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  • Metabolism
  • Forty eight DEGs were shared by both organs, with gene ontology (GO) annotations corresponding to transcription regulation, RNA splicing, sugar metabolism, protein catabolism, immunity, defense against pathogens, and fatty acid biosynthesis. (frontiersin.org)
  • mice
  • We have investigated the induction of DNA-adducts in relation to mutagenesis in bladder and various non-target organs of transgenic Big Blue® mice treated weekly (i.p.) with a representative aromatic-amine compound, 4-aminobiphenyl (4-ABP), for six weeks, followed by a six-week recovery period. (aacrjournals.org)
  • In confirmation, we show a predominant and sustained mutagenic effect of 4-ABP in bladder, and much weaker but significant mutagenicity of 4-ABP in the kidney and liver of carcinogen-treated mice, as reflected by the elevation of background cII mutant frequency in the respective organs. (aacrjournals.org)
  • tissues
  • Here, we provide an organ-wide map of lysine acetylation sites from 16 rat tissues analyzed by high-resolution tandem mass spectrometry. (uzh.ch)
  • Mechanism
  • Archer M.C., Silinskas K.C., Zucker P.F. (1986) Mechanism of Organ Specificity in Nitrosamine Carcinogenesis. (springer.com)
  • This work is revealing that the control of body and organ size does not reside in any specific cellular or molecular mechanism but that it is a systems property in which cellular, physiological and environmental signals all contribute in inextricable ways to produce the final phenotype. (duke.edu)
  • Antigen
  • 0.001) (Table I). Antigen specificity (both against Class I and II) were identified with high frequency only in retransplant and hyperimmune patients (68% and 50% respectively) (Table I). The personal details of the 4 groups differ only in the time of awaiting transplantation which is clearly more than double that of non-immunized patients. (uninet.edu)
  • By targeting an expression pattern instead of a singular antigen, CAR-T specificity for tumor cells can be greatly improved, limiting off-target cellular injury. (beckman.com)
  • Donation
  • This Act clarifies current law in Virginia, addresses the lack of uniformity among states, and brings the law into harmony with federal laws applicable to organ, tissue and eye donation. (richmondsunlight.com)
  • For example, general attitudes toward organ donation are quite positive, but the actual number of people who register as donors is low - a discrepancy that has frustrated and confused researchers. (carrietanasichuk.com)
  • body's
  • To achieve this, there is a multifaceted balancing act between the many activators and suppressors which maintains homeostasis of the body's perhaps most complex organ system. (tebu-bio.com)
  • Cardio exercise and spontaneous physical activity reduce body fat and enhance the efficiency and functional capacity of your heart, lungs, and blood vessels in order to ensure that your body is able to deliver the necessary oxygen, nutrients, and hormones to your body's organs. (ninacheriefranklin.com)
  • hormones
  • These chemical messengers, however, or 'hormones' (from όρμάω, I excite or arouse), as we might call them, have to be carried from the organ where they are produced to the organ which they affect by means of the blood stream and the continually recurring physiological needs of the organism must determine their repeated production and circulation through the body. (todayinsci.com)
  • tumor
  • For this purpose, a model of the blood-brain barrier has been produced, characterized in terms of its morphology and vascular permeability, and then used it to explore extravasation and tumor formation with the brain as the target organ. (selectbiosciences.com)
  • MeSH
  • AnatLab's anatomical objects were categorized using MeSH codes, the National Library of Medicine - Medical Subject Headings codes, which can categorize anatomical structures by body region and by organ system. (nmhmchicago.org)
  • Arabidopsis
  • The second application, to be conducted with the Plant Sciences group at the University of Glasgow, will seek to elucidate, in a model-based inferential manner, the remarkable observed phenomenon of organ specificity of the circadian clock in soybean and Arabidopsis, in addition a study of models of transcriptional regulation in the cell-cycle will be conducted. (ukri.org)
  • PATIENTS
  • Overall 22 organ injuries were detected in 47 patients with CT with sensitivity specificity, Positive and Negative predictive value of 50%, 100% and 69.4% respectively. (edu.et)
  • HERCEPTIN has long been acknowledged that the HERCEPTIN will unlawfully link to the popular breast cancer patients who fail to adhere to safeguards aimed at preventing catastrophic organ failure, should not prevent women from being given it. (20m.com)
  • In one year, 321 organ and tissue transplants of all types were carried out and care was given to 13,000 patients suffering from rare diseases. (zenit.org)
  • remarkable
  • Clearly showing remarkable talent as a player from an early age, Bach's career remained founded upon the organ even as he moved around in a variety of posts after leaving Arnstadt in 1707: as the organist of St Blasius's in Mühlhausen (1707-1708), court organist and chamber musician at Weimar (1708-1717), capellmeister at Cöthen (1717-1723) and cantor at St Thomas' Church in Leipzig (1723 - 1750). (hyperion-records.co.uk)
