • In the past this diabetic impotence has been regarded as a discrete clinical entity, providing one of the best examples of a physically-induced failure of erection. (ox.ac.uk)
  • In clinical strdies the emphasis has been on blood glucose values during the first few days after stroke The clinical relevance of the blood glucose level is difficult to assess as the level is modified by many factors such as diabetes, latent diabetic state, timing of blood sampling, intravenous infusions containing glucose, and stress. (docksci.com)
  • Rapid blood pressure control is safe but does not improve the clinical outcome. (medlink.com)
  • Triglyceride-glucose (TyG) index as a reliable surrogate of insulin resistance (IR) has been shown to be related to adverse clinical outcomes in patients with acute coronary syndrome, heart failure, ischemic stroke and so on. (biomedcentral.com)
  • Overall, the selected practices performed marginally better than national practices on the clinical indicators in the Quality and Outcomes Framework. (healthdatagateway.org)
  • Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves, Effect of financial incentives on incentivised and non-incentivised clinical activities: longitudinal analysis of data from the UK Quality and Outcomes Framework. (healthdatagateway.org)
T2DM4
  • DM, primarily type 2 DM (T2DM) is often associated with obesity, hypertriglyceridemia, and high cholesterol and is a risk factor for TB. (ejournals.ca)
  • BACKGROUND: Diabetes mellitus (T2DM) is a serious medical and social problem. (bvsalud.org)
  • The possibility of cluster analysis for different durations of diabetes, in different cohorts to identify phenotypic clusters of T2DM and validation by reproducing clusters is relevant. (bvsalud.org)
  • CONCLUSION: Cluster analysis in patients with different durations of diabetes mellitus confirmed the possibility of using cluster analysis to identify T2DM phenotypes in the Russian population. (bvsalud.org)
Ketoacidosis6
Glycemic6
  • One of the first steps in the management of patients with type 2 diabetes mellitus is setting glycemic goals. (nih.gov)
  • A close relationship between poor glycemic control and increased platelet activity (estimated by measuring mean platelet volume-MPV-as part of whole blood count) in patients with type 2 DM has been suggested [ 4 ]. (hindawi.com)
  • Also, the use of systemic steroids can worsen glycemic control in diabetic patients. (ejao.org)
  • INVOKANA ® is not recommended for use to improve glycemic control in patients with type 1 diabetes mellitus. (janssencarepath.com)
  • INVOKANA ® is not recommended for use to improve glycemic control in adults with type 2 diabetes mellitus with an eGFR less than 30 mL/min/1.73 m 2 . (janssencarepath.com)
  • INVOKANA ® is not indicated for glycemic control in patients with type 1 diabetes mellitus. (janssencarepath.com)
Gangrene3
  • In individuals with diabetes, the body's ability to produce or utilize insulin, a hormone that helps to regulate blood sugar levels, suffers diabetic peripheral angiopathy without gangrene. (microqnix.com)
  • Diabetes mellitus due to underlying condition with diabetic peripheral angiopathy with gangrene: E08.52 Assessment: 66 year old male with diabetic peripheral angiopathy. (workout-transalp.fr)
  • Lower-limb infections, gangrene, and diabetic foot ulcers were the most common precipitating medical events leading to the need for an amputation. (janssencarepath.com)
Prevention4
  • The influence of age on the effects of lifestyle modification and metformin in prevention of diabetes. (einsteinmed.edu)
  • Adherence to preventive medication: predictors and outcomes in the Diabetes Prevention Program. (einsteinmed.edu)
  • Diabetes prevention, detection and management should be prioritized in any attempt to reduce the current incidence of amputation in Lebanon. (who.int)
  • In Lebanon, the preva- could be achieved in order to support main indication was recorded for each lence of type 2 diabetes was 13.1% for the development of programmes for patient from either trauma, diabetes, those aged 30+ years in 1994-95 [2] amputation prevention and care. (who.int)
Patients40
  • A model to estimate the lifetime health outcomes of patients with type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS) Outcomes Model (UKPDS no. 68). (ox.ac.uk)
