• Organ transplantation is often the last resort for treating end-stage illnesses, but managing transplant wait-lists is challenging because of organ scarcity and the complexity of assessing donor-recipient compatibility. (mlr.press)
  • As a result, the list of indications for solid-organ transplantation has expanded considerably, placing increasing pressure on an already limited supply of donor organs. (medscape.com)
  • This article discusses the pathophysiology and techniques of organ preservation and describes various preservation solutions currently used for kidney , liver , pancreas , small-bowel , lung , and heart transplantation . (medscape.com)
  • The first successful organ transplantation was performed by John Merrill and Joseph Murray at the Peter Bent Brigham Hospital, between two identical twins, in 1954. (medscape.com)
  • The removal, storage, and transplantation of a solid organ from a donor profoundly alters the homeostasis of the interior milieu of the organ. (medscape.com)
  • These effects manifest in the degree to which the return of normal organ function is delayed or prevented after transplantation is completed. (medscape.com)
  • The injury an organ sustains during recovery, preservation, and transplantation occurs primarily as a result of ischemia and hypothermia. (medscape.com)
  • Damage to organs during transplantation occurs in 2 phases: the warm ischemic phase and the cold ischemic phase. (medscape.com)
  • In the Finnish study of long-term survival, Rebekka Salonen, with Tampere University in Finland, and colleagues studied outcomes for 233 patients who had undergone transplantation at one center between 1982 and 2015. (medscape.com)
  • As living donors become an increasingly important source of organs for kidney and liver transplantation, the world transplant community strives to ensure that these life-saving procedures maximize the benefits to recipients while minimizing the risks to donors. (sciencedaily.com)
  • This very special issue of Transplantation is dedicated to the approximately 33,000 living kidney and 5,000 living liver donors who provided organs for transplantation in 2014 across the world," comments Prof. Jeremy R. Chapman, Editor-in-Chief of Transplantation . (sciencedaily.com)
  • Dr. Chapman adds, "This issue will provide food for thought for everyone involved in living-donor organ transplantation: donor, recipient, physician, surgeon, transplant nurse, patient association, transplant coordinator, public policy analyst, lawmaker and the most important families who share the burden of decision-making. (sciencedaily.com)
  • The increased need for organ transplantation is in part being driven by the rising rate of Canadians living with end-stage kidney disease, which went up 32% over the 10 years studied. (newswire.ca)
  • This has led to an increase of almost 430% in the number of DCD organs used for transplantation, from 42 in 2009 to 222 in 2018. (newswire.ca)
  • DCD transplants of other organs like hearts is a bit more variable due to the complex nature of determining organ suitability for transplantation. (newswire.ca)
  • As more experience in this area grows, we hope to see gains in DCD transplants in all organ groups as well as improved access to transplantation. (newswire.ca)
  • An increase in deceased donor rates is promising because 1 deceased donor can provide up to 8 organs for transplantation. (newswire.ca)
  • For deceased donors, the average number of organs used for transplantation was 3 for all donors and 4 for donors age 39 and younger. (newswire.ca)
  • Ottawa, ON - Canadian transplant patients have new hope as the Harper Government today announced the launch of a new national transplantation research program that will develop new knowledge and health care practices that address barriers to tissue and organ donation and will improve health outcomes for transplant recipients in Canada. (ohri.ca)
  • The program will transform the field of transplantation by addressing the barriers to donation therefore increasing the number of available organs, improving the quality and viability of donated organs and grafts, and enhancing long-term survival and quality of life of transplant patients. (ohri.ca)
  • Transplantation is the most effective treatment for end-stage organ failure, but organ survival is limited by immune rejection and the side effects of immunosuppressive regimens. (lu.se)