  • With the ability to mount a response against virtually any foreign material and return to a quiescent state following neutralization of the threat, this fascinating organ system displays remarkable specificity and plasticity. (tebu-bio.com)
  • bones
  • And when Rasmussen takes soil samples at the site of the lungs, liver, kidney, and upper arm muscles ( NOTE THE HOLES IN THE IMAGE ABOVE ), he can - based on the half-life of the element and how quickly it is excreted from a particular organ - develop a much more precise timeline than the bones would divulge. (blogspot.com)
  • It can repair bones and organs. (technovelgy.com)
  • Soil
  • Vine-associated microbial assemblages were influenced by myriad factors that shape their composition and structure, but the majority of organ-associated taxa originated in the soil, and their distribution reflected the influence of highly localized biogeographic factors and vineyard management. (asm.org)
  • genes
  • But the team is also planning to build on what's already known about genes linked to cancer in some organs but not others. (healthwnews.com)
  • However the group can also be planning to construct on what's already identified about genes linked to cancer in some organs however not others. (healthclubb.com)
  • transplants
  • In the light of the foregoing experience, the strategy illustrated in our study showed that a programme, which use an Elisa method to identify anti-HLA class I and II antibody specificities in the transplant candidate, makes it possible, first to perform transplants, and second, to have an acceptable clinical course. (uninet.edu)
  • leaves
  • In this study, the spatial and temporal dynamics of the bacterial communities associated with grapevine organs (leaves, flowers, grapes, and roots) and soils were characterized over two growing seasons to determine the influence of vine cultivar, edaphic parameters, vine developmental stage (dormancy, flowering, preharvest), and vineyard. (asm.org)
  • clinical
  • Immunotherapy has become one of the most popular topics of re-search in the biomedical sciences and shown promise in treating can-cer due to its high target specificity and remission rates in clinical tri-als. (jyi.org)
  • For example, when reporting a CAT of the abdomen of a male, he routinely mentions that "there is no gross abnormalities in the seminal vesicles and prostate," regardless of whether pathology is suspected or absence of pathology in those organs is of clinical relevance. (thehealthcareblog.com)
  • high
  • The best strategy to make grafting possible (as drawn up by the HIT project conducted by the Collaborative Transplant Study between 1986 and 1996), consists in seeking high donor-recipient compatibility after an extensive pre-transplant analysis of antibody specificities, to establish the so-called acceptable incompatibilities . (uninet.edu)
  • Scientific investigators favor the study of the shepherd's purse as a general model of angiosperm embryogenesis because it exhibits a high degree of specificity during embryonic development and is a good representative of the dicotyledonous flowering plants. (fsu.edu)
  • She has a high specificity meaning that when she flags pathology it is very likely to be present. (thehealthcareblog.com)
  • Besides the high-pressure Tuba mirabilis, the organ had two further „Starkton-Register" (strong and expressive in tonal design): Seraphon Gedackt 8' and Seraphon Flöte 8', each with two mouths. (contrebombarde.com)
  • We used a LEGO-like lock-and-key docking system to spatially localize different cell populations with high specificity and precision," Eng explains. (technologynetworks.com)
  • Owing to the non-specificity of drug actions, the increase in drug dosage and course is correspondingly accompanied with a high risk of organ injuries. (ppginco.com)
  • different
  • Knowledge of these acceptable antigens (or epitopes shared by different antigens) comes in useful whenever organ donors are available. (uninet.edu)
  • The analyses using a scanning electron microscope have increased the information on the specificities of the micro-morphological characteristics of different organs of the tree. (cnr.it)
  • Elledge and his group are planning to go back to basics, using healthy cells from 8 different organs and looking at what happens when different DNA faults are introduced. (healthwnews.com)
  • This is where his group will be focusing their efforts, starting with a closer look at what happens when Wnt signalling is out of control in different organs. (healthwnews.com)
  • They'll be monitoring changes in how the DNA is packaged inside cells in different organs and if there are changes to what parts of the DNA code are read and what's made within the cells after they delete the key controller, APC. (healthwnews.com)
  • Elledge and his group are planning to return to fundamentals, utilizing wholesome cells from eight completely different organs and taking a look at what occurs when completely different DNA faults are launched. (healthclubb.com)
  • begun
  • Rehearsals haven't begun, but Krstansky speaks of the production with such specificity, and with such care, it is as if she is collecting pieces of a broken painting that have scattered across a floor. (brandeis.edu)
  • donors
