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  • Neuroscience
  • At a neuroscience meeting, two teams of researchers will report implanting human brain organoids into the brains of lab rats and mice, raising the prospect that the organized, functional human tissue could develop further within a rodent. (statnews.com)
  • In the previously unreported experiments implanting human brain organoids into lab rodents, most of the transplants survived, in one case for at least two months, according to summaries of the two papers being presented at the annual meeting of the Society for Neuroscience in Washington, D.C. More notably, the human organoids implanted into mice connected to the rodent's circulatory system, making this the first reported vascularization. (statnews.com)
  • neurons
  • And mature neurons from the human brain organoid sent axons, the wires that carry electrical signals from one neuron to another, into "multiple regions of the host mouse brain," according to a team led by Fred "Rusty" Gage of the Salk Institute, one of the world's most eminent neurobiologists. (statnews.com)
  • grown
  • That is necessary if the organoids are to grow bigger, probably the only way they can mimic fully grown brains and show how disorders such as autism, epilepsy, and schizophrenia unfold. (statnews.com)
  • brains
  • The most advanced of these human brain organoids - no bigger than a lentil and, until now, existing only in test tubes - pulse with the kind of electrical activity that animates actual brains. (statnews.com)
  • These micro quasi-brains are revolutionizing research on human brain development and diseases from Alzheimer's to Zika , but the headlong rush to grow the most realistic, most highly developed brain organoids has thrown researchers into uncharted ethical waters. (statnews.com)
  • dish
  • Like virtually all experts in the field, neuroscientist Hongjun Song of the University of Pennsylvania doesn't "believe an organoid in a dish can think," he said, "but it's an issue we need to discuss. (statnews.com)
  • cells
  • Neither can regulation: Although the National Institutes of Health has a moratorium on funding research that puts human stem cells into the early embryos of vertebrates, there is no such ban on implanting human organoids, and virtually no one outside the labs conducting organoid research has enough of an idea about what's going on to, say, call for a commission to study what should and should not be allowed. (statnews.com)
  • brain
  • A human brain organoid cannot reach anything close to the size of even a child's brain in the tiny confines of a mouse's (which is one one-thousandth the volume of a person's brain), almost certainly limiting how complex it can become. (statnews.com)