  • Our surgeons at the Center for Transplantation have extensive experience in heart, kidney, liver, lung and multi-organ transplants from deceased donors and kidney and liver transplants from living donors. (ucsd.edu)
  • Erasmus ME, van der Bij W. Death after lung transplantation: improving long term survival despite perilous early postoperative years. (smw.ch)
  • Survival in adult lung transplantation: where are we in 2020? (smw.ch)
  • Inducing graft acceptance without chronic immunosuppression remains an elusive goal in organ transplantation. (uni-muenchen.de)
  • In May 2010, the Sixty-third World Health Assembly adopted resolution WHA63.22,1 in which it endorsed the updated WHO Guiding Principles on Human Cell, Tissue and Organ Transplantation and provided strategic directions to support progress in human organ, tissue and cell donation with the aim of maximizing the benefits of transplantation, meeting the needs of recipients, protecting donors and ensuring the dignity of all involved. (who.int)
  • The transplantation of human tissues, organs or cells is an established form of treatment that has been acknowledged as the best and very often only life-saving therapy for several serious and life-threatening congenital, inherited and acquired diseases and injuries. (who.int)
  • The benefits of human tissue transplantation can be seen in both children and adults, including in survival rates following severe burn trauma, recovery of movement, closure of chronic wounds, rehabilitation of heart function and restoration of sight. (who.int)
  • Organ transplantation is often the best, if not the only, treatment for acute and chronic organ failure. (who.int)
  • Kidney transplantation is a far more favourable treatment modality versus dialysis in terms of survival, quality of life and cost-effectiveness. (who.int)
  • In June 2018, the Secretariat established the WHO Task Force on Donation and Transplantation of Human Organs and Tissues as an advisory group composed of experts from all WHO regions. (who.int)
  • End-stage kidney disease (ESKD) is the last stage of a chronic kidney disease, which if not addressed leads to premature death and, although it can be addressed by dialysis, kidney transplantation is the preferred treatment due to better survival rates, improved quality of life and cost efficiency. (europa.eu)
  • However, although immunosuppressive therapies have represented a huge step forward in organ transplantation, their use still entails important problems. (europa.eu)
  • Post-transplantation maintenance therapy with low-dose lenalidomide yields improved PFS and overall survival (OS). (medscape.com)
  • For most organs, patient survival is greater than 80% after 5 years. (newswire.ca)
  • We have performed thousands of successful transplant procedures since 1968, with patient survival rates exceeding the national average . (ucsd.edu)
  • Our patient survival rates exceed the national average for all programs, placing us among the nation's best transplant centers by the Scientific Registry of Transplant Recipients (SRTR). (ucsd.edu)
  • Sharing information helps us understand the condition better, improve treatments and increase patient survival. (seattlechildrens.org)
  • Trends in cancer incidence, mortality, and patient survival in the United States, as well as many other studies, are derived from this data bank. (cdc.gov)
  • Providing continuing information on changes over time in the extent of disease at diagnosis, trends in therapy, and associated changes in patient survival. (cdc.gov)
  • and c) determinants of the length and quality of patient survival. (cdc.gov)
  • Participants Over 5500 solid organ transplant recipients have been enrolled in all six Swiss transplant centres by end of 2019, around three-quarter of them for kidney and liver transplants. (bmj.com)
  • Conclusions And Relevance: Our analysis demonstrated that more than 2 million life-years were saved to date by solid-organ transplants during a 25-year study period. (houstonmethodist.org)
  • Transplants should be supported and organ donation encouraged. (houstonmethodist.org)
  • A lot of progress has been made with regards to losing solid organ transplants early from rejection," Filler said. (medscape.com)
  • At the end of 2018, there were 4,351 people on wait lists for organ transplants (2,890 active and 1,461 on hold i ). (newswire.ca)
  • We know that organ transplants save lives. (newswire.ca)
