Ahmad P, Abdel Latef AA, Hashem A, Abd_Allah EF, Gucel S, Tran L-SP (2016) Nitric oxide mitigates salt stress by regulating levels of osmolytes and antioxidant enzymes in chickpea. (vegetosindia.org)
Trimethylamine2
It is currently the consensus belief that protective osmolytes such as trimethylamine N-oxide (TMAO) favor protein folding by being excluded from the vicinity of a protein, whereas denaturing osmolytes such as urea lead to protein unfolding by strongly binding to the surface. (ibpc.fr)
the peptides N -acetyl-glycine- N -methylamide and N -acetyl-leucine- N -methylamide, and the osmolytes trimethylamine N -oxide and tetramethylurea. (lu.se)
Amino acids3
These studies demonstrated that a combination of three different osmolytes including sugar, sugar alcohol and amino acids/proteins could stabilize Jurkat cells and mesenchymal stromal cells (MSCs) during freezing. (nature.com)
The significant improvement in the osmolytes ( proteins and amino acids ), and enzymatic antioxidative defense system enhanced the membrane stability and mitigated the damaging effects of Cd. (bvsalud.org)
These positive responses owed to increase the osmolytes level (proline, free amino acids, and soluble sugars) and antioxidative compounds (non-enzymatic concentration, enzymatic activities, phenolic acid, and carotenoids). (uaeu.ac.ae)
Concentrations5
In the present study, ex vivo high-resolution 1H-NMR spectroscopy was used to investigate the effects of ALF, with or without superimposed hypothermia, on brain organic osmolyte concentrations in relation to the severity of encephalopathy and brain edema in rats with ALF due to hepatic devascularization. (nih.gov)
This study was conducted to test the hypothesis that malt osmolyte concentrations can be used as an indicator of barley malt quality. (usda.gov)
Osmolyte concentrations increased most rapidly in days 1 through 3 of germination. (usda.gov)
After 4 days osmolyte concentrations began to plateau. (usda.gov)
However, some bacteria have found ways to import molecules that increase solute concentrations inside the cell and grow despite high osmolyte concentrations in the environment. (rug.nl)
Proteins4
Osmolytes play an integral part in maintaining proteins balance and mediating macromolecular relationships inside the intracellular environment from the cell. (biotech-angels.com)
Generally such dehydration of molecular areas favorably correlates with the power of several osmolytes to market folding of proteins and augment proteins balance through their unfavorable relationships using the unfolded condition (13-17). (biotech-angels.com)
Nevertheless destabilizing ramifications of osmolytes on proteins structure are also recently mentioned (18-21). (biotech-angels.com)
This increases the osmolyte concentration inside the cells without compromising the structure of proteins. (rug.nl)
Organic5
Osmolytes are low-molecular-weight organic compounds that influence the properties of biological fluids. (wikipedia.org)
Osmolytes are a class of organic molecules that play a significant role in regulating osmotic pressure and maintaining cellular homeostasis in various organisms, particularly in response to environmental stressors. (wikipedia.org)
These findings demonstrate that experimental ALF results in selective changes in brain organic osmolytes as a function of the degree of encephalopathy which are associated with brain edema, and provides a further rationale for the continued use of hypothermia in the management of this condition. (nih.gov)
Keywords: Protein-DNA thermodynamics Osmotic tension Conformational equilibrium Molecular dynamics Intro Osmolytes are little organic substances that are normally discovered within the intracellular environment of living microorganisms where they exert protecting functions against intense environmental circumstances and osmotic tension (1). (biotech-angels.com)
Alleviation of cadmium toxicity in Zea mays L. through up-regulation of growth, antioxidant defense system and organic osmolytes under calcium supplementation. (bvsalud.org)
Accumulation1
Drought-induced osmolyte accumulation and strong enzymatic and non-enzymatic defense systems prevented the severe damage in Dong Dan 80. (edu.au)
Efflux1
When a cell swells due to external osmotic pressure, membrane channels open and allow efflux of osmolytes carrying water, restoring normal cell volume. (wikipedia.org)
Enzymes1
The up-regulation of antioxidant enzymes as well as proline (osmolyte) triggered by 24-epibrassinolide could have conferred tolerance to the Ni-stressed plants resulting in improved growth, nodulation and yield attributes. (uaeu.ac.ae)
Stabilize2
Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states. (expasy.org)
Consequently the power of osmolytes to favorably connect to the unliganded conformation in order to stabilize it might take into account the negative aftereffect of osmotic tension on EGR1-DNA discussion observed here. (biotech-angels.com)
Renal2
