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  • tumors
  • Furthermore, the measurement of osteopontin in the blood or tumors of patients with cancer, as a way of providing valuable prognostic information, will be discussed based on emerging clinical data. (lu.se)
  • stimulates
  • Binding of osteopontin to these cell surface receptors stimulates cell adhesion, migration, and specific signaling functions. (lu.se)
  • assay
  • The recovery of Osteopontin spiked to three different levels throughout the range of the assay in various matrices was evaluated. (rndsystems.com)
  • therapeutic
  • Therefore, suppression of the action of osteopontin may confer significant therapeutic activity, and several strategies for bringing about this suppression have been identified. (lu.se)
  • Moreover
  • Moreover, osteopontin is present in elevated levels in the blood and plasma of some patients with metastatic cancers. (lu.se)
  • cancer
  • This review looks at the recent advances in understanding the possible mechanisms by which osteopontin may contribute functionally to malignancy, particularly in breast cancer. (lu.se)