  • Our Government recognized the need for a national program to help Canadians who have received or who are waiting for tissue and organ transplants," said Minister Aglukkaq. (ohri.ca)
  • This program will provide important information to guide the development of policies and programs that increase tissue and organ donation in Canada and enhance the survival and quality of life of Canadians who receive transplants. (ohri.ca)
  • The Canadian National Transplant Research Program is a new national initiative designed to increase organ and tissue donation in Canada and enhance the survival and quality of life of Canadians who receive transplants. (ohri.ca)
  • We hope to reduce the need for multiple organ transplants. (seattlechildrens.org)
  • We engineered CAR-T cells to express interleukin (IL)-7 and CCL19 (7 × 19 CAR-T cells), as these factors are essential for the maintenance of T-cell zones in lymphoid organs. (nature.com)
  • Should the remark on the NHI Card be different from the expressive organ donation willingness during the clinical treatment process, the later shall prevail. (gov.tw)
  • The Administration, the household offices and the motor vehicle supervision offices shall work together and enquire the adults coming forward for applying for or replacing identity card, driver license or NHI Card about their willingness of organ donation. (gov.tw)
  • Living-organ donation confronts patients, healthcare professionals, and society with a challenging set of concerns unlike any other type of procedure. (sciencedaily.com)
  • Another paper provides a thoughtful update on Iran's controversial paid living organ donation program. (sciencedaily.com)
  • April is National Donate Life Month , a time to raise awareness about donation, encourage Americans to register as organ, eye and tissue donors, and honor those that have saved lives through the gift of donation. (wusa9.com)
  • Improved organ donation practices across Canada have resulted in a 33% increase in transplant procedures over the last decade. (newswire.ca)
  • Due to organ shortages, many countries have expanded deceased organ donation practice beyond brain death cases to include donation after cardiac death (DCD) - meaning the heart has permanently stopped beating. (newswire.ca)
  • The release of CIHI's organ donation data is an important reminder for all Canadians who wish to become donors to register to be an organ donor and to speak to your family about your wishes. (newswire.ca)
  • The CNTRP is the first program in the world to unite and integrate the solid organ transplant, bone marrow transplant and the donation and critical care research communities together in a groundbreaking national research endeavour. (ohri.ca)
  • Canadian transplant centres and organizations are working together, for patients like me," said Hélène Campbell, double-lung transplant recipient and organ donation advocate. (ohri.ca)
  • Organ donation is voluntary, and mechanisms are in place to protect your health, safety and privacy. (ucsd.edu)
  • Techniques for organ preservation serve to minimize this damage to promote optimal graft survival and function. (medscape.com)
  • For the 10% of patients showing an operational tolerance, immunosuppressive drugs could be gradually reduced or withdrawn without compromising graft survival. (europa.eu)
  • T cells are central to the process of transplant rejection through allorecognition of foreign antigens leading to their activation, and the orchestration of an effector response that results in organ damage. (lu.se)
  • Post-surgery recovery services help build strength and reduce the likelihood of organ rejection. (ucsd.edu)
  • Thus, the mycophenolate mofetil dose or mycophenolic acid plasma concentration are not a primary factor related to organ rejection, but chronic lung allograft dysfunction may be influenced by other components of immunosuppression or other factors. (smw.ch)
  • Transplant rejection is detected by analyzing a biopsy of the transplanted organ. (nih.gov)
  • Could early detection and treatment of rejection save the transplanted organ from rejection? (nih.gov)
  • The focus of APO is to investigate whether early detection and treatment of rejection improves transplant survival. (nih.gov)
  • APO is also planning a clinical trial to assess whether early detection and treatment of rejection improves survival in lung transplant patients and also engaged in additional studies to understand molecular mechanisms of transplant rejection. (nih.gov)