  • CONCLUSIONS/INTERPRETATIONS: The UKPDS Outcomes Model is able to simulate event histories that closely match observed outcomes in the UKPDS and that can be extrapolated over patients' lifetimes. (ox.ac.uk)
  • Its validity in estimating outcomes in other groups of patients, however, remains to be evaluated. (ox.ac.uk)
  • We randomly allocated 100 patients with diabetic foot into one of four groups. (who.int)
  • Streptococcus species [ 3 ], although an in- tion as determined by the Wagner classifi- creasing number of patients have been en- cation. (who.int)
  • However, somewhat higher targets should be considered for older patients with long-standing type 2 diabetes mellitus and evidence of CVD (or multiple CVD risk factors). (nih.gov)
  • FINDINGS: Between Aug 18, 2011, and Aug 14, 2013, we screened 12 133 patients, of whom 9901 with type 2 diabetes and additional cardiovascular risk factors were randomly assigned to either dulaglutide (n=4949) or an equal volume of placebo (n=4952). (mcmaster.ca)
  • Although these medicines are effective in treating … 172 - 174 In a retrospective study of >700 000 Veterans Affairs patients, using International Classification of Diseases-9 codes to identify diabetes mellitus, the risk of pulmonary embolism was 27% higher in the diabetic … It is characterized by high levels of sugar in the blood. (workout-transalp.fr)
  • It is considered a medical emergency and can affect both patients with T1D (type 1 diabetes) and T2D (type 2 diabetes), but it is more common in T1D. (wikipedia.org)
  • However, although the currently available treatments have proven to be useful in reducing ischemic events, diabetic patients continue to have a higher risk of adverse events compared with those in non-diabetic patients. (hindawi.com)
  • Cardiovascular (CV) diseases are the leading cause of morbidity and mortality in diabetic patients. (hindawi.com)
  • Cluster 3 in 18 patients with high function of ß-cells (HOMA-B 228.53±63.32%), severe insulin resistance (HOMA-IR 6.92±4.77), features were high incidence of men, shorter duration of diabetes, lower fasting glycemia and HbA1c, lower diastolic BP and eGFR, high incidence of early development of diabetic retinopathy after 4.00±3.6 years. (bvsalud.org)
  • Simultaneous intratympanic dexamethasone (ITD) injections with systemic steroid did not confer an additional hearing gain or an earlier recovery rate in diabetic patients with SSNHL. (ejao.org)
  • In the multivariate analysis, initial hearing thresholds of affected ear and timing of steroid treatment were significantly associated with hearing prognosis in diabetic patients with SSNHL. (ejao.org)
  • Diabetic patients with SSNHL tended to have increased NLR, LMR, and PLR, which are reported to be associated with microvascular angiopathy. (ejao.org)
  • Simultaneous ITD injections to improve hearing recovery in diabetic patients with SSNHL seems unnecessary. (ejao.org)
  • Additionally, microvascular problems in diabetic patients can affect the delivery and efficacy of systemic steroid in the cochlea [ 6 , 7 ]. (ejao.org)
  • Given this, systemic steroid use for SSNHL in diabetic patients may lead to poorer outcomes than are observed in those without DM [ 8 , 9 ]. (ejao.org)
  • However, previous studies of SSNHL have seldom focused on diabetic patients. (ejao.org)
  • We retrospectively reviewed the medical records of all diabetic patients who admitted to Dankook University Hospital for SSNHL between January 2014 and July 2018. (ejao.org)
  • After nine years of follow up the group assigned to tight blood pressure control also had a 34% reduction in risk in the proportion of patients with deterioration of retinopathy by two steps (99% confidence interval 11% to 50%) (P=0.0004) and a 47% reduced risk (7% to 70%) (P=0.004) of deterioration in visual acuity by three lines of the early treatment of diabetic retinopathy study (ETDRS) chart. (ox.ac.uk)
  • Intravenous Opdivo has helped transform the treatment of several solid tumor types over the past decade, but there remains a need for additional administration options to address treatment burden on patients and improve efficiencies in healthcare systems," said Gina Fusaro, Ph.D., vice president, global program lead, Bristol Myers Squibb. (businesswire.com)
