Outbreaks of serratia marcescens. Medical search. Frequent questions

Since many nosocomial infections are caused by multiply antibiotic-resistant strains of S. marcescens, this increases the danger to hospitalized patients, and hospital personnel should be vigilant in preventing nosocomial outbreaks due to this organism. (scienceopen.com)
100% of Serratia marcescens strains isolated produced enzymes ESBL (Extended Spectrum Betalactamases), AMPc (Cyclic Adenosinemonophosphate) and NDM (New Delhi Metallobetalactamase), causing resistance to the antibiotics Levofloxacin, Tygeciclina and Amikacin. (outbreaknewstoday.com)
Some strains of S marcescens are capable of producing a pigment called prodigiosin, which ranges in color from dark red to pale pink, depending on the age of the colonies. (medscape.com)
Serological typing has also been used and this method seems to be a suitable first-line typing method for S. marcescens , although some strains remain untypable. (microbiologyresearch.org)
In the most recent outbreak, 11 patients were infected with multi-resistant Acinetobacter strains and 26 patients were colonised. (microbiologyresearch.org)
In this collection are preserved approximately 8,000 strains of bacteria representing 30 distinct species among the most frequently cited: Methicillin Resistant Staphylococcus aureus (MRSA), Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii, Enterobacter cloacae, Entrobacter aerogenes and Serratia marcescens, isolated form cases of septicemia, meningitis, penumonias among others. (specieslink.net)

We describe an outbreak of Serratia marcescens ( S. marcescens ) infection in the neonatal intensive care unit at Women's Hospital in Sinaloa, Mexico. (scienceopen.com)
In April 2021, an outbreak of S. marcescens infection was identified. (scienceopen.com)
S. marcescens has a long and interesting taxonomic, medical experimentation, military experimentation, and human clinical infection history. (scienceopen.com)
While S. marcescens is a rare cause of community-acquired infections, it has emerged as an important nosocomial healthcare-associated pathogen and a frequent source of outbreaks of hospital infection, in both adult and pediatric patients. (outbreaknewstoday.com)
S. marcescens is implicated in a wide range of serious infections including pneumonia, lower respiratory tract infection, urinary tract infection, bloodstream infection, wound infection and meningitis. (outbreaknewstoday.com)
Serratia infection is responsible for about 2% of nosocomial infections of the bloodstream, lower respiratory tract, urinary tract, surgical wounds, and skin and soft tissues in adult patients. (medscape.com)
Serratia infection has caused endocarditis and osteomyelitis in people addicted to heroin. (medscape.com)
the remaining 12 patients had infection with a nonmarcescens Serratia species. (medscape.com)
Although used in hopes of reducing the likelihood of infection in patients, many products have been identified as the source of infection in several outbreaks, sometimes due to the nonsterile nature of the many readily available antiseptics. (biomedcentral.com)
In research laboratories employing Drosophila fruit flies, infection of them with S. marcescens is common. (wikipedia.org)
A rare clinical form of gastroenteritis occurring in early infancy caused by infection with S. marcescens. (wikipedia.org)
Over the last 30 years, Serratia marcescens has become an important cause of nosocomial infection. (microbiologyresearch.org)
Pigment (prodigiosin) biosynthesis by S. marcescens has been investigated fully since the emergence of the organism as a cause of infection. (microbiologyresearch.org)
Antibiotics used to treat serratia infection include β-lactam agents, aminoglycosides and fluoroquinolones and a variety of different resistance mechanisms have been demonstrated. (microbiologyresearch.org)
RAPD-PCR has also been applied to a small number of isolates and seems to be a promising method, especially for rapid monitoring of an outbreak and tracing the source of initial infection. (microbiologyresearch.org)
Continued surveillance of ITU patients and occasional environmental sampling has proved to be important in preventing and controlling subsequent outbreaks of infection by this increasingly important nosocomial pathogen. (microbiologyresearch.org)
Three weeks later, the 75-year-old retired pipe fitter was dead, the victim of what doctors said was an infection of the bacterium Serratia marcescens. (sweetliberty.org)
One gentlemen, recovering from prostate surgery, developed complications of heart infection as Serratia colonized his heart valves. (eekim.com)
Infection with Serratia was so rare that the outbreak was extensively investigated by the University to identify the origins of this scarlet letter bug. (eekim.com)

Enterobacterales (including multidrug-resistant Enterobacter cloacae , Klebsiella pneumoniae , and Serratia marcescens ) and non-fermentative Gram-negative rods were found in 5 and 7 outbreaks and in 34.1% and 42.6% of 164 isolates , respectively, from cross-sectional surveys. (itg.be)

