The term SAPHO (an acronym for synovitis, acne, pustulosis, hyperostosis, osteitis) was coined in 1987 to represent this spectrum of inflammatory bone disorders that may or may not be associated with dermatologic pathology. (wikipedia.org)
Imaging findings in patients with a combination of synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) are often misinterpreted as discitis/osteomyelitis or metastases, resulting in multiple biopsies and delayed diagnosis. (ajnr.org)
SAPHO was proposed to refer to a combination of synovitis, acne, pustulosis, hyperostosis, and osteitis as a heading for these syndromes. (ajnr.org)
Beretta-Piccoli BC et al (2000) Synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome in childhood: a report of ten cases and review of the literature. (springer.com)
Psoriatic rheumatism and a related new entity, SAPHO, synovitis-acne-pustulosis-hyperostosis-osteitis syndrome]. (globale-dermatologie.com)
Moreover, different extra-articular manifestations, such as uveitis inflammatory bowel disease, celiac disease, Synovitis Acne Pustulosis HyperostosisOsteitis (SAPHO) syndrome or less common cardiac and/or pulmonary involvement may encompass jSPA spectrum. (frontiersin.org)
Syndrome of synovitis acne pustulosis hyperostosisosteitis (SAPHO) and chronic recurrent multifocal osteomyelitis (CRMO) present two diseases of a dermatologic and rheumatologic spectrum that are variable in manifestation und therapeutic response. (biomedcentral.com)
Therefore, we aimed to clinically characterize a patient group with syndrome of synovitis acne pustulosis hyperostosisosteitis (SAPHO) ( n = 47) and chronic recurrent multifocal osteomyelitis (CRMO)/ chronic non-bacterial osteomyelitis (CNO) ( n = 9) and analyze a CRMO candidate gene. (biomedcentral.com)
OBJECTIVE: This study aimed to analyse the radiological characteristics and clinical diversity of Japanese patients with synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome, a heterogeneous disorder. (bvsalud.org)
CONCLUSION: Sternoclavicular hyperostosis and pustulosis are frequently observed in patients with SAPHO syndrome. (bvsalud.org)
DIRA has similar cutaneous and systemic features as infantile pustular psoriasis and SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome. (exploremyplan.com)
SAPHO syndrome (acronym for Synovitis, Acne, Pustulosis, Hyperostosis and Osteitis) is considered to be a rare disorder, though its actual occurrence is probably underreported. (lomibaorheumatology.com)
Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) syndrome is a rare disease with most available data derived from case reports and few case series. (cjdiagnosis.com)
however, osteitis with hyperostosis is considered as a pathognomonic lesion of SAPHO syndrome [ 3 ]. (biomedcentral.com)
Current hypotheses in SAPHO suggest a genetic predisposition in combination with a bacterial infection, resulting in reactive osteitis [ 3 , 13 ]. (biomedcentral.com)
Sternocostoclavicular hyperostosis4
Since then, a number of associations between skin conditions and osteoarticular disorders have been reported under a variety of names, including sternocostoclavicular hyperostosis, pustulotic arthro-osteitis, and acne-associated spondyloarthropathy. (wikipedia.org)
Synthesis of 13 personal observations of sternocostoclavicular hyperostosis and 300 cases from the literature. (springer.com)
Freyschmidt J et al (1998) The bullhead sign: scintigraphic pattern of sternocostoclavicular hyperostosis and pustulotic arthroosteitis. (springer.com)
Underlying aetiologies include osteoarthritis of the sternoclavicular joint, condensing osteitis, spontaneous dislocation of the sternoclavicular joint, and sternocostoclavicular hyperostosis. (wren-clothing.com)
Biological agents were more frequently used in patients with peripheral osteitis and arthritis. (bvsalud.org)
Vertebral1
Findings of spinal involvement on conventional radiographic imaging have been reported to include vertebral body osteosclerosis, paravertebral ligament ossification, hyperostosis, and discovertebral junction lesions. (ajnr.org)