  • Diabetes mellitus is a common endocrine disease in dogs and cats, occurring in about 1 of every 300 patients. (merckvetmanual.com)
  • A fingerstick glucose test is appropriate for virtually all patients with diabetes. (medscape.com)
  • [ 2 ] However, in patients at high risk (eg, those who have first-degree relatives with type 1 diabetes), it may be appropriate to perform annual screening for anti-islet antibodies before the age of 10 years, along with 1 additional screening during adolescence. (medscape.com)
  • All patients with type 1 diabetes should learn how to self-monitor and record their blood glucose levels with home analyzers and adjust their insulin doses accordingly. (medscape.com)
  • Patients with type 1 diabetes require lifelong insulin therapy. (medscape.com)
  • The long-term efficacy seen with the dual immunotherapy regimen in CheckMate -227 reinforce the importance of nivolumab plus ipilimumab to transform outcomes for appropriate patients with metastatic non-small cell lung cancer. (advfn.com)
  • Diabetic patients are at higher risk of developing tuberculosis and the bi-directional association is a major concern for clinicians. (ijmrhs.com)
  • A cross-sectional study was conducted on patients diagnosed with pulmonary tuberculosis and diabetes mellitus attending a tertiary care hospital in urban Telangana, India. (ijmrhs.com)
  • A higher number of acid-fast bacilli was observed on sputum microscopy in diabetic tuberculosis patients (3+ in 56%) while the majority of non-diabetic tuberculosis patients fall into the 1+ and 2+ categories. (ijmrhs.com)
  • Patients with diabetes mellitus who consume a carbohydrate-rich diet, smoke, and consume alcohol had a higher association with tuberculosis. (ijmrhs.com)
  • Symptomatology was similar in both groups except that hemoptysis was observed more in patients with diabetes and TB. (ijmrhs.com)
  • Family history of diabetes is an important clue for active DM screening in all TB patients and will help in the early detection of diabetes. (ijmrhs.com)
  • The risk of developing active TB is three-fold higher in those patients having Diabetes Mellitus (DM) in comparison to nondiabetic patients [ 1 ]. (ijmrhs.com)
  • This is a cross-sectional study conducted on patients diagnosed with pulmonary tuberculosis and diabetes mellitus attending the department of pulmonary medicine in ESIC Medical College, Hyderabad during the period from May 2019 to November 2019. (ijmrhs.com)
  • An increased risk of lower-limb amputations associated with INVOKANA ® use versus placebo was observed in CANVAS (5.9 vs 2.8 events per 1000 patient-years) and CANVAS-R (7.5 vs 4.2 events per 1000 patient-years), two randomized, placebo-controlled trials evaluating patients with type 2 diabetes who had either established cardiovascular disease or were at risk for cardiovascular disease. (janssencarepath.com)
  • 1988a) did not find a correlation between admission serum glucose concentration and neurologic outcome in patients with cerebral infarction. (docksci.com)
  • We've seen tremendous scientific advancements in the treatment of non-metastatic non-small cell lung cancer in recent years, and remain committed to researching new solutions that may help even more patients achieve better long-term outcomes," said Abderrahim Oukessou, M.D., vice president, thoracic cancers global program lead, Bristol Myers Squibb. (santaclara.com)
  • While many non-metastatic NSCLC patients are cured by surgery, 30% to 55% develop recurrence and die of their disease despite resection, contributing to a need for treatment options administered before surgery (neoadjuvant) and/or after surgery (adjuvant) to improve long-term outcomes. (santaclara.com)
Metabolism1
  • Diabetes mellitus is a chronic disorder of carbohydrate metabolism due to relative or absolute insulin deficiency . (merckvetmanual.com)
Acute3
  • Diabetes mellitus and cardiovascular disease increase the overall risk of acute and chronic osteomyelitis. (medscape.com)
  • Hypertriglyceridemia-induced acute pancreatitis seldom occurs in the second trimester of pregnancy with gestational diabetes mellitus. (bvsalud.org)
  • We report a case of abruptio placentae and epileptic seizure following perinatal hyperglycaemia in woman with gestational diabetes mellitus and hypertriglyceridemia-induced acute pancreatitis. (bvsalud.org)