  • By centrally coordinated organ allocation one is thus able to select all the HLA-compatible kidney donors who will presumably give a negative cross-match to all the sera of a given immunized patient. (uninet.edu)
  • characteristic
  • The specific character of the greater part of the toxins which are known to us (I need only instance such toxins as those of tetanus and diphtheria) would suggest that the substances produced for effecting the correlation of organs within the body, through the intermediation of the blood stream, might also belong to this class, since here also specificity of action must be a distinguishing characteristic. (todayinsci.com)
  • cancer
  • In fact, some faults only cause cancer in certain organs in the body, even when every cell in the body also carries that fault. (healthwnews.com)
  • And this is what interests Sansom - the fault is everywhere, but it only causes cancer in certain organs. (healthwnews.com)
  • Sometimes, it is suspected that the impact of persecutors can strike internal organs, cause severe disease (cancer), or even sudden death. (editboard.com)
  • And that is what pursuits Sansom - the fault is all over the place, however it only causes cancer in certain organs. (healthclubb.com)
  • Placed to a commanding height in the NDCR anti-cancer therapy, the reversal of drug resistance will break the barrier for cancer treatment, improve the drug efficacy, and reduce the risk of organ injuries. (ppginco.com)
  • activity
  • NewCardio's product will measure activity throughout the organ, increasing specificity and the ability to properly diagnose, Renz says. (clinpage.com)
  • In the thesis are searched relations that become apparent in connection with administrative-jurisdictional activity of the court in the sphere of the activity of the administrative-jurisdictional organs. (avtoreferat.net)
  • 43.5 million for the annual contribution on the part of the state for the specificity and the activity of the Hospital, 20 million for the financing of research and 3 million euros of donations. (zenit.org)
  • body
  • Only with the advent of the symbolic when language dissects the real, designates an organ as an isolated entity, transforms this thus-designated entity into a signifier, and therefore becomes capable of marking an "absence" of a penis (i.e., a "phallus," insofar as the penis is elevated to the level of a signifier) on woman's body can individuals be said to be "castrated. (lacan.com)
  • Prior to the great experiment a mind/body/spirit was capable of controlling the pressure of blood in the vein, the beating of the organ you call the heart, the intensity of the sensation known to you as pain, and all the functions now understood to be involuntary or unconscious. (lawofone.info)
  • context
  • It's the context of everything else that's around - that's why the question of organ specificity is so complex," he says. (healthwnews.com)
  • It's the context of every little thing else that's round - that's why the query of organ specificity is so complicated," he says. (healthclubb.com)
  • ONHRI's work has to be understood within a context of political competition in the Government of National Unity (GNU) in which self-interest overtook the mandate of the Organ. (accord.org.za)
  • system
  • To maintain, alter the fashion of the Turin L'Ordine Nuovo comrades, that even before the collapse of the bourgeoisie the workers' councils are organs, not only of political struggle, but of technico-economic training in the communist system, can only be seen as a return to socialist gradualism. (libcom.org)
  • Nor can you list common "jargon-y" favorites like "cardiopulmonary arrest," "respiratory failure," "sepsis," or "multi-system organ failure. (thehealthcareblog.com)
  • This video is meant to help you understand how receptor selectivity is related to the organ or system specificity of any given drug. (linneaboyev.com)
  • The team categorized AnatLab's anatomical objects into organ systems to match the nursing curriculum's system approach to teaching anatomy and by anatomical region to match the medical school curriculum. (nmhmchicago.org)
  • important
  • Organ protection is another important aspect of the nourishment. (ppginco.com)
  • Both active and passive verbs allow us to make things more important than simply relocating material from pro- fessional organ izations include those providing facts as well as an established tradition. (matthewswell.com)
  • Purely based on my research and imaginations, I wrote that the project would approach water through important key words in contemporary art and culture such as: archiving, everydayness, interactivity and site-specificity. (activate.zone)
  • cells
  • Eng is excited about leveraging the microtechnologies used to make computer chips with biomedical engineering techniques to make cells to fabricate new organs. (technologynetworks.com)
  • We develop new ideas and methods to try and alleviate disease by assembling tiny subunits of cells into larger, more functional organs," he says. (technologynetworks.com)
  • State
  • This struggle may well be advanced fruitfully by the setting up of workers' representative bodies - but these must be urban or rural workers' councils elected directly by the 'names, waiting to take the place of municipal councils and local organs of State power at the moment the bourgeois forces collapse. (libcom.org)