  • Maintenance of immunosuppression after solid-organ transplant is essential in order to prevent short-and long-term complications such as acute cellular rejection and chronic lung allograft dysfunction. (nih.gov)
  • B) Chronic rejection (~50% patients): long-term loss of function in transplanted organs, even under immunosuppressive therapy. (europa.eu)
  • The growth in the number of patients wanting or waiting for a transplant has outpaced the supply of available organs. (medscape.com)
  • The 20-year survival rates were 86.1% for kidney recipients, 58.5% for liver recipients, and 61.4% for heart recipients. (medscape.com)
  • Although Canada is seeing more DCD donors, there is considerable variation in the type of organs being transplanted: liver, heart and pancreas had fewer to no organs used from DCD donors compared with kidney and lung. (newswire.ca)
  • This information is published in CIHI's annual Canadian Organ Replacement Register report, which includes statistics on all donations for kidney, heart, lung, liver, pancreas and intestine transplantations. (newswire.ca)
  • Other individuals have a multitude of the most severe symptoms of end-stage liver disease and a limited chance for survival. (medscape.com)
  • Intestinal failure can lead to failure of other organs - especially other parts of the digestive system or the liver. (seattlechildrens.org)
  • After a median follow-up duration of 12 months, the estimated 3-year progression-free survival (PFS) and overall survival (OS) rates were 61.3 and 61.7% respectively. (bvsalud.org)
  • In a Phase III trial, The Radiation Therapy Oncology Group (RTOG) showed improved progression-free survival (PFS) for high-risk prostate cancer patients treated with Whole Pelvis Radiation Therapy (WPRT) compared with prostate-only radiation therapy (PORT) [4]. (scirp.org)
  • [ 1 ] Although the combination of carfilzomib (second-generation proteasome inhibitor) with lenalidomide and dexamethasone showed higher efficacy in phase II trials, particularly in high-risk patients, interim analysis in an ongoing phase III clinical trial showed that progression-free survival (PFS) was not superior to that with bortezomib/lenalidomide/dexamethasone. (medscape.com)
  • [ 8 ] Shortage of organs for transplantations prolongs patients' waiting time and increases the mortality and morbidity rates during the waiting time. (medscape.com)
  • Despite this progress, Canada still has a shortage of organs for transplant. (newswire.ca)
  • Apu Patel, 48, is living proof that organ donors save lives. (wusa9.com)
  • Of the 762 deceased organ donors, 60% were male. (newswire.ca)
  • Of the 555 living organ donors, 63% were female. (newswire.ca)
  • The organs can come from either living donors or deceased donors. (ucsd.edu)
  • INTRODUCTION: Development of chronic lung allograft dysfunction is a limiting factor for post-lung transplant survival. (smw.ch)
  • This synergistic nanoimmunotherapy resulted in indefinite allograft survival. (uni-muenchen.de)
  • The most important challenge is to achieve the long-term survival of the transplanted organ (also known as graft or allograft). (europa.eu)
  • Select organ toxicity potentially results from compound accumulation in a particular tissue, cell types within organs, metabolism, and off-target effects. (nih.gov)
  • The program is led by Drs. Lori West at the Alberta Transplant Institute at the University of Alberta in Edmonton and Marie-Josée Hébert at the Université de Montréal and brings together 105 investigators and 86 collaborators from across Canada to carry out research and develop resources to help Canadians waiting for a tissue or organ transplant. (ohri.ca)
  • Gamma knife surgery as monotherapy with clinically relevant doses prolongs survival in a Human GBM Xenograft Model. (uib.no)
  • Two months after keratoplasty there was no statistically significant difference in central endothelial cell loss between the organ-cultured grafts and those preserved in McCarey-Kaufman medium (9% vs 7% cell loss, respectively). (nih.gov)
  • On the first postoperative day, the organ-cultured grafts were thicker than those grafts preserved in McCarey-Kaufman medium, and the thickest corneas were those cultured for the longest times. (nih.gov)
  • Kaplan-Meier survival functions were used for time-to-event analysis. (houstonmethodist.org)