Retinopathy study1
  • The women were scheduled for ophthalmologic examination, including visual acuity testing and fundus photography, before pregnancy, once in each trimester, and 4 months after birth, according to the principles defined in the Early Treatment for Diabetic Retinopathy Study ( 6 ). (diabetesjournals.org)
Obesity6
  • Type 2 diabetes is more common in older folks, type 2 diabetes has actually ended up being more widespread in younger people as an outcome of a marked increase in childhood obesity rates. (microqnix.com)
  • Type 2 diabetes, on the other hand, is frequently related to obesity and a sedentary lifestyle, but can also be caused by genetics or certain medical conditions. (microqnix.com)
  • Type 2 diabetes is frequently associated with obesity and a sedentary lifestyle. (microqnix.com)
  • Low Carb Program Join 450,000 people on the award-winning app to support healthier habits and weight loss for people with obesity, prediabetes and type 2 diabetes. (workout-transalp.fr)
  • Obesity is thought to be the primary cause of type 2 diabetes in people who are genetically predisposed to the disease. (thediabeticpharmacist.com)
  • Rates of diabetes have increased markedly over the last 50 years in parallel with obesity. (thediabeticpharmacist.com)
Increases the risk2
  • Diabetes mellitus increases the risk of active tuberculosis: A systematic review of 13 observational studies. (ejournals.ca)
  • Introduction Diabetes increases the risk of cardiovascular disease. (docksci.com)
Gestational diabetes4
  • The 3rd significant kind of diabetes, called gestational diabetes , impacts pregnant ladies who have never ever had the disease. (microqnix.com)
  • After delivery, blood sugar levels in women with gestational diabetes generally go back to normal. (microqnix.com)
  • The possibility of getting type 2 diabetes later on in life is increased for women who had gestational diabetes during pregnancy. (microqnix.com)
  • Type 2 diabetes makes up about 90% of cases of diabetes with the other 10% due primarily to diabetes mellitus type 1 and gestational diabetes . (thediabeticpharmacist.com)
Occurrence2
  • The primary endpoint was the first occurrence of any component of the composite outcome, which comprised non-fatal myocardial infarction, non-fatal stroke, or death from cardiovascular or unknown causes. (mcmaster.ca)
  • There is a lack of uniform quantitative standards for biomarkers that predict the risk of diabetic foot occurrence and progression. (biomedcentral.com)
Foot ulcers1
  • Hypnosis is powerful tool to induce relaxation, decrease psychological morbidity, often associated with diabetes, and accelerate wound healing, in case of diabetic foot ulcers. (drdorothy.net)
Long-term outcomes1
  • The model allows simulation of a range of long-term outcomes, which should assist in informing future economic evaluations of interventions in type 2 diabetes. (ox.ac.uk)
Blood glucose levels3
  • For people with type 2 diabetes, treatment might consist of lifestyle changes such as weight-loss and regular exercise, as well as oral medications to help control blood glucose levels. (microqnix.com)
  • Recently in a RCT, in person with type 1 diabetes , the hypnosis group decreased the standardized blood glucose levels, while the control group increased 3 ). (drdorothy.net)
  • Optimal diabetic control requires frequent self-monitoring of blood glucose levels, which allows rational adjustments in insulin doses. (medscape.com)
Endocrine2
  • Those who suffer the impact of negative psychological stresses through the dysfunctional activation of the autonomic nervous and endocrine systems are susceptible to creating diabetes. (drdorothy.net)
  • Chronic relapsing pancreatitis with progressive loss of both exocrine and endocrine cells and their replacement by fibrous connective tissue results in diabetes mellitus. (merckvetmanual.com)
Amputations1
  • La prévention du diabète, son dépistage et sa prise en charge doivent devenir prioritaires afin de tenter de réduire l'incidence actuelle des amputations au Liban. (who.int)
Complication2
  • Disparate access to quality health care is a common explanation for ethnic disparities in diabetic complication rates in the US population. (nih.gov)