The Alabama Department of Public Health announced an ongoing investigation of an outbreak of Serratia marcescens bacteremia in six Alabama hospitals. (drugs.com)
The yearly incidence of Serratia bacteremia is 1.03 per 100,000 population, with 47% of episodes having their onset in the community. (medscape.com)
In a population-based study of Serratia bacteremia, the 7-day and 6-month mortality rates were 5% and 37%, respectively. (medscape.com)
S. marcescens is commonly involved in hospital-acquired infections (HAIs), also called nosocomial infections, particularly catheter-associated bacteremia, urinary tract infections, and wound infections, and is responsible for 1.4% of HAI cases in the United States. (wikipedia.org)
Outbreak of Acinetobacter baumannii Bacteremia Related. (cambridge.org)
Sikka MK, Hayden MK, Pur S, Segreti J, Harris AA, Weinstein RA, Trenholme G. Microbiologic and clinical epidemiologic characteristics of the Chicago subset of a multistate outbreak of Serratia marcescens bacteremia. (rush.edu)

Serratia species appear to be common environmental organisms, and this helps to explain the large number of nosocomial infections due to these bacteria. (scienceopen.com)
Serratia species are opportunistic gram-negative bacteria in the large family, Enterobacteriaceae. (medscape.com)
The prevalence of Serratia species as a cause of nosocomial infections is diminishing, but these bacteria are still able to cause hospital outbreaks, especially in intensive care units. (medscape.com)
Serratia marcescens (/səˈreɪʃiə mɑːrˈsɛsɪnz/)[failed verification] is a species of rod-shaped, Gram-negative bacteria in the family Yersiniaceae. (wikipedia.org)
The U.S. Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) are investigating an outbreak of the deadly serratia marcescens bacteria in six Alabama hospitals. (californiainjuryblog.com)
In 80 of those experiments, the Army said it used live bacteria that its researchers at the time thought were harmless, such as the Serratia that was showered on San Francisco. (sweetliberty.org)
Operation Sea-Spray was a 1950 U.S. Navy secret biological warfare experiment in which Serratia marcescens and Bacillus globigii bacteria were sprayed over the San Francisco Bay Area in California , in order to determine how vulnerable a city like San Francisco may be to a bioweapon attack. (liveactioneating.com)
Another type of red bacteria is called Serratia marcescens. (longboardgrip.com)
This type of algae is actually a bacteria known as Serratia marcescens. (longboardgrip.com)

We describe an outbreak infections (Appendix Table 1, https://wwwnc.cdc. (cdc.gov)
Serratia infections: from military experiments to current practice. (scienceopen.com)
S. marcescens and S. liquefaciens have been isolated as causative agents of numerous outbreaks and opportunistic infections, and the association of these organisms with point sources such as medical devices and various solutions given to hospitalized patients is striking. (scienceopen.com)
An outbreak of S marcescens bloodstream infections was identified in patients receiving contaminated bags of parenteral nutrition. (medscape.com)
[ 15 ] Outbreaks of S marcescens meningitis , wound infections, and arthritis have occurred in pediatric wards. (medscape.com)
Serratia species are responsible for 1.4% of nosocomial bloodstream infections. (medscape.com)
Serratia marcescens pulmonary infections in a cardiothoracic intensive care unit. (germitec.com)
An outbreak of Pseudomonas aeruginosa respiratory tract infections associated with intrinsically contaminated ultrasound transmission gel. (germitec.com)
RÉSUMÉ L'émergence et la propagation rapide des souches de Klebsiella pneumoniae résistantes aux antibiotiques et porteuses du gène blaKPC codant la production de carbapénèmases ont compliqué la prise en charge des infections des patients. (who.int)

Venezuelan regional newspaper, El Impulso reported this week in an investigative report (computer translated) , an outbreak of the bacterium, Serratia marcescens among children admitted at Agustín Zubillaga Pediatric Hospital in Barquisimeto, Lara state, in northwestern Venezuela. (outbreaknewstoday.com)
In 1819, Bartolomeo Bizio, a pharmacist from Padua, Italy, discovered and named S marcescens when he identified the bacterium as the cause of a miraculous bloody discoloration in a cornmeal mush called polenta. (medscape.com)
Since 1906, physicians have used S marcescens as a biological marker for studying the transmission of microorganisms because, until the 1950s, this bacterium was generally considered a harmless saprophyte. (medscape.com)
Though the source of this unusual organism could not be located despite an exhaustive epidemiological search, Stanford published a report on the outbreak, noting that "the isolation of a red pigment-producing bacterium from the urine of human beings was of interest, at first, as a curious clinical observation. (eekim.com)

in 2 hospitals in Florida, USA, of S. marcescens pro- gov/EID/article/26/11/20-2203-App1.pdf), all pos- ducing Klebsiella pneumoniae carbapenemase (KPC). (cdc.gov)

