• Because this type of cancer is relatively rare, it is best for a patient to seek surgical treatment from a high-volume cancer center with orthopaedic surgeons who specialize in treating osteosarcoma. (moffitt.org)
  • Routine follow-up is needed to rule out local recurrence or the appearance of metastasis, even though these are rare in parosteal osteosarcoma. (medscape.com)
  • APEX1 gene amplification and its protein overexpression in osteosarcoma: correlation with recurrence, metastasis, and survival. (medscape.com)
  • Osteosarcoma of the thoracic spine developed in a 15-year-old Japanese boy, After his first admission with paralysis, multiple skeletal metastases were demonstrated in the absence of pulmonary metastasis. (springer.com)
  • Biopsies - If an imaging test suggests the presence of an osteosarcoma, a physician can perform a core needle biopsy, fine needle aspiration biopsy or surgical biopsy to remove a small sample of tumor cells and tissue. (moffitt.org)
  • Osteosarcoma is a type of cancer in which tumor cells produce immature bone known as osteoid. (aaos.org)
  • Although osteosarcoma may appear to be in only one location in the lower leg or forearm, almost all patients have tumor cells called micrometastases in the lungs. (mdanderson.org)
  • The tumor cells in osteosarcoma work in a similar fashion to osteoblasts, but the bone created by the cancerous cells is much weaker and not fully formed. (spineuniverse.com)
  • At Moffitt Cancer Center, we offer prompt, individualized treatment for adults and teenagers with osteosarcoma. (moffitt.org)
  • New work by University of Colorado Cancer Center members at Colorado State University Flint Animal Cancer Center presented at the American Association for Cancer Research (AACR) Annual Meeting 2015 demonstrates a gene expression model that predicts canine osteosarcoma response to doxorubicin, potentially allowing veterinary oncologists to better choose which drug to use with their patients. (medicalnewstoday.com)
  • This is a cool thing for us, showing that we can use human models in canine cancer , and hinting that the reverse might also be true: the lessons we learn from canine osteosarcoma may help us better understand the human disease," says Daniel L. Gustafson, PhD, CU Cancer Center investigator and director for basic research at the Flint Animal Cancer Center. (medicalnewstoday.com)
  • If you'd like to explore treatment options for osteosarcoma, including surgery, the experts at Moffitt can answer your questions and recommend an individualized treatment plan for you. (moffitt.org)
  • Referrals are not required to receive osteosarcoma treatment at Moffitt. (moffitt.org)
  • While many osteosarcomas appear osteoblastic (meaning that they make new bone) on x-ray, less common findings include lesions that appear osteolytic (meaning that they break down bone), or mixed osteolytic/osteoblastic. (aaos.org)
  • The SEER database tracks 5-year relative survival rates for osteosarcoma in the United States, based on how far the cancer has spread. (cancer.org)
  • This rare condition may possibly be considered as a unicentric osteosarcoma with bone metastases, since there were no precursor lesions or history of exposure to radio-active materials or chemical agents. (springer.com)
  • More than half of osteosarcomas develop in people between the ages of 10 and 20, usually during a growth spurt. (drugs.com)
  • Microarray analysis identifies distinct gene expression profiles associated with histological subtype in human osteosarcoma. (medscape.com)