• say that the Gabon assemblage is most likely fossilized colonial organisms, and are thus evidence of multicellular life. (creation.com)
  • However, these fossils would be considered unimportant if it wasn't for the age assigned to them and that they are called 'multicellular organisms' because of their size. (creation.com)
  • This ambiguity creates confusion: when people ordinarily think of multicellular organisms, they think of animals and plants (and fungi). (creation.com)
  • In this study, we used comparative transcriptomics to identify differentially expressed genes underlying cln5 -deficiency phenotypes during growth and the early stages of multicellular development. (frontiersin.org)
  • [7] The complex cell signaling pathways of multicellular organisms such as plants and humans can make understanding the mechanisms of this inherited process very difficult. (cloudfront.net)
  • Since their discovery in 1993, miRNAs have been described in all multicellular organisms and are associated with a vast breadth of biological functions, including cellular proliferation, cellular differentiation and immunity, as well as tissue remodeling and various human diseases, including cancer ( 4 ). (spandidos-publications.com)
  • It has been known for several decades that the pattern of distribution of methyl cytosines is not equal in all tissues in a multicellular organism and that it exhibits tissue specificity (Razin and Szyf 1984 ). (biomedcentral.com)
  • These cell lineages occur within microbial communities, and multicellular organisms in the form of tumours and cancer. (ox.ac.uk)
  • Finally, we consider features of multicellular organisms-a germ line and delayed reproductive maturity-and show that pleiotropy is again predicted to be important for maintaining cooperation. (ox.ac.uk)
  • The study of cancer in multicellular organisms provides the best evidence for pleiotropic constraints, where abberant cell proliferation is linked to apoptosis, senescence, and terminal differentiation. (ox.ac.uk)
  • Apoptosis (/̩æ.pəpˈtō.səs/ [1] ) is a form of programmed cell death in multicellular organisms. (wikidoc.org)
  • Newer cell fate determination techniques include lineage tracing performed using inducible Cre-lox transgenic mice, where specific cell populations can be experimentally mapped using reporters like brainbow, a colorful reporter that is useful in the brain and other tissues to follow the differentiation path of a cell. (wikipedia.org)
  • It also takes place in adult organisms during the renewal of tissues and the regeneration of missing parts. (worldwidefaqs.com)
  • In the model organism NC cells generate an amazing array of tissues, including peripheral and enteric nervous systems, cranial bones and cartilage, some cardiac muscle and virtually all pigmented cells in the body. (ca.gov)
  • APA naturally occurs during development and cellular differentiation, with around 70% of human genes displaying APA in particular tissues and cell types. (stanford.edu)
  • Although widespread, the role of APA in the biology of cells, tissues, and organisms has been controversial. (stanford.edu)
  • Her specific aim is to shed light onto the contribution of the cell division patterns and the differentiation path of a cell to the formation of the spiralian cell types and tissues. (uni-goettingen.de)
  • The stem cells suits human needs, does not cause harm and can be obtained from both adult and fetal does not conflict with religious beliefs, it has tissues, umbilical cord and early embryos. (who.int)
  • These processes include cell proliferation, differentiation, cellular movement and programmed cell death. (wikipedia.org)
  • During embryogenesis, for a number of cell cleavages (the specific number depends on the type of organism) all the cells of an embryo will be morphologically and developmentally equivalent. (wikipedia.org)
  • Determination is followed by differentiation, the actual changes in biochemistry, structure, and function that result in specific cell types. (wikipedia.org)
  • This threshold has been exceeded tens of times, perhaps because much of the requisite molecular machinery to facilitate cell-cell coordination is a shared primitive feature of living organisms, but also because some definitions of multicellularity encompass everything from simple bacterial colonies to badgers. (creation.com)
  • Furthermore, we use single-cell profiling to show that Tal1 -/- chimeric embryos display defects in early mesoderm diversification, and we thus demonstrate how combining temporal and transcriptional information can illuminate gene function. (nih.gov)
