Loading...
  • actin
  • Mechanistically, MZ dchs1b phenotypes can be explained in part by defective actin or microtubule networks, which appear bundled in mutants. (biologists.org)
  • In animals, Scar/WAVE family members activate Arp2/3 complex-dependent actin nucleation through interactions with Abi1, Nap1, PIR121, and HSCP300. (plantcell.org)
  • Pigment dispersion involves initial rapid microtubule-dependent transport to the periphery by Kinesin II and subsequent slow diffusion-like movement along the randomly arranged actin filaments. (uchc.edu)
  • Second, we have demonstrated that during dispersion the pigment granules that initially move along microtubules switch tracks and continue motion along randomly arranged actin filaments. (uchc.edu)
  • Thus, each pigment granule bears a member of each of the families of motor molecules: cytoplasmic dynein and a kinesin-like motors (specific for microtubules) and a myosin motor (specific for actin filaments). (uchc.edu)
  • kinetochores
  • Beyond yeast species, kinetochore clustering is also observed in the mitotic cells of Drosophila melanogaster , where kinetochores are present close to the nucleolus and play a significant role in heterochromatin organization ( 11 , 12 ). (asm.org)
  • mechanism
  • This mechanism is thought to rely on the activity of RanGTP, which induces liberation of microtubule nucleation factors sequestered in the complex with importins. (rupress.org)
  • Physiological functioning of Katanin and the resulting microtubule fragmentation is now reported to be important underlying mechanism in cell division, neuron development, cell migration, and locomotory organelle formation. (hindawi.com)
  • chromosome
  • Kinetochore clustering helps in the organization of yeast chromosomes in the Rabl configuration so that chromosome arms lie freely in the nucleoplasm ( 5 ). (asm.org)