S. marcescens and S. liquefaciens are usually identified well in the clinical laboratory, but the other species are rare enough that laboratory technologists may not recognize them. (scienceopen.com)

Because S. marcescens was thought to be a nonpathogen and is usually red pigmented, the U.S. military conducted experiments that attempted to ascertain the spread of this organism released over large areas. (scienceopen.com)
S. marcescens is a motile organism and can grow in temperatures ranging from 5-40 °C and in pH levels ranging from 5 to 9. (wikipedia.org)
regions that provide an important reservoir for the organism in between outbreaks of the disease. (up.ac.za)

PathoSPOT genomic epidemiology reveals under-the-radar nosocomial outbreaks. (cdc.gov)

According to the website, antimicrobe.org, Serratia marcescens is an opportunistic pathogen whose clinical significance has been appreciated only in the last four decades. (outbreaknewstoday.com)
Only since the 1960s has S marcescens been recognized as an opportunistic pathogen in humans. (medscape.com)

Due to this, and because S. marcescens produces a reddish-orange tripyrrole dye called prodigiosin, it may cause staining of the teeth. (wikipedia.org)
The biochemical pathway for the production of prodigiosin by S. marcescens has been characterized by analyzing what intermediates become accumulated in specific mutants. (wikipedia.org)

Serratia species cause less than 6% of cases of hospital-acquired bacterial pneumonia. (medscape.com)
[ 9 ] Alternatively, other non-necrotizing gram-negative bacilli (eg, Serratia marcescens) may be responsible for nosocomial pneumonia. (medscape.com)
[5] Cases of pneumonia in San Francisco also increased after Serratia marcescens was released, though a causal relation has not been conclusively established. (liveactioneating.com)

Serratia meningitis and Serratia endocarditis carry a high mortality rate. (medscape.com)
Alexander R. H. , Reichenbach D. D. , Merendino K. A. Serratia marcescens endocarditis: a review of the literature and report of a case involving a homograft replacement of the aortic valve. (microbiologyresearch.org)
Körner R. J. , Nicol A. , Reeves D. S. , MacGowan A. P. , Hows J. Ciprofloxacin resistant Serratia marcescens endocarditis as a complication of non-Hodgkin's lymphoma. (microbiologyresearch.org)
Mills J. , Drew D. Serratia marcescens endocarditis: a regional illness associated with intravenous drug abuse. (microbiologyresearch.org)

Harmonization of whole-genome sequencing for outbreak surveillance of Enterobacteriaceae and Enterococci. (applied-maths.com)
Molecular and microbiological report of a hospital outbreak of NDM-1-carrying Enterobacteriaceae in Mexico. (ac.ir)

Bizio named Serratia in honor of an Italian physicist named Serrati, who invented the steamboat, and Bizio chose marcescens (from the Latin word for decaying) because the bloody pigment was found to deteriorate quickly. (medscape.com)

Typing methods used to study the epidemiology of S. marcescens include biotyping, bacteriocin typing, phage typing, plasmid analysis, polymerase chain reaction amplification of enterobacterial repetitive intergenic consensus sequences (ERIC-PCR) and ribotyping. (microbiologyresearch.org)

An outbreak of meningitis caused by S marcescens in patients who had undergone spinal anaesthesia for caesarean section has been ascribed to contaminated medications used for this purpose. (medscape.com)

In Senate subcommittee hearings in 1977, the U.S. Army revealed that weeks before Mr. Nevin sickened and died, the Army had staged a mock biological attack on San Francisco, secretly spraying the city with Serratia and other agents thought to be harmless. (sweetliberty.org)
Except that Serratia marcescens isn't harmless. (eekim.com)

S. marcescens was isolated from the blood cultures of 15 neonates with clinical signs of neonatal sepsis. (scienceopen.com)
Outbreaks of serratia marcescens bacteriuria in a neurosurgical intensive care unit of a tertiary care teaching hospital: A clinical, epidemiologic, and laboratory perspective. (cdc.gov)
Clinical Perspectives in Integrating Whole Genome Sequencing into the Investigation of Healthcare and Public Health Outbreaks - Hype or Help? (cdc.gov)

Serratia species, in particular Serratia marcescens, are significant human pathogens. (scienceopen.com)

The findings highlight the need for hospitals to implement strict hygiene measures, especially regarding hand washing, to prevent future outbreaks. (scienceopen.com)
have occurred in Nottingham hospitals since at least 1977, punctuated by more prolonged outbreaks involving larger numbers of patients, particularly those confined to the intensive therapy unit (ITU) with severe underlying disease. (microbiologyresearch.org)

In addition to seasonal endemic viruses, emerging and re-emerging virus outbreaks such as severe acute respiratory syndrome and Middle East respiratory syndrome coronaviruses (SARS-CoV and MERS-CoV) require close contact for human-to-human transmission and can spread nosocomially [ 5 , 6 ]. (springer.com)