  • Together, this comprehensive delineation of mammalian cell differentiation trajectories in vivo represents a baseline for understanding the effects of gene mutations during development, as well as a roadmap for the optimization of in vitro differentiation protocols for regenerative medicine. (nih.gov)
  • Early vascular plants only developed by primary growth , in which the plants grew through cell division of the plant body. (newworldencyclopedia.org)
  • Secondary growth developed early (the Devonian period, 380 million years ago) in the evolution of vascular plants, which allowed for cell division to take place in the active regions of the plant's periphery. (newworldencyclopedia.org)
  • In the model organism Dictyostelium discoideum , loss of the CLN5 homolog, cln5 , impacts various cellular and developmental processes including cell proliferation, cytokinesis, aggregation, cell adhesion, and terminal differentiation. (frontiersin.org)
  • During growth, genes associated with protein ubiquitination/deubiquitination, cell cycle progression, and proteasomal degradation were affected, while genes linked to protein and carbohydrate catabolism were affected during early development. (frontiersin.org)
  • Morphogens are secreted signaling molecules that regulate tissue patterning and cell identity during early embryonic development. (frontiersin.org)
  • Remarkably, growing evidence over the last years arising from different invertebrate and vertebrate model organisms has shown that, after cell fate has been established, morphogens also control the precise wiring of the nervous system. (frontiersin.org)
  • One of the crucial questions is cell fate determination and differentiation, tissue formation, and what, what cell phenotype type each cell will become. (catsboard.com)
  • Cell determination starts early and progressively narrows the options as the cell steps through a programmed series of intermediate states-guided at each step by its genome, its history, and its interactions with neighbors. (catsboard.com)
  • The process reaches its limit when a cell undergoes terminal differentiation to form one of the highly specialized cell types of the adult body. (catsboard.com)
  • Many histone modifiers and chromatin remodelers have been implicated in stem cell pluripotency, cellular differentiation and development. (catsboard.com)
  • Biologists have long sought to understand how a fertilized egg can form an organism composed of hundreds of specialized cell types, each expressing a defined set of genes. (nature.com)
  • Starting from the zygotic genome, stage- and cell-type-specific transcription factors initiate regulatory cascades that induce cell differentiation. (nature.com)
  • Altered epigenomes can lead to changes in programmed cell differentiation or, when accidental, to disease (bottom right). (nature.com)
  • Develop a biological knowledge base common to contemporary biologists, encompassing microscopy, cell structure, cellular membranes, and nucleic acids biology. (uaeu.ac.ae)
  • Cell differentiation is caused by changes in gene expression. (worldwidefaqs.com)
  • What is cell differentiation in mitosis? (worldwidefaqs.com)
  • Cell differentiation is the process by which cells specialize to achieve their required functions. (worldwidefaqs.com)
  • Where does cell differentiation occur? (worldwidefaqs.com)
  • What is cell differentiation when does it occur? (worldwidefaqs.com)
  • What stage does cell differentiation occur? (worldwidefaqs.com)
  • What is differentiation in cell division? (worldwidefaqs.com)
  • Cell differentiation is the process by which dividing cells change their functional or phenotypical type. (worldwidefaqs.com)
  • Does cell differentiation happen by mitosis? (worldwidefaqs.com)
  • Cellular lysosomal degradative activity is key for healthy cell maintenance. (frontlinegenomics.com)
  • However, the in vitro differentiation conditions for all potential human NC cell fates are unknown. (ca.gov)
  • Lipids are vital building blocks of living organisms, essential to cell structure and signaling, and energy metabolism. (sanbio.nl)
  • 2 Lipids are major participants in the conversion of energy within cells, the transportation of substances, and cell growth, differentiation and apoptosis. (sanbio.nl)
  • Essentially, this means all the processes that make one cell of an organism different from another, that keep it that way and that allow that state to be passed on to that cell's descendants. (wiringthebrain.com)