  • Kaplan-Meier survival curves showed that T/A PTLD was associated with decreased all-cause mortality compared with PTLD at other sites (log-rank 0.004), even after adjustment for histological subtype (P = .047). (bepress.com)
  • Sodium-glucose cotransporter 2 (SGLT2) inhibitors should be studied in randomized controlled trials in pediatric solid organ recipients, Filler said. (medscape.com)
  • In this paper, we develop a data-driven model for (real-time) organ allocation using observational data for transplant outcomes. (mlr.press)
  • To reason about organ allocations, the model uses synthetic controls to infer a patient's survival outcomes under counterfactual allocations to the different organ types{-} the model is trained end-to-end to optimise the trade-off between patient waiting time and expected survival time. (mlr.press)
  • Several organ-preservation solutions are available, and these are being constantly modified to provide improved organ storage and outcomes. (medscape.com)
  • The goal of this research is to better inform pre- and post-transplant clinical management and further refine donor-recipient organ matching to improve long-term outcomes and survival in lung transplant patients. (nih.gov)
  • Furthermore, although cooling of the neonate results in improved neurological outcomes for a small proportion of treated infants, it does not provide any benefit to the other organ systems affected by asphyxia at birth. (frontiersin.org)
  • The organs referred to in this Act shall include tissues. (gov.tw)
  • Cells Tissues Organs (2001) 169 (4): 347-354. (karger.com)
  • Sara Kathryn Smith, MD, knows better than most that studying pediatric organ transplant recipients in adulthood can be a challenge. (medscape.com)
  • The study is the first to assess the survival rate for pediatric patients two decades after surgery, the researchers say. (medscape.com)
  • In a general pediatric intensive care unit (PICU) population, the PEdiatric Logistic Organ Dysfunction-2 score (PELOD-2) score had both a good discrimination and calibration, allowing to describe the clinical outcome of critically ill children throughout their stay. (springer.com)
  • AL amyloidosis is a rare plasma cell dyscrasia characterized by multi-organ involvement and poor prognosis . (bvsalud.org)
  • Although the majority of research is directed toward reducing the brain injury that results from intrapartum birth asphyxia, the multi-organ injury observed in surviving neonates is of equal importance. (frontiersin.org)
  • The aim of this review is to summarize the current knowledge of the multi-organ effects of intrapartum asphyxia, with particular reference to the findings from our laboratory using the precocial spiny mouse to model birth asphyxia. (frontiersin.org)
  • Furthermore, we reviewed the current treatments available for neonates who have undergone intrapartum asphyxia, and highlight the emergence of maternal dietary creatine supplementation as a preventative therapy, which has been shown to provide multi-organ protection from birth asphyxia-induced injury in our preclinical studies. (frontiersin.org)
  • For those infants that do survive, the multi-organ damage that can ensue means the risk of developing severe life-long morbidities is high. (frontiersin.org)
  • The unpredictable nature of the many obstetric complications that contribute to intrapartum asphyxia, in addition to the multi-organ damage associated with intrapartum oxygen deprivation ( 11 ), presents a unique set of challenges to clinical and research professionals in their endeavor to implement effective treatments for intrapartum asphyxia. (frontiersin.org)
  • In order to resume patient's organ function or to save lives, this Act is enacted to permit physicians to remove organs either from a corpse or a living person. (gov.tw)
  • For decades Harvey Organ has been a precious metals investor and student of the market. (libsyn.com)
  • A mean of 4.3 life-years were saved (observed to date) per solid-organ transplant recipient. (houstonmethodist.org)
  • A monoclonal antibody against tumor necrosis factor-alpha improves survival in experimental multiple organ dysfunction syndrome. (ru.nl)
  • When performing a transplant operation by removing an organ from a corpse, the organ donor shall be certified dead by his/her attending physician before the operation can be performed. (gov.tw)