S. marcescens, and probably other species in the genus, carries several antibiotic resistance determinants and is also capable of acquiring resistance genes. (scienceopen.com)
16S rRNA gene sequencing may enable better identification of some of the less common Serratia species. (scienceopen.com)
Serratia marcescens is the primary pathogenic species of Serratia . (medscape.com)
[ 14 ] In the hospital, Serratia species tend to colonize the respiratory and urinary tracts, rather than the gastrointestinal tract, in adults. (medscape.com)

Outbreak of vanB vancomycin-resistant Enterococcus faecium colonization in a neonatal service. (monashhealth.org)

It appears that at least some Serratia isolates interfere with macrophage function or viability. (medscape.com)
Genomic and Phenotypic Characterisation of Campylobacter jejuni Isolates From a Waterborne Outbreak. (cdc.gov)

We conducted two reviews of healthcare-associated outbreaks and cross-sectional surveys related to the contamination of antiseptics, disinfectants, and hand hygiene products in healthcare settings: a scoping review on high-income countries and a systematic review on low- and middle-income countries. (itg.be)

The benefits of whole genome sequencing for foodborne outbreak investigation from the perspective of a National Reference Laboratory in a smaller country. (applied-maths.com)

From 1977 onwards, 13 outbreaks and 25 cross-sectional surveys were found: 20 from Asia and 13 from Africa. (itg.be)

The production of different enzymes by S. marcescens as virulence factors has also been reported, including chitinase, lipase, chloroperoxidase and an extracellular protein, HasA. (microbiologyresearch.org)

S. marcescens was found to be a certain human pathogen by the mid-1960s. (scienceopen.com)

In September 1950, the U.S. Navy sprayed a cloud of the microbe, Serratia marcescens into the air two-miles off the coast of San Francisco in order to see how susceptible we might be to germ warfare. (eekim.com)

A case was identified as any patient who tested positive for S. marcescens and showed signs of an infectious process. (scienceopen.com)
Outbreak News Today is an online blog magazine which focuses on news and information about infectious diseases and outbreaks. (outbreaknewstoday.com)

Outbreaks can, however, be quickly and effectively controlled with preventive strategies based upon early accurate viral diagnosis, knowledge of the current epidemiological season and effective hygiene practices to decrease the risk of transmission [ 8 ]. (springer.com)

Due to its abundant presence in the environment, and its preference for damp conditions, S. marcescens is commonly found growing in bathrooms (especially on tile grout, shower corners, toilet water lines, and basins), where it manifests as a pink, pink-orange, or orange discoloration and slimy film feeding off phosphorus-containing materials or fatty substances such as soap and shampoo residue. (wikipedia.org)

Investigation of a nosocomial outbreak of severe acute respiratory syndrome (SARS) in Toronto, Canada. (cdc.gov)
Analysis of the global population structure of Paenibacillus larvae and outbreak investigation of American foulbrood using a stable wgMLST scheme. (applied-maths.com)

S. marcescens are unusual. (cdc.gov)
The urinary tract outbreak was so unusual that the Stanford doctors wrote it up for a medical journal. (liveactioneating.com)

The Twitter thread below links these experiments to subsequent influenza outbreaks which, of course, led to mass vaccination programmes. (expose-news.com)

Recent virus epidemics and rising antibiotic resistance highlight the importance of hygiene measures to prevent and control outbreaks. (springer.com)

All patients admitted hospital health system network in Miami, Florida, from the source LTCF were placed in contact precau- identified an increase of CP- S. marcescens . (cdc.gov)
Cases of Serratia septic arthritis have been reported in patients receiving intra-articular injections, individuals with joint trauma, and patients with intravascular devices or who are undergoing intravascular procedures. (medscape.com)
The outbreak was controlled ultimately by transfer of infected or colonised patients to an isolation cubicle, cohort nursing, emphasis on the importance of hand washing before and after patient contact and when handling case notes, and the use of disposable aprons and gowns during patient contact. (microbiologyresearch.org)

In elkhorn coral, S. marcescens is the cause of the disease known as white pox disease. (wikipedia.org)
S. marcescens causes cucurbit yellow vine disease, leading to sometimes serious losses in melon fields. (wikipedia.org)
A Nationwide Outbreak of Invasive Pneumococcal Disease in Israel Caused by Streptococcus Pneumoniae Serotype 2. (cdc.gov)

S. marcescens may also be found in environments such as dirt and the subgingival biofilm of teeth. (wikipedia.org)

This will help prevent future outbreaks of rust colored algae. (longboardgrip.com)

[ 7 ] Serratia are capable of thriving in diverse environments, including water, soil, and the digestive tracts of various animals. (medscape.com)

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