  • These two usages thus relate to very different levels - one refers to the profile of gene expression of individual cell types and the other to the emergence of the phenotype of the organism. (wiringthebrain.com)
  • The progression of hepatocellular carcinogenesis is thought to involve the deregulation of genes that are critical to cellular processes, such as cell cycle control, cell growth, apoptosis, cell migration and spreading. (spandidos-publications.com)
  • To become familiar with the basic processes of embryology, cell differentiation and pattern formation and, in so doing, gain an appreciation of the developmental process as dialectic between cells, their genes and their environments. (brynmawr.edu)
  • However, recent advances in molecular biology, genetics, and stem cell biology have provided scientists a new window onto the impact of toxic substances on the cellular and molecular level. (eponline.com)
  • Development is a cumulative process and the effects of even small changes in progenitor cell division and differentiation over multiple generations could have a substantial effect on an organism. (eponline.com)
  • To address this issue, the program supports studies of mechanisms underlying cell differentiation and the establishment and maturation of functional circuitry in the developing brain, including disruptions of these mechanisms by risk factors associated with mental illness. (nih.gov)
  • 3 Unidirectional Flow of Genetic Information: The Central Dogma The primary structure is the sequence of bases that forms the genetic code that in turn stores all the information required for cellular metabolism, cell differentiation, cell division, and ultimately generation of a new organism. (dpforex.com)
  • Recent advances in live imaging and genetics of mammalian division, movement and cell differentiation leading to development which integrate observations of biochemical tissue formation [14 ]. (lu.se)
  • Mette Handberg-Thorsager: How does a complex organism develop from a single cell? (uni-goettingen.de)
  • Alongside development from a single cell, we propose that the evolution of pleiotropic constraints has been critical for cooperation in many cellular groups. (ox.ac.uk)
  • In recent years, interest in the possible molecular regulators of cell proliferation and differentiation in a wide range of regeneration models has grown significantly, but the cell kinetics of this process remain largely a mystery. (mdpi.com)
  • The C2C12 cell line, a mouse myoblast line, was used here to study the regulatory factors in myogenic differentiation. (cellimagelibrary.org)
  • In our research, we use the zebrafish embryo to investigate how intercellular Wnt protein transport is regulated and how signals are subsequently delivered to the target cell in a living vertebrate organism. (exeter.ac.uk)
  • There is also evidence that calcitriol modulates the action of cytokines and may regulate immune and inflammatory response, cell turnover, cell differentiation 4 . (drugbank.com)
  • Whereas infection by dengue virus and African zika virus was associated with increased production of proteins linked to cell domination and replication, the Brazilian strain modulated this highly important part of neural development, influencing the differentiation of neurons and glial cells [ astrocytes, microglia and oligodendrocytes ]," he said. (fapesp.br)
  • In contrast to necrosis , which is a form of traumatic cell death that results from acute cellular injury, apoptosis, in general, confers advantages during an organism's life cycle. (wikidoc.org)
  • That cell death is a completely normal process in living organisms was already discovered by scientists more than 100 years ago. (wikidoc.org)
  • They can be distinguished by antigen-specific surface receptors and other cell surface molecules called clusters of differentiation (CDs), whose presence or absence define some subsets. (msdmanuals.com)
  • These may be different molecules within the cells like proteins, polysaccharides, or nucleoproteins and may also be the whole cell, like a tumor cell or organisms like bacteria, viruses, fungi, parasites, or agents containing genetic material such as nucleic acids or lipids. (medscape.com)
  • The earliest cell in B-lymphocyte lineage that produces Ig is the pre-B lymphocyte. (medscape.com)
  • First, we utilized single cell sequencing to dissect the differentiation of stem cells to midbrain dopaminergic neurons. (lu.se)