In humans, osmolytes are of particular importance in the renal medulla. (wikipedia.org)
It is one of the major osmolyte in the renal medullary cells. (ebi.ac.uk)
Therapeutic Nutrition1
OSMOLITE 1.2 CAL is high-protein therapeutic nutrition that provides complete, balanced nutrition for long- or short-term tube-feeding for patients who may benefit from increased protein and calories. (fostermedical.com)
Glycine1
OpuA is special because it can import glycinebetaine in huge amounts, leading to a very high internal osmolyte concentration. (rug.nl)
Osmotic2
Osmolytes help cells adapt to changing osmotic conditions, thereby ensuring their survival and functionality. (wikipedia.org)
Bacteria accumulate osmolytes for protection against a high osmotic environment. (wikipedia.org)
Protective1
Osmolytes are protective molecules that can have antioxydant, anti-inflammatory or are thought to be useful for neurodegenerative diseases or even cancer. (substack.com)
Nutrition2
Osmolite® HP is a 1.0kcal/ml complete, balanced, high-protein liquid nutrition. (abbottnutrition.ie)
Osmolite Ready to Use Oral Supplement is a source of Complete, Balanced Nutrition and a low-residue formula for tube-fed patients with increased calorie and protein needs, or for those with limited volume tolerance. (medicaleshop.com)
Enzymatic1
Moreover osmolytes will also be thought to displace drinking water from interacting areas binding clefts energetic sites and additional cavities found within macromolecules and by doing this help ligand binding to protein and enhance enzymatic activity. (biotech-angels.com)
Protein Stability2
2018. The Osmolyte TMAO Modulates Protein Folding Cooperativity by Altering Global Protein Stability. . (ncbs.res.in)
The two investigated osmolytes have opposite effects on protein stability but have virtually the same effect on water dynamics, suggesting that they do not act indirectly via solvent perturbations. (lu.se)
Soluble1
At intervals of 24 h over the steeping regime green malt from each cultivar was removed and tested for osmolyte concentration, malt extract(ME), diastatic power (DP), alpha-amylase activity, soluble/total protein (S/T), and beta-glucan concentration. (usda.gov)
Cells5
Osmolytes are present in the cells of fish, and function to protect the cells from water pressure. (wikipedia.org)
As the osmolyte concentration in fish cells scales linearly with pressure and therefore depth, osmolytes have been used to calculate the maximum depth where a fish can survive. (wikipedia.org)
Fish cells reach a maximum concentration of osmolytes at depths of approximately 26,900 feet (8,200 meters), with no fish ever being observed beyond 27,349 feet (8,336 meters). (wikipedia.org)
This study examined the post-thaw recovery of Jurkat cells cryopreserved in single osmolytesolutions containing sucrose, glycerol or isoleucine, as well as in a combination of the three osmolytes. (nature.com)
Post-thaw recovery of Jurkat cells in single osmolyte was low. (nature.com)
Formula2
OSMOLITE 1 Cal is a low residue formula for tube-feeding patients. (family.abbott)
Tube Feeding Formula Osmolite® 1.5 Cal 33.8 oz. (medexsupply.com)
Water1
The cover art for the November 19 issue of Biophysical Journal is an artistic representation of the molecular dynamic simulation of our model protein (α-synuclein) in water and in osmolytes viz. (biophysics.org)
Cell2
Osmolytes also interact with the constituents of the cell, e.g., they influence protein folding. (wikipedia.org)
The objective of this investigation is to understand in more detail the relationships amongst the osmolytes present in these solutions and Jurkat cell recovery. (nature.com)
Growth1
The prime approach for this therapy would be to infuse kosmotropic osmolytes by the intravenous route to improve the physiological conditions and promote the reduction of cancer growth with no side effects. (substack.com)
Test1
Statistical modeling was used to characterize the importance of each osmolyte in the combination and test for interactions between osmolytes. (nature.com)
Features1
In order to further our knowledge of the part of osmolytes in mediating macromolecular features we undertook today's study for the binding of human being EGR1 transcription element also called Zif268 to its cognate DNA. (biotech-angels.com)
Influence1
How osmolytes influence hydrophobic polymer conformations: A unified view from experiment and theory. (ibpc.fr)
Find1
Find similar words to osmolyte using the buttons below. (yourdictionary.com)
Results1
Results presented here from both experiment and simulation are in line with earlier predictions on a model Lennard-Jones polymer while also demonstrating the distinction in the mechanism of osmolyte action between protein and hydrophobic polymer. (ibpc.fr)
Solution1
Raman images clearly demonstrated that damaging intracellular ice formation was observed more often in the presence of single osmolytes as well as non-optimized multi-component solution compositions. (nature.com)