Multifocal1
Osteitis can manifest itself as spondyloarthropathy, spondylodiscitis, chronic recurrent multifocal osteomyelitis, or pustular arthroosteitis. (medicinelearners.com)
Bone3
Anterior chest wall (most common site, 65-90% of patients):[citation needed] Hyperostosis, sclerosis and bone hypertrophy especially involving the sternoclavicular joint, often with a soft tissue component. (wikipedia.org)
Moreover, it can present as a sclerosing osteitis originating from the bone marrow, a hyperostosis with increased bone cuff formed by the periost, an ossification of ligaments, accompanied by osteolysis or an erosion of a joint. (biomedcentral.com)
CECT revealed cortical bone erosions of the right temporal squama and condyle with diffuse endosteal sclerosis and hyperostosis of the mandibular condyle and ramus. (archintsurg.org)
Primarily1
Hyperostosis occurs primarily in the sternoclavicular joint. (medicinelearners.com)
Findings1
According to recent findings, autoinflammatory nonbacterial osteitis is more probable in immunecompetent patients in good general condition and should always be considered as a differential diagnosis. (springer.com)
Patients1
Peripheral aseptic osteitis was observed in 22 patients, and the tibia was involved in 12. (bvsalud.org)
Shows2
This graph shows the total number of publications written about "Osteitis" by people in this website by year, and whether "Osteitis" was a major or minor topic of these publications. (uchicago.edu)
Cranium 5 also shows an extensive maxillary osteitis associated with a dental apical abscess, as well as another dental apical abscess in its mandible. (usf.edu)
Acne1
Since then, a number of associations between skin conditions and osteoarticular disorders have been reported under a variety of names, including sternocostoclavicular hyperostosis, pustulotic arthro-osteitis, and acne-associated spondyloarthropathy. (wikipedia.org)
Osteomyelitis1
Inflammation of the bone (osteomyelitis, osteitis) is uncommon in the B6C3F1/N mouse and F344/N rat. (nih.gov)
Fibrosa cystica3
Osteitis fibrosa cystica of the tibia. (mdwiki.org)
Osteitis fibrosa cystica is defined as the classic skeletal manifestation of advanced hyperparathyroidism . (mdwiki.org)
Osteitis fibrosa cystica is the result of unchecked hyperparathyroidism, or the overactivity of the parathyroid glands , which results in an overproduction of parathyroid hormone (PTH). (mdwiki.org)
Bone hypertrophy1
Anterior chest wall (most common site, 65-90% of patients):[citation needed] Hyperostosis, sclerosis and bone hypertrophy especially involving the sternoclavicular joint, often with a soft tissue component. (wikipedia.org)
Lesions1
Findings of spinal involvement on conventional radiographic imaging have been reported to include vertebral body osteosclerosis, paravertebral ligament ossification, hyperostosis, and discovertebral junction lesions. (ajnr.org)
Cutaneous1
furthermore, our patient has an isolated osteitis lesion, without cutaneous lesion. (biomedcentral.com)
Inflammation2
Histopathological features of acute inflammation are well described: studies from intervertebral discs 5 , femoral heads 6 , 7 , sacroiliac joints 8 , 9 , manubriosternal junction 10 , and zygapophyseal joints 11 , 12 suggest that subchondral inflammation at the interface between bone and cartilage - a subchondral osteitis - is the primary site of the AS immunopathology. (jrheum.org)
MRI of the pelvis with T1 sequences is used for evaluation of ankylosis, erosions, backfill, and fatty metaplasia, and short T1 inversion recovery sequences are used for evaluation of osteitis/inflammation. (medscape.com)
Infantile cortical hyperostosis (ICH, OMIM 114000) is a rare familial disorder which affects infants. (nih.gov)
Result1
It is thought to be caused by infection with low-toxicity bacteria and to be the result of reactive infectious osteitis. (e-jyms.org)
Include1
General indicators of stress among the individuals observed include healed periostitis (n=8), porotic hyperostosis (n=5), and linear enamel hypoplasias (n=8). (illinois.edu)