  • Diabetic foot (DF) is a serious diabetic complication that refers to the destruction of the skin and deep tissues (including muscle and bone) distal to the ankle joint, often combined with arterial occlusion and infection of the lower extremity [ 1 ]. (biomedcentral.com)
Cerebral2
  • Hypertension and cerebral amyloid angiopathy (CAA) are the most common causes of primary ICH, but the mechanism of hemorrhage in both conditions is unclear. (nature.com)
  • In primary ICH, hypertension is thought to be the underlying cause in 65% of cases, followed by cerebral amyloid angiopathy (CAA). (nature.com)
Abstract1
  • ABSTRACT The effect of different antibiotics on the outcome of surgical care in the management of diabetic foot was investigated. (who.int)
Risk8
  • Some non-modifiable risk factors such as age at diabetes onset, type of diabetes, gender, and genetics may influence risk. (wikipedia.org)
  • Moreover, the concomitant presence of multiple "classical" cardiovascular risk factors in diabetic subjects contributes to enhanced atherothrombotic risk. (hindawi.com)
  • With associated microangiopathy or inflammatory processes, diabetes mellitus (DM) could be a risk factor for SSNHL [ 5 ]. (ejao.org)
  • Screening for type 1 diabetes in asymptomatic low-risk individuals is not recommended. (medscape.com)
  • However, most of the relevant studies have focused on the analysis of risk factors associated with the diabetic foot and comprehensive management. (biomedcentral.com)
  • Pregnancy is a prominent risk factor for the development and progression of retinopathy in women with type 1 diabetes. (diabetesjournals.org)
  • The Framingham study revealed that the risk of ischemic brain infarction in diabetics, after adjustment for several other risk factors, is twice that of non-diabetics (Kannel and McGee 1979). (docksci.com)
  • 1980). The pathogenetic mechanisms underlying this increased risk and the worse outcome after stroke have remained unsolved. (docksci.com)
Microvascular disease1
  • Growth hormone (GH) exerts many of its effects via the synthesis and release of IGF-I. IGF-I has been variably associated with diabetic microvascular disease, and a transient rise in IGF-I has been reported in the early phase of neovascularization of the retina ( 2 ). (diabetesjournals.org)
Illness4
  • Diabetes is a persistent illness that impacts the way the body processes blood sugar level (glucose). (microqnix.com)
  • Insulin resistance, an illness in which cells do not react to insulin as it should, is the precursor to type 2 diabetes . (microqnix.com)
  • To sum it up, Diabetes is a persistent illness that impacts the method the body processes blood sugar (glucose). (microqnix.com)
  • Type 1 diabetes is a chronic illness characterized by the body's inability to produce insulin due to the autoimmune destruction of the beta cells in the pancreas. (medscape.com)
Hyperglycemia3
  • Changes in Host Response to Mycobacterium tuberculosis Infection Associated With Type 2 Diabetes : Beyond Hyperglycemia. (ejournals.ca)
  • Over decades, steady interest in fructosamine was largely sustained by its role as a key intermediate structure in the Maillard reaction that is responsible for the organoleptic and nutritional value of thermally processed foods, and for pathophysiological effects of hyperglycemia in diabetes. (bvsalud.org)
  • Measurement of fructosamine in cats can be helpful to distinguish stress-induced hyperglycemia from diabetes. (merckvetmanual.com)
Endocrinology1
Chronic1
HbA1c1
  • Men and women (aged ≥50 years) with established or newly detected type 2 diabetes whose HbA1c was 9·5% or less (with no lower limit) on stable doses of up to two oral glucose-lowering drugs with or without basal insulin therapy were eligible if their body-mass index was at least 23 kg/m2. (mcmaster.ca)
Pancreas5
  • Diabetes arises from either inadequate insulin production by the pancreas or improper insulin utilization by the body's cells. (microqnix.com)
  • Type 1 diabetes is caused by the pancreas' inability to produce adequate insulin as a result of beta cell loss. (microqnix.com)
  • Type 1 diabetes is an autoimmune disorder in which the body's body immune system attacks and destroys the insulin-producing cells in the pancreas. (microqnix.com)