  • Costs are low on extraversion may be motivated to formance results in price competition, specificity thesis film and secrecy in the state post bureau spb has issued a manifesto called futurist photodynamism. (montessoricentermn.org)
  • Improvement: The study of cultural specificity in "state" senses representation in modern English contributes, on the one hand, to explaining the correlation between language and cognitive structures and, on the other - to issues of intercultural communication. (snu.ac.kr)
  • Challenges
  • After a note on methodology, this is followed by a look at the history of the Organ, its structure, operations and key challenges. (accord.org.za)
  • study
  • HERCEPTIN is reanalyzing another earlier Taxol study, and Moore urged other scientists to claim a specificity in the short term. (20m.com)
  • levels
  • The correlation between plasma and brain concentrations of VitC was moderate compared with other organs, and during non-scorbutic VitC deficiency, the brain was able to maintain concentrations from about one-quarter to half of sufficient levels depending on the region, whereas concentrations in other tissues decreased to one-sixth or less. (nih.gov)
  • various
  • Basically, however, the organ was attuned to German romantic style, with plentiful foundation 8'-stops, differentiation in the manuals according to the various scalings (wide, normal, narrow) and their dynamic gradation (f, mf, p). (contrebombarde.com)
  • unfortunately, almost all chemo- and radiotherapies result into organ damages or even failure as manifested by various adverse effects. (ppginco.com)
  • particular
  • Interestingly, in contrast to other Treg mutants, inflammation is restricted to these particular organs," said Prof. Ishikawa. (medicalxpress.com)
  • To see place as a setting for anecdotes is a slightly more dynamic position, but exotism and lack of exotism are equally powerful in potentially hiding specificity and particular possibilities from view. (blogspot.com)
  • function
  • Current interests are in developing models of healthy and diseased organ function using microfluidic technologies, with a focus on vascularization. (selectbiosciences.com)
  • Surgical procedure must function as last re-sort in treating erectile dysfunction, it's Cialis Canada Pharmacy done to fix blocked yachts that avoid the movement of bloodstream to the organ. (kokura-kumiko.com)
  • without this information, Google's search function loses its specificity. (technovelgy.com)
  • however
  • The work of the Organ did not meet the expectations, however, as it failed to provide any recourse for victims and survivors of violence. (accord.org.za)
  • However, the Organ in Zimbabwe failed to meet any of these requirements. (accord.org.za)
  • Looking at the Organ in Zimbabwe through such conceptual lenses, however, provides a picture of a hastily put together institution, born out of compromise, and without the necessary structural support to perform the job of national healing. (accord.org.za)
  • Search
  • 2) Search for antibody specificities against class I and II HLA antigens, via an ELISA (Sangstat or OneLambda) test (besides standard screening with the complement-dependent cytotoxicity technique (CDC). (uninet.edu)
  • among
  • Modules are characterized by properties such as informational encapsulation, domain-specificity, and automaticity, among others. (rutgers.edu)
  • Among the most numerous are phraseological units, motion verbs reinterpreted in connection with inner organs, emotive interjections, English proverbs and sayings as verbalizations of psychologically significant states. (snu.ac.kr)
  • Along my investigation many things came up - the 2004 Indian Ocean Tsunami, organ trades among the Tsunami victims, farmers' protests against Coca-Cola, sea routes between the two countries, myths and stories about the marriage between an Indian princess and the King of Gaya, an ancient dynasty in Korea, and striking similarities between Tamil and the Korean language, and I ended up writing a rather 'grand' proposal. (activate.zone)
  • But, it cannot be empasised enough, the biographical self is just one epistemological organ among others . (blogspot.com)
  • divisions
  • With theese three loud toned stops, the numerous foundation stops and the two expressive divisions with their sub and superoctave couplers, the organ had an exceptionally broad dynamic spectrum. (contrebombarde.com)
  • life
  • The organ loomed large from early on in Bach's life. (hyperion-records.co.uk)
  • Given that strong foundation, it is no surprise that organ music flowed from Bach's pen throughout his life. (hyperion-records.co.uk)
  • It also provides that taking measures to preserve the viability of organs, tissues and eyes for their donative purpose is not inconsistent with a health-care directive requesting the withholding or withdrawal of life support systems. (richmondsunlight.com)
  • victims
  • The establishment of the Organ was expected to usher in a promising era for most victims of violence in Zimbabwe. (accord.org.za)
  • soon
  • Jerkitude lacking specificity, this was soon elaborated on, but the basic idea persisted: you could venture any opinion you cared to provided you remained civil. (cityweekly.net)
  • work
  • This paper provides an assessment of the work done by the Organ on National Healing, Reconciliation and Integration (ONHRI) in post-2008 Zimbabwe. (accord.org.za)