  • However, if the non-disease cause of death is not related to the organ or organs to be removed as determined by the attending physician, the organ/organs may still be removed by the prosecutor's and the next of kin's written consent if completion of the postmortem examination may result in missing the best time for removing the organ/organs. (gov.tw)
  • We report the case of a patient with extreme hypernatremia associated with acute anuric renal failure and multiple organ failure treated with hypo and isotonic solutions. (scirp.org)
  • There are plenty of P-Organ abilities to slot into the P-Organ to earn synergies, and the perfect options may vary slightly based on your Lies of P class and build--but we feel these are the ones that will generally improve survivability and damage output for most players. (gamespot.com)
  • Some organ damage may be permanent. (medlineplus.gov)
  • Kidneys (1,706) and livers (533) were the top organs transplanted, followed by lungs (361), hearts (189) and pancreases (57). (newswire.ca)
  • [ 1 ] With such constraints, preservation of organs for transport between centers becomes crucial in order to facilitate broader sharing of these limited-resource items. (medscape.com)
  • His multimodal approach to organ protection is now used in many major aortic centers around the world. (bcm.edu)
  • The DVH analysis showed good coverage of PTVs and organs at risk doses were acceptable. (scirp.org)
  • Our model integrates a queuing-theoretic framework with unsupervised learning to cluster the organs into "organ types", and then construct priority queues (associated with each organ type) wherein incoming patients are assigned. (mlr.press)
  • Design, Setting, And Participants: In this retrospective analysis of UNOS data for solid-organ transplant during a 25-year period (September 1, 1987, through December 31, 2012), we reviewed the records of 1 112 835 patients: 533 329 recipients who underwent a transplant and 579 506 patients who were placed on the waiting list but did not undergo a transplant. (houstonmethodist.org)
  • To determine whether 2 readily available indicators predicted survival among patients with Ebola virus disease in Sierra Leone, we evaluated information for 216 of the 227 patients in Bo District during a 4-month period. (cdc.gov)
  • At least partial hematological response after first cycle of treatment predicts organ response and long-term survival for patients with AL amyloidosis receiving bortezomib-based treatment. (bvsalud.org)
  • We retrospectively evaluated the organ response (OR) and long-term survival of newly diagnosed AL amyloidosis patients who received first-line bortezomib -containing induction therapy , aiming to identify the clinical indication of a 50% reduction in the difference between involved and uninvolved free light chains (dFLC) after first cycle of treatment . (bvsalud.org)
  • These results demonstrated that early reduction of dFLC after the first cycle of treatment is predictive of achieving an OR and long-term survival in AL patients receiving bortezomib . (bvsalud.org)
  • Survival of patients with cancers of the female genital organs in Poland, 2000-2019. (bvsalud.org)
  • Research shows there may be plenty of room to improve patients' long-term survival. (medscape.com)
  • Using organ-on-a-chip technology, they want to try to prevent the inevitable for brain stem cancer patients. (utwente.nl)
  • BioHope is a leading biomedical company specialized in the development of novel diagnostic tools and advanced therapies for clinical management of organ transplanted patients. (europa.eu)
  • As such, the immune system is prepared to reject a "foreign organ", something that is nowadays prevented by prescribing immunosuppressive therapies (drugs that suppress/reduce the effectiveness of the immune system) to the patients for their whole life. (europa.eu)
  • Age-dependent association between protein expression of the embryonic stem cell marker Cripto-1 and survival of glioblastoma patients. (uib.no)
  • OTTAWA , Dec. 5, 2019 /CNW/ - In 2018, there were 2,782 organ transplant procedures performed in Canada , according to the latest information published by the Canadian Institute for Health Information (CIHI). (newswire.ca)
  • The Financial Survival Network is dedicated to helping you build your financial fortress so that you can survive and thrive in the new economy. (libsyn.com)
  • You need the Financial Survival Network now more than ever. (libsyn.com)