  • Type 2 diabetes is a metabolic disorder that occurs when the body ends up being resistant to the effects of insulin and/or the pancreas is not able to produce enough insulin to stay up to date with the body's requirements. (microqnix.com)
  • [ 2 ] This is in contrast to diabetes mellitus type 1 , in which there is an absolute insulin deficiency due to destruction of islet cells in the pancreas . (thediabeticpharmacist.com)
Perinatal1
UKPDS1
  • After examining the internal validity, the UKPDS Outcomes Model was used to simulate the mean difference in expected quality-adjusted life years between the UKPDS regimens of intensive and conventional blood glucose control. (ox.ac.uk)
Severity3
  • INTERPRETATION: Long-term dulaglutide use might reduce clinically relevant ischaemic stroke in people with type 2 diabetes but does not affect stroke severity. (mcmaster.ca)
  • The case fatality rate, severity of hemiparesis, functional outcome, and infarct size did not differ between these 2 groups. (docksci.com)
  • On the other hand, fasting blood glucose level of the non-diabetics correlated strongly with the severity of hemiparesis and predicted stroke outcome. (docksci.com)
Treatment8
  • Treatment for diabetes usually involves a mix of lifestyle modifications and medication. (microqnix.com)
  • For people with type 1 diabetes, treatment includes daily insulin injections and tracking of blood sugar level levels. (microqnix.com)
  • The treatment for diabetes typically includes a mix of way of life modifications and medication. (microqnix.com)
  • Ginsenosides extracted from ginseng, which is derived from the roots and rhizomes of Panax ginseng C. A. Meyer, have been used in China as an adjuvant in the treatment of diabetes mellitus. (frontiersin.org)
  • Rg1, Rg3, Rb1, and compound K demonstrated the most promising therapeutic prospects as potential adjuvant medicines for the treatment of diabetes. (frontiersin.org)
  • Diabetes is also associated with poor TB treatment outcomes. (ejournals.ca)
  • To date, Opdivo and Opdivo -based combinations have shown improved efficacy in the neoadjuvant, adjuvant or perioperative treatment of four tumor types: lung cancer, bladder cancer, esophageal/gastroesophageal junction cancer and melanoma. (santaclara.com)
  • Opdivo and Opdivo -based combinations are important treatment options with established benefit across many cancer types, including melanoma, renal cell carcinoma, non-small cell lung cancer, mesothelioma, head and neck cancer, and bladder cancer, as well as esophageal, gastric, and gastroesophageal junction cancers. (bms.com)
Diseases1
Pregnancy2
  • However, after it was shown that pituitary ablation could halt the progression of proliferative diabetic retinopathy, increased focus has been put on the hormonal changes with growth-stimulating potential that accompanies pregnancy ( 1 ). (diabetesjournals.org)
  • The aim of the present study was to examine the correlation between serum IGF-I and progression of retinopathy in diabetic pregnancy in 103 pregnant women with type 1 diabetes. (diabetesjournals.org)
Strokes1
Prise1
  • RÉSUMÉ Nous avons examiné l'effet de différents antibiotiques sur l'issue des soins chirurgicaux dans la prise en charge du pied diabétique. (who.int)
Injections1
Hyperglycemic1
  • 1988) but, on the other hand, smaller ischemic lesions and better outcome have been seen in both hyperglycemic (3ernigan et al. (docksci.com)
Onset2
Common4
  • Renal cell carcinoma (RCC) is the most common type of kidney cancer in adults, accounting for more than 431,000 new cases and 179,000 deaths worldwide each year. (businesswire.com)
  • Diabetic men are prone to develop sexual problems, the most common being erectile failure. (ox.ac.uk)
  • Non-small cell lung cancer (NSCLC) is one of the most common types of lung cancer, representing up to 84% of diagnoses. (santaclara.com)
  • Liver cancer is the fourth most frequent cause of cancer death worldwide and hepatocellular carcinoma (HCC), the most common type of liver cancer, is the fastest rising cause of cancer-related death in the United States. (bms.com)
Mechanisms1
  • This paper highlights the underlying pharmacological mechanisms of the anti-diabetic effects of ginsenosides. (frontiersin.org)