  • Processes of disposal of cellular debris whose results do not damage the organism differentiate apoptosis from necrosis . (wikidoc.org)
  • Research on apoptosis has increased substantially since the early 1990s. (wikidoc.org)
  • Within an embryo, several processes play out at the cellular and tissue level to create an organism. (wikipedia.org)
  • Previous research showed that CLN5 participates in a variety of cellular processes. (frontiersin.org)
  • Originally coined by Conrad Waddington in his famous " epigenetic landscape ", the word signified the emergence of the eventual phenotype of an organism through the processes of development, starting from a particular genetic profile. (wiringthebrain.com)
  • Moreover, the surrounding sediment is rich in organic carbon, and contains evidence of eukaryotic organisms as well. (creation.com)
  • Alternative processing of nascent mRNAs is widespread in eukaryotic organisms and greatly impacts the output of gene expression. (stanford.edu)
  • To pursue Aim1 we will use in situ hybridization, immunostaining, prospective isolation of candidate NC cells by FACS and in vitro differentiation analysis to determine the vitro fates of candidate human NC cells. (ca.gov)
  • After losing interest in molecular biology she decided to apply her knowledge of genetics to cellular biology, more specifically pattern formation and regeneration in the hydra, a genus of freshwater polyps. (wepapers.com)
  • We construct a molecular map of cellular differentiation from pluripotency towards all major embryonic lineages, and explore the complex events involved in the convergence of visceral and primitive streak-derived endoderm. (nih.gov)
  • Diverse model systems are welcome as well as different cellular, biochemical and molecular approaches. (frontiersin.org)
  • Human NC cells have never been isolated and characterized on cellular and molecular levels. (ca.gov)
  • To prove (or disprove) this hypothesis we will rigorously examine the molecular and cellular fates of candidate NC cells from hES-NPCs cultures both in vitro and in vivo. (ca.gov)
  • It is obviously true that molecular mechanisms of gene regulation effect (as in mediate) the development of an organism. (wiringthebrain.com)
  • This course investigates cellular and molecular mechanisms that regulate development. (brynmawr.edu)
  • This program encompasses studies (a) of prenatal, early postnatal and juvenile development, (b) at the molecular, cellular and systems levels, (c) involving in vitro preparations or in vivo analysis in model organisms. (nih.gov)
  • Mette Handberg-Thorsager studies the embryo of the ragworm Platynereis dumerilii to understand the interplay between molecular and cellular-physical mechanisms acting during spiralian development. (uni-goettingen.de)
  • Molecular Components of the Immune System The immune system consists of cellular components and molecular components that work together to destroy antigens (Ags). (msdmanuals.com)
  • At these sites, which are a compound of stromal cells, extracellular matrix and soluble factors, complex molecular interactions that maintain the essential properties of stem cells occur, such as self-renewal and differentiation into multiple lineages, according to the organism's needs. (bvsalud.org)
  • The evolution of cooperation in cellular groups is threatened by lineages of cheaters that proliferate at the expense of the group. (ox.ac.uk)
  • In contrast to an earlier study, here we show how the evolution of pleiotropic genetic architectures-which link the expression of cooperative and private traits-can protect against cheater lineages and allow cooperation to evolve. (ox.ac.uk)
  • Evolutionary conservation is one of the reasons that model systems such as the fly (Drosophila melanogaster), the mouse (Mus musculus), and other organisms are used as models to study embryogenesis and developmental biology. (wikipedia.org)
  • Throughout this paper I will detail the early career of Dr. Nusslein-Volhard and the ways in which her research helped to revolutionize the field of developmental biology as it pertains to embryonic development and gene analysis/function. (wepapers.com)
  • Across the animal kingdom, gastrulation represents a key developmental event during which embryonic pluripotent cells diversify into lineage-specific precursors that will generate the adult organism. (nih.gov)
