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  • neurotoxicity
  • A variety of organophosphorus (OP) compounds with and without delayed neurotoxicity were examined for inhibitory power against neurotoxic esterase (NTE) and acetylcholinesterase (AchE) of hen brain in vitro and in vivo. (eurekamag.com)
  • Delayed neurotoxicity induced by OP compounds correlated with high inhibition of NTE in vivo, but in vitro studies comparing I50 [median inhibitory concentration] for both enzymes did not provide a guide to evaluation of delayed neurotoxicity. (eurekamag.com)
  • The experiments described in this paper were designed to isolate [3H]di-isopropyl phosphorofluoridate-binding proteins by sodium dodecyl sulphate/polyacrylamide-gel electrophoresis for the purpose of characterizing and identifying potential initiation sites for organophosphorus-compound-induced delayed neurotoxicity. (cdc.gov)
  • The major Paraoxon-insensitive Mipafox-sensitive binding protein (Mr 160 000) was found to be identical with one previously identified as neurotoxic esterase, an enzyme that has been proposed to be the target site for organophosphorus-compound-induced delayed neurotoxicity. (cdc.gov)
  • organophosphate compounds
  • Most of the organohalogen and organophosphate compounds also do not react permanently to attach themselves into their surroundings but further work is now underway to graft further chemical groups onto these materials to enable them to become integrated without losing their retardant efficiency. (wikipedia.org)
  • toxicity
  • The fact that nobody knew anything about the toxicity of TEPP at this time was evidenced by De Clermont himself, who reported that he had tasted the compound out of curiosity. (wikipedia.org)
  • organophosphates
  • Such compounds include tris(2,3-dibromopropyl) phosphate (brominated tris) and chlorinated organophosphates such as tris(1,3-dichloro-2-propyl)phosphate (chlorinated tris or TDCPP) and tetrakis(2-chlorethyl)dichloroisopentyldiphosphate (V6). (wikipedia.org)
  • aryl
  • Both palladium and copper complexes of the compound exhibit high activity for the coupling of aryl halides and aryl tosylates with various amides. (wikipedia.org)
  • coordination
  • In a descriptive but only intermittently used nomenclature, phosphorus compounds are identified by their coordination number δ and their valency λ. (wikipedia.org)
  • Reminiscent of π-ligand exchange in coordination compounds, a phosphirenium ion may undergo alkyne exchange with other alkynes to give a mixture of phospinirenium species in equilibrium. (wikipedia.org)
  • Its variety of coordination geometries enable tert-butylphosphaacetylene to participate in several types of reactions, including 1,2-additions of halogenated compounds. (wikipedia.org)
  • phosphines
  • The addition of primary phosphines to unsaturated compounds has not yet been investigated systematically, and in the chemical literature there is information only about the cyanoethylatfon of phenylphosphine [1- (vdocuments.site)
  • exhibit
  • In comparison to other pharmacological approaches, the appeal of bioscavenger protection is that bioscavenger-protected survivors of exposure to OP compounds do not exhibit the postexposure incapacitation and toxic effects that are commonly observed with survivors protected by traditional antidotal approaches, such as oximes, anticholinergics, or carbamates (6). (springer.com)
  • Diphosphene compounds usually exhibit a symmetry-allowed ( π → π ∗ {\displaystyle \pi \rightarrow \pi ^{*}} ) (intense) and symmetry-forbidden electronic transitions ( n → π ∗ {\displaystyle n\rightarrow \pi ^{*}} ) (weak). (wikipedia.org)
  • addition
  • In continuation of the study of the addition of phenylphosphine to unsaturated compounds we have carried out the addition of phenylphosphine to allylamfne, allyl acetate, and 5-vinyl-2-picoline, and we also carried out the oxidation of all the addition products synthesized. (vdocuments.site)
  • activity
  • It is a toxic compound, due to its anticholinesterase activity, which not only applies to insects, but also to other animals. (wikipedia.org)
  • rapid
  • Novel and rapid method for determination of organophosphorus pesticide residues in edible fungus using direct gas purge microsyringe extraction coupled on-line with gas chromatography-mass spectrometry," Talanta , vol. 142, pp. 64-71, 2015. (hindawi.com)