  • There is a very high prevalence of renal dysfunction in all solid organ transplant recipients. (medscape.com)
  • Organ dysfunction scores, based on physiological parameters, have been created to describe organ failure. (springer.com)
  • MODS scores can be used to assess the presence and severity of organ dysfunction on admission and throughout the stay [ 9 ]. (springer.com)
  • However, some authors have voiced their concern regarding using organ dysfunction scores in specific subpopulations [ 9 ]. (springer.com)
  • Infiltration, accumulation, and survival of chimeric antigen receptor T (CAR-T) cells in solid tumors is crucial for tumor clearance. (nature.com)
  • In mice, 7 × 19 CAR-T cells achieved complete regression of pre-established solid tumors and prolonged mouse survival, with superior anti-tumor activity compared to conventional CAR-T cells. (nature.com)
  • In a 2022 study , researchers examined the survival rate of people 40 to 74 years old and people over the age of 75 who were treated for bowel obstruction between 2009 and 2019. (healthline.com)
  • The purpose of this study was to estimate cancer survival in Poland between 2000 and 2019 for malignant neoplasms of female genital organs (FGO). (bvsalud.org)
  • The decreased demand probably accounts for the occasional survival after prolonged cardiac arrest due to extreme hypothermia. (msdmanuals.com)
  • Keep reading to learn more about the survival rates of bowel obstruction surgery and factors that increase the risk of severe complications. (healthline.com)
  • In a hospital-based registry, we identified biopsy-proven cases of PTLD among children during a 15-year period and reviewed trends in PTLD rates, the sites of involvement, and the associated survival rates. (bepress.com)
  • Survival rates at 104 weeks among males were 74, 76 and 72 percent, respectively, for groups 1, 2 and 3. (cdc.gov)
  • Corresponding survival rates for females were 86, 78 and 84 percent. (cdc.gov)
  • The technology of organ preservation has improved considerably. (medscape.com)
  • In addition to curative operative intervention, organ protection and preservation are the focus of Dr. Coselli's research. (bcm.edu)
  • A centipede's antennae are crucial sensory organs that aid in navigation and hunting. (whatsthatbug.com)
  • Posttransplant lymphoproliferative disorder (PTLD) is a devastating complication of organ transplant. (bepress.com)
  • Among first episodes of PTLD, T/A PTLD was associated with a survival advantage compared with PTLD at other sites, even after adjustment for potential confounders. (bepress.com)
  • The authors conclude that prolonged exposure to such low concentrations of halothane and nitrous - oxide does not affect body weight, appearance, behavior, survival, or hematology, and does not increase the incidence of reticuloendothelial tumors. (cdc.gov)
  • Here, we investigated the utility of hepatic-, cardiac-, and kidney-derived cell lines to (1) accurately predict cytotoxicity and (2) to accurately predict specific organ toxicities. (nih.gov)
  • Solid-organ transplantations have become the therapeutic option of choice for end-stage organ failure. (medscape.com)
  • A hypernatremia sever ity is often associated with a poor prognosis, especially if it is associated with multiple organ failure. (scirp.org)
  • Objective: To determine the survival benefit of solid-organ transplant as recorded during a 25-year study period in the United Network for Organ Sharing (UNOS) database and the Social Security Administration Death Master File. (houstonmethodist.org)
  • You can also gain two more Pulse Cells by completing the corresponding synergies in the P-Organ, so be sure to pick those along the way, too. (gamespot.com)
  • Much like having more Pulse Cells will increase your odds of survival, so will improving how much they heal you. (gamespot.com)
  • Organ-on-Chip technology with human cells is a promising approach to address these problems. (utwente.nl)
  • They work so closely with human cells that we depend on each other for survival. (amnh.org)
  • They invade other cells for survival and to create more viruses. (amnh.org)
  • Through his study published in the Annals of Thoracic Surgery , he was able to demonstrate the value of using left heart bypass to reduce the problem of inadequate organ blood supply. (bcm.edu)
  • blood is shunted to essential organs (eg, heart, brain). (msdmanuals.com)