  • Laboratory sessions focus on observation and experimental manipulation of early vertebrate and invertebrate embryos, as well as reading and discussing research papers in developmental biology. (brynmawr.edu)
  • It has been almost an established dogma that DNA methylation patterns form during embryogenesis by innate organized developmental programs and that DNA methylation is mainly involved in cellular differentiation. (biomedcentral.com)
  • If this disruption occurs during critical developmental periods, like fetal growth or early childhood, it can have a significant impact. (eponline.com)
  • Studies in single model organisms of developmental stages or mechanisms that are known to be highly specific to that monophyletic group and unlikely to yield generalized biological principles or be relevant to human brain development, health or disease. (nih.gov)
  • While most of the CLN genes have been studied, the precise cellular mechanisms impacted by CLN gene mutations remain elusive. (frontiersin.org)
  • Cellular identity is now accepted to be the result of the expression of specific combinations of genes (Fig. 1 ). (nature.com)
  • And there are indeed a number of examples where the behavioural phenotype of an organism has been linked to the epigenetic state of particular genes in cells in particular brain regions. (wiringthebrain.com)
  • Interestingly, while genes which commonly code for cellusomes, protein complexes which breakdown crystalline cellulose, are present the organism is unable to grow solely on cellulose substrates (7). (thecoffeeparlor.com)
  • His efforts are focused on the identification of the complete set of biomineralizing effector genes in the pulmonate gastropod Lymnaea stagnalis , and on identifying the gene regulatory and cellular communication events that coordinate the initiation of shell formation in the early snail embryo. (uni-goettingen.de)
  • It was therefore believed that DNA methylation patterns once formed remained fixed since cellular differentiation was believed to be terminal. (biomedcentral.com)
  • We followed up this analysis by showing that loss of cln5 alters the intracellular and extracellular amounts of proliferation repressors during growth and increases the extracellular amount of conditioned medium factor, which regulates cAMP signalling during the early stages of development. (frontiersin.org)
  • Lipids have vital functions in extra- and intracellular signal transduction and in the magnification of cellular regulatory cascades. (sanbio.nl)
  • Activated macrophages kill intracellular organisms and secrete cytokines (eg, tumor necrosis factor-alpha [TNF-alpha], IL-10). (msdmanuals.com)
  • Almost all animals undergo a similar sequence of events during very early development, a conserved process known as embryogenesis. (wikipedia.org)
  • Altogether, they will contribute in different and complementary ways to build a holistic view of the roles that early development morphogens play during the assembly, maintenance and/or regeneration of functional synapses. (frontiersin.org)
  • During germline reprogramming and early embryogenesis in mice, methylation marks are removed to allow for development to commence, but the methylation mark is converted into hydroxymethyl-cytosine so that it is recognized and methylated once that area of the genome is no longer being used, [5] which serves as a memory for that TEI mark. (cloudfront.net)
  • Embryonic differentiation is the process of development during which embryonic cells specialize and diverse tissue structures arise. (worldwidefaqs.com)
  • Differentiation from visibly undifferentiated precursor cells occurs during embryonic development, during metamorphosis of larval forms, and following the separation of parts in asexual reproduction. (worldwidefaqs.com)
  • In Aim2 we will determine the in vivo fates of candidate human NC cells by transplanting genetically labeled hES-NPCs and their subpopulations into the early chick embryo and following their fates during chick development. (ca.gov)
  • It was derived from Aristotle's term " epigenesis ", which means pretty much the same thing - that organisms emerge through a program of development, as opposed to the theory of preformationism (where a teeny organism is already formed inside an egg and simply grows). (wiringthebrain.com)
  • That is what cellular differentiation and coordinated organismal development entail. (wiringthebrain.com)
  • Regulation and function of alternative polyadenylation in development and differentiation. (stanford.edu)
  • In this review, we summarize current understanding of how APA is regulated during development and cellular differentiation and how the resulting change in 3'UTR content affects multiple aspects of gene expression. (stanford.edu)
  • They can be found very early in Earth's fossil records (about 3.25 billion years ago) as both Archaea and Bacteria, and commonly protect prokaryotic cells by providing them with homeostasis, encouraging the development of complex interactions between the cells in the biofilm. (wikipedia.org)
  • Tissue development is a key process for life starting from the earliest embryonic stages during which cells differentiate into later organs composing an entire body. (exeter.ac.uk)
  • We propose that modulation of DNA methylation in response to environmental cues early in life serves as a mechanism of life-long genome adaptation. (biomedcentral.com)
  • Recent data suggest however that DNA methylation is more attentive to information from the environment including the social environment particularly early in life (Szyf et al. (biomedcentral.com)
  • 2007 ). It is proposed here that the DNA methylation pattern bears not just the tissue-specific identity but also the individual identity formed as a response to interactions with the environment early in life and throughout life. (biomedcentral.com)
  • Readers will be exposed to knowledge about life at the sub-cellular level, microbial genetics, and the design and deployment of synthetic DNA to create real-world projects. (leanpub.com)
  • Here we try to elucidate the cellular aspects of regeneration by EdU incorporation in intact and posteriorly amputated annelid Alitta virens using quantitative analysis. (mdpi.com)
  • It displays no activity of catalase, an enzyme important for aerobic organisms in order to convert a toxic byproduct of oxygen metabolism, hydrogen peroxide, to water and oxygen (5). (thecoffeeparlor.com)
  • Sometimes, this necessarily has to step out of the "recipe book" frame and become more technical or didactic, for example when considering the practicalities of DNA design and cellular metabolism. (leanpub.com)
  • Again, Brazilian zika modulated the cellular metabolism and also controlled the metabolism of the RNA [ expressed in the nuclei of infected cells ]. (fapesp.br)
  • Importantly, such mechanisms may provide one means whereby environmental factors or particular experiences can have long-lasting effects on an organism, by changing patterns of gene expression in particular cells in a stable manner. (wiringthebrain.com)
  • EGF stimulates tissue growth by initiating a variety of cellular mechanisms. (asu.edu)
  • The evolution of this vascular tissue allowed for an early dominance of these plants on land (first appearing 430 million years ago, during the Silurian period), giving them the ability to transport water and dissolved minerals through specialized strands of elongated cells that run from the plant root to the tips of the leaves . (newworldencyclopedia.org)
  • Continued progression of cellular degradation results in collective stripping of the myelin sheaths of the cells, loss of neuronal conductance, and, subsequently, numbness. (ceufast.com)
  • What Causes Differentiations Of Cells In Complex Organisms? (worldwidefaqs.com)
  • The PI laboratory has recently developed an efficient procedure for the rapid differentiation of human ES cells into uniform neural precursors (hES-NPCs), which was hitherto unachievable. (ca.gov)
  • One of the obstacles in the analysis of new chemicals is the difficulty in developing a system that is sensitive enough and can make predictions that are true for both individual cells and the entire organism," Noble said. (eponline.com)
  • The microbial cells growing in a biofilm are physiologically distinct from planktonic cells of the same organism, which, by contrast, are single cells that may float or swim in a liquid medium. (wikipedia.org)
  • Microbes form a biofilm in response to a number of different factors, [9] which may include cellular recognition of specific or non-specific attachment sites on a surface, nutritional cues, or in some cases, by exposure of planktonic cells to sub-inhibitory concentrations of antibiotics . (wikipedia.org)
  • mitotically active cells of intact segments do not significantly contribute to the blastemal cellular sources. (mdpi.com)
  • After cultured in differentiation medium for 3 days, these cells differentiated i. (cellimagelibrary.org)
  • Normally, viruses infect cells in order to multiply freely and then advance to other parts of the host organism. (fapesp.br)
  • The cellular response is mainly a lymphocyte-mediated reaction, whereas the humoral response includes production of antibodies against the antigen by the plasma cells. (medscape.com)
  • Unicellular for those cells that are derived from human organisms are primed to replicate (clone) pre-embryos, which seem to have a high themselves by nature. (who.int)
  • Studying model organisms provides information relevant to other animals, including humans. (wikipedia.org)
  • Volvox , the Fierce Roller, is a model organism for the evolution of multicellularity and cellular differentiation. (freethoughtblogs.com)
  • To these ends his team is also developing methods to characterize gene function in this nontraditional model organism. (uni-goettingen.de)
  • The lab uses marine model systems including the starfish, Patiria miniata and the jellyfish, Clytia hemisphaerica that are exceptionally suited for high-resolution livecell microscopy assays, which are frequently combined in his lab with quantitative image analysis and biophysical modeling to reveal conserved principles of cellular organization. (uni-goettingen.de)
  • We develop an age-structured model of cellular groups and show that cooperation breaks down more slowly within groups that tie expression to a private trait than in groups that do not. (ox.ac.uk)
  • Naturally occurring Bruton's tyrosine kinase mutations have no dominant negative effect in an X-linked agammaglobulinaemia cellular model. (lu.se)
  • The course is intended to complement Basic Biology I (which covers cellular and biochemical basis of life) by covering the basic concepts relating to whole-organism topics. (uaeu.ac.ae)
  • This appendix presents a brief overview of the areas of radiation physics, chemistry, and biology and is based to a large extent on the reviews of Mettler and Moseley (1985), Hobbs and McClellan (1986), Eichholz (1982), Hendee (1973), and Early et al. (cdc.gov)
  • BPA's in plastic are associated with early puberty in females, lowered sperm counts, altered functions of reproductive organs, obesity, altered sex-specific behaviors, and increased rates of some breast, ovarian, testicular, and prostate cancers. (hyperboreanhealth.com)
  • RACK1 was expressed transiently in the skeletal muscle of post-natal mice, being abundant in the early phase of muscle growth and almost disappearing in adult mature fibers. (sdbonline.org)
  • The dynamics of RACK1 levels in isolated adult SC of mice, i.e., progressively high during differentiation and low compared to proliferating conditions, and RACK1 silencing indicated that RACK1 promotes both the formation of myotubes and the accretion of nascent myotubes. (sdbonline.org)
  • Cellular differentiation occurs in the human fetal pituitary between the eighth and sixteenth weeks of gestation. (worldwidefaqs.com)
  • The body's immune system can react adaptively against the antigen via 2 pathways: cellular or humoral. (medscape.com)
  • Due to its fast time-to-result (TTR), excellent strain differentiation performance, low cost per sample, ease of use, robustness and throughput, the IR Biotyper can perfectly complement next-generation sequencing (NGS) strain typing, which typically requires more time, training and infrastructure in core labs. (bruker.com)
  • It includes cellular functioning and organization and the transformation of energy. (uaeu.ac.ae)
  • Use a biological knowledge base common to contemporary biologists in cellular, sub-organismic, organismic, and systems levels of biological organization. (uaeu.ac.ae)
  • Although the fossils are macroscopic, they do not seem to represent anything other than the basic type of multicellularity, which occurs earlier in time in the form of stromatolites. (creation.com)
  • One reason is that there may be no clear boundaries between stages throughout the entire lifetime of the organism. (elifesciences.org)
  • SGC can be treated at early stages by surgery, although patients with advanced stages of SGC present poor prognosis [ 6 , 7 ]. (genominfo.org)
  • Epitopes are a component of the antigen that are recognized by the immune system and determine whether the cellular or the humoral arm of the immune system shall be activated against that particular antigen. (medscape.com)
  • Lipid research encompasses the large-scale profiling of cellular lipids, the quantification of specific lipids in biological samples and the documentation of the interactions between lipids and other lipids, proteins and metabolites within the body